Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes.

PubWeight™: 1.84‹?› | Rank: Top 3%

🔗 View Article (PMC 2169421)

Published in Mol Cell Biol on October 08, 2007

Authors

Gregory D Gregory1, Christopher R Vakoc, Tanya Rozovskaia, Xingwu Zheng, Shetal Patel, Tatsuya Nakamura, Eli Canaani, Gerd A Blobel

Author Affiliations

1: Children's Hospital of Philadelphia, Division of Hematology, Philadelphia, Pennsylvania 19104, USA.

Articles citing this

De novo gene disruptions in children on the autistic spectrum. Neuron (2012) 9.69

Histone recognition and large-scale structural analysis of the human bromodomain family. Cell (2012) 5.15

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol (2008) 4.56

Targeting bromodomains: epigenetic readers of lysine acetylation. Nat Rev Drug Discov (2014) 3.54

Understanding the language of Lys36 methylation at histone H3. Nat Rev Mol Cell Biol (2012) 3.52

Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Mol Cell Biol (2009) 3.26

H3K36 methylation antagonizes PRC2-mediated H3K27 methylation. J Biol Chem (2011) 2.63

The molecular biology of mixed lineage leukemia. Haematologica (2009) 2.58

Bromodomains as therapeutic targets. Expert Rev Mol Med (2011) 2.52

A long ncRNA links copy number variation to a polycomb/trithorax epigenetic switch in FSHD muscular dystrophy. Cell (2012) 2.29

Histone H3 lysine 4 (H3K4) methylation in development and differentiation. Dev Biol (2009) 2.24

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate. J Biol Chem (2009) 2.06

A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Mol Cell (2009) 1.94

Drosophila Kismet regulates histone H3 lysine 27 methylation and early elongation by RNA polymerase II. PLoS Genet (2008) 1.75

MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis. PLoS Genet (2015) 1.49

Epigenetic modifications in plants: an evolutionary perspective. Curr Opin Plant Biol (2011) 1.45

Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism. J Biol Chem (2011) 1.30

Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity. Cold Spring Harb Perspect Biol (2009) 1.09

Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes. RNA Biol (2009) 1.07

Histone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells. Cell Biosci (2013) 1.07

CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin. FEBS J (2009) 1.01

Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells. J Clin Invest (2015) 1.00

Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation. Hepatology (2012) 0.95

Histone target selection within chromatin: an exemplary case of teamwork. Genes Dev (2014) 0.95

The role of the double bromodomain-containing BET genes during mammalian spermatogenesis. Curr Top Dev Biol (2013) 0.92

The long non-coding RNA Fendrr links epigenetic control mechanisms to gene regulatory networks in mammalian embryogenesis. RNA Biol (2013) 0.92

Photoreceptor phagocytosis is mediated by phosphoinositide signaling. FASEB J (2013) 0.91

The quest for mammalian Polycomb response elements: are we there yet? Chromosoma (2015) 0.91

Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing. PLoS Genet (2013) 0.90

Previous history of chronic stress changes the transcriptional response to glucocorticoid challenge in the dentate gyrus region of the male rat hippocampus. Endocrinology (2013) 0.90

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer. Oncotarget (2015) 0.90

The trithorax group proteins Kismet and ASH1 promote H3K36 dimethylation to counteract Polycomb group repression in Drosophila. Development (2013) 0.87

Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation. EMBO J (2008) 0.86

Facioscapulohumeral muscular dystrophy as a model for epigenetic regulation and disease. Antioxid Redox Signal (2014) 0.86

Stable transmission of reversible modifications: maintenance of epigenetic information through the cell cycle. Cell Mol Life Sci (2010) 0.86

On your histone mark, SET, methylate! Epigenetics (2013) 0.85

Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation. G3 (Bethesda) (2013) 0.82

NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters. PLoS One (2011) 0.81

Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS One (2014) 0.81

The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila. Genome Biol (2013) 0.79

Phenotypic and molecular evaluation of a chromosome 1q region with linkage and association to type 2 diabetes in humans. J Clin Endocrinol Metab (2009) 0.79

CpG islands under selective pressure are enriched with H3K4me3, H3K27ac and H3K36me3 histone modifications. BMC Evol Biol (2013) 0.78

Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers. Int J Epidemiol (2015) 0.78

Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase. Biochemistry (2015) 0.77

Status of epigenetic chromatin modification enzymes and esophageal squamous cell carcinoma risk in northeast Indian population. Am J Cancer Res (2015) 0.76

Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α. Sci Rep (2016) 0.76

Increased Set1 binding at the promoter induces aberrant epigenetic alterations and up-regulates cyclic adenosine 5'-monophosphate response element modulator alpha in systemic lupus erythematosus. Clin Epigenetics (2016) 0.75

The Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in Mice. Biol Reprod (2015) 0.75

The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice. Sci Rep (2017) 0.75

Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy. Oncotarget (2015) 0.75

Role of several histone lysine methyltransferases in tumor development. Biomed Rep (2016) 0.75

Role of p53, Mitochondrial DNA Deletions, and Paternal Age in Autism: A Case-Control Study. Pediatrics (2016) 0.75

