In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

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Published in Proc Natl Acad Sci U S A on June 25, 2008

Authors

David Plouffe1, Achim Brinker, Case McNamara, Kerstin Henson, Nobutaka Kato, Kelli Kuhen, Advait Nagle, Francisco Adrián, Jason T Matzen, Paul Anderson, Tae-Gyu Nam, Nathanael S Gray, Arnab Chatterjee, Jeff Janes, S Frank Yan, Richard Trager, Jeremy S Caldwell, Peter G Schultz, Yingyao Zhou, Elizabeth A Winzeler

Author Affiliations

1: Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.

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