Published in J Neurosci on September 15, 2004
Apical constriction: a cell shape change that can drive morphogenesis. Dev Biol (2009) 2.90
The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harb Perspect Biol (2011) 2.22
Genetics and development of neural tube defects. J Pathol (2010) 2.10
Ena/VASP: towards resolving a pointed controversy at the barbed end. J Cell Sci (2009) 2.05
Neurulation in the cranial region--normal and abnormal. J Anat (2005) 1.47
Metastasis: tumor cells becoming MENAcing. Trends Cell Biol (2010) 1.44
N- and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements. Development (2009) 1.39
Ena/VASP: proteins at the tip of the nervous system. Curr Opin Neurobiol (2008) 1.37
c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis. Curr Biol (2010) 1.34
Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors. Breast Cancer Res (2010) 1.24
Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination. Development (2010) 1.15
VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis. J Cell Sci (2009) 1.13
Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesis. Dev Biol (2009) 1.10
Ena/VASP function in retinal axons is required for terminal arborization but not pathway navigation. Development (2007) 1.04
The assembly and maintenance of epithelial junctions in C. elegans. Front Biosci (Landmark Ed) (2009) 1.01
Mammalian enabled (Mena) is a critical regulator of cardiac function. Am J Physiol Heart Circ Physiol (2011) 0.94
Enabled (Xena) regulates neural plate morphogenesis, apical constriction, and cellular adhesion required for neural tube closure in Xenopus. Dev Biol (2007) 0.92
How to form and close the brain: insight into the mechanism of cranial neural tube closure in mammals. Cell Mol Life Sci (2012) 0.92
A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation. J Cell Sci (2009) 0.87
Epithelial fusion during neural tube morphogenesis. Birth Defects Res A Clin Mol Teratol (2012) 0.86
MENA is a transcriptional target of the Wnt/beta-catenin pathway. PLoS One (2012) 0.86
Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development. Development (2015) 0.84
Fat3 and Ena/VASP proteins influence the emergence of asymmetric cell morphology in the developing retina. Development (2016) 0.83
Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy. Cell Commun Signal (2013) 0.81
Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development (2015) 0.80
Selectivity in subunit composition of Ena/VASP tetramers. Biosci Rep (2015) 0.79
Regulation of cell protrusions by small GTPases during fusion of the neural folds. Elife (2016) 0.78
From morphogen to morphogenesis and back. Nature (2017) 0.77
Expression and Distribution Characteristics of Human Ortholog of Mammalian Enabled (hMena) in Glioma. Chin J Cancer Res (2011) 0.75
Identification and expression analysis of splice variants of mouse enabled homologue during development and in adult tissues. BMC Mol Biol (2010) 0.75
A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons. Neuron (2017) 0.75
CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex. J Cell Biol (2017) 0.75
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet (2003) 12.16
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med (2008) 9.05
Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell (2002) 6.80
Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron (2003) 5.19
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. Cell (2006) 4.43
Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration. Annu Rev Cell Dev Biol (2003) 4.22
Neuronal fate determinants of adult olfactory bulb neurogenesis. Nat Neurosci (2005) 3.67
Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1. Neuron (2004) 3.65
Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end. Cell (2004) 3.48
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia. Nature (2007) 3.46
Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm. Neuron (2003) 3.39
RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. Dev Cell (2004) 3.27
An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype. PLoS Genet (2011) 2.99
Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient. Cell (2008) 2.97
Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics. Dev Cell (2004) 2.96
Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins. J Biol Chem (2005) 2.88
Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron (2002) 2.77
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes Dev (2003) 2.68
A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis. Dev Cell (2008) 2.65
Filopodia are required for cortical neurite initiation. Nat Cell Biol (2007) 2.49
Filopodia: the fingers that do the walking. Sci STKE (2007) 2.43
Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination. Clin Cancer Res (2009) 2.41
Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation. J Cell Biol (2002) 2.34
Emergence of large-scale cell morphology and movement from local actin filament growth dynamics. PLoS Biol (2007) 2.30
Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function. Proc Natl Acad Sci U S A (2012) 2.29
Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev Cell (2010) 2.25
The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harb Perspect Biol (2011) 2.22
Arp2/3 is a negative regulator of growth cone translocation. Neuron (2004) 2.19
Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol (2009) 2.19
The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis. J Cell Biol (2002) 2.14
Ena/VASP proteins have an anti-capping independent function in filopodia formation. Mol Biol Cell (2007) 2.12
Ena/VASP: towards resolving a pointed controversy at the barbed end. J Cell Sci (2009) 2.05
Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron (2007) 2.01
Lifeact mice for studying F-actin dynamics. Nat Methods (2010) 2.00
Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer. J Cell Sci (2011) 2.00
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression. Nat Genet (2009) 1.99
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arterioscler Thromb Vasc Biol (2002) 1.97
Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contacts. Mol Biol Cell (2005) 1.93
Bidirectional regulation of hippocampal mossy fiber filopodial motility by kainate receptors: a two-step model of synaptogenesis. Neuron (2003) 1.93
The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells. Sci Signal (2013) 1.92
The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol (2003) 1.86
A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila. Proc Natl Acad Sci U S A (2003) 1.84
A role for the primary cilium in Notch signaling and epidermal differentiation during skin development. Cell (2011) 1.83
Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration. Mol Biol Cell (2002) 1.81
Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells. J Neurosci (2008) 1.81
Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell (2003) 1.81
The RGD motif in fibronectin is essential for development but dispensable for fibril assembly. J Cell Biol (2007) 1.81
A role for Nr-CAM in the patterning of binocular visual pathways. Neuron (2006) 1.79
Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). PLoS Biol (2009) 1.78
Enabled plays key roles in embryonic epithelial morphogenesis in Drosophila. Development (2007) 1.76
Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. J Biol Chem (2003) 1.72
Efficient transgenesis in farm animals by lentiviral vectors. EMBO Rep (2003) 1.72
Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist. Sci Signal (2013) 1.71
The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitors. Dev Cell (2007) 1.68
Integrins establish dendrite-substrate relationships that promote dendritic self-avoidance and patterning in drosophila sensory neurons. Neuron (2012) 1.67
A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Dev Biol (2007) 1.65
The stop signal revised: immature cerebellar granule neurons in the external germinal layer arrest pontine mossy fiber growth. J Neurosci (2006) 1.65
Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo. Clin Exp Metastasis (2008) 1.64
Association with the auxiliary subunit PEX5R/Trip8b controls responsiveness of HCN channels to cAMP and adrenergic stimulation. Neuron (2009) 1.64
Forward genetic analysis of visual behavior in zebrafish. PLoS Genet (2005) 1.62
MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin. Curr Biol (2006) 1.61
miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit. Nat Commun (2013) 1.59
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. J Exp Med (2009) 1.59
Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol (2008) 1.59
Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function. Diabetes (2010) 1.58
Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis. J Clin Invest (2007) 1.56
Function and regulation of Ena/VASP proteins. Trends Cell Biol (2003) 1.56
Ena/VASP is required for endothelial barrier function in vivo. J Cell Biol (2007) 1.53
Targeted disruption of the murine zyxin gene. Mol Cell Biol (2003) 1.51
Contribution of Ena/VASP proteins to intracellular motility of listeria requires phosphorylation and proline-rich core but not F-actin binding or multimerization. Mol Biol Cell (2002) 1.47
Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines. Clin Cancer Res (2008) 1.44
Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer. Proc Natl Acad Sci U S A (2008) 1.40
Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1. J Neurosci (2005) 1.40
Genetic modulation of BDNF signaling affects the outcome of axonal competition in vivo. Curr Biol (2007) 1.40
Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation. Nat Cell Biol (2011) 1.37
Ena/VASP: proteins at the tip of the nervous system. Curr Opin Neurobiol (2008) 1.37
Retinal axon growth at the optic chiasm: to cross or not to cross. Annu Rev Neurosci (2008) 1.36
Integrin signaling switches the cytoskeletal and exocytic machinery that drives neuritogenesis. Dev Cell (2010) 1.35
Palladin is a novel binding partner for Ena/VASP family members. Cell Motil Cytoskeleton (2004) 1.34
A high-throughput microfluidic assay to study neurite response to growth factor gradients. Lab Chip (2010) 1.33
Lineage tracing using matrilin-1 gene expression reveals that articular chondrocytes exist as the joint interzone forms. Dev Biol (2007) 1.30
Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina. J Neurosci (2002) 1.28
The Ena/VASP enigma. J Cell Sci (2002) 1.28
Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence. Mol Biol Cell (2008) 1.27
Tuba stimulates intracellular N-WASP-dependent actin assembly. J Cell Sci (2006) 1.26
Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion. Cancer Cell (2012) 1.26
2D protrusion but not motility predicts growth factor-induced cancer cell migration in 3D collagen. J Cell Biol (2012) 1.26
A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila. Nat Genet (2002) 1.25
Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes. J Cell Sci (2006) 1.24
Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration. J Cell Biol (2010) 1.24
Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis. Sci Signal (2009) 1.24
Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors. Breast Cancer Res (2010) 1.24
Epigenetic regulation of lentiviral transgene vectors in a large animal model. Mol Ther (2005) 1.23
PAR-3 mediates the initial clustering and apical localization of junction and polarity proteins during C. elegans intestinal epithelial cell polarization. Development (2010) 1.23
The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphology. Proc Natl Acad Sci U S A (2006) 1.23
Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM. Clin Exp Metastasis (2011) 1.23
Loss of alpha10beta1 integrin expression leads to moderate dysfunction of growth plate chondrocytes. J Cell Sci (2005) 1.22
The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides. J Biol Chem (2005) 1.21
Switching retinogeniculate axon laterality leads to normal targeting but abnormal eye-specific segregation that is activity dependent. J Neurosci (2009) 1.21