An Ash1-Like Protein MoKMT2H Null Mutant Is Delayed for Conidium Germination and Pathogenesis in Magnaporthe oryzae. Biomed Res Int (2016) 0.75

Articles cited by this

High-resolution profiling of histone methylations in the human genome. Cell (2007) 85.74

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18

Chromatin modifications and their function. Cell (2007) 55.98

The epigenomics of cancer. Cell (2007) 30.91

The role of chromatin during transcription. Cell (2007) 26.48

Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A (2002) 25.47

Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature (2000) 18.26

Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity. Mol Cell (2003) 11.78

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature (2006) 10.73

Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nat Cell Biol (2003) 8.82

Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem (2006) 8.66

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature (2002) 7.54

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell (2003) 7.47

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol Cell (2004) 6.90

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation. Mol Cell (2002) 6.72

Altered Hox expression and segmental identity in Mll-mutant mice. Nature (1995) 6.60

Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains. Mol Cell (2003) 6.44

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell (2005) 6.12

Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol (2006) 6.03

Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell (2005) 5.96

Regulation of p53 activity through lysine methylation. Nature (2004) 5.78

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth. Mol Cell Biol (2006) 5.74

Global and Hox-specific roles for the MLL1 methyltransferase. Proc Natl Acad Sci U S A (2005) 5.53

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell (1992) 5.39

The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J (2001) 5.34

Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. Mol Cell (2001) 5.04

Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins. Genes Dev (2006) 5.03

Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol (2006) 5.01

Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes. J Biol Chem (2005) 4.78

Repression of p53 activity by Smyd2-mediated methylation. Nature (2006) 4.51

Global regulation of erythroid gene expression by transcription factor GATA-1. Blood (2004) 4.22

Retracted Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1. Nature (2002) 4.18

Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. Mol Cell Biol (1997) 4.12

Retracted Noncoding RNAs of trithorax response elements recruit Drosophila Ash1 to Ultrabithorax. Science (2006) 4.10

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol Cell (2005) 4.04

A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. Mol Cell Biol (2005) 3.79

Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference. Cell (2006) 3.76

Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. PLoS Genet (2007) 3.75

Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes. Nat Struct Mol Biol (2006) 3.54

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development. Development (2006) 3.28

The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes. Development (1998) 3.06

mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Mol Cell (2003) 2.97

MLL associates specifically with a subset of transcriptionally active target genes. Proc Natl Acad Sci U S A (2005) 2.87

The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains. Proc Natl Acad Sci U S A (1990) 2.85

The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. Mol Cell (2005) 2.79

The human PAF complex coordinates transcription with events downstream of RNA synthesis. Genes Dev (2005) 2.70

Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences. Mol Cell Biol (2006) 2.68

MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci U S A (1998) 2.65

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation. Genes Dev (2003) 2.65

Gene-specific modulation of TAF10 function by SET9-mediated methylation. Mol Cell (2004) 2.56

In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. Biotechniques (2006) 2.46

BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. Curr Biol (2005) 2.32

Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1. Mol Cell (2005) 2.32

The Drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head. Genes Dev (1994) 2.22

Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases. Proc Natl Acad Sci U S A (2006) 2.16

Gene-specific targeting of H3K9 methylation is sufficient for initiating repression in vivo. Curr Biol (2002) 1.90

ASH1, a Drosophila trithorax group protein, is required for methylation of lysine 4 residues on histone H3. Proc Natl Acad Sci U S A (2003) 1.84

Highly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain. Mol Cell Biol (2003) 1.66

Trithorax-group protein ASH1 methylates histone H3 lysine 36. Gene (2007) 1.56

Leaving a mark: the many footprints of the elongating RNA polymerase II. Curr Opin Genet Dev (2006) 1.46

Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment. Mol Genet Genomics (2006) 1.42

Molecular genetic analysis of the Drosophila melanogaster gene absent, small or homeotic discs1 (ash1). Genetics (1994) 1.40

Trithorax and ASH1 interact directly and associate with the trithorax group-responsive bxd region of the Ultrabithorax promoter. Mol Cell Biol (1999) 1.38

Methods and tips for the purification of human histone methyltransferases. Methods (2003) 1.31

huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions. Proc Natl Acad Sci U S A (2000) 1.05

Articles by these authors

BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell (2011) 14.34

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature (2011) 11.44

Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell (2013) 8.37

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature (2007) 8.32

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation. Mol Cell (2002) 6.72

A histone H3 lysine 27 demethylase regulates animal posterior development. Nature (2007) 6.57

Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell (2005) 5.96

Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Mol Cell (2005) 5.77

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth. Mol Cell Biol (2006) 5.74

Global and Hox-specific roles for the MLL1 methyltransferase. Proc Natl Acad Sci U S A (2005) 5.53

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. Blood (2008) 5.23

Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol (2006) 5.01

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol (2008) 4.56

Global regulation of erythroid gene expression by transcription factor GATA-1. Blood (2004) 4.22

