Published in J Oral Pathol Med on May 01, 2004
Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms. J Clin Microbiol (2004) 1.91
Innate immune peptide LL-37 displays distinct expression pattern from beta-defensins in inflamed gingival tissue. Clin Exp Immunol (2006) 1.14
Human alpha- and beta-defensins bind to immobilized adhesins from Porphyromonas gingivalis. Infect Immun (2008) 0.95
Defensins as anti-inflammatory compounds and mucosal adjuvants. Future Microbiol (2010) 0.95
Antimicrobial peptides in periodontal innate defense. Front Oral Biol (2011) 0.91
Induction of {beta}-defensin resistance in the oral anaerobe Porphyromonas gingivalis. Antimicrob Agents Chemother (2005) 0.90
Susceptibility of Streptococcus mutans and Actinobacillus actinomycetemcomitans to bactericidal activity of human beta-defensin 3 in biological fluids. Antimicrob Agents Chemother (2005) 0.87
Understanding the roles of gingival beta-defensins. J Oral Microbiol (2012) 0.86
Effects of fruit and vegetable low molecular mass fractions on gene expression in gingival cells challenged with Prevotella intermedia and Actinomyces naeslundii. J Biomed Biotechnol (2011) 0.84
Increased human defensine levels hint at an inflammatory etiology of bisphosphonate-associated osteonecrosis of the jaw: an immunohistological study. J Transl Med (2011) 0.80
Low DEFB4 copy number and high systemic hBD-2 and IL-22 levels are associated with dermatophytosis. J Invest Dermatol (2014) 0.80
Concern Effect of human beta-defensin-3 on head and neck cancer cell migration using micro-fabricated cell islands. Head Neck Oncol (2012) 0.80
Human beta-defensin-1 suppresses tumor migration and invasion and is an independent predictor for survival of oral squamous cell carcinoma patients. PLoS One (2014) 0.79
Induction of β-Defensin Expression by Porphyromonas gingivalis-Infected Human Gingival Graft Transplanted in nu/nu Mouse Subdermis. Acta Histochem Cytochem (2013) 0.78
Gene polymorphism of β-defensin-1 is associated with susceptibility to periodontitis in Japanese. Odontology (2013) 0.77
Capacity of human beta-defensin expression in gene-transduced and cytokine-induced cells. Biochem Biophys Res Commun (2005) 0.77
In vivo beta-defensin gene expression in rat gingival epithelium in response to Actinobacillus actinomycetemcomitans infection. J Periodontal Res (2006) 0.76
Biocompatibility of pure and mixed hydroxyapatite and α-tricalcium phosphate implanted in rabbit bone. J Mater Sci Mater Med (2015) 0.76
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell (2008) 11.24
Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science (2008) 6.28
Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445]. Crit Care (2005) 4.14
Current prospects for RNA interference-based therapies. Nat Rev Genet (2011) 3.63
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Sci Transl Med (2010) 3.36
Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Nature (2011) 2.94
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature (2012) 2.94
The emergency department utility of Simplify D-dimer to exclude pulmonary embolism in patients with pleuritic chest pain. Ann Emerg Med (2005) 2.81
A novel host defense system of airways is defective in cystic fibrosis. Am J Respir Crit Care Med (2006) 2.61
Discovery of five conserved beta -defensin gene clusters using a computational search strategy. Proc Natl Acad Sci U S A (2002) 2.56
The porcine lung as a potential model for cystic fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 2.53
Cytokine-mediated regulation of antimicrobial proteins. Nat Rev Immunol (2008) 2.46
Human polymicrobial infections. Lancet (2005) 2.34
Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed. J Clin Invest (2008) 2.21
The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus. J Biol Chem (2001) 2.20
Rapid generation of a mouse model for Middle East respiratory syndrome. Proc Natl Acad Sci U S A (2014) 2.17
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus. Proc Natl Acad Sci U S A (2011) 2.12
The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Sci Transl Med (2011) 2.01
Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children. Am J Respir Crit Care Med (2010) 1.94
Ebola virus glycoprotein 1: identification of residues important for binding and postbinding events. J Virol (2007) 1.93
Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms. J Clin Microbiol (2004) 1.91
Correlation between beta-defensin expression and induction profiles in gingival keratinocytes. Mol Immunol (2004) 1.90
Antimicrobial peptides in animals and their role in host defences. Int J Antimicrob Agents (2003) 1.84
Ca3 fingerprinting of Candida albicans isolates from human immunodeficiency virus-positive and healthy individuals reveals a new clade in South Africa. J Clin Microbiol (2002) 1.81
The NLRP3 inflammasome: a sensor of immune danger signals. Semin Immunol (2009) 1.81
[beta]-defensins in lung host defense. Annu Rev Physiol (2002) 1.80
Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2. Am J Physiol Lung Cell Mol Physiol (2004) 1.64
The nervous system and innate immunity: the neuropeptide connection. Nat Immunol (2005) 1.63
The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia. Am J Physiol Lung Cell Mol Physiol (2010) 1.61
Innate immune functions of the airway epithelium. Contrib Microbiol (2008) 1.57
Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis. Am J Respir Crit Care Med (2006) 1.56
Changes in central venous saturation after major surgery, and association with outcome. Crit Care (2005) 1.53
Identification of four distinct genotypes of Candida dubliniensis and detection of microevolution in vitro and in vivo. J Clin Microbiol (2002) 1.49
Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization. J Am Chem Soc (2011) 1.48
miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production. Am J Respir Crit Care Med (2014) 1.45
