Published in BMC Genomics on January 27, 2005
Genetic variation in the zebrafish. Genome Res (2006) 2.22
Large-scale mapping of mutations affecting zebrafish development. BMC Genomics (2007) 1.21
Generation and analysis of ESTs from the eastern oyster, Crassostrea virginica Gmelin and identification of microsatellite and SNP markers. BMC Genomics (2007) 1.13
Identifying functional single nucleotide polymorphisms in the human CArGome. Physiol Genomics (2011) 1.11
A major zebrafish polymorphism resource for genetic mapping. Genome Biol (2007) 1.08
Seq4SNPs: new software for retrieval of multiple, accurately annotated DNA sequences, ready formatted for SNP assay design. BMC Bioinformatics (2009) 0.88
SNP discovery by mismatch-targeting of Mu transposition. Nucleic Acids Res (2007) 0.81
SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res (2003) 52.26
Human non-synonymous SNPs: server and survey. Nucleic Acids Res (2002) 50.45
Mining SNPs from EST databases. Genome Res (1999) 4.31
Single nucleotide polymorphisms associated with rat expressed sequences. Genome Res (2004) 1.43
GENOTRACE: cDNA-based local GENOme assembly from TRACE archives. Bioinformatics (2002) 1.25
MicroRNA expression in zebrafish embryonic development. Science (2005) 15.52
Phylogenetic shadowing and computational identification of human microRNA genes. Cell (2005) 13.24
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Diversity of microRNAs in human and chimpanzee brain. Nat Genet (2006) 6.57
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell (2007) 6.31
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
Mammalian mirtron genes. Mol Cell (2007) 5.75
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. Genome Res (2006) 5.23
The microRNA-producing enzyme Dicer1 is essential for zebrafish development. Nat Genet (2003) 4.97
Limitations and possibilities of small RNA digital gene expression profiling. Nat Methods (2009) 4.34
Approaches to microRNA discovery. Nat Genet (2006) 4.32
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell (2013) 3.97
Disclosure of individual genetic data to research participants: the debate reconsidered. Trends Genet (2010) 3.83
Efficient target-selected mutagenesis in zebrafish. Genome Res (2003) 3.61
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell (2009) 3.60
A systematic genome-wide analysis of zebrafish protein-coding gene function. Nature (2013) 3.52
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline. Mol Cell (2008) 3.37
Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries. Nucleic Acids Res (2010) 3.23
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol Cell Biol (2008) 3.02
SNP and haplotype mapping for genetic analysis in the rat. Nat Genet (2008) 2.96
The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature (2003) 2.89
Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nat Genet (2010) 2.84
Detection of microRNAs in frozen tissue sections by fluorescence in situ hybridization using locked nucleic acid probes and tyramide signal amplification. Nat Protoc (2007) 2.80
Abundant primary piRNAs, endo-siRNAs, and microRNAs in a Drosophila ovary cell line. Genome Res (2009) 2.68
Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms. Cell Rep (2012) 2.67
Cloning and expression of new microRNAs from zebrafish. Nucleic Acids Res (2006) 2.58
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell (2012) 2.45
Differences in vertebrate microRNA expression. Proc Natl Acad Sci U S A (2006) 2.45
Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline. Hum Mol Genet (2011) 2.43
Ethical, legal, and counseling challenges surrounding the return of genetic results in oncology. J Clin Oncol (2013) 2.36
Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci. Genes Dev (2008) 2.35
Genetic variation in the zebrafish. Genome Res (2006) 2.22
Distribution and functional impact of DNA copy number variation in the rat. Nat Genet (2008) 2.20
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol (2011) 2.11
Mouse microRNA profiles determined with a new and sensitive cloning method. Nucleic Acids Res (2006) 1.94
CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs. Cell (2009) 1.94
Zili is required for germ cell differentiation and meiosis in zebrafish. EMBO J (2008) 1.87
LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition. Diabetes (2007) 1.83
Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr Biol (2008) 1.80
Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples. Nat Methods (2010) 1.77
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. Genome Biol (2014) 1.66
microRNAs associated with the different human Argonaute proteins. Nucleic Acids Res (2012) 1.66
Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment. Clin Cancer Res (2011) 1.64
