Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1.

Nonpolarized signaling reveals two distinct modes of 3D cell migration. J Cell Biol (2012) 2.76

The 'invisible hand': regulation of RHO GTPases by RHOGDIs. Nat Rev Mol Cell Biol (2011) 2.39

Rho protein crosstalk: another social network? Trends Cell Biol (2011) 2.19

Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. J Clin Invest (2011) 1.81

ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. J Clin Invest (2013) 1.52

Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells. Nat Cell Biol (2011) 1.51

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study. Mol Cancer (2011) 1.47

The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals. PLoS One (2011) 1.43

Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes. J Am Soc Nephrol (2016) 1.40

The diverse roles of Rac signaling in tumorigenesis. Cell Cycle (2011) 1.38

Symmetry breaking and the establishment of cell polarity in budding yeast. Curr Opin Genet Dev (2011) 1.37

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. EMBO J (2011) 1.36

Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. J Cell Biol (2010) 1.35

Morphogenesis and the cell cycle. Genetics (2012) 1.29

From mechanical force to RhoA activation. Biochemistry (2012) 1.23

The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration. Small GTPases (2014) 1.21

Control of local Rho GTPase crosstalk by Abr. Curr Biol (2011) 1.17

Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops. Nat Commun (2013) 1.13

Rho GTPases in animal cell cytokinesis: an occupation by the one percent. Cytoskeleton (Hoboken) (2012) 1.11

Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding. Mol Cell Biol (2013) 1.06

Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice. J Clin Invest (2011) 1.05

Implications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression. Front Oncol (2013) 1.05

Differential effects of prenylation and s-acylation on type I and II ROPS membrane interaction and function. Plant Physiol (2010) 1.02

Hax1 regulates neutrophil adhesion and motility through RhoA. J Cell Biol (2011) 1.02

ARHGDIA: a novel gene implicated in nephrotic syndrome. J Med Genet (2013) 1.01

RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis. Mol Biol Cell (2011) 1.00

Intestinal Salmonella typhimurium infection leads to miR-29a induced caveolin 2 regulation. PLoS One (2013) 0.99

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. Cancer Res (2013) 0.97

αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion. Mol Biol Cell (2013) 0.97

Rho GTPases in collective cell migration. Small GTPases (2014) 0.96

A density-dependent switch drives stochastic clustering and polarization of signaling molecules. PLoS Comput Biol (2011) 0.95

Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation. Am J Physiol Cell Physiol (2011) 0.94

Regulation of Rac1 translocation and activation by membrane domains and their boundaries. J Cell Sci (2014) 0.94

Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking. Small GTPases (2014) 0.93

Suppression of Rac1 activity at the apical membrane of MDCK cells is essential for cyst structure maintenance. EMBO Rep (2012) 0.93

MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells. Mol Biol Cell (2015) 0.93

The three-way switch operation of Rac1/RhoA GTPase-based circuit controlling amoeboid-hybrid-mesenchymal transition. Sci Rep (2014) 0.92

Rho GTPase regulation by miRNAs and covalent modifications. Trends Cell Biol (2012) 0.90

A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging. PLoS One (2014) 0.90

RhoA phosphorylation induces Rac1 release from guanine dissociation inhibitor alpha and stimulation of vascular smooth muscle cell migration. Mol Cell Biol (2010) 0.90

RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells. Cell Death Dis (2013) 0.90

Rho/ROCK signaling in motility and metastasis of gastric cancer. World J Gastroenterol (2014) 0.90

Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. Pharmacol Ther (2014) 0.90

RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac. J Cell Biochem (2011) 0.90

Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation. J Biol Chem (2012) 0.89

Phosphorylation of EBP50 negatively regulates β-PIX-dependent Rac1 activity in anoikis. Cell Death Differ (2012) 0.89

RhoGDI2 antagonizes ovarian carcinoma growth, invasion and metastasis. Small GTPases (2011) 0.89

