Published in Blood on August 05, 2004
Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences. Genome Res (2005) 7.09
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy (2016) 7.05
Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol (2006) 5.01
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol (2008) 4.56
Discovering sequence motifs with arbitrary insertions and deletions. PLoS Comput Biol (2008) 4.10
Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell (2009) 3.96
Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus. Mol Cell (2008) 3.24
A GATA-1-regulated microRNA locus essential for erythropoiesis. Proc Natl Acad Sci U S A (2008) 3.10
Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol Cell (2009) 3.05
Mulan: multiple-sequence local alignment and visualization for studying function and evolution. Genome Res (2004) 2.91
Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res (2009) 2.64
GATA-1 forms distinct activating and repressive complexes in erythroid cells. EMBO J (2005) 2.56
GATA1 function, a paradigm for transcription factors in hematopoiesis. Mol Cell Biol (2005) 2.55
FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. EMBO J (2005) 2.53
Foxo3 is required for the regulation of oxidative stress in erythropoiesis. J Clin Invest (2007) 2.39
A global role for EKLF in definitive and primitive erythropoiesis. Blood (2005) 2.24
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood (2008) 2.19
GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein. Proc Natl Acad Sci U S A (2008) 2.17
GATA-1 directly regulates p21 gene expression during erythroid differentiation. Cell Cycle (2010) 2.17
Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Blood (2013) 2.12
An unmethylated 3' promoter-proximal region is required for efficient transcription initiation. PLoS Genet (2007) 2.11
Altered translation of GATA1 in Diamond-Blackfan anemia. Nat Med (2014) 2.11
A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression. Cell Metab (2009) 2.10
Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling. Proc Natl Acad Sci U S A (2006) 2.08
Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Res (2011) 2.07
Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis. Genes Dev (2008) 2.05
A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells. Genome Res (2010) 2.02
Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region. Proc Natl Acad Sci U S A (2005) 1.96
Distinct functions of dispersed GATA factor complexes at an endogenous gene locus. Mol Cell Biol (2006) 1.94
Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes. Mol Cell Biol (2007) 1.84
miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta. Genes Dev (2010) 1.80
Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage. J Exp Med (2008) 1.79
Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1. Nucleic Acids Res (2009) 1.76
Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell (2012) 1.74
EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice. Mol Cell Biol (2007) 1.72
Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1. Blood (2005) 1.72
Experimental validation of predicted mammalian erythroid cis-regulatory modules. Genome Res (2006) 1.71
ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis. Mol Cell Biol (2005) 1.70
Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation. Mol Cell Biol (2005) 1.67
NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. EMBO J (2009) 1.66
Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell (2014) 1.64
Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway. Blood (2005) 1.63
Variegated gene expression caused by cell-specific long-range DNA interactions. Nat Cell Biol (2011) 1.63
Ontogeny of erythroid gene expression. Blood (2012) 1.58
Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif. Genome Res (2008) 1.58
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proc Natl Acad Sci U S A (2011) 1.56
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. Proc Natl Acad Sci U S A (2011) 1.54
Coordination of erythropoiesis by the transcription factor c-Myb. Blood (2006) 1.52
Functions of BET proteins in erythroid gene expression. Blood (2015) 1.50
Tissue-specific splicing factor gene expression signatures. Nucleic Acids Res (2008) 1.49
Nuclear Condensation during Mouse Erythropoiesis Requires Caspase-3-Mediated Nuclear Opening. Dev Cell (2016) 1.49
The exosome complex establishes a barricade to erythroid maturation. Blood (2014) 1.48
RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development. J Exp Med (2014) 1.42
LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. Dev Cell (2009) 1.39
Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development. Mol Cell Biol (2008) 1.36
Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood (2012) 1.35
Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation. Mol Cell Biol (2007) 1.34
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood (2014) 1.34
Multilayered specification of the T-cell lineage fate. Immunol Rev (2010) 1.32
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220. Proc Natl Acad Sci U S A (2006) 1.30
Transcription factor networks in erythroid cell and megakaryocyte development. Blood (2011) 1.29
Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood (2009) 1.28
Alternative pre-mRNA splicing switches modulate gene expression in late erythropoiesis. Blood (2009) 1.25
Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins. Blood (2006) 1.25
Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis. Mol Cell Biol (2008) 1.23
Friend of GATA-1-independent transcriptional repression: a novel mode of GATA-1 function. Blood (2007) 1.21
EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2. J Biol Chem (2009) 1.13
Autophagy driven by a master regulator of hematopoiesis. Mol Cell Biol (2011) 1.13
SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. J Exp Med (2010) 1.10
FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood (2010) 1.09
Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor. Mol Cell (2009) 1.09
Differential sensitivities of transcription factor target genes underlie cell type-specific gene expression profiles. Proc Natl Acad Sci U S A (2006) 1.07
Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation. Blood (2008) 1.06
The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood (2009) 1.05
Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation. Blood (2013) 1.05
GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1. Mol Cell Biol (2005) 1.05
Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. J Biol Chem (2010) 1.04
A requirement for Lim domain binding protein 1 in erythropoiesis. J Exp Med (2010) 1.03
Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors. Cell Stem Cell (2013) 1.01
Relocalizing genetic loci into specific subnuclear neighborhoods. J Biol Chem (2011) 0.99
EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation. Mol Cell Biol (2010) 0.97
Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. Mol Cell Biol (2011) 0.97
Functional interaction of CP2 with GATA-1 in the regulation of erythroid promoters. Mol Cell Biol (2006) 0.97
GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription. Mol Cell Biol (2007) 0.97
Common themes emerge in the transcriptional control of T helper and developmental cell fate decisions regulated by the T-box, GATA and ROR families. Immunology (2009) 0.97
Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch. Biophys J (2008) 0.97
GATA-1 associates with and inhibits p53. Blood (2009) 0.96
Building multifunctionality into a complex containing master regulators of hematopoiesis. Proc Natl Acad Sci U S A (2010) 0.96
Multipotential differentiation ability of GATA-1-null erythroid-committed cells. Genes Dev (2006) 0.96
Erythro-megakaryocytic transcription factors associated with hereditary anemia. Blood (2014) 0.95
Haem-regulated eIF2alpha kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency. Br J Haematol (2008) 0.95
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53. Blood (2012) 0.93
Functional regulation of pre-B-cell leukemia homeobox interacting protein 1 (PBXIP1/HPIP) in erythroid differentiation. J Biol Chem (2011) 0.93
Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes. Mol Cell Biol (2010) 0.93
Role of STAT3 and GATA-1 interactions in gamma-globin gene expression. Exp Hematol (2009) 0.93
Trim58 degrades Dynein and regulates terminal erythropoiesis. Dev Cell (2014) 0.93
Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. Dev Cell (2016) 0.92
The hematopoietic regulator TAL1 is required for chromatin looping between the β-globin LCR and human γ-globin genes to activate transcription. Nucleic Acids Res (2014) 0.92
Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis. Genome Res (2014) 0.92
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Galaxy: a platform for interactive large-scale genome analysis. Genome Res (2005) 35.75
Human-mouse alignments with BLASTZ. Genome Res (2003) 35.49
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
The B73 maize genome: complexity, diversity, and dynamics. Science (2009) 18.73
The accessible chromatin landscape of the human genome. Nature (2012) 16.86
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Systematic localization of common disease-associated variation in regulatory DNA. Science (2012) 14.47
BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell (2011) 14.34
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. N Engl J Med (2015) 13.08
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. N Engl J Med (2014) 12.29
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature (2011) 11.44
Complete Khoisan and Bantu genomes from southern Africa. Nature (2010) 9.06
Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell (2013) 8.37
Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med (2014) 8.36
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol (2003) 8.12
An expansive human regulatory lexicon encoded in transcription factor footprints. Nature (2012) 7.27
Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences. Genome Res (2005) 7.09
28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Res (2007) 6.42
A framework for collaborative analysis of ENCODE data: making large-scale analyses biologist-friendly. Genome Res (2007) 5.97
Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell (2005) 5.96
The genome of woodland strawberry (Fragaria vesca). Nat Genet (2010) 5.86
The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell (2005) 5.81
Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Mol Cell (2005) 5.77
Distinguishing regulatory DNA from neutral sites. Genome Res (2003) 5.63
Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol (2006) 5.01
