Published in Am J Respir Crit Care Med on February 04, 2005
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Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma. Am J Respir Crit Care Med (2011) 1.05
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IgE alone promotes human lung mast cell survival through the autocrine production of IL-6. BMC Immunol (2008) 0.94
Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis. Respir Res (2011) 0.92
Asthmatic airway smooth muscle CXCL10 production: mitogen-activated protein kinase JNK involvement. Am J Physiol Lung Cell Mol Physiol (2012) 0.91
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Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration. Eur J Immunol (2008) 0.89
Conserved nontypeable Haemophilus influenzae-derived TLR2-binding lipopeptides synergize with IFN-beta to increase cytokine production by resident murine and human alveolar macrophages. J Immunol (2006) 0.88
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CADM1 is a key receptor mediating human mast cell adhesion to human lung fibroblasts and airway smooth muscle cells. PLoS One (2013) 0.88
Ca(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model. Am J Respir Cell Mol Biol (2012) 0.88
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The multifaceted functions of CXCL10 in cardiovascular disease. Biomed Res Int (2014) 0.86
Anti-inflammatory dimethylfumarate: a potential new therapy for asthma? Mediators Inflamm (2013) 0.86
Differential regulation of chemokine expression by Th1 and Th2 cytokines and mechanisms of eotaxin/CCL-11 expression in human airway smooth muscle cells. Int Arch Allergy Immunol (2007) 0.86
The airway smooth muscle CCR3/CCL11 axis is inhibited by mast cells. Allergy (2008) 0.85
Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function. Pulm Pharmacol Ther (2012) 0.85
Mast cell-mediated and associated disorders in pregnancy: a risky game with an uncertain outcome? Front Immunol (2014) 0.84
MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells. PLoS One (2016) 0.83
CCL2 release by airway smooth muscle is increased in asthma and promotes fibrocyte migration. Allergy (2014) 0.83
Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells. J Immunol (2013) 0.82
Role of inducible nitric oxide synthase on the development of virus-associated asthma exacerbation which is dependent on Th1 and Th17 cell responses. Exp Mol Med (2010) 0.82
Effect of the Plant Derivative Compound A on the Production of Corticosteroid-Resistant Chemokines in Airway Smooth Muscle Cells. Am J Respir Cell Mol Biol (2015) 0.81
Airway smooth muscle chemokine receptor expression and function in asthma. Clin Exp Allergy (2009) 0.80
An imbalance in C/EBPs and increased mitochondrial activity in asthmatic airway smooth muscle cells: novel targets in asthma therapy? Br J Pharmacol (2009) 0.80
Risk of Migraine in Patients With Asthma: A Nationwide Cohort Study. Medicine (Baltimore) (2016) 0.79
Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells. Am J Respir Cell Mol Biol (2015) 0.79
Mast cells in airway diseases and interstitial lung disease. Eur J Pharmacol (2015) 0.79
Signalling mechanisms regulating the activation of human eosinophils by mast-cell-derived chymase: implications for mast cell-eosinophil interaction in allergic inflammation. Immunology (2008) 0.79
Time- and concentration-dependent effects of exogenous serotonin and inflammatory cytokines on mast cell function. ACS Chem Biol (2013) 0.77
Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies. Respir Res (2012) 0.77
Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma. Allergy (2016) 0.76
Airway responsiveness in CD38-deficient mice in allergic airway disease: studies with bone marrow chimeras. Am J Physiol Lung Cell Mol Physiol (2015) 0.76
Bidirectional Counterregulation of Human Lung Mast Cell and Airway Smooth Muscle β2 Adrenoceptors. J Immunol (2015) 0.76
Characteristics of Allergic Pulmonary Inflammation in CXCR3Knockout Mice Sensitized and Challenged with House Dust Mite Protein. PLoS One (2016) 0.75
Protease activated receptor-2 expression and function in asthmatic bronchial smooth muscle. PLoS One (2014) 0.75
Effect of intranasal rosiglitazone on airway inflammation and remodeling in a murine model of chronic asthma. Korean J Intern Med (2015) 0.75
Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells. Respir Res (2015) 0.75
Actin reorganization is involved in vasoactive intestinal peptide induced human mast cells priming to fraktalkine-induced chemotaxis. Int J Gen Med (2008) 0.75
No evidence for altered intracellular calcium-handling in airway smooth muscle cells from human subjects with asthma. BMC Pulm Med (2015) 0.75
Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma. Br J Pharmacol (2016) 0.75
Severe asthma in humans and mouse model suggests a CXCL10 signature underlies corticosteroid-resistant Th1 bias. JCI Insight (2017) 0.75
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet (2002) 8.57
Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med (2009) 8.36
Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med (2002) 6.52
Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma. Am J Respir Crit Care Med (2013) 4.95
Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med (2006) 4.83
Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol (2011) 3.35
Dysfunctional interaction of C/EBPalpha and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells. N Engl J Med (2004) 3.13
Refining the definition of hypereosinophilic syndrome. J Allergy Clin Immunol (2010) 2.74
Fungi and allergic lower respiratory tract diseases. J Allergy Clin Immunol (2012) 2.68
The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med (2007) 2.44
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. Thorax (2007) 2.37
Expression of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes. Am J Pathol (2002) 2.28
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol (2012) 2.24
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J (2013) 2.16
