Published in J Biol Chem on September 02, 2006
Eukaryotic stress granules: the ins and outs of translation. Mol Cell (2009) 6.09
P bodies promote stress granule assembly in Saccharomyces cerevisiae. J Cell Biol (2008) 3.45
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem (2010) 2.61
RNA granules: the good, the bad and the ugly. Cell Signal (2010) 2.31
Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules. Mol Biol Cell (2007) 2.30
P bodies, stress granules, and viral life cycles. Cell Host Microbe (2008) 2.23
Stress granules and cell signaling: more than just a passing phase? Trends Biochem Sci (2013) 2.01
Regulated protein aggregation: stress granules and neurodegeneration. Mol Neurodegener (2012) 1.95
Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress. Radiat Res (2009) 1.88
Accumulation of polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-bodies in Saccharomyces cerevisiae. Mol Biol Cell (2007) 1.83
LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNA interference RNA-induced silencing complex. Mol Cell Biol (2007) 1.79
Inhibition of the ubiquitin-proteasome system induces stress granule formation. Mol Biol Cell (2007) 1.75
Hypoxic inhibition of nonsense-mediated RNA decay regulates gene expression and the integrated stress response. Mol Cell Biol (2008) 1.68
Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169. J Cell Sci (2008) 1.64
Ribosomal slowdown mediates translational arrest during cellular division. Mol Cell Biol (2007) 1.62
Regulation of c-Src nonreceptor tyrosine kinase activity by bengamide A through inhibition of methionine aminopeptidases. Chem Biol (2007) 1.58
The biological and therapeutic relevance of mRNA translation in cancer. Nat Rev Clin Oncol (2011) 1.54
Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication. J Virol (2010) 1.51
Uncoupling stress granule assembly and translation initiation inhibition. Mol Biol Cell (2009) 1.49
Rotavirus infection induces the phosphorylation of eIF2alpha but prevents the formation of stress granules. J Virol (2007) 1.49
Regulation of stress granules in virus systems. Trends Microbiol (2012) 1.46
Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A. EMBO J (2007) 1.42
Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations. Nucleic Acids Res (2010) 1.39
Stable formation of compositionally unique stress granules in virus-infected cells. J Virol (2010) 1.34
Diversion of stress granules and P-bodies during viral infection. Virology (2013) 1.33
Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay in Saccharomyces cerevisiae. J Cell Biol (2010) 1.31
Mammalian Staufen 1 is recruited to stress granules and impairs their assembly. J Cell Sci (2009) 1.30
Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells. Br J Cancer (2009) 1.25
Metazoan stress granule assembly is mediated by P-eIF2alpha-dependent and -independent mechanisms. RNA (2009) 1.23
Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection. Mol Biol Cell (2012) 1.22
The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly. Elife (2015) 1.19
Stress granules, P-bodies and cancer. Biochim Biophys Acta (2014) 1.17
Modulation of stress granules and P bodies during dicistrovirus infection. J Virol (2010) 1.14
Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A. Mol Cancer Ther (2009) 1.10
Large G3BP-induced granules trigger eIF2α phosphorylation. Mol Biol Cell (2012) 1.10
Translation arrest and ribonomics in post-ischemic brain: layers and layers of players. J Neurochem (2008) 1.10
Mammalian orthoreovirus particles induce and are recruited into stress granules at early times postinfection. J Virol (2009) 1.08
Angiogenin-mediated rRNA transcription in cancer and neurodegeneration. Int J Biochem Mol Biol (2010) 1.06
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice. Nat Commun (2012) 1.05
Regulation of stress granules and P-bodies during RNA virus infection. Wiley Interdiscip Rev RNA (2013) 1.03
The chemotherapeutic agent bortezomib induces the formation of stress granules. Cancer Cell Int (2010) 1.02
Mammalian orthoreovirus escape from host translational shutoff correlates with stress granule disruption and is independent of eIF2alpha phosphorylation and PKR. J Virol (2011) 0.99
Poliovirus unlinks TIA1 aggregation and mRNA stress granule formation. J Virol (2011) 0.99
Characterizing mRNA interactions with RNA granules during translation initiation inhibition. PLoS One (2011) 0.99
Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation. Biochem Biophys Res Commun (2012) 0.98
Analysis of stress granule assembly in Schizosaccharomyces pombe. RNA (2012) 0.97
Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. Nucleic Acids Res (2012) 0.96
Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII. J Biol Chem (2009) 0.96
Oxidative Stress Increases the Number of Stress Granules in Senescent Cells and Triggers a Rapid Decrease in p21waf1/cip1 Translation. J Biol Chem (2009) 0.95
Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae. PLoS One (2013) 0.93
Kinesin molecular motor Eg5 functions during polypeptide synthesis. Mol Biol Cell (2011) 0.92
PKCα binds G3BP2 and regulates stress granule formation following cellular stress. PLoS One (2012) 0.92
Mechanistic insights into mammalian stress granule dynamics. J Cell Biol (2016) 0.91
Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation. PLoS Pathog (2015) 0.91
Sam68 relocalization into stress granules in response to oxidative stress through complexing with TIA-1. Exp Cell Res (2009) 0.91
The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA. Nucleic Acids Res (2013) 0.89
HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNA. Nat Commun (2013) 0.88
G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. J Cell Biol (2016) 0.88
Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs. Nucleic Acids Res (2013) 0.87
eEF2 and Ras-GAP SH3 domain-binding protein (G3BP1) modulate stress granule assembly during HIV-1 infection. Nat Commun (2014) 0.87
Stress granules in the viral replication cycle. Viruses (2011) 0.87
Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation. J Virol (2012) 0.86
Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B. RNA (2011) 0.85
G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA. J Cell Biol (2015) 0.85
Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS? Front Cell Neurosci (2015) 0.84
Could stress granules be involved in age-related diseases? Aging (Albany NY) (2009) 0.84
Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents. Bioorg Med Chem (2013) 0.84
The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response. Am J Physiol Cell Physiol (2009) 0.82
Garbled messages and corrupted translations. Nat Chem Biol (2010) 0.82
5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Res (2014) 0.82
TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis. Nat Commun (2016) 0.81
The role of molecular microtubule motors and the microtubule cytoskeleton in stress granule dynamics. Int J Cell Biol (2011) 0.81
Characterization of fragile X mental retardation protein recruitment and dynamics in Drosophila stress granules. PLoS One (2013) 0.81
Amino acids 78 and 79 of Mammalian Orthoreovirus protein µNS are necessary for stress granule localization, core protein λ2 interaction, and de novo virus replication. Virology (2013) 0.80
Translational dysregulation by Pateamine A. Chem Biol (2007) 0.79
The translational repressor eIF4E-binding protein 2 (4E-BP2) correlates with selective delayed neuronal death after ischemia. J Cereb Blood Flow Metab (2013) 0.79
Cytoplasmic RNA Granules and Viral Infection. Annu Rev Virol (2014) 0.79
RNA binding proteins and the genesis of neurodegenerative diseases. Adv Exp Med Biol (2015) 0.78
A murine retrovirus co-Opts YB-1, a translational regulator and stress granule-associated protein, to facilitate virus assembly. J Virol (2014) 0.78
Staufen1 impairs stress granule formation in skeletal muscle cells from myotonic dystrophy type 1 patients. Mol Biol Cell (2016) 0.77
Who Regulates Whom? An Overview of RNA Granules and Viral Infections. Viruses (2016) 0.77
UVC-induced stress granules in mammalian cells. PLoS One (2014) 0.76
Enterovirus Control of Translation and RNA Granule Stress Responses. Viruses (2016) 0.76
DDX3 Interacts with Influenza A Virus NS1 and NP Proteins and Exerts Antiviral Function through Regulation of Stress Granule Formation. J Virol (2016) 0.76
Stress Granules and Virus Replication. Future Virol (2015) 0.75
Distinct recruitment of human eIF4E isoforms to processing bodies and stress granules. BMC Mol Biol (2016) 0.75
Synthesis of a simplified triazole analogue of pateamine A. Org Biomol Chem (2016) 0.75
Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance. Oncotarget (2016) 0.75
