Published in Mol Microbiol on March 01, 2007
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Candida albicans pathogenicity mechanisms. Virulence (2013) 2.60
Sub-telomere directed gene expression during initiation of invasive aspergillosis. PLoS Pathog (2008) 2.09
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog (2008) 1.94
Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiol Mol Biol Rev (2011) 1.90
Self-regulation of Candida albicans population size during GI colonization. PLoS Pathog (2007) 1.85
Glucose promotes stress resistance in the fungal pathogen Candida albicans. Mol Biol Cell (2009) 1.52
Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection. Mol Microbiol (2008) 1.49
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections. Infect Immun (2009) 1.48
Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney. Fungal Genet Biol (2008) 1.37
An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells. Front Microbiol (2012) 1.35
Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS Pathog (2012) 1.34
Adaptations of Candida albicans for growth in the mammalian intestinal tract. Eukaryot Cell (2010) 1.32
Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo. Eukaryot Cell (2012) 1.30
Nitrosative and oxidative stress responses in fungal pathogenicity. Curr Opin Microbiol (2009) 1.28
Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1. PLoS Pathog (2013) 1.27
Stress adaptation in a pathogenic fungus. J Exp Biol (2014) 1.21
Intracellular acetyl unit transport in fungal carbon metabolism. Eukaryot Cell (2010) 1.18
Aneuploid chromosomes are highly unstable during DNA transformation of Candida albicans. Eukaryot Cell (2009) 1.15
Zebrafish as a model host for Candida albicans infection. Infect Immun (2010) 1.12
Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans. Proc Natl Acad Sci U S A (2011) 1.11
Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis. Infect Immun (2010) 1.09
The evolutionary rewiring of ubiquitination targets has reprogrammed the regulation of carbon assimilation in the pathogenic yeast Candida albicans. MBio (2012) 1.08
Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes. Eukaryot Cell (2012) 1.06
Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells. Infect Immun (2012) 1.06
Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model. Eukaryot Cell (2009) 1.05
Massive induction of innate immune response to Candida albicans in the kidney in a murine intravenous challenge model. FEMS Yeast Res (2009) 1.04
Carbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans. Proteomics (2012) 1.02
Oxidative stress responses in the human fungal pathogen, Candida albicans. Biomolecules (2015) 0.99
Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels. Trends Microbiol (2014) 0.98
Niche-specific gene expression during C. albicans infection. Curr Opin Microbiol (2008) 0.97
Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia. PLoS Pathog (2010) 0.96
The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor. PLoS Pathog (2012) 0.95
Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans. Mol Microbiol (2011) 0.95
Dynamic transcript profiling of Candida albicans infection in zebrafish: a pathogen-host interaction study. PLoS One (2013) 0.94
In vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization. PLoS One (2011) 0.93
Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans. PLoS One (2012) 0.93
pH Response Pathways in Fungi: Adapting to Host-derived and Environmental Signals. Mycobiology (2011) 0.93
Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape. Antioxid Redox Signal (2013) 0.92
The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection. Virulence (2013) 0.90
Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections. PLoS One (2011) 0.88
MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans. J Biol Chem (2011) 0.86
RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens In Vivo Applied to the Fungus Candida albicans. MBio (2015) 0.86
Nitric oxide and nitrosative stress tolerance in yeast. Biochem Soc Trans (2011) 0.86
Metabolism in fungal pathogenesis. Cold Spring Harb Perspect Med (2014) 0.86
Essential metals at the host-pathogen interface: nutritional immunity and micronutrient assimilation by human fungal pathogens. FEMS Yeast Res (2015) 0.85
Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans. BMC Microbiol (2008) 0.85
Protein kinase A and fungal virulence: a sinister side to a conserved nutrient sensing pathway. Virulence (2012) 0.83
pH signaling in human fungal pathogens: a new target for antifungal strategies. Eukaryot Cell (2014) 0.82
Morphogenic and genetic differences between Candida albicans strains are associated with keratomycosis virulence. Mol Vis (2009) 0.82
Distinct roles of Candida albicans-specific genes in host-pathogen interactions. Eukaryot Cell (2014) 0.82
The heat-induced molecular disaggregase Hsp104 of Candida albicans plays a role in biofilm formation and pathogenicity in a worm infection model. Eukaryot Cell (2012) 0.81
Studies of Immune Responses in Candida vaginitis. Pathogens (2015) 0.81