MultiPipMaker and supporting tools: Alignments and analysis of multiple genomic DNA sequences. Nucleic Acids Res (2003) 4.97
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nat Cell Biol (2007) 4.67
DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol (2008) 4.56
Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. AJNR Am J Neuroradiol (2003) 4.44
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis. Cancer Cell (2002) 4.36
zPicture: dynamic alignment and visualization tool for analyzing conservation profiles. Genome Res (2004) 4.26
An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol (2012) 4.15
Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature (2013) 3.98
Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene. J Biol Chem (2003) 3.93
Cross-species sequence comparisons: a review of methods and available resources. Genome Res (2003) 3.90
LTR_FINDER: an efficient tool for the prediction of full-length LTR retrotransposons. Nucleic Acids Res (2007) 3.89
Integrative annotation of chromatin elements from ENCODE data. Nucleic Acids Res (2012) 3.80
The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. Genes Dev (2003) 3.79
Integrated pipeline for mass spectrometry-based discovery and confirmation of biomarkers demonstrated in a mouse model of breast cancer. J Proteome Res (2007) 3.48
Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A (2014) 3.35
GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proc Natl Acad Sci U S A (2003) 3.32
Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol (2003) 3.27
Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus. Mol Cell (2008) 3.24
Reference genome sequence of the model plant Setaria. Nat Biotechnol (2012) 3.21
Complete response to neoadjuvant chemoradiotherapy in esophageal carcinoma is associated with significantly improved survival. J Clin Oncol (2005) 3.12
A GATA-1-regulated microRNA locus essential for erythropoiesis. Proc Natl Acad Sci U S A (2008) 3.10
A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus. Mol Cell Biol (2003) 3.09
Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol Cell (2009) 3.05
A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology. FASEB J (2002) 3.05
Mitoferrin is essential for erythroid iron assimilation. Nature (2006) 2.99
De novo genome sequencing and comparative genomics of date palm (Phoenix dactylifera). Nat Biotechnol (2011) 2.94
Evolution and functional classification of vertebrate gene deserts. Genome Res (2004) 2.92
A targeted proteomics-based pipeline for verification of biomarkers in plasma. Nat Biotechnol (2011) 2.91
Mulan: multiple-sequence local alignment and visualization for studying function and evolution. Genome Res (2004) 2.91
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest (2011) 2.90
Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nat Immunol (2002) 2.87
Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell (2012) 2.87
A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell (2012) 2.81
Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res (2013) 2.81
mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging. Cell Stem Cell (2009) 2.74
Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev (2009) 2.70
ESPERR: learning strong and weak signals in genomic sequence alignments to identify functional elements. Genome Res (2006) 2.65
Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res (2009) 2.64
Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2. EMBO J (2004) 2.62
GALA, a database for genomic sequence alignments and annotations. Genome Res (2003) 2.56
Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Mol Cell Biol (2006) 2.56
The genome of the pear (Pyrus bretschneideri Rehd.). Genome Res (2012) 2.55
FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. EMBO J (2005) 2.53
GATA-1-mediated proliferation arrest during erythroid maturation. Mol Cell Biol (2003) 2.52
Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach. Nat Genet (2011) 2.51
In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. Biotechniques (2006) 2.46
What fraction of the human genome is functional? Genome Res (2011) 2.46
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes Dev (2011) 2.38
Diaqua-bis(5-carb-oxy-2-propyl-1H-imidazole-4-carboxyl-ato-κN,O)manganese(II) N,N-dimethyl-formamide disolvate. Acta Crystallogr Sect E Struct Rep Online (2009) 2.35
Current advances in research and clinical applications of PLGA-based nanotechnology. Expert Rev Mol Diagn (2009) 2.35
An abundant erythroid protein that stabilizes free alpha-haemoglobin. Nature (2002) 2.33
Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis. World J Surg (2009) 2.31
Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes Dev (2003) 2.27
Low expression of microRNA-126 is associated with poor prognosis in colorectal cancer. Genes Chromosomes Cancer (2014) 2.24
Improvements in the HbVar database of human hemoglobin variants and thalassemia mutations for population and sequence variation studies. Nucleic Acids Res (2004) 2.24
HbVar database of human hemoglobin variants and thalassemia mutations: 2007 update. Hum Mutat (2007) 2.22
Registry and survival study in chinese patients with idiopathic and familial pulmonary arterial hypertension. Chest (2007) 2.19
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood (2008) 2.19