Movements of HIV-1 genomic RNA-APOBEC3F complexes and PKR reveal cytoplasmic and nuclear PKR defenses and HIV-1 evasion strategies. Virus Res (2015) 0.75
Herpes Simplex Virus 2 Virion Host Shutoff Endoribonuclease Activity Is Required To Disrupt Stress Granule Formation. J Virol (2016) 0.75
Casein Kinase 2 is linked to stress granule dynamics through phosphorylation of the stress granule nucleating protein G3BP1. Mol Cell Biol (2016) 0.75
Stress-specific differences in assembly and composition of stress granules and related foci. J Cell Sci (2017) 0.75
Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses. PLoS Pathog (2016) 0.75
Stress granule induction after brain ischemia is independent of eukaryotic translation initiation factor (eIF) 2α phosphorylation and is correlated with a decrease in eIF4B and eIF4E proteins. J Biol Chem (2016) 0.75
Sumoylation of eIF4A2 affects stress granule formation. J Cell Sci (2016) 0.75
Alphaherpesvirus Subversion of Stress-Induced Translational Arrest. Viruses (2016) 0.75
Disruption of Stress Granule Formation by the Multifunctional Cricket Paralysis Virus 1A Protein. J Virol (2017) 0.75
Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chem Biol (2017) 0.75
Zika virus inhibits eIF2α-dependent stress granule assembly. PLoS Negl Trop Dis (2017) 0.75
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science (2004) 11.39
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J Cell Biol (2005) 9.25
RNA granules. J Cell Biol (2006) 7.79
Stress granules: the Tao of RNA triage. Trends Biochem Sci (2008) 6.27
Stress granule assembly is mediated by prion-like aggregation of TIA-1. Mol Biol Cell (2004) 6.04
Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell (2007) 5.29
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell (2009) 5.22
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell (2002) 5.20
Identification of a target RNA motif for RNA-binding protein HuR. Proc Natl Acad Sci U S A (2004) 5.15
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proc Natl Acad Sci U S A (2008) 4.80
Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth. Proc Natl Acad Sci U S A (2008) 4.79
Mammalian stress granules and processing bodies. Methods Enzymol (2007) 4.76
RNA granules: post-transcriptional and epigenetic modulators of gene expression. Nat Rev Mol Cell Biol (2009) 4.57
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J (2004) 4.45
HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev (2009) 4.41
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc Natl Acad Sci U S A (2003) 4.34
Stressful initiations. J Cell Sci (2002) 4.31
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev (2012) 4.19
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J (2004) 4.08
Angiogenin cleaves tRNA and promotes stress-induced translational repression. J Cell Biol (2009) 4.07
LincRNA-p21 suppresses target mRNA translation. Mol Cell (2012) 3.87
Global analysis of stress-regulated mRNA turnover by using cDNA arrays. Proc Natl Acad Sci U S A (2002) 3.71
eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell (2007) 3.46
Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol (2010) 3.44
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell (2010) 3.27
Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell (2011) 3.23
AGEMAP: a gene expression database for aging in mice. PLoS Genet (2007) 3.22
The HBV drug entecavir - effects on HIV-1 replication and resistance. N Engl J Med (2007) 3.20
Smartphone medication adherence apps: potential benefits to patients and providers. J Am Pharm Assoc (2003) (2013) 3.13
p16(INK4a) translation suppressed by miR-24. PLoS One (2008) 3.08
ARE-mRNA degradation requires the 5'-3' decay pathway. EMBO Rep (2006) 3.01
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure. J Biol Chem (2005) 2.85
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. Mol Cell Biol (2005) 2.83
A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment. Cancer Discov (2011) 2.77
A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nat Cell Biol (2008) 2.76
Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (2009) 2.76
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci U S A (2008) 2.76
Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. J Clin Invest (2009) 2.75
A clinical drug library screen identifies astemizole as an antimalarial agent. Nat Chem Biol (2006) 2.72
Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation. Cell Stress Chaperones (2002) 2.70
