The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMC 2759729)

Published in EMBO Rep on August 28, 2009

Authors

Haiyun Song1, Chloe Spichiger-Haeusermann, Konrad Basler

Author Affiliations

1: Institute of Molecular Biology, University of Zurich, Zurich, Switzerland.

Articles citing this

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res (2011) 4.91

The many faces and functions of β-catenin. EMBO J (2012) 3.85

Trithorax group proteins: switching genes on and keeping them active. Nat Rev Mol Cell Biol (2011) 2.56

Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells. PLoS Genet (2015) 1.43

The nucleosome remodeling factor. FEBS Lett (2011) 1.08

Chromatin remodeling complex NURF regulates thymocyte maturation. Genes Dev (2011) 1.05

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. EMBO J (2014) 1.05

Chromatin dynamics: interplay between remodeling enzymes and histone modifications. Biochim Biophys Acta (2014) 1.04

NLP is a novel transcription regulator involved in VSG expression site control in Trypanosoma brucei. Nucleic Acids Res (2010) 0.96

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner. J Exp Med (2014) 0.91

A novel Pzg-NURF complex regulates Notch target gene activity. Mol Biol Cell (2010) 0.90

Soma influences GSC progeny differentiation via the cell adhesion-mediated steroid-let-7-Wingless signaling cascade that regulates chromatin dynamics. Biol Open (2015) 0.85

Nucleosome remodeler SNF2L suppresses cell proliferation and migration and attenuates Wnt signaling. Mol Cell Biol (2012) 0.83

ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells. J Clin Invest (2015) 0.83

Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling. Genes Dev (2010) 0.80

On the way of revealing coactivator complexes cross-talk during transcriptional activation. Cell Biosci (2016) 0.76

Long noncoding RNA lncKdm2b is required for ILC3 maintenance by initiation of Zfp292 expression. Nat Immunol (2017) 0.75

Expansion of the ISWI chromatin remodeler family with new active complexes. EMBO Rep (2017) 0.75

Articles cited by this

beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J (1997) 12.97

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature (2006) 10.73

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. Science (2000) 7.25

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev (2006) 3.85

The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J (2000) 3.77

The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo. Mol Cell (2000) 3.62

ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor. Cell (1995) 3.44

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell (2002) 3.42

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature (1997) 3.15

The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression. J Cell Biol (2000) 3.13

The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation. EMBO J (2001) 2.87

Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions. Mol Cell (2001) 2.68

TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila. Nature (2002) 2.48

Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Cell (2006) 2.47

Biological functions of the ISWI chromatin remodeling complex NURF. Genes Dev (2002) 2.37

naked cuticle encodes an inducible antagonist of Wnt signalling. Nature (2000) 2.35

Transcription under the control of nuclear Arm/beta-catenin. Curr Biol (2006) 2.11

Negative regulation of Armadillo, a Wingless effector in Drosophila. Development (1997) 2.09

Acf1 confers unique activities to ACF/CHRAC and promotes the formation rather than disruption of chromatin in vivo. Genes Dev (2004) 2.01

C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J (2006) 2.01

Nucleosome mobilization and positioning by ISWI-containing chromatin-remodeling factors. J Cell Sci (2001) 2.00

Distinct strategies to make nucleosomal DNA accessible. Mol Cell (2003) 1.96

ISWI induces nucleosome sliding on nicked DNA. Mol Cell (2001) 1.78

The Drosophila BRM complex facilitates global transcription by RNA polymerase II. EMBO J (2002) 1.78

Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development. Development (2003) 1.72

The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis. Genes Dev (2005) 1.60

Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin. Curr Biol (2005) 1.50

Novel TCF-binding sites specify transcriptional repression by Wnt signalling. EMBO J (2008) 1.48

ATP-dependent chromatin remodeling enzymes: two heads are not better, just different. Curr Opin Genet Dev (2008) 1.33

A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes. Curr Biol (2004) 1.07

Identification and in vivo role of the Armadillo-Legless interaction. Development (2004) 1.06

The chromatin remodelers ISWI and ACF1 directly repress Wingless transcriptional targets. Dev Biol (2008) 1.00

The Wingless target gene Dfz3 encodes a new member of the Drosophila Frizzled family. Mech Dev (2000) 0.99

Regulation of the feedback antagonist naked cuticle by Wingless signaling. Dev Biol (2008) 0.93

Articles by these authors

An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proc Natl Acad Sci U S A (2007) 12.13

Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell (2006) 4.09

The many faces and functions of β-catenin. EMBO J (2012) 3.85

Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol (2009) 3.67

dMyc transforms cells into super-competitors. Cell (2004) 3.66

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell (2002) 3.42

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation. Nat Rev Genet (2007) 3.04

Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature (2002) 2.98

Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily. Curr Biol (2002) 2.54

Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Cell (2006) 2.47

Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat Cell Biol (2008) 2.43

Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. PLoS Biol (2009) 2.25

Transcription in the absence of histone H3.3. Curr Biol (2009) 2.24

Transcription under the control of nuclear Arm/beta-catenin. Curr Biol (2006) 2.11

Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and function. Genome Res (2009) 1.83

