Published in Development on April 01, 2010
COPII and the regulation of protein sorting in mammals. Nat Cell Biol (2011) 2.33
Neural tube defects: recent advances, unsolved questions, and controversies. Lancet Neurol (2013) 1.68
Comparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell development. PLoS One (2012) 1.22
COPII - a flexible vesicle formation system. Curr Opin Cell Biol (2013) 1.14
The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C. J Biol Chem (2011) 1.11
Shaping the nervous system: role of the core planar cell polarity genes. Nat Rev Neurosci (2013) 1.11
The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol (2010) 1.06
Vesicle-mediated ER export of proteins and lipids. Biochim Biophys Acta (2012) 1.06
The COPII pathway and hematologic disease. Blood (2012) 1.03
Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse. Genetics (2011) 1.02
Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol (2012) 1.01
Mechanisms of tissue fusion during development. Development (2012) 0.99
Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2. J Neurosci (2013) 0.97
PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol (2012) 0.96
Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C. J Biol Chem (2013) 0.95
Initiation of synapse formation by Wnt-induced MuSK endocytosis. Development (2012) 0.95
The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions. Mol Cell Proteomics (2013) 0.94
Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear. Development (2012) 0.93
Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes. PLoS One (2012) 0.92
Planar polarity: A new player in both lung development and disease. Organogenesis (2011) 0.90
Mechanisms for exporting large-sized cargoes from the endoplasmic reticulum. Cell Mol Life Sci (2015) 0.89
An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions. PLoS One (2011) 0.88
Wolbachia bacteria reside in host Golgi-related vesicles whose position is regulated by polarity proteins. PLoS One (2011) 0.87
Age-related changes in the cellular composition and epithelial organization of the mouse trachea. PLoS One (2014) 0.84
Trafficking mechanisms of extracellular matrix macromolecules: insights from vertebrate development and human diseases. Int J Biochem Cell Biol (2013) 0.83
Evidence for the involvement of the Arabidopsis SEC24A in male transmission. J Exp Bot (2011) 0.83
Planar cell polarity signaling in craniofacial development. Organogenesis (2011) 0.82
Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice. Sci Rep (2015) 0.81
Planar cell polarity signaling pathway in congenital heart diseases. J Biomed Biotechnol (2011) 0.80
Spectrin binding motifs regulate Scribble cortical dynamics and polarity function. Elife (2015) 0.77
Heterozygous Vangl2(Looptail) mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair. Dis Model Mech (2017) 0.75
Planar cell polarity in moving cells: think globally, act locally. Development (2017) 0.75
The intracellular carboxyl terminal domain of Vangl proteins contains plasma membrane targeting signals. Protein Sci (2014) 0.75
Phylogenetic shadowing and computational identification of human microRNA genes. Cell (2005) 13.24
Diversity of microRNAs in human and chimpanzee brain. Nat Genet (2006) 6.57
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
Mammalian mirtron genes. Mol Cell (2007) 5.75
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. Genome Res (2006) 5.23
The microRNA-producing enzyme Dicer1 is essential for zebrafish development. Nat Genet (2003) 4.97
Limitations and possibilities of small RNA digital gene expression profiling. Nat Methods (2009) 4.34
Approaches to microRNA discovery. Nat Genet (2006) 4.32
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients. Cell Stem Cell (2013) 3.97
Disclosure of individual genetic data to research participants: the debate reconsidered. Trends Genet (2010) 3.83
Efficient target-selected mutagenesis in zebrafish. Genome Res (2003) 3.61
A systematic genome-wide analysis of zebrafish protein-coding gene function. Nature (2013) 3.52
Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries. Nucleic Acids Res (2010) 3.23
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol Cell Biol (2008) 3.02
SNP and haplotype mapping for genetic analysis in the rat. Nat Genet (2008) 2.96
Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci (2004) 2.93
The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature (2003) 2.89
Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol (2010) 2.67
Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms. Cell Rep (2012) 2.67
Cloning and expression of new microRNAs from zebrafish. Nucleic Acids Res (2006) 2.58
Progression of vertebrate limb development through SHH-mediated counteraction of GLI3. Science (2002) 2.45
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell (2012) 2.45
Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline. Hum Mol Genet (2011) 2.43
Ethical, legal, and counseling challenges surrounding the return of genetic results in oncology. J Clin Oncol (2013) 2.36
Genetic variation in the zebrafish. Genome Res (2006) 2.22
Distribution and functional impact of DNA copy number variation in the rat. Nat Genet (2008) 2.20
Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea. Development (2003) 2.18
Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. Nat Neurosci (2010) 2.18
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol (2011) 2.11
Mouse microRNA profiles determined with a new and sensitive cloning method. Nucleic Acids Res (2006) 1.94
Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr Biol (2008) 1.80
Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples. Nat Methods (2010) 1.77
Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene. Hum Mol Genet (2004) 1.73
Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development. Circulation (2007) 1.72
Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti. J Neurosci (2006) 1.68
