PubRank

Karen M Lyons

Author PubWeight™ 78.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development 2003 4.31
2 Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development 2004 3.46
3 Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci U S A 2005 2.82
4 Autoregulation of neurogenesis by GDF11. Neuron 2003 2.40
5 BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development 2009 2.21
6 GDF11 controls the timing of progenitor cell competence in developing retina. Science 2005 2.04
7 CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. J Biol Chem 2006 1.96
8 BMP signaling is required for septation of the outflow tract of the mammalian heart. Development 2003 1.95
9 Multiple functions of BMPs in chondrogenesis. J Cell Biochem 2004 1.92
10 CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin. Mol Biol Cell 2004 1.83
11 Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis. Hum Mol Genet 2006 1.74
12 BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development 2006 1.59
13 CCN2 is necessary for the function of mouse embryonic fibroblasts. Exp Cell Res 2006 1.57
14 CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes. J Biochem 2008 1.55
15 Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res 2008 1.51
16 BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci U S A 2005 1.44
17 Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling. Proc Natl Acad Sci U S A 2006 1.34
18 Distinct developmental programs require different levels of Bmp signaling during mouse retinal development. Development 2005 1.33
19 CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One 2012 1.33
20 Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells. J Bone Miner Res 2010 1.29
21 Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem 2005 1.28
22 Tempting fate: BMP signals for cardiac morphogenesis. Cytokine Growth Factor Rev 2003 1.26
23 Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis. Mol Endocrinol 2009 1.24
24 CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes. J Cell Commun Signal 2007 1.24
25 BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. J Neurosci 2010 1.22
26 A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J Mol Biol 2008 1.21
27 CTGF inhibits BMP-7 signaling in diabetic nephropathy. J Am Soc Nephrol 2008 1.19
28 Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development 2004 1.18
29 Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development. Mol Endocrinol 2010 1.17
30 Smad signaling in skeletal development and regeneration. Cytokine Growth Factor Rev 2009 1.17
31 Angiogenesis is not impaired in connective tissue growth factor (CTGF) knock-out mice. J Histochem Cytochem 2007 1.10
32 Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn 2004 1.08
33 Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis. Int J Oncol 2011 1.07
34 Roles for CCN2 in normal physiological processes. Cell Mol Life Sci 2011 1.06
35 Focal adhesion kinase/Src suppresses early chondrogenesis: central role of CCN2. J Biol Chem 2008 1.04
36 BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression. J Histochem Cytochem 2009 1.04
37 Functional requirement of CCN2 for intramembranous bone formation in embryonic mice. Biochem Biophys Res Commun 2007 1.03
38 Smad6 is essential to limit BMP signaling during cartilage development. J Bone Miner Res 2011 1.02
39 Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling. Am J Hum Genet 2012 1.02
40 CCN family 2/connective tissue growth factor (CCN2/CTGF) promotes osteoclastogenesis via induction of and interaction with dendritic cell-specific transmembrane protein (DC-STAMP). J Bone Miner Res 2011 0.96
41 Connective tissue growth factor is required for normal follicle development and ovulation. Mol Endocrinol 2011 0.96
42 Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development 2005 0.95
43 Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice. J Histochem Cytochem 2008 0.95
44 CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1alpha expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition. Bone 2008 0.95
45 Stage-specific control of connective tissue growth factor (CTGF/CCN2) expression in chondrocytes by Sox9 and beta-catenin. J Biol Chem 2010 0.93
46 Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity. J Biol Chem 2013 0.87
47 Tracking expression of virally mediated BMP-2 in gene therapy for bone repair. Clin Orthop Relat Res 2006 0.86
48 Fungal laryngitis. Ear Nose Throat J 2009 0.85
49 Whole-mount skeletal staining. Methods Mol Biol 2014 0.85
50 TGFβ signaling in cartilage development and maintenance. Birth Defects Res C Embryo Today 2014 0.85
51 The 5' untranslated regions (UTRs) of CCN1, CCN2, and CCN4 exhibit cryptic promoter activity. J Cell Commun Signal 2007 0.85
52 Systems genetics analysis of mouse chondrocyte differentiation. J Bone Miner Res 2011 0.84
53 The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development. J Bone Miner Res 2015 0.84
54 Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization. J Theor Biol 2011 0.82
55 ENU large-scale mutagenesis and quantitative trait linkage (QTL) analysis in mice: novel technologies for searching polygenetic determinants of craniofacial abnormalities. Crit Rev Oral Biol Med 2003 0.82
56 Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol 2013 0.81
57 Laryngeal thrush from asthma inhalers. Ear Nose Throat J 2012 0.78
58 Dynamic analysis of the expression of the TGFbeta/SMAD2 pathway and CCN2/CTGF during early steps of tooth development. Cells Tissues Organs 2007 0.78
59 CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress. J Cell Commun Signal 2013 0.78
60 CCN2 as a novel molecule supporting energy metabolism of chondrocytes. J Cell Biochem 2014 0.77