Involvement of the mitogen activated protein kinase Hog1p in the response of Candida albicans to iron availability. BMC Microbiol (2013) 0.81
Transcriptional profiling of Candida glabrata during phagocytosis by neutrophils and in the infected mouse spleen. Infect Immun (2013) 0.80
Immunosensing during colonization by Candida albicans: does it take a village to colonize the intestine? Trends Microbiol (2011) 0.79
Functional characterization of the small heat shock protein Hsp12p from Candida albicans. PLoS One (2012) 0.79
β-1,2-Mannosyltransferases 1 and 3 Participate in Yeast and Hyphae O- and N-Linked Mannosylation and Alter Candida albicans Fitness During Infection. Open Forum Infect Dis (2015) 0.78
Hsp21 potentiates antifungal drug tolerance in Candida albicans. PLoS One (2013) 0.77
Isolation of Blastomyces dermatitidis yeast from lung tissue during murine infection for in vivo transcriptional profiling. Fungal Genet Biol (2013) 0.77
Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis. Mol Biol Cell (2016) 0.77
In Vivo Transcriptional Profiling of Human Pathogenic Fungi during Infection: Reflecting the Real Life? PLoS Pathog (2016) 0.76
Novel Approaches for Fungal Transcriptomics from Host Samples. Front Microbiol (2016) 0.75
Host pathogen relations: exploring animal models for fungal pathogens. Pathogens (2014) 0.75
Dictyostelium discoideum as a Novel Host System to Study the Interaction between Phagocytes and Yeasts. Front Microbiol (2016) 0.75
The game theory of Candida albicans colonization dynamics reveals host status-responsive gene expression. BMC Syst Biol (2016) 0.75
Transcriptional Profiling of Candida albicans in the Host. Methods Mol Biol (2016) 0.75
Phosphate Acquisition and Virulence in Human Fungal Pathogens. Microorganisms (2017) 0.75
Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis (2009) 18.19
Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus. N Engl J Med (2006) 8.20
Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature (2009) 5.90
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med (2009) 5.55
Guidelines for treatment of candidiasis. Clin Infect Dis (2003) 5.55
T-helper-1-cell cytokines drive cancer into senescence. Nature (2013) 4.47
Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol Rev (2003) 4.07
Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo. PLoS Pathog (2006) 3.58
Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. PLoS Biol (2007) 3.43
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biol Chem (2005) 3.02
Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway. Mol Microbiol (2002) 3.01
Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood. Mol Microbiol (2005) 3.00
Functional and structural diversity in the Als protein family of Candida albicans. J Biol Chem (2004) 2.77
Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis. Genetics (2002) 2.71
Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis. Clin Infect Dis (2008) 2.63
Candida albicans pathogenicity mechanisms. Virulence (2013) 2.60
A phase II randomized trial of amphotericin B alone or combined with fluconazole in the treatment of HIV-associated cryptococcal meningitis. Clin Infect Dis (2009) 2.53
Mice with disseminated candidiasis die of progressive sepsis. J Infect Dis (2005) 2.42
Complementary adhesin function in C. albicans biofilm formation. Curr Biol (2008) 2.41
In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol (2007) 2.35
Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1. Nature (2011) 2.31
Current treatment strategies for disseminated candidiasis. Clin Infect Dis (2005) 2.25
Novel inhalational murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother (2004) 2.23
Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis. Cell Microbiol (2005) 2.15
Calcineurin is essential for Candida albicans survival in serum and virulence. Eukaryot Cell (2003) 1.98
Stage-specific gene expression of Candida albicans in human blood. Mol Microbiol (2003) 1.97
Hydrolytic enzymes as virulence factors of Candida albicans. Mycoses (2005) 1.96
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog (2008) 1.94
The siderophore iron transporter of Candida albicans (Sit1p/Arn1p) mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion. Infect Immun (2002) 1.91
Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging. J Exp Med (2010) 1.86
Bartonella adhesin a mediates a proangiogenic host cell response. J Exp Med (2004) 1.84
Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs. Infect Immun (2002) 1.82
EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection. Proc Natl Acad Sci U S A (2012) 1.81
Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis. Infect Immun (2003) 1.78
The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus. Infect Immun (2008) 1.77
Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes. Cell Microbiol (2009) 1.77
Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions. J Biol Chem (2005) 1.77
NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus, is safe and immunogenic in healthy adults. Vaccine (2012) 1.77
Candida albicans transcription factor Rim101 mediates pathogenic interactions through cell wall functions. Cell Microbiol (2008) 1.76