Repertoire and evolution of miRNA genes in four divergent nematode species. Genome Res (2009) 1.64
Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet Genomics (2006) 1.60
CONREAL: conserved regulatory elements anchored alignment algorithm for identification of transcription factor binding sites by phylogenetic footprinting. Genome Res (2003) 1.57
Zebrafish as a cancer model. Mol Cancer Res (2008) 1.55
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell (2013) 1.53
Hen1 is required for oocyte development and piRNA stability in zebrafish. EMBO J (2010) 1.53
Dominant missense mutations in ABCC9 cause Cantú syndrome. Nat Genet (2012) 1.50
Melanocortin receptor 4 deficiency affects body weight regulation, grooming behavior, and substrate preference in the rat. Obesity (Silver Spring) (2011) 1.50
Zebrafish development and regeneration: new tools for biomedical research. Int J Dev Biol (2009) 1.46
The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance. Genome Res (2010) 1.45
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis. Ann Neurol (2011) 1.45
Single nucleotide polymorphisms associated with rat expressed sequences. Genome Res (2004) 1.43
Extremely stable Piwi-induced gene silencing in Caenorhabditis elegans. EMBO J (2012) 1.41
Systematic biases in DNA copy number originate from isolation procedures. Genome Biol (2013) 1.39
Multiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencing. Nat Protoc (2011) 1.36
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nat Genet (2013) 1.30
Generation of medaka gene knockout models by target-selected mutagenesis. Genome Biol (2006) 1.30
Small RNAs and the control of transposons and viruses in Drosophila. Trends Microbiol (2009) 1.27
Target-selected mutagenesis of the rat. Genomics (2004) 1.26
E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. Nucleic Acids Res (2011) 1.26
GENOTRACE: cDNA-based local GENOme assembly from TRACE archives. Bioinformatics (2002) 1.25
CONREAL web server: identification and visualization of conserved transcription factor binding sites. Nucleic Acids Res (2005) 1.25
Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling. Mol Syst Biol (2013) 1.24
Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b. Development (2010) 1.23
Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans. PLoS Genet (2012) 1.20
Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq. Bioinformatics (2010) 1.18
Small RNA expression and strain specificity in the rat. BMC Genomics (2010) 1.16
Genomic and transcriptomic plasticity in treatment-naive ovarian cancer. Genome Res (2013) 1.15
High-throughput target-selected gene inactivation in zebrafish. Methods Cell Biol (2011) 1.15
Expanding the spectrum of phenotypes associated with germline PIGA mutations: a child with developmental delay, accelerated linear growth, facial dysmorphisms, elevated alkaline phosphatase, and progressive CNS abnormalities. Am J Med Genet A (2013) 1.14
Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals. BMC Genomics (2008) 1.14
Dominant-negative ALK2 allele associates with congenital heart defects. Circulation (2009) 1.14
Haplotype block structure is conserved across mammals. PLoS Genet (2006) 1.13
Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles. PLoS One (2010) 1.12
High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors. Genome Res (2011) 1.12
Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach. BMC Genomics (2011) 1.10
Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. Eur J Neurosci (2007) 1.08
FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands. Arch Neurol (2010) 1.08
Tracing the history of goat pastoralism: new clues from mitochondrial and Y chromosome DNA in North Africa. Mol Biol Evol (2009) 1.07
Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos. RNA (2009) 1.07
Expression patterns of intronic microRNAs in Caenorhabditis elegans. Silence (2010) 1.06
Serotonin transporter dosage modulates long-term decision-making in rat and human. Neuropharmacology (2008) 1.06
Chromothripsis in congenital disorders and cancer: similarities and differences. Curr Opin Cell Biol (2013) 1.05
Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain. Epigenetics Chromatin (2013) 1.05
MicroRNA-directed siRNA biogenesis in Caenorhabditis elegans. PLoS Genet (2010) 1.05
Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. EMBO J (2014) 1.05
A deep sequencing approach to uncover the miRNOME in the human heart. PLoS One (2013) 1.04
RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans. EMBO J (2007) 1.04
Genomic DNA pooling strategy for next-generation sequencing-based rare variant discovery in abdominal aortic aneurysm regions of interest-challenges and limitations. J Cardiovasc Transl Res (2011) 1.04
Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats. Psychopharmacology (Berl) (2007) 1.03