Role of the RNA-binding protein HuR in colon carcinogenesis. Oncogene (2003) 2.69
miR-519 suppresses tumor growth by reducing HuR levels. Cell Cycle (2010) 2.63
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem (2010) 2.61
Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem (2008) 2.60
Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip Rev RNA (2010) 2.59
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet (2013) 2.59
Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell (2010) 2.54
Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir. J Natl Cancer Inst (2012) 2.47
Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin. J Biol Chem (2008) 2.38
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling. J Biol Chem (2003) 2.38
HuR: post-transcriptional paths to malignancy. RNA Biol (2005) 2.38
The subaxial cervical spine injury classification system: a novel approach to recognize the importance of morphology, neurology, and integrity of the disco-ligamentous complex. Spine (Phila Pa 1976) (2007) 2.37
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha. EMBO J (2005) 2.33
Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization. Proc Natl Acad Sci U S A (2009) 2.33
Guar seed beta-mannan synthase is a member of the cellulose synthase super gene family. Science (2004) 2.31
miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. Proc Natl Acad Sci U S A (2008) 2.29
HuR as a negative posttranscriptional modulator in inflammation. Mol Cell (2005) 2.27
Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Mol Biol Cell (2005) 2.27
MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90. Mol Cell Biol (2008) 2.26
Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle (2007) 2.25
Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs. Mol Cell Biol (2007) 2.24
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Mol Cell Biol (2007) 2.20
Knockout mice lacking steroidogenic factor 1 are a novel genetic model of hypothalamic obesity. Endocrinology (2002) 2.19
Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability. BMC Genomics (2005) 2.18
Inhibition of eukaryotic translation initiation by the marine natural product pateamine A. Mol Cell (2005) 2.17
Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev (2008) 2.14
AMP-activated kinase regulates cytoplasmic HuR. Mol Cell Biol (2002) 2.14
GU-rich RNA: expanding CUGBP1 function, broadening mRNA turnover. Mol Cell (2008) 2.08
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J Biol Chem (2003) 2.06
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. Mol Cell Biol (2006) 2.05
Stress granules and cell signaling: more than just a passing phase? Trends Biochem Sci (2013) 2.01
Inhibition of angiogenesis by the antifungal drug itraconazole. ACS Chem Biol (2007) 2.00
Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron (2004) 1.99
Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs. Sci Signal (2009) 1.97
Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells. Proc Natl Acad Sci U S A (2009) 1.95
Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function. J Biol Chem (2003) 1.95
Stress granules. Curr Biol (2009) 1.94
Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol (2003) 1.93
Reprogramming mRNA translation during stress. Curr Opin Cell Biol (2008) 1.92
microRNA expression patterns reveal differential expression of target genes with age. PLoS One (2010) 1.92
Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex. Cancer Res (2003) 1.91
XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nat Chem Biol (2011) 1.89
The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis. Cancer Res (2009) 1.88
Translational repression by RNA-binding protein TIAR. Mol Cell Biol (2006) 1.87
Posttranscriptional gene regulation by long noncoding RNA. J Mol Biol (2012) 1.87
HuR function in disease. Front Biosci (Landmark Ed) (2012) 1.86
Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines. Nucleic Acids Res (2009) 1.86
Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells. Mol Cell Biol (2003) 1.83
The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation. J Biol Chem (2008) 1.83
SRT1720 improves survival and healthspan of obese mice. Sci Rep (2011) 1.81
Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA. J Biol Chem (2006) 1.75
miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2010) 1.75