Candida albicans proteinases and host/pathogen interactions. Cell Microbiol (2004) 1.73
Anti-fungal therapy at the HAART of viral therapy. Trends Microbiol (2002) 1.72
Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J Clin Invest (2007) 1.67
Human defensins. J Mol Med (Berl) (2005) 1.66
Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis. J Infect Dis (2006) 1.64
Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence. J Infect Dis (2008) 1.64
Cryptococcal immune reconstitution inflammatory syndrome after antiretroviral therapy in AIDS patients with cryptococcal meningitis: a prospective multicenter study. Clin Infect Dis (2009) 1.63
Interleukin 23 expression in pyoderma gangrenosum and targeted therapy with ustekinumab. Arch Dermatol (2011) 1.62
Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro. Infect Immun (2004) 1.59
A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans. Eukaryot Cell (2002) 1.56
Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity. Blood (2003) 1.56
A randomized study of the use of fluconazole in continuous versus episodic therapy in patients with advanced HIV infection and a history of oropharyngeal candidiasis: AIDS Clinical Trials Group Study 323/Mycoses Study Group Study 40. Clin Infect Dis (2005) 1.56
From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One (2011) 1.54
The anti-Candida albicans vaccine composed of the recombinant N terminus of Als1p reduces fungal burden and improves survival in both immunocompetent and immunocompromised mice. Infect Immun (2005) 1.53
Candida albicans Als3, a multifunctional adhesin and invasin. Eukaryot Cell (2010) 1.52
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology (2008) 1.52
Importance of the Candida albicans cell wall during commensalism and infection. Curr Opin Microbiol (2012) 1.50
Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs. Eur J Immunol (2012) 1.50
Functional analysis of the Candida albicans ALS1 gene product. Yeast (2004) 1.50
The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium. Infect Immun (2003) 1.49
Requirement for Candida albicans Sun41 in biofilm formation and virulence. Eukaryot Cell (2007) 1.46
Interactions of Candida albicans with epithelial cells. Cell Microbiol (2009) 1.45
Host cell invasion and virulence mediated by Candida albicans Ssa1. PLoS Pathog (2010) 1.43
Mouse model of oropharyngeal candidiasis. Nat Protoc (2012) 1.40
Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape. Curr Opin Microbiol (2010) 1.39
N-cadherin mediates endocytosis of Candida albicans by endothelial cells. J Biol Chem (2005) 1.36
Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity. Infect Immun (2005) 1.35
An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells. Front Microbiol (2012) 1.35
Candida albicans iron acquisition within the host. FEMS Yeast Res (2009) 1.35
Candida albicans dimorphism as a therapeutic target. Expert Rev Anti Infect Ther (2012) 1.34
The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice. J Clin Invest (2010) 1.34
Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol (2011) 1.34
Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS Pathog (2012) 1.34
Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc (2006) 1.34
The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation. J Immunol (2011) 1.33
Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene. Mol Microbiol (2002) 1.31
The Aspergillus fumigatus StuA protein governs the up-regulation of a discrete transcriptional program during the acquisition of developmental competence. Mol Biol Cell (2005) 1.31
Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis. Infect Immun (2002) 1.30
Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo. Eukaryot Cell (2012) 1.30
Toll-like receptors as key mediators in innate antifungal immunity. Med Mycol (2004) 1.29
Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis. Microbiology (2004) 1.29
Infection of human oral epithelia with Candida species induces cytokine expression correlated to the degree of virulence. J Invest Dermatol (2002) 1.27
Skin commensals amplify the innate immune response to pathogens by activation of distinct signaling pathways. J Invest Dermatol (2010) 1.26
β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance. PLoS One (2011) 1.25
Genetic basis for differential activities of fluconazole and voriconazole against Candida krusei. Antimicrob Agents Chemother (2003) 1.25
Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism. Cell Microbiol (2009) 1.24
Standardization of an experimental murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother (2006) 1.24
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction. Autophagy (2011) 1.24
Polymorphonuclear leukocytes (PMNs) induce protective Th1-type cytokine epithelial responses in an in vitro model of oral candidosis. Microbiology (2004) 1.23
Candida albicans protein kinase CK2 governs virulence during oropharyngeal candidiasis. Cell Microbiol (2006) 1.21
Expression analysis of the Candida albicans lipase gene family during experimental infections and in patient samples. FEMS Yeast Res (2004) 1.20