Published in Chest on December 01, 2004
Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol (2010) 2.20
Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. J Allergy Clin Immunol (2013) 1.80
Neutrophilic inflammation and IL-8 levels in induced sputum of alpha-1-antitrypsin PiMZ subjects. Thorax (2005) 1.01
Asthma in the elderly. Asia Pac Allergy (2012) 0.99
Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation. BMC Pulm Med (2013) 0.99
Airways disease: phenotyping heterogeneity using measures of airway inflammation. Allergy Asthma Clin Immunol (2007) 0.87
Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation. Respir Res (2015) 0.84
Influence of age, past smoking, and disease severity on TLR2, neutrophilic inflammation, and MMP-9 levels in COPD. Mediators Inflamm (2013) 0.83
Allergy and asthma in the elderly. Semin Respir Crit Care Med (2010) 0.82
Simplified detection of eosinophils in induced sputum. Inflamm Res (2011) 0.82
The Impact of Immunosenescence on Pulmonary Disease. Mediators Inflamm (2015) 0.80
Differences in local versus systemic TNFalpha production in COPD: inhibitory effect of hyaluronan on LPS induced blood cell TNFalpha release. Thorax (2006) 0.80
Management of asthma in the elderly patient. Clin Interv Aging (2013) 0.80
Noninvasive effects measurements for air pollution human studies: methods, analysis, and implications. J Expo Sci Environ Epidemiol (2015) 0.79
Aging and induced-sputum cells. Chest (2005) 0.79
Patterns of inflammation and the use of reversibility testing in smokers with airway complaints. BMC Pulm Med (2006) 0.79
A comparison of the clinical and induced sputum characteristics of early- and late-onset asthma. Lung (2012) 0.78
Reference ranges for induced sputum eosinophil counts in Korean adult population. Asia Pac Allergy (2014) 0.78
Ageing, smoking and oxidative stress. Thorax (2006) 0.78
Distinctive bronchial inflammation status in athletes: basophils, a new player. Eur J Appl Physiol (2012) 0.76
Use of ICS/LABA (extra-fine and non-extra-fine) in elderly asthmatics. Ther Clin Risk Manag (2016) 0.75
Changes in PH in exhaled breath condensate after specific bronchial challenge test in patients with chronic hypersensitivity pneumonitis: a prospective study. BMC Pulm Med (2015) 0.75
The evolution of sputum cytometry to assess bronchitis. Can Respir J (2013) 0.75
Influence of age and gender on the profile of exhaled volatile organic compounds analyzed by an electronic nose. J Bras Pneumol (2016) 0.75
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med (2009) 9.38
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet (2002) 8.57
Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med (2009) 8.36
Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med (2002) 6.52
Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma. Am J Respir Crit Care Med (2013) 4.95
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med (2014) 4.95
Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial. Lancet (2012) 4.94
Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med (2009) 4.83
Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med (2006) 4.83
Asthma control during the year after bronchial thermoplasty. N Engl J Med (2007) 4.79
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am J Respir Crit Care Med (2011) 3.58
Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med (2014) 3.50
Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol (2011) 3.35
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
Refining the definition of hypereosinophilic syndrome. J Allergy Clin Immunol (2010) 2.74
Fungi and allergic lower respiratory tract diseases. J Allergy Clin Immunol (2012) 2.68
Prevalence, pathogenesis, and causes of chronic cough. Lancet (2008) 2.60
The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med (2007) 2.44
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. Thorax (2007) 2.37
Exhaled nitric oxide in pulmonary diseases: a comprehensive review. Chest (2010) 2.29
Expression of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes. Am J Pathol (2002) 2.28
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J (2013) 2.16
Antiinflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2003) 2.13
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med (2011) 2.07
The Intensity of Voluntary, Induced, and Spontaneous Cough. Chest (2015) 2.00
Induced sputum inflammatory mediator concentrations in chronic cough. Am J Respir Crit Care Med (2003) 1.98
The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med (2005) 1.95
Increased sputum and bronchial biopsy IL-13 expression in severe asthma. J Allergy Clin Immunol (2008) 1.92
TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2002) 1.92
IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma. Am J Respir Crit Care Med (2010) 1.91
Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol (2005) 1.87
Antiinflammatory effects of salmeterol/fluticasone propionate in chronic obstructive lung disease. Am J Respir Crit Care Med (2006) 1.86
Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomized placebo-controlled trial. Am J Respir Crit Care Med (2012) 1.85
Bosentan in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia. Am J Respir Crit Care Med (2014) 1.73
Noneosinophilic asthma: a distinct clinical and pathologic phenotype. J Allergy Clin Immunol (2007) 1.71
Detection of cough signals in continuous audio recordings using hidden Markov models. IEEE Trans Biomed Eng (2006) 1.53
Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2004) 1.52
Dedicated Severe Asthma Services Improve Health-care Use and Quality of Life. Chest (2015) 1.50
Association between neutrophilic airway inflammation and airflow limitation in adults with asthma. Chest (2007) 1.46
Peptic ulceration, Helicobacter pylori seropositivity and chronic obstructive pulmonary disease. Respirology (2013) 1.45
Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. J Allergy Clin Immunol (2013) 1.45
A comparison of the validity of different diagnostic tests in adults with asthma. Chest (2002) 1.36
Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study. Am J Respir Crit Care Med (2002) 1.27
Long-term (5 year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trial. BMC Pulm Med (2011) 1.24
Cough frequency, cough sensitivity and health status in patients with chronic cough. Respir Med (2005) 1.22
Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma. J Allergy Clin Immunol (2010) 1.21
KCa3.1 Ca2+ activated K+ channels regulate human airway smooth muscle proliferation. Am J Respir Cell Mol Biol (2007) 1.20
Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms? Thorax (2013) 1.20
Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes. Thorax (2010) 1.19
The palliative care needs for fibrotic interstitial lung disease: a qualitative study of patients, informal caregivers and health professionals. Palliat Med (2013) 1.17
Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry. Thorax (2010) 1.15
Inflammometry: the current state of play. Thorax (2012) 1.14
Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration. J Leukoc Biol (2005) 1.14
The reclassification of asthma based on subphenotypes. Curr Opin Allergy Clin Immunol (2007) 1.14
An automated system for 24-h monitoring of cough frequency: the leicester cough monitor. IEEE Trans Biomed Eng (2007) 1.14
IL-4-expressing bronchoalveolar T cells from asthmatic and healthy subjects preferentially express CCR 3 and CCR 4. J Allergy Clin Immunol (2005) 1.13
The chemokine CXCL16 is highly and constitutively expressed by human bronchial epithelial cells. Exp Lung Res (2009) 1.12
Specialist palliative care is more than drugs: a retrospective study of ILD patients. Lung (2012) 1.07
Tools for assessing outcomes in studies of chronic cough: CHEST guideline and expert panel report. Chest (2015) 1.07
Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood. PLoS One (2011) 1.05
Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma. Am J Respir Crit Care Med (2011) 1.05
The relationship between clinical outcomes and medication adherence in difficult-to-control asthma. Thorax (2012) 1.04
CXCR6 identifies a putative population of retained human lung T cells characterised by co-expression of activation markers. Immunobiology (2008) 1.03