Shade-match perception of porcelain-fused-to-metal restorations: a comparison between dentist and patient. J Am Dent Assoc (2002) 1.45
Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha. J Virol (2003) 1.45
PLUNC is a novel airway surfactant protein with anti-biofilm activity. PLoS One (2010) 1.44
Susceptibility of nontypeable Haemophilus influenzae to human beta-defensins is influenced by lipooligosaccharide acylation. Infect Immun (2002) 1.40
Phenotypic switching and filamentation in Candida glabrata. Microbiology (2002) 1.38
Factors related to utilization of dental services during pregnancy. J Clin Periodontol (2005) 1.38
piggyBac transposase tools for genome engineering. Proc Natl Acad Sci U S A (2013) 1.35
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. J Clin Invest (2013) 1.30
CCL20 is an inducible product of human airway epithelia with innate immune properties. Am J Respir Cell Mol Biol (2003) 1.28
Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection. J Virol (2014) 1.25
Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins. J Immunol (2003) 1.24
Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein. Virology (2011) 1.22
Integration site choice of a feline immunodeficiency virus vector. J Virol (2006) 1.20
Human beta-defensin 3 binds to hemagglutinin B (rHagB), a non-fimbrial adhesin from Porphyromonas gingivalis, and attenuates a pro-inflammatory cytokine response. Immunol Cell Biol (2008) 1.20
Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors. J Virol (2009) 1.20
The impact of cigarette smoking on periodontal disease and treatment. Periodontol 2000 (2007) 1.19
Measles virus preferentially transduces the basolateral surface of well-differentiated human airway epithelia. J Virol (2002) 1.18
Influence of smoking on gingival crevicular fluid cytokines in severe chronic periodontitis. J Clin Periodontol (2010) 1.18
Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer. J Virol (2005) 1.18
Expression and activity of beta-defensins and LL-37 in the developing human lung. J Immunol (2005) 1.17
NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells. Nature (2012) 1.16
In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteins. J Virol (2002) 1.16
Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae. J Virol (2009) 1.15
Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer. Blood (2005) 1.14
ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol (2005) 1.14
Impact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides. Protein Eng (2002) 1.14
PLUNC is a secreted product of neutrophil granules. J Leukoc Biol (2008) 1.13
Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth. Proc Natl Acad Sci U S A (2010) 1.12
MD-2-dependent pulmonary immune responses to inhaled lipooligosaccharides: effect of acylation state. Am J Respir Cell Mol Biol (2008) 1.11
A microRNA-regulated and GP64-pseudotyped lentiviral vector mediates stable expression of FVIII in a murine model of Hemophilia A. Mol Ther (2011) 1.11
In vitro fracture resistance of endodontically treated central incisors with varying ferrule heights and configurations. J Prosthet Dent (2005) 1.10
The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor. Biomaterials (2013) 1.10
CFTR DeltaF508 mutation has minimal effect on the gene expression profile of differentiated human airway epithelia. Am J Physiol Lung Cell Mol Physiol (2005) 1.09
Burden of disease associated with alcohol use disorders in the United States. Alcohol Clin Exp Res (2014) 1.09
SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection. Am J Pathol (2013) 1.08
Advances in cell and gene-based therapies for cystic fibrosis lung disease. Mol Ther (2012) 1.08
A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci U S A (2012) 1.07
Lentivirus vector can be readministered to nasal epithelia without blocking immune responses. J Virol (2008) 1.07
Bacterial penetration through canals of endodontically treated teeth in the presence or absence of the smear layer. J Dent (2003) 1.07
Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia. Am J Physiol Lung Cell Mol Physiol (2009) 1.06
Carriage frequency, intensity of carriage, and strains of oral yeast species vary in the progression to oral candidiasis in human immunodeficiency virus-positive individuals. J Clin Microbiol (2002) 1.05
Viral vector-mediated and cell-based therapies for treatment of cystic fibrosis. Mol Ther (2007) 1.05
Differential effects of cytokines and corticosteroids on toll-like receptor 2 expression and activity in human airway epithelia. Respir Res (2009) 1.02
Person-to-person spread of the MERS coronavirus--an evolving picture. N Engl J Med (2013) 1.02
Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis. Laryngoscope (2012) 1.02
PLUNC: a multifunctional surfactant of the airways. Biochem Soc Trans (2011) 1.01
Large-scale gene discovery in human airway epithelia reveals novel transcripts. Physiol Genomics (2004) 1.01
Enhancement of respiratory mucosal antiviral defenses by the oxidation of iodide. Am J Respir Cell Mol Biol (2011) 0.97
The effect of inmate populations on estimates of DSM-IV alcohol and drug use disorders in the United States. Am J Psychiatry (2010) 0.96
Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. J Virol (2009) 0.96
Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections. J Virol (2012) 0.95
Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors. Am J Respir Cell Mol Biol (2005) 0.95
Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector. Hum Gene Ther (2007) 0.94
Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. Am J Respir Crit Care Med (2012) 0.94
Developmental expression and distribution of sheep beta-defensin-2. Dev Comp Immunol (2004) 0.94
Best evidence topic report. Low molecular weight heparin for intravenous drug users with deep vein thrombosis. Emerg Med J (2004) 0.94