PubRank

Peter Donnelly

Author PubWeight™ 528.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 85.39
2 A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 2007 52.68
3 A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet 2009 30.09
4 A fine-scale map of recombination rates and hotspots across the human genome. Science 2005 26.82
5 A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 2003 26.59
6 Genome-wide detection and characterization of positive selection in human populations. Nature 2007 17.27
7 The fine-scale structure of recombination rate variation in the human genome. Science 2004 17.05
8 Replicating genotype-phenotype associations. Nature 2007 16.11
9 The effects of human population structure on large genetic association studies. Nat Genet 2004 14.88
10 Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet 2005 14.88
11 New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet 2007 13.76
12 Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011 13.23
13 Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007 12.62
14 A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet 2006 12.45
15 Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 2010 12.27
16 Transcriptome and genome sequencing uncovers functional variation in humans. Nature 2013 8.89
17 A common sequence motif associated with recombination hot spots and genome instability in humans. Nat Genet 2008 8.64
18 A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 2010 8.48
19 Comparison of fine-scale recombination rates in humans and chimpanzees. Science 2005 7.86
20 Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 2013 7.44
21 Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination. Science 2009 7.35
22 Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet 2009 6.61
23 Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet 2012 6.25
24 Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet 2011 5.56
25 Accessibility, sustainability, excellence: how to expand access to research publications. Executive summary. Int Microbiol 2013 4.66
26 A statistical method for predicting classical HLA alleles from SNP data. Am J Hum Genet 2008 4.65
27 Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet 2013 4.62
28 Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet 2009 4.61
29 Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet 2010 4.42
30 Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet 2009 4.30
31 The influence of recombination on human genetic diversity. PLoS Genet 2006 4.04
32 Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet 2012 3.40
33 Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet 2010 3.34
34 Human recombination hot spots hidden in regions of strong marker association. Nat Genet 2005 3.33
35 Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet 2012 3.31
36 Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease. Proc Natl Acad Sci U S A 2012 3.29
37 Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet 2013 2.87
38 A fine-scale chimpanzee genetic map from population sequencing. Science 2012 2.83
39 Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature 2012 2.66
40 HAPGEN2: simulation of multiple disease SNPs. Bioinformatics 2011 2.58
41 Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science 2013 2.32
42 A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS Genet 2011 1.83
43 Is mate choice in humans MHC-dependent? PLoS Genet 2008 1.66
44 Including known covariates can reduce power to detect genetic effects in case-control studies. Nat Genet 2012 1.66
45 Recombination and population structure in Salmonella enterica. PLoS Genet 2011 1.61
46 Human metabolic profiles are stably controlled by genetic and environmental variation. Mol Syst Biol 2011 1.60
47 Application of coalescent methods to reveal fine-scale rate variation and recombination hotspots. Genetics 2004 1.59
48 People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population. Eur J Hum Genet 2011 1.58
49 Gang membership, violence, and psychiatric morbidity. Am J Psychiatry 2013 1.54
50 Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet 2012 1.52
51 Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event. Nat Genet 2012 1.43
52 Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency. Neuron 2010 1.33
53 Quantifying the underestimation of relative risks from genome-wide association studies. PLoS Genet 2011 1.30
54 High recombination rate in herpes simplex virus type 1 natural populations suggests significant co-infection. Infect Genet Evol 2004 1.23
55 A robust clustering algorithm for identifying problematic samples in genome-wide association studies. Bioinformatics 2011 1.19
56 Congenital myasthenic syndromes due to mutations in ALG2 and ALG14. Brain 2013 1.18
57 Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet 2013 1.15
58 Disease model distortion in association studies. Genet Epidemiol 2011 1.14
59 Recessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor development. PLoS Genet 2012 1.14
60 Economic instruments for obesity prevention: results of a scoping review and modified Delphi survey. Int J Behav Nutr Phys Act 2011 1.05
61 A model-based approach to capture genetic variation for future association studies. Genome Res 2006 1.05
62 Genomic tools for evolution and conservation in the chimpanzee: Pan troglodytes ellioti is a genetically distinct population. PLoS Genet 2012 1.00
63 Gene-gene interactions in breast cancer susceptibility. Hum Mol Genet 2011 0.97
64 Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I. Haematologica 2013 0.95
65 Bayesian hierarchical mixture modeling to assign copy number from a targeted CNV array. Genet Epidemiol 2011 0.93
66 Patterns of Eurasian HSV-1 molecular diversity and inferences of human migrations. Infect Genet Evol 2005 0.90
67 Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger? Ann Hematol 2003 0.88
68 A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. Biol Psychiatry 2013 0.87
69 Systematic review of validity testing in colonoscopy simulation. Surg Endosc 2012 0.86
70 The antimicrobial effect of Iseganan HCl oral solution in patients receiving stomatotoxic chemotherapy: analysis from a multicenter, double-blind, placebo-controlled, randomized, phase III clinical trial. J Oral Pathol Med 2011 0.85
71 Options for early breast cancer follow-up in primary and secondary care - a systematic review. BMC Cancer 2012 0.84
72 Effectiveness of an educational video on concussion knowledge in minor league hockey players: a cluster randomised controlled trial. Br J Sports Med 2013 0.84
73 Experiments with the site frequency spectrum. Bull Math Biol 2010 0.81
74 Assessing association between protein truncating variants and quantitative traits. Bioinformatics 2013 0.78
75 The role of ATM in response to metformin treatment and activation of AMPK. Nat Genet 2012 0.77
76 Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people. Cochrane Database Syst Rev 2015 0.77
77 Differences in UK health care after devolution. BMJ 2010 0.75
78 A scientific and psychosocial environmental investigation tool: the Meeting, Understanding, Surveillance, Toxicology, Evaluation and Reporting (MUSTER) model. Postgrad Med J 2011 0.75
79 Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people. Cochrane Database Syst Rev 2015 0.75
80 Software process improvement for the medical industry. Stud Health Technol Inform 2005 0.75
81 A review of quality assessment of the methodology used in guidelines and systematic reviews on oral mucositis. J Clin Nurs 2009 0.75