Konrad Basler

Author PubWeight™ 121.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proc Natl Acad Sci U S A 2007 12.13
2 Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 2006 4.09
3 The many faces and functions of β-catenin. EMBO J 2012 3.85
4 Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol 2009 3.67
5 dMyc transforms cells into super-competitors. Cell 2004 3.66
6 Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell 2002 3.42
7 The Decapentaplegic morphogen gradient: from pattern formation to growth regulation. Nat Rev Genet 2007 3.04
8 Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature 2002 2.98
9 Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily. Curr Biol 2002 2.54
10 Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Cell 2006 2.47
11 Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat Cell Biol 2008 2.43
12 Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. PLoS Biol 2009 2.25
13 Transcription in the absence of histone H3.3. Curr Biol 2009 2.24
14 Transcription under the control of nuclear Arm/beta-catenin. Curr Biol 2006 2.11
15 Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and function. Genome Res 2009 1.83
16 Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell 2002 1.77
17 Model for the regulation of size in the wing imaginal disc of Drosophila. Mech Dev 2006 1.76
18 Wnt trafficking: new insights into Wnt maturation, secretion and spreading. Traffic 2010 1.60
19 A simple molecular complex mediates widespread BMP-induced repression during Drosophila development. Dev Cell 2004 1.60
20 Exploring the effects of mechanical feedback on epithelial topology. Development 2010 1.59
21 Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. Cell 2003 1.58
22 Porcupine-mediated lipidation is required for Wnt recognition by Wls. Dev Biol 2011 1.51
23 A universal method for automated gene mapping. Genome Biol 2005 1.50
24 Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin. Curr Biol 2005 1.50
25 Wingful, an extracellular feedback inhibitor of Wingless. Genes Dev 2002 1.48
26 Helping Wingless take flight: how WNT proteins are secreted. Nat Rev Mol Cell Biol 2007 1.42
27 Refined LexA transactivators and their use in combination with the Drosophila Gal4 system. Proc Natl Acad Sci U S A 2010 1.31
28 Dissecting nuclear Wingless signalling: recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins. Mech Dev 2005 1.29
29 A screen for genes expressed in Drosophila imaginal discs. Int J Dev Biol 2002 1.29
30 Generating and navigating proteome maps using mass spectrometry. Nat Rev Mol Cell Biol 2010 1.29
31 Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. Cancer Res 2010 1.28
32 Regulation of organ growth by morphogen gradients. Cold Spring Harb Perspect Biol 2010 1.28
33 A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila. Development 2013 1.25
34 Recombinases and their use in gene activation, gene inactivation, and transgenesis. Methods Mol Biol 2008 1.21
35 Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size. Development 2012 1.20
36 WNT secretion and signalling in human disease. Trends Mol Med 2012 1.19
37 Probing transcription-specific outputs of β-catenin in vivo. Genes Dev 2011 1.18
38 Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels. Development 2008 1.14
39 Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. EMBO J 2008 1.12
40 A genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved component. Genetics 2005 1.09
41 A genetic screen for hedgehog targets involved in the maintenance of the Drosophila anteroposterior compartment boundary. Genetics 2003 1.07
42 Identification and in vivo role of the Armadillo-Legless interaction. Development 2004 1.06
43 Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation. Dev Cell 2011 1.04
44 Formation of the long range Dpp morphogen gradient. PLoS Biol 2011 1.03
45 The hedgehog signaling pathway: where did it come from? PLoS Biol 2009 1.02
46 Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells. EMBO J 2010 1.02
47 A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion. EMBO Rep 2011 1.02
48 A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK. PLoS One 2009 1.02
49 Requirement for Pangolin/dTCF in Drosophila Wingless signaling. Proc Natl Acad Sci U S A 2003 1.01
50 Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. Int J Dev Biol 2002 1.00
51 A high-throughput template for optimizing Drosophila organ culture with response-surface methods. Development 2013 0.99
52 The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway. EMBO Rep 2009 0.99
53 Signal-induced repression: the exception or the rule in developmental signaling? Dev Cell 2008 0.98
54 The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control. Mech Dev 2009 0.97
55 Transcription in the absence of histone H3.2 and H3K4 methylation. Curr Biol 2012 0.94
56 A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomics. Fly (Austin) 2007 0.94
57 BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling. Mech Dev 2006 0.93
58 Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. Dev Cell 2013 0.92
59 Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling. J Biol Chem 2011 0.92
60 Functional characterization of Drosophila microRNAs by a novel in vivo library. Genetics 2012 0.91
61 Comment on "Dynamics of dpp signaling and proliferation control". Science 2012 0.91
62 The PHD domain is required to link Drosophila Pygopus to Legless/beta-catenin and not to histone H3. Mech Dev 2009 0.90
63 Cell biology. Cytonemes show their colors. Science 2011 0.85
64 Structure-function analysis of Eiger, the Drosophila TNF homolog. Cell Res 2009 0.85
65 Cell-sorting at the A/P boundary in the Drosophila wing primordium: a computational model to consolidate observed non-local effects of Hh signaling. PLoS Comput Biol 2011 0.85
66 Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells. Stem Cells 2015 0.83
67 Sphingolipid depletion impairs endocytic traffic and inhibits Wingless signaling. Mech Dev 2013 0.81
68 Wnt lipid modifications: not as saturated as we thought. Dev Cell 2006 0.81
69 A reverse genetic screen in Drosophila using a deletion-inducing mutagen. Genome Biol 2004 0.80
70 Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling. Genes Dev 2010 0.80
71 Morphogen gradients: expand and repress. Curr Biol 2011 0.79
72 The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development 2013 0.79
73 Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients. PLoS One 2013 0.78
74 Multiorder correction algorithms to remove image distortions from mass spectrometry imaging data sets. Anal Chem 2013 0.77
75 Quantitative proteomics: a central technology for systems biology. J Proteomics 2009 0.77
76 Powerful Drosophila screens that paved the wingless pathway. Fly (Austin) 2015 0.76
77 A RING finger to wed TCF and β-catenin. EMBO Rep 2013 0.75
78 Confronting morphogen gradients: how important are they for growth? Sci Signal 2009 0.75
79 DIGESTIF: a universal quality standard for the control of bottom-up proteomics experiments. J Proteome Res 2014 0.75