|
1
|
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells.
|
Hepatology
|
2010
|
6.40
|
|
2
|
Architectural protein subclasses shape 3D organization of genomes during lineage commitment.
|
Cell
|
2013
|
6.37
|
|
3
|
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.
|
Development
|
2005
|
5.80
|
|
4
|
Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types.
|
Genome Res
|
2010
|
4.67
|
|
5
|
Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis.
|
Genome Res
|
2009
|
3.36
|
|
6
|
Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities.
|
Oncogene
|
2002
|
3.06
|
|
7
|
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.
|
Stem Cells
|
2007
|
3.04
|
|
8
|
Preserving the genetic integrity of human embryonic stem cells.
|
Nat Biotechnol
|
2005
|
3.03
|
|
9
|
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming.
|
Cell Stem Cell
|
2009
|
2.72
|
|
10
|
Cell cycle control of embryonic stem cells.
|
Stem Cell Rev
|
2005
|
2.64
|
|
11
|
Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation.
|
Mol Biol Cell
|
2005
|
2.00
|
|
12
|
Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation.
|
Cell Stem Cell
|
2012
|
1.94
|
|
13
|
Myc represses primitive endoderm differentiation in pluripotent stem cells.
|
Cell Stem Cell
|
2010
|
1.90
|
|
14
|
Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells.
|
Proc Natl Acad Sci U S A
|
2011
|
1.56
|
|
15
|
Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation.
|
J Proteome Res
|
2007
|
1.46
|
|
16
|
Recruitment of Thr 319-phosphorylated Ndd1p to the FHA domain of Fkh2p requires Clb kinase activity: a mechanism for CLB cluster gene activation.
|
Genes Dev
|
2003
|
1.45
|
|
17
|
Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a).
|
Oncogene
|
2004
|
1.35
|
|
18
|
Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal.
|
Mol Cell Biol
|
2009
|
1.31
|
|
19
|
Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation.
|
PLoS Pathog
|
2012
|
1.29
|
|
20
|
Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells.
|
Cell Rep
|
2012
|
1.27
|
|
21
|
Replication timing: a fingerprint for cell identity and pluripotency.
|
PLoS Comput Biol
|
2011
|
1.21
|
|
22
|
Human motor neuron differentiation from human embryonic stem cells.
|
Stem Cells Dev
|
2005
|
1.15
|
|
23
|
IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells.
|
J Proteome Res
|
2009
|
1.15
|
|
24
|
Roles for MYC in the establishment and maintenance of pluripotency.
|
Cold Spring Harb Perspect Med
|
2013
|
1.06
|
|
25
|
Directed differentiation of human pluripotent cells to neural crest stem cells.
|
Nat Protoc
|
2013
|
1.04
|
|
26
|
MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7.
|
Genes Dev
|
2013
|
1.04
|
|
27
|
Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells.
|
J Biol Chem
|
2012
|
1.03
|
|
28
|
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17.
|
J Proteome Res
|
2012
|
1.03
|
|
29
|
Myc transcription factors: key regulators behind establishment and maintenance of pluripotency.
|
Regen Med
|
2010
|
1.00
|
|
30
|
Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis.
|
J Biol Chem
|
2012
|
0.97
|
|
31
|
Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency.
|
Cell Cycle
|
2011
|
0.94
|
|
32
|
Glycoproteomic analysis of embryonic stem cells: identification of potential glycobiomarkers using lectin affinity chromatography of glycopeptides.
|
J Proteome Res
|
2010
|
0.93
|
|
33
|
Transcriptional profiling of initial differentiation events in human embryonic stem cells.
|
Biochem Biophys Res Commun
|
2004
|
0.93
|
|
34
|
The lectin Dolichos biflorus agglutinin recognizes glycan epitopes on the surface of murine embryonic stem cells: a new tool for characterizing pluripotent cells and early differentiation.
|
Stem Cells
|
2006
|
0.91
|
|
35
|
Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells.
|
Mol Cell Biol
|
2011
|
0.91
|
|
36
|
Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies.
|
J Lipid Res
|
2009
|
0.89
|
|
37
|
Heparan sulfate: a key regulator of embryonic stem cell fate.
|
Biol Chem
|
2013
|
0.86
|
|
38
|
Transcriptional profiling of definitive endoderm derived from human embryonic stem cells.
|
Comput Syst Bioinformatics Conf
|
2007
|
0.86
|
|
39
|
Reconciling the different roles of Gsk3β in "naïve" and "primed" pluripotent stem cells.
|
Cell Cycle
|
2012
|
0.83
|
|
40
|
Lectin-functionalized microchannels for characterizing pluripotent cells and early differentiation.
|
Biomicrofluidics
|
2012
|
0.80
|
|
41
|
Altered cell cycle regulation helps stem-like carcinoma cells resist apoptosis.
|
BMC Biol
|
2010
|
0.78
|
|
42
|
Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells.
|
Stem Cell Reports
|
2014
|
0.75
|
|
43
|
NHS England chief executive: welcome back, Simon. Here's your to-do list.
|
Health Serv J
|
2014
|
0.75
|