Induced sputum inflammatory mediator concentrations in chronic cough. Am J Respir Crit Care Med (2003) 1.98
Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. Lancet (2002) 1.98
Increased sputum and bronchial biopsy IL-13 expression in severe asthma. J Allergy Clin Immunol (2008) 1.92
TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2002) 1.92
IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma. Am J Respir Crit Care Med (2010) 1.91
Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol (2005) 1.87
The influence of age on induced sputum differential cell counts in normal subjects. Chest (2004) 1.82
Airway hyperresponsiveness is dissociated from airway wall structural remodeling. J Allergy Clin Immunol (2008) 1.76
Comments on Point:Counterpoint: Alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma. J Appl Physiol (1985) (2012) 1.62
PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2002) 1.57
Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma. Am J Respir Crit Care Med (2006) 1.53
Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2004) 1.52
Association between neutrophilic airway inflammation and airflow limitation in adults with asthma. Chest (2007) 1.46
C3a, mast cells, and asthma. FASEB J (2005) 1.42
Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol (2004) 1.40
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol (2011) 1.38
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease. Neuropharmacology (2009) 1.38
A comparison of the validity of different diagnostic tests in adults with asthma. Chest (2002) 1.36
Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-beta 1. J Immunol (2008) 1.34
Cooperative molecular and cellular networks regulate Toll-like receptor-dependent inflammatory responses. FASEB J (2006) 1.30
Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival. J Immunol (2007) 1.30
Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study. Am J Respir Crit Care Med (2002) 1.27
Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism. J Allergy Clin Immunol (2004) 1.27
Asthma: is it due to an abnormal airway smooth muscle cell? Am J Respir Crit Care Med (2006) 1.27
Corticosteroids reduce IL-6 in ASM cells via up-regulation of MKP-1. Am J Respir Cell Mol Biol (2008) 1.27
Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger. Thromb Res (2003) 1.25
Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol (2008) 1.23
Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma. J Allergy Clin Immunol (2010) 1.21
KCa3.1 Ca2+ activated K+ channels regulate human airway smooth muscle proliferation. Am J Respir Cell Mol Biol (2007) 1.20
IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM. Am J Physiol Lung Cell Mol Physiol (2006) 1.20
Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes. Thorax (2010) 1.19
Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: differences in asthma. J Cell Physiol (2008) 1.18
Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis. J Allergy Clin Immunol (2007) 1.17
Detection and characterization of OX40 ligand expression in human airway smooth muscle cells: a possible role in asthma? J Allergy Clin Immunol (2004) 1.16
The K+ channel iKCA1 potentiates Ca2+ influx and degranulation in human lung mast cells. J Allergy Clin Immunol (2004) 1.15
Comparison of gel contraction mediated by airway smooth muscle cells from patients with and without asthma. Thorax (2007) 1.15
Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration. J Leukoc Biol (2005) 1.14
The reclassification of asthma based on subphenotypes. Curr Opin Allergy Clin Immunol (2007) 1.14
S100A12 provokes mast cell activation: a potential amplification pathway in asthma and innate immunity. J Allergy Clin Immunol (2006) 1.14
IL-4-expressing bronchoalveolar T cells from asthmatic and healthy subjects preferentially express CCR 3 and CCR 4. J Allergy Clin Immunol (2005) 1.13
The chemokine CXCL16 is highly and constitutively expressed by human bronchial epithelial cells. Exp Lung Res (2009) 1.12
Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle. Am J Respir Crit Care Med (2005) 1.12
Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol (2005) 1.11
ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells. J Cell Physiol (2006) 1.11
β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D. PLoS One (2011) 1.10
CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. J Allergy Clin Immunol (2005) 1.08
Activation of human mast cells through the platelet-activating factor receptor. J Allergy Clin Immunol (2010) 1.08
Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood. PLoS One (2011) 1.05
Inhibition of human mast cell proliferation and survival by tamoxifen in association with ion channel modulation. J Allergy Clin Immunol (2003) 1.05
Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor. Eur J Immunol (2007) 1.04
The relationship between clinical outcomes and medication adherence in difficult-to-control asthma. Thorax (2012) 1.04
RAGE: a new frontier in chronic airways disease. Br J Pharmacol (2012) 1.04
PAR-2 activation, PGE2, and COX-2 in human asthmatic and nonasthmatic airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2003) 1.03
CXCR6 identifies a putative population of retained human lung T cells characterised by co-expression of activation markers. Immunobiology (2008) 1.03
The tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLC. PLoS One (2011) 1.01
Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration. FASEB J (2004) 1.01
Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1. J Immunol (2006) 1.00
Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. Am J Respir Crit Care Med (2003) 0.99
Beta2-adrenoceptor regulation of the K+ channel iKCa1 in human mast cells. FASEB J (2005) 0.99
Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2006) 0.99
Transforming growth factor beta 1 increases fibronectin deposition through integrin receptor alpha 5 beta 1 on human airway smooth muscle. J Allergy Clin Immunol (2008) 0.98