Signaling networks regulating leukocyte podosome dynamics and function. Cell Signal (2011) 0.88

UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph polarize F-actin during embryonic morphogenesis by regulating the WAVE/SCAR actin nucleation complex. PLoS Genet (2012) 0.88

Rac-ing to the plasma membrane: the long and complex work commute of Rac1 during cell signaling. Small GTPases (2012) 0.88

Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nat Commun (2013) 0.87

CD98hc (SLC3A2) regulation of skin homeostasis wanes with age. J Exp Med (2013) 0.86

PKCα phosphorylation of RhoGDI2 at Ser31 disrupts interactions with Rac1 and decreases GDI activity. Oncogene (2012) 0.86

Quantitative analysis of membrane trafficking in regulation of Cdc42 polarity. Traffic (2014) 0.85

SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation. FASEB J (2013) 0.85

Cadherin point mutations alter cell sorting and modulate GTPase signaling. J Cell Sci (2012) 0.85

Function and regulation of Rnd proteins in cortical projection neuron migration. Front Neurosci (2015) 0.85

Positive roles for negative regulators in the mating response of yeast. Mol Syst Biol (2012) 0.85

Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration. Breast Cancer Res (2013) 0.85

The Fer tyrosine kinase regulates interactions of Rho GDP-Dissociation Inhibitor α with the small GTPase Rac. BMC Biochem (2010) 0.84

Computational analysis of Rho GTPase cycling. PLoS Comput Biol (2013) 0.84

RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer. Mol Cancer Res (2014) 0.83

Autophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins. Autophagy (2013) 0.83

Protein tyrosine phosphatase-PEST and β8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells. Mol Cell Biol (2015) 0.83

The Rac1 hypervariable region in targeting and signaling: a tail of many stories. Small GTPases (2013) 0.83

Role of βPix in the Kidney. Front Physiol (2012) 0.83

Targeting of the small GTPase Rab6A' by the Legionella pneumophila effector LidA. Infect Immun (2013) 0.82

Comprehensive identification of SUMO2/3 targets and their dynamics during mitosis. PLoS One (2014) 0.82

Rho GAPs and GEFs: controling switches in endothelial cell adhesion. Cell Adh Migr (2014) 0.82

Downregulation of ARHGDIA contributes to human glioma progression through activation of Rho GTPase signaling pathway. Tumour Biol (2016) 0.82

Expression loss and revivification of RhoB gene in ovary carcinoma carcinogenesis and development. PLoS One (2013) 0.81

Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism. Mol Biol Cell (2012) 0.81

The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1. J Cell Biol (2013) 0.80

Controlling the switches: Rho GTPase regulation during animal cell mitosis. Cell Signal (2014) 0.80

FERM domain containing protein 7 interacts with the Rho GDP dissociation inhibitor and specifically activates Rac1 signaling. PLoS One (2013) 0.80

Crosstalk of small GTPases at the Golgi apparatus. Small GTPases (2012) 0.79

IAPs as E3 ligases of Rac1: shaping the move. Small GTPases (2012) 0.79

Rho proteins crosstalk via RhoGDIalpha: At random or hierarchically ordered? Commun Integr Biol (2012) 0.79

RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoA. Vasc Cell (2012) 0.78

Changes in the GEF-H1 pathways after traumatic brain injury. J Neurotrauma (2013) 0.78

Regulation of cerebral cortex development by Rho GTPases: insights from in vivo studies. Front Cell Neurosci (2015) 0.78

FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions. Nat Chem Biol (2016) 0.77

RhoGDI deficiency induces constitutive activation of Rho GTPases and COX-2 pathways in association with breast cancer progression. Oncotarget (2015) 0.77

A novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivo. Sci Rep (2015) 0.77

Integrated analysis of global mRNA and protein expression data in HEK293 cells overexpressing PRL-1. PLoS One (2013) 0.77

The role of Nox-mediated oxidation in the regulation of cytoskeletal dynamics. Curr Pharm Des (2015) 0.77

