Published in Am J Respir Cell Mol Biol on June 21, 2007
Regulation of cell proliferation by intermediate-conductance Ca2+-activated potassium and volume-sensitive chloride channels in mouse mesenchymal stem cells. Am J Physiol Cell Physiol (2008) 1.22
Cloning and identification of tissue-specific expression of KCNN4 splice variants in rat colon. Am J Physiol Cell Physiol (2010) 1.11
Pathogenesis of allergic airway inflammation. Curr Allergy Asthma Rep (2010) 1.11
The K+ channels K(Ca)3.1 and K(v)1.3 as novel targets for asthma therapy. Br J Pharmacol (2009) 1.08
Endothelial small-conductance and intermediate-conductance KCa channels: an update on their pharmacology and usefulness as cardiovascular targets. J Cardiovasc Pharmacol (2013) 1.05
Ion channel regulation of intracellular calcium and airway smooth muscle function. Pulm Pharmacol Ther (2008) 1.01
The Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression. Drug Dev Res (2011) 0.98
Functional role of canonical transient receptor potential 1 and canonical transient receptor potential 3 in normal and asthmatic airway smooth muscle cells. Am J Respir Cell Mol Biol (2009) 0.96
CRACM/Orai ion channel expression and function in human lung mast cells. J Allergy Clin Immunol (2012) 0.96
Functional KCa3.1 K+ channels are required for human fibrocyte migration. J Allergy Clin Immunol (2011) 0.95
The intermediate conductance calcium-activated potassium channel KCa3.1 regulates vascular smooth muscle cell proliferation via controlling calcium-dependent signaling. J Biol Chem (2013) 0.93
The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis. PLoS One (2013) 0.92
Role of PGE2 in asthma and nonasthmatic eosinophilic bronchitis. Mediators Inflamm (2012) 0.91
Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration. Eur J Immunol (2008) 0.89
Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration. Pflugers Arch (2012) 0.88
Calcium-activated potassium channel KCa3.1 in lung dendritic cell migration. Am J Respir Cell Mol Biol (2011) 0.88
Activation of endothelial and epithelial K(Ca) 2.3 calcium-activated potassium channels by NS309 relaxes human small pulmonary arteries and bronchioles. Br J Pharmacol (2012) 0.88
Ca(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model. Am J Respir Cell Mol Biol (2012) 0.88
Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent. Respir Res (2014) 0.86
K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma. PLoS One (2013) 0.84
Ion channels in asthma. J Biol Chem (2011) 0.82
Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells. J Immunol (2013) 0.82
Role of the K(Ca)3.1 K+ channel in auricular lymph node CD4+ T-lymphocyte function of the delayed-type hypersensitivity model. Br J Pharmacol (2013) 0.81
The calcium-activated potassium channel KCa3.1 is an important modulator of hepatic injury. Sci Rep (2016) 0.77
Orai/CRACM1 and KCa3.1 ion channels interact in the human lung mast cell plasma membrane. Cell Commun Signal (2015) 0.76
KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells. PLoS One (2015) 0.76
Intermediate-Conductance-Ca2-Activated K Channel IKCa1 Is Upregulated and Promotes Cell Proliferation in Cervical Cancer Med Sci Monit Basic Res (2017) 0.75
Intermediate-conductance calcium-activated potassium channel KCa3.1 and chloride channel modulate chemokine ligand (CCL19/CCL21)-induced migration of dendritic cells. Transl Res (2014) 0.75
Critical role of reactive oxygen species (ROS) for synergistic enhancement of apoptosis by vemurafenib and the potassium channel inhibitor TRAM-34 in melanoma cells. Cell Death Dis (2017) 0.75
Involvement of Ca(2+)-activated K(+) channel 3.1 in hypoxia-induced pulmonary arterial hypertension and therapeutic effects of TRAM-34 in rats. Biosci Rep (2017) 0.75
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet (2002) 8.57
Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med (2009) 8.36
Mast-cell infiltration of airway smooth muscle in asthma. N Engl J Med (2002) 6.52
Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma. Am J Respir Crit Care Med (2013) 4.95
Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med (2006) 4.83
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med (2007) 2.44
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma. Thorax (2007) 2.37
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol (2012) 2.24
Vibratory Urticaria Associated with a Missense Variant in ADGRE2. N Engl J Med (2016) 2.09
Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions. N Engl J Med (2012) 2.08
A randomized phase II trial of granulocyte-macrophage colony-stimulating factor therapy in severe sepsis with respiratory dysfunction. Am J Respir Crit Care Med (2002) 2.05
Induced sputum inflammatory mediator concentrations in chronic cough. Am J Respir Crit Care Med (2003) 1.98
The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med (2005) 1.95
Endothelial coordination of cerebral vasomotion via myoendothelial gap junctions containing connexins 37 and 40. Am J Physiol Heart Circ Physiol (2006) 1.95
TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2002) 1.92
Increased sputum and bronchial biopsy IL-13 expression in severe asthma. J Allergy Clin Immunol (2008) 1.92
IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma. Am J Respir Crit Care Med (2010) 1.91
Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol (2005) 1.87
The influence of age on induced sputum differential cell counts in normal subjects. Chest (2004) 1.82
Airway hyperresponsiveness is dissociated from airway wall structural remodeling. J Allergy Clin Immunol (2008) 1.76
Refractive index measurement in viable cells using quantitative phase-amplitude microscopy and confocal microscopy. Cytometry A (2005) 1.71
Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. Mol Cell (2005) 1.58
Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma. Am J Respir Crit Care Med (2006) 1.53
Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2004) 1.52
2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer. Clin Cancer Res (2005) 1.52
Functional expression of IgG-Fc receptors in human airway smooth muscle cells. Am J Respir Cell Mol Biol (2010) 1.51
Dedicated Severe Asthma Services Improve Health-care Use and Quality of Life. Chest (2015) 1.50
Evidence for involvement of both IKCa and SKCa channels in hyperpolarizing responses of the rat middle cerebral artery. Stroke (2006) 1.45
C3a, mast cells, and asthma. FASEB J (2005) 1.42
The structure of the peripheral stalk of Thermus thermophilus H+-ATPase/synthase. Nat Struct Mol Biol (2010) 1.42
Proliferative aspects of airway smooth muscle. J Allergy Clin Immunol (2004) 1.40
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol (2011) 1.38
Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-beta 1. J Immunol (2008) 1.34
Cooperative molecular and cellular networks regulate Toll-like receptor-dependent inflammatory responses. FASEB J (2006) 1.30
Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival. J Immunol (2007) 1.30
Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study. Am J Respir Crit Care Med (2002) 1.27
Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol (2008) 1.23
2-Methoxyestradiol--a unique blend of activities generating a new class of anti-tumour/anti-inflammatory agents. Drug Discov Today (2007) 1.21
Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation. J Allergy Clin Immunol (2013) 1.19
Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes. Thorax (2010) 1.19
Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis. J Allergy Clin Immunol (2007) 1.17
The K+ channel iKCA1 potentiates Ca2+ influx and degranulation in human lung mast cells. J Allergy Clin Immunol (2004) 1.15
Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry. Thorax (2010) 1.15
Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration. J Leukoc Biol (2005) 1.14
The reclassification of asthma based on subphenotypes. Curr Opin Allergy Clin Immunol (2007) 1.14
On the terminology for describing the length-force relationship and its changes in airway smooth muscle. J Appl Physiol (1985) (2004) 1.12
Activation of human mast cells through the platelet-activating factor receptor. J Allergy Clin Immunol (2010) 1.08
Annexin-1 signals mitogen-stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2. FASEB J (2010) 1.06
Inhibition of human mast cell proliferation and survival by tamoxifen in association with ion channel modulation. J Allergy Clin Immunol (2003) 1.05
Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma. Am J Respir Crit Care Med (2011) 1.05
Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor. Eur J Immunol (2007) 1.04
The relationship between clinical outcomes and medication adherence in difficult-to-control asthma. Thorax (2012) 1.04
Collagen-induced resistance to glucocorticoid anti-mitogenic actions: a potential explanation of smooth muscle hyperplasia in the asthmatic remodelled airway. Br J Pharmacol (2003) 1.04
The tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLC. PLoS One (2011) 1.01
Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1. J Immunol (2006) 1.00
Expression of intermediate conductance potassium channel immunoreactivity in neurons and epithelial cells of the rat gastrointestinal tract. Cell Tissue Res (2003) 0.99
Beta2-adrenoceptor regulation of the K+ channel iKCa1 in human mast cells. FASEB J (2005) 0.99
Airway remodelling in asthma: current understanding and implications for future therapies. Pharmacol Ther (2006) 0.97
Extracellular matrix, integrins, and mesenchymal cell function in the airways. Curr Drug Targets (2006) 0.96
Chromosome 17q21 SNP and severe asthma. J Hum Genet (2010) 0.96
Human lung mast cells mediate pneumococcal cell death in response to activation by pneumolysin. J Immunol (2010) 0.96
CRACM/Orai ion channel expression and function in human lung mast cells. J Allergy Clin Immunol (2012) 0.96
Glucocorticoid-resistant asthma and novel anti-inflammatory drugs. Drug Discov Today (2012) 0.95
Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma. Thorax (2011) 0.95
PPAR gamma ligands, 15-deoxy-delta12,14-prostaglandin J2 and rosiglitazone regulate human cultured airway smooth muscle proliferation through different mechanisms. Br J Pharmacol (2004) 0.95
Functional KCa3.1 K+ channels are required for human fibrocyte migration. J Allergy Clin Immunol (2011) 0.95
Chemokine receptor expression in tumour islets and stroma in non-small cell lung cancer. BMC Cancer (2010) 0.95
IgE alone promotes human lung mast cell survival through the autocrine production of IL-6. BMC Immunol (2008) 0.94
CCL11 and GM-CSF differentially use the Rho GTPase pathway to regulate motility of human eosinophils in a three-dimensional microenvironment. J Immunol (2008) 0.92
Tissue and matrix influences on airway smooth muscle function. Pulm Pharmacol Ther (2008) 0.92
A novel magnetic bead-based assay with high sensitivity and selectivity for analysis of telomerase in exfoliated cells from patients with bladder and colon cancer. Electrophoresis (2007) 0.92
Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle. Br J Pharmacol (2003) 0.90
Transforming growth factor-β-induced differentiation of airway smooth muscle cells is inhibited by fibroblast growth factor-2. Am J Respir Cell Mol Biol (2012) 0.90
Quantitative phase microscopy: a new tool for measurement of cell culture growth and confluency in situ. Pflugers Arch (2004) 0.90