An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol (2012) 4.15

Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature (2013) 3.98

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. J Clin Invest (2006) 3.27

Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus. Mol Cell (2008) 3.24

Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. JAMA (2011) 3.16

Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell (2012) 2.87

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming. Nature (2012) 2.80

Modulation of heat shock gene expression by the TAC1 chromatin-modifying complex. Nat Cell Biol (2004) 2.79

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res (2009) 2.64

Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2. EMBO J (2004) 2.62

FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. EMBO J (2005) 2.53

GATA-1-mediated proliferation arrest during erythroid maturation. Mol Cell Biol (2003) 2.52

In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. Biotechniques (2006) 2.46

TrxG and PcG proteins but not methylated histones remain associated with DNA through replication. Cell (2012) 2.45

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia. Genes Dev (2008) 2.41

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes Dev (2011) 2.38

An abundant erythroid protein that stabilizes free alpha-haemoglobin. Nature (2002) 2.33

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood (2008) 2.19

The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. Mol Cell Biol (2004) 2.13

Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1. Mol Cell Biol (2003) 2.09

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes Dev (2013) 2.07

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Res (2011) 2.07

Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration. Science (2003) 2.02

Context-dependent regulation of GATA-1 by friend of GATA-1. Proc Natl Acad Sci U S A (2003) 2.01

A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit. Mol Cell (2009) 1.94

MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer. J Natl Cancer Inst (2010) 1.94

Distinct functions of dispersed GATA factor complexes at an endogenous gene locus. Mol Cell Biol (2006) 1.94

Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain. Proc Natl Acad Sci U S A (2002) 1.91

GATA Transcription Factors and Cancer. Genes Cancer (2010) 1.88

Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors. EMBO J (2002) 1.84

Analysis of perpetrator admissions to inflicted traumatic brain injury in children. Arch Pediatr Adolesc Med (2004) 1.77

Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell (2012) 1.74

A motif within SET-domain proteins binds single-stranded nucleic acids and transcribed and supercoiled DNAs and can interfere with assembly of nucleosomes. Mol Cell Biol (2005) 1.71

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. EMBO J (2009) 1.66

Differentiation of noncancerous tissue and cancer lesions by apparent diffusion coefficient values in transition and peripheral zones of the prostate. J Magn Reson Imaging (2005) 1.61

Room-temperature miscibility gap in LixFePO4. Nat Mater (2006) 1.58

Chromatin loops in gene regulation. Biochim Biophys Acta (2008) 1.57

Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila. Nature (2003) 1.57

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Proc Natl Acad Sci U S A (2011) 1.56

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML. Oncotarget (2012) 1.50

Mitotic bookmarking by transcription factors. Epigenetics Chromatin (2013) 1.38

Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation. Mol Cell Biol (2007) 1.34

Lnk constrains myeloproliferative diseases in mice. J Clin Invest (2010) 1.29

Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood (2009) 1.28

Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood (2007) 1.28

Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing. Proc Natl Acad Sci U S A (2007) 1.27

Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins. Blood (2006) 1.25

Metallo-beta-lactamase-producing gram-negative bacilli: laboratory-based surveillance in cooperation with 13 clinical laboratories in the Kinki region of Japan. J Clin Microbiol (2004) 1.25

Acetylation of GATA-1 is required for chromatin occupancy. Blood (2006) 1.19

E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells. J Biol Chem (2004) 1.17

Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia. Proc Natl Acad Sci U S A (2013) 1.17

High prevalence of CTX-M beta-lactamase-producing Enterobacteriaceae in stool specimens obtained from healthy individuals in Thailand. J Antimicrob Chemother (2010) 1.13

Do chromatin loops provide epigenetic gene expression states? Curr Opin Genet Dev (2010) 1.12

Regulation of BRCA1 transcription by specific single-stranded DNA binding factors. Mol Cell Biol (2003) 1.10

FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood (2010) 1.09

Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Mol Cell Biol (2011) 1.08

The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex. J Mol Cell Cardiol (2007) 1.08

Computer-aided diagnosis: a shape classification of pulmonary nodules imaged by high-resolution CT. Comput Med Imaging Graph (2005) 1.06

IRF4 mutations in chronic lymphocytic leukemia. Blood (2011) 1.05

Diffusion-weighted images of the liver: comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide. J Magn Reson Imaging (2005) 1.04

Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. J Biol Chem (2010) 1.04

Initial observations on the effect of irradiation on the liver-specific uptake of Levovist. Eur J Radiol (2002) 1.04

Comparison of flow artifacts between 2D-FLAIR and 3D-FLAIR sequences at 3 T. Eur Radiol (2004) 1.03

Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1. Mol Cell Biol (2002) 1.03

Contralateral and ipsilateral responses in primary somatosensory cortex following electrical median nerve stimulation--an fMRI study. Clin Neurophysiol (2004) 1.01

WRAD: enabler of the SET1-family of H3K4 methyltransferases. Brief Funct Genomics (2012) 1.01

Aichi cancer center initial experience of intensity modulated radiation therapy for nasopharyngeal cancer using helical tomotherapy. Int J Radiat Oncol Biol Phys (2008) 1.01

Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions. J Biol Chem (2008) 1.00

Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation. Proc Natl Acad Sci U S A (2011) 1.00