Arabidopsis RhoGDIs Are Critical for Cellular Homeostasis of Pollen Tubes. Plant Physiol (2015) 0.77

RhoGDI2 up-regulates P-glycoprotein expression via Rac1 in gastric cancer cells. Cancer Cell Int (2015) 0.77

Intracellular expression of Tat alters mitochondrial functions in T cells: a potential mechanism to understand mitochondrial damage during HIV-1 replication. Retrovirology (2015) 0.77

Rho GTPases and actomyosin: Partners in regulating epithelial cell-cell junction structure and function. Exp Cell Res (2017) 0.76

Zds1/Zds2-PP2ACdc55 complex specifies signaling output from Rho1 GTPase. J Cell Biol (2016) 0.76

Rnd3 as a Novel Target to Ameliorate Microvascular Leakage. J Am Heart Assoc (2016) 0.76

A unique carboxyl-terminal insert domain in the hematopoietic-specific, GTPase-deficient Rho GTPase RhoH regulates post-translational processing. J Biol Chem (2013) 0.76

A dual role model for active Rac1 in cell migration. Small GTPases (2013) 0.76

Deregulation of Rho GTPases in cancer. Small GTPases (2016) 0.76

Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain. J Neurochem (2014) 0.75

Disease-causing mutations of RhoGDIα induce Rac1 hyperactivation in podocytes. Small GTPases (2016) 0.75

Tools for Live Imaging of Active Rho GTPases in Xenopus. Genesis (2017) 0.75

TROY interacts with Rho guanine nucleotide dissociation inhibitor α (RhoGDIα) to mediate Nogo-induced inhibition of neurite outgrowth. J Biol Chem (2013) 0.75

Rho GTPases in ameloblast differentiation. Jpn Dent Sci Rev (2015) 0.75

Genomic analysis of metastasis reveals an essential role for RhoC. Nature (2000) 10.11

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J (1999) 9.76

Pathways of chaperone-mediated protein folding in the cytosol. Nat Rev Mol Cell Biol (2004) 6.45

Design of a genome-wide siRNA library using an artificial neural network. Nat Biotechnol (2005) 5.60

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding. J Cell Biol (2001) 5.05

GDIs: central regulatory molecules in Rho GTPase activation. Trends Cell Biol (2005) 4.13

Guide to yeast genetics and molecular biology. Methods Enzymol (1991) 3.61

CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion. Cell (2002) 2.77

A novel regulator of p21-activated kinases. J Biol Chem (1998) 2.60

Post-prenylation-processing enzymes as new targets in oncogenesis. Nat Rev Cancer (2005) 2.47

Analysis of activated GAPs and GEFs in cell lysates. Methods Enzymol (2006) 2.45

Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease. Nat Med (2008) 2.25

Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein. J Biol Chem (1990) 2.09

RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circ Res (2007) 1.99

Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. J Cell Biol (2001) 1.94

Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIalpha. Oncogene (1999) 1.91

RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration. J Cell Biol (2007) 1.71

RhoG signals in parallel with Rac1 and Cdc42. J Biol Chem (2002) 1.70

Regulation of Rho family GTPases by cell-cell and cell-matrix adhesion. Biol Res (2002) 1.63

A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. Science (1992) 1.58

Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein-mediated zone of inhibition. J Cell Biol (2007) 1.54

Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases. Proc Natl Acad Sci U S A (2003) 1.54

The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms. Mol Biol Cell (2008) 1.27

Lack of GTP-bound Rho1p in secretory vesicles of Saccharomyces cerevisiae. J Cell Biol (2003) 1.24

ILK is required for the assembly of matrix-forming adhesions and capillary morphogenesis in endothelial cells. J Cell Sci (2004) 1.13

SnapShot: Rho family GTPases. Cell (2007) 1.10

Morphological and proliferative abnormalities in renal mesangial cells lacking RhoGDI. Cell Signal (2009) 1.01

Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors. J Biol Chem (2004) 0.99

Cell migration: integrating signals from front to back. Science (2003) 29.13

Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol (2003) 3.11

Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion. J Cell Biol (2002) 2.99

ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. J Immunol (2007) 2.66

Analysis of activated GAPs and GEFs in cell lysates. Methods Enzymol (2006) 2.45

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins. Nat Cell Biol (2011) 2.45

The 'invisible hand': regulation of RHO GTPases by RHOGDIs. Nat Rev Mol Cell Biol (2011) 2.39

RhoA is required for cortical retraction and rigidity during mitotic cell rounding. J Cell Biol (2003) 2.34

Serine phosphorylation negatively regulates RhoA in vivo. J Biol Chem (2003) 2.28

Rho protein crosstalk: another social network? Trends Cell Biol (2011) 2.19

RhoA and ROCK promote migration by limiting membrane protrusions. J Biol Chem (2003) 2.17

Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton. J Cell Biol (2004) 2.16

Simultaneous stretching and contraction of stress fibers in vivo. Mol Biol Cell (2004) 2.12

Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration. J Biol Chem (2006) 2.07

Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function. J Biol Chem (2005) 1.84

Rnd proteins function as RhoA antagonists by activating p190 RhoGAP. Curr Biol (2003) 1.84

Catching a GEF by its tail. Trends Cell Biol (2006) 1.79

XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC. J Biol Chem (2002) 1.78

VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2. Exp Cell Res (2007) 1.76

The ghost in the machine: small GTPases as spatial regulators of exocytosis. Trends Cell Biol (2008) 1.75

RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration. J Cell Biol (2007) 1.71

RhoG signals in parallel with Rac1 and Cdc42. J Biol Chem (2002) 1.70

The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. J Biol Chem (2009) 1.69

Regulation of Rho family GTPases by cell-cell and cell-matrix adhesion. Biol Res (2002) 1.63

A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin. J Cell Sci (2007) 1.63

Coupling membrane protrusion and cell adhesion. J Cell Sci (2003) 1.61

Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains. J Cell Biochem (2006) 1.56

Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells. Mol Biol Cell (2002) 1.54

Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex. J Cell Biol (2005) 1.51

Cadherin engagement inhibits RhoA via p190RhoGAP. J Biol Chem (2003) 1.50

Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif. PLoS One (2009) 1.46

Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cells. J Cell Sci (2006) 1.45

Proline-rich tyrosine kinase 2 (Pyk2) mediates vascular endothelial-cadherin-based cell-cell adhesion by regulating beta-catenin tyrosine phosphorylation. J Biol Chem (2005) 1.45

The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals. PLoS One (2011) 1.43

COPI recruitment is modulated by a Rab1b-dependent mechanism. Mol Biol Cell (2003) 1.42

SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis. Mol Biol Cell (2004) 1.42

Biomedical research publication system. Science (2004) 1.39

Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism. Nature (2007) 1.36

The vinculin C-terminal hairpin mediates F-actin bundle formation, focal adhesion, and cell mechanical properties. J Biol Chem (2011) 1.32

Regulation of cell adhesion by protein-tyrosine phosphatases: II. Cell-cell adhesion. J Biol Chem (2006) 1.29

The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery. Mol Biol Cell (2004) 1.25

Chapter 1. Focal adhesions: new angles on an old structure. Int Rev Cell Mol Biol (2009) 1.24

PTP-PEST controls motility through regulation of Rac1. J Cell Sci (2002) 1.24

From mechanical force to RhoA activation. Biochemistry (2012) 1.23

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway. Curr Biol (2012) 1.20

Dissection of membrane dynamics of the ARF-guanine nucleotide exchange factor GBF1. Traffic (2005) 1.20

Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions. J Cell Biol (2014) 1.19

Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema. Am J Physiol Lung Cell Mol Physiol (2009) 1.15

PTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP. J Biol Chem (2006) 1.14

SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC. J Biol Chem (2011) 1.13

Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast. Traffic (2005) 1.09

Trading spaces: Rap, Rac, and Rho as architects of transendothelial migration. Curr Opin Hematol (2005) 1.09

Front and back by Rho and Rac. Nat Cell Biol (2006) 1.09

Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors. Mol Biol Cell (2010) 1.08

MLK3 limits activated Galphaq signaling to Rho by binding to p63RhoGEF. Mol Cell (2008) 1.07

The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity. Mol Cell Biol (2007) 1.07

Isoform-specific differences between Rap1A and Rap1B GTPases in the formation of endothelial cell junctions. Small GTPases (2011) 1.07

The role of vascular endothelial growth factor-induced activation of NADPH oxidase in choroidal endothelial cells and choroidal neovascularization. Am J Pathol (2010) 1.06

Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation. Cardiovasc Res (2006) 1.04

Focal adhesion kinase regulates cell-cell contact formation in epithelial cells via modulation of Rho. Exp Cell Res (2008) 1.04

Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells. Stem Cells (2011) 1.04

The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage. PLoS One (2011) 1.02

I'm coming to GEF you: Regulation of RhoGEFs during cell migration. Cell Adh Migr (2014) 1.02

Heterotypic RPE-choroidal endothelial cell contact increases choroidal endothelial cell transmigration via PI 3-kinase and Rac1. Exp Eye Res (2006) 1.02

Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. J Biol Chem (2004) 1.02

Structurally conserved interaction of Lgl family with SNAREs is critical to their cellular function. Curr Biol (2005) 1.01

Spatial regulation of exocytosis and cell polarity: yeast as a model for animal cells. FEBS Lett (2007) 1.00

Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration. PLoS One (2013) 1.00

Latent KSHV infection increases the vascular permeability of human endothelial cells. Blood (2011) 1.00

The role of RPE cell-associated VEGF₁₈₉ in choroidal endothelial cell transmigration across the RPE. Invest Ophthalmol Vis Sci (2011) 0.99

Def-6, a guanine nucleotide exchange factor for Rac1, interacts with the skeletal muscle integrin chain alpha7A and influences myoblast differentiation. J Biol Chem (2007) 0.97

Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. Biochim Biophys Acta (2008) 0.97

Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. J Cell Sci (2009) 0.95

Regulation of Rho proteins by phosphorylation in the cardiovascular system. Trends Cardiovasc Med (2006) 0.94

Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation. PLoS One (2012) 0.92

The invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity. PLoS Pathog (2012) 0.92

IpaA targets beta1 integrins and rho to promote actin cytoskeleton rearrangements necessary for Shigella entry. J Biol Chem (2006) 0.91

Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells. J Biol Chem (2009) 0.90

The yeast tumor suppressor homologue Sro7p is required for targeting of the sodium pumping ATPase to the cell surface. Mol Biol Cell (2006) 0.90

AMPK alpha 1-induced RhoA phosphorylation mediates vasoprotective effect of estradiol. Arterioscler Thromb Vasc Biol (2011) 0.90

The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration. J Immunol (2014) 0.89

Cell biology: a break in the chain? Nature (2006) 0.88

Off the beaten paths: alternative and crosstalk regulation of Rho GTPases. FASEB J (2011) 0.88

Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells. Stem Cells (2013) 0.88

Golgi membrane dynamics and lipid metabolism. Curr Biol (2012) 0.88

Analysis of low molecular weight GTPase activity in endothelial cell cultures. Methods Enzymol (2008) 0.87

RhoGDI: A rheostat for the Rho switch. Small GTPases (2010) 0.87

The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis. PLoS One (2013) 0.85

Quantitative analysis of membrane trafficking in regulation of Cdc42 polarity. Traffic (2014) 0.85

Vinculin regulation of F-actin bundle formation: what does it mean for the cell? Cell Adh Migr (2013) 0.84