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell (2002) 1.77

Model for the regulation of size in the wing imaginal disc of Drosophila. Mech Dev (2006) 1.76

A simple molecular complex mediates widespread BMP-induced repression during Drosophila development. Dev Cell (2004) 1.60

Wnt trafficking: new insights into Wnt maturation, secretion and spreading. Traffic (2010) 1.60

Exploring the effects of mechanical feedback on epithelial topology. Development (2010) 1.59

Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. Cell (2003) 1.58

Porcupine-mediated lipidation is required for Wnt recognition by Wls. Dev Biol (2011) 1.51

A universal method for automated gene mapping. Genome Biol (2005) 1.50

Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin. Curr Biol (2005) 1.50

Wingful, an extracellular feedback inhibitor of Wingless. Genes Dev (2002) 1.48

Helping Wingless take flight: how WNT proteins are secreted. Nat Rev Mol Cell Biol (2007) 1.42

Refined LexA transactivators and their use in combination with the Drosophila Gal4 system. Proc Natl Acad Sci U S A (2010) 1.31

Dissecting nuclear Wingless signalling: recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins. Mech Dev (2005) 1.29

A screen for genes expressed in Drosophila imaginal discs. Int J Dev Biol (2002) 1.29

Generating and navigating proteome maps using mass spectrometry. Nat Rev Mol Cell Biol (2010) 1.29

Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. Cancer Res (2010) 1.28

Regulation of organ growth by morphogen gradients. Cold Spring Harb Perspect Biol (2010) 1.28

A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila. Development (2013) 1.25

Recombinases and their use in gene activation, gene inactivation, and transgenesis. Methods Mol Biol (2008) 1.21

Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size. Development (2012) 1.20

WNT secretion and signalling in human disease. Trends Mol Med (2012) 1.19

Probing transcription-specific outputs of β-catenin in vivo. Genes Dev (2011) 1.18

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels. Development (2008) 1.14

Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. EMBO J (2008) 1.12

A genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved component. Genetics (2005) 1.09

A genetic screen for hedgehog targets involved in the maintenance of the Drosophila anteroposterior compartment boundary. Genetics (2003) 1.07

Identification and in vivo role of the Armadillo-Legless interaction. Development (2004) 1.06

Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation. Dev Cell (2011) 1.04

Formation of the long range Dpp morphogen gradient. PLoS Biol (2011) 1.03

The hedgehog signaling pathway: where did it come from? PLoS Biol (2009) 1.02

A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion. EMBO Rep (2011) 1.02

A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK. PLoS One (2009) 1.02

Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells. EMBO J (2010) 1.02

Requirement for Pangolin/dTCF in Drosophila Wingless signaling. Proc Natl Acad Sci U S A (2003) 1.01

Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. Int J Dev Biol (2002) 1.00

A high-throughput template for optimizing Drosophila organ culture with response-surface methods. Development (2013) 0.99

Signal-induced repression: the exception or the rule in developmental signaling? Dev Cell (2008) 0.98

The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control. Mech Dev (2009) 0.97

A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomics. Fly (Austin) (2007) 0.94

Transcription in the absence of histone H3.2 and H3K4 methylation. Curr Biol (2012) 0.94

BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling. Mech Dev (2006) 0.93

Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. Dev Cell (2013) 0.92

Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling. J Biol Chem (2011) 0.92

Functional characterization of Drosophila microRNAs by a novel in vivo library. Genetics (2012) 0.91

Comment on "Dynamics of dpp signaling and proliferation control". Science (2012) 0.91

The PHD domain is required to link Drosophila Pygopus to Legless/beta-catenin and not to histone H3. Mech Dev (2009) 0.90

Structure-function analysis of Eiger, the Drosophila TNF homolog. Cell Res (2009) 0.85

Cell biology. Cytonemes show their colors. Science (2011) 0.85

Cell-sorting at the A/P boundary in the Drosophila wing primordium: a computational model to consolidate observed non-local effects of Hh signaling. PLoS Comput Biol (2011) 0.85

Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells. Stem Cells (2015) 0.83

Wnt lipid modifications: not as saturated as we thought. Dev Cell (2006) 0.81

Sphingolipid depletion impairs endocytic traffic and inhibits Wingless signaling. Mech Dev (2013) 0.81

Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling. Genes Dev (2010) 0.80

A reverse genetic screen in Drosophila using a deletion-inducing mutagen. Genome Biol (2004) 0.80

Morphogen gradients: expand and repress. Curr Biol (2011) 0.79

The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development (2013) 0.79

Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients. PLoS One (2013) 0.78

Quantitative proteomics: a central technology for systems biology. J Proteomics (2009) 0.77

Multiorder correction algorithms to remove image distortions from mass spectrometry imaging data sets. Anal Chem (2013) 0.77

Powerful Drosophila screens that paved the wingless pathway. Fly (Austin) (2015) 0.76

A RING finger to wed TCF and β-catenin. EMBO Rep (2013) 0.75

Confronting morphogen gradients: how important are they for growth? Sci Signal (2009) 0.75

DIGESTIF: a universal quality standard for the control of bottom-up proteomics experiments. J Proteome Res (2014) 0.75