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. Genome Biol (2014) 1.66
Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment. Clin Cancer Res (2011) 1.64
Repertoire and evolution of miRNA genes in four divergent nematode species. Genome Res (2009) 1.64
Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet Genomics (2006) 1.60
CONREAL: conserved regulatory elements anchored alignment algorithm for identification of transcription factor binding sites by phylogenetic footprinting. Genome Res (2003) 1.57
Zebrafish as a cancer model. Mol Cancer Res (2008) 1.55
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell (2013) 1.53
Dominant missense mutations in ABCC9 cause Cantú syndrome. Nat Genet (2012) 1.50
Melanocortin receptor 4 deficiency affects body weight regulation, grooming behavior, and substrate preference in the rat. Obesity (Silver Spring) (2011) 1.50
Zebrafish development and regeneration: new tools for biomedical research. Int J Dev Biol (2009) 1.46
The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance. Genome Res (2010) 1.45
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis. Ann Neurol (2011) 1.45
Single nucleotide polymorphisms associated with rat expressed sequences. Genome Res (2004) 1.43
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis. Gut (2011) 1.40
Systematic biases in DNA copy number originate from isolation procedures. Genome Biol (2013) 1.39
Multiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencing. Nat Protoc (2011) 1.36
Dorsoventral patterning of the mouse coat by Tbx15. PLoS Biol (2004) 1.36
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nat Genet (2013) 1.30
Generation of medaka gene knockout models by target-selected mutagenesis. Genome Biol (2006) 1.30
Target-selected mutagenesis of the rat. Genomics (2004) 1.26
E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. Nucleic Acids Res (2011) 1.26
GENOTRACE: cDNA-based local GENOme assembly from TRACE archives. Bioinformatics (2002) 1.25
CONREAL web server: identification and visualization of conserved transcription factor binding sites. Nucleic Acids Res (2005) 1.25
Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling. Mol Syst Biol (2013) 1.24
Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq. Bioinformatics (2010) 1.18
Scrib regulates PAK activity during the cell migration process. Hum Mol Genet (2008) 1.17
Small RNA expression and strain specificity in the rat. BMC Genomics (2010) 1.16
Genomic and transcriptomic plasticity in treatment-naive ovarian cancer. Genome Res (2013) 1.15
High-throughput target-selected gene inactivation in zebrafish. Methods Cell Biol (2011) 1.15
Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain. EMBO J (2003) 1.15
Expanding the spectrum of phenotypes associated with germline PIGA mutations: a child with developmental delay, accelerated linear growth, facial dysmorphisms, elevated alkaline phosphatase, and progressive CNS abnormalities. Am J Med Genet A (2013) 1.14
Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals. BMC Genomics (2008) 1.14
Dominant-negative ALK2 allele associates with congenital heart defects. Circulation (2009) 1.14
Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton. Nat Cell Biol (2013) 1.13
Haplotype block structure is conserved across mammals. PLoS Genet (2006) 1.13
Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles. PLoS One (2010) 1.12
Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes. Development (2005) 1.12
High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors. Genome Res (2011) 1.12
The planar cell polarity pathway in vertebrate development. Dev Dyn (2011) 1.11
Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach. BMC Genomics (2011) 1.10
Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. Eur J Neurosci (2007) 1.08
FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands. Arch Neurol (2010) 1.08
Tracing the history of goat pastoralism: new clues from mitochondrial and Y chromosome DNA in North Africa. Mol Biol Evol (2009) 1.07
Serotonin transporter dosage modulates long-term decision-making in rat and human. Neuropharmacology (2008) 1.06
Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain. Epigenetics Chromatin (2013) 1.05
Chromothripsis in congenital disorders and cancer: similarities and differences. Curr Opin Cell Biol (2013) 1.05
Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. EMBO J (2014) 1.05
A deep sequencing approach to uncover the miRNOME in the human heart. PLoS One (2013) 1.04
RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans. EMBO J (2007) 1.04
Genomic DNA pooling strategy for next-generation sequencing-based rare variant discovery in abdominal aortic aneurysm regions of interest-challenges and limitations. J Cardiovasc Transl Res (2011) 1.04
Revisiting planar cell polarity in the inner ear. Semin Cell Dev Biol (2013) 1.04
Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone. Development (2011) 1.04
CASCAD: a database of annotated candidate single nucleotide polymorphisms associated with expressed sequences. BMC Genomics (2005) 1.03
Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats. Psychopharmacology (Berl) (2007) 1.03
Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes. Nucleic Acids Res (2011) 1.02
Discovery of variants unmasked by hemizygous deletions. Eur J Hum Genet (2012) 1.02
Genetic variation in coding regions between and within commonly used inbred rat strains. Genome Res (2004) 1.01
A functional screen identifies specific microRNAs capable of inhibiting human melanoma cell viability. PLoS One (2012) 1.00
A genome-wide SNP panel for mapping and association studies in the rat. BMC Genomics (2008) 1.00
Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system. Eur J Neurosci (2007) 1.00
miR-127 protects proximal tubule cells against ischemia/reperfusion: identification of kinesin family member 3B as miR-127 target. PLoS One (2012) 1.00
ENU mutagenesis to generate genetically modified rat models. Methods Mol Biol (2010) 1.00