Published in Mech Dev on December 29, 2006
Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol (2012) 3.07
A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element. Nat Genet (2014) 2.94
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Morphogen control of wing growth through the Fat signaling pathway. Dev Cell (2008) 2.80
Cytoskeletal tension inhibits Hippo signaling through an Ajuba-Warts complex. Cell (2014) 1.98
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Regulatory role of cell division rules on tissue growth heterogeneity. Front Plant Sci (2012) 1.01
Regulation of cell shape, wing hair initiation and the actin cytoskeleton by Trc/Fry and Wts/Mats complexes. Dev Biol (2010) 1.00
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Mechanical force sensing in tissues. Prog Mol Biol Transl Sci (2014) 0.89
The Spectrin cytoskeleton regulates the Hippo signalling pathway. EMBO J (2015) 0.87
In-vivo imaging of the Drosophila wing imaginal disc over time: novel insights on growth and boundary formation. PLoS One (2012) 0.87
Incorporating chemical signalling factors into cell-based models of growing epithelial tissues. J Math Biol (2011) 0.86
Regulation of BMP activity and range in Drosophila wing development. Curr Opin Cell Biol (2011) 0.86
Mechanical stress contributes to the expression of the STM homeobox gene in Arabidopsis shoot meristems. Elife (2015) 0.85
Cell-sorting at the A/P boundary in the Drosophila wing primordium: a computational model to consolidate observed non-local effects of Hh signaling. PLoS Comput Biol (2011) 0.85
Mechanical control of organ size in the development of the Drosophila wing disc. PLoS One (2013) 0.84
Mechanisms of regulating tissue elongation in Drosophila wing: impact of oriented cell divisions, oriented mechanical forces, and reduced cell size. PLoS One (2014) 0.83
The role of mathematical models in understanding pattern formation in developmental biology. Bull Math Biol (2014) 0.83
Mesenchymal morphogenesis of embryonic stem cells dynamically modulates the biophysical microtissue niche. Sci Rep (2014) 0.82
Mechanical forces mediate localized topological change in epithelia. Conf Proc IEEE Eng Med Biol Soc (2011) 0.81
Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper. Biol Open (2015) 0.81
Photo-elastic properties of the wing imaginal disc of Drosophila. Eur Phys J E Soft Matter (2010) 0.80
Dynamics and mechanical stability of the developing dorsoventral organizer of the wing imaginal disc. PLoS Comput Biol (2011) 0.80
Differential growth triggers mechanical feedback that elevates Hippo signaling. Proc Natl Acad Sci U S A (2016) 0.79
Cellular morphogenesis in silico. Biophys J (2009) 0.79
Comparing individual-based approaches to modelling the self-organization of multicellular tissues. PLoS Comput Biol (2017) 0.79
Bulk elastic properties of chicken embryos during somitogenesis. Biomed Eng Online (2010) 0.79
Vertex models: from cell mechanics to tissue morphogenesis. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
How does a single cell know when the liver has reached its correct size? PLoS One (2014) 0.77
Growth of the eye lens: II. Allometric studies. Mol Vis (2014) 0.76
YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage. Bioessays (2016) 0.76
BMP signaling in wing development: A critical perspective on quantitative image analysis. FEBS Lett (2012) 0.76
Cellular and molecular drivers of differential organ growth: insights from the limbs of Monodelphis domestica. Dev Genes Evol (2016) 0.76
An Unbiased Analysis of Candidate Mechanisms for the Regulation of Drosophila Wing Disc Growth. Sci Rep (2016) 0.75
Mechanobiological induction of long-range contractility by diffusing biomolecules and size scaling in cell assemblies. Sci Rep (2016) 0.75
Expanding signaling-molecule wavefront model of cell polarization in the Drosophila wing primordium. PLoS Comput Biol (2017) 0.75
An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proc Natl Acad Sci U S A (2007) 12.13
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev (2004) 7.51
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Mol Cell (2003) 6.76
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc Natl Acad Sci U S A (2005) 5.34
Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Curr Biol (2002) 5.12
Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry. Genome Biol (2004) 4.91
The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J Biol (2003) 4.85
Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science (2004) 4.70
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol (2003) 4.67
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nat Cell Biol (2003) 4.20
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell (2006) 4.09
The many faces and functions of β-catenin. EMBO J (2012) 3.85
The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics (2004) 3.71
Dietary restriction in long-lived dwarf flies. Science (2002) 3.71
Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol (2009) 3.67
dMyc transforms cells into super-competitors. Cell (2004) 3.66
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev (2004) 3.59
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell (2002) 3.42
A high-quality catalog of the Drosophila melanogaster proteome. Nat Biotechnol (2007) 3.34
The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. Genetics (2007) 3.08
The Decapentaplegic morphogen gradient: from pattern formation to growth regulation. Nat Rev Genet (2007) 3.04
Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature (2002) 2.98
Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily. Curr Biol (2002) 2.54
Drosophila egg-laying site selection as a system to study simple decision-making processes. Science (2008) 2.50
Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Cell (2006) 2.47
Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat Cell Biol (2008) 2.43
The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell (2010) 2.34
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1. Nat Cell Biol (2002) 2.31
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. PLoS Biol (2009) 2.25
Transcription in the absence of histone H3.3. Curr Biol (2009) 2.24
Transcription under the control of nuclear Arm/beta-catenin. Curr Biol (2006) 2.11
Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB. Science (2002) 2.05
A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Mol Cell Proteomics (2005) 1.95
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS One (2008) 1.95
Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and function. Genome Res (2009) 1.83
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell (2002) 1.77
Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance. J Biol (2008) 1.65
Wnt trafficking: new insights into Wnt maturation, secretion and spreading. Traffic (2010) 1.60
A simple molecular complex mediates widespread BMP-induced repression during Drosophila development. Dev Cell (2004) 1.60
The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development (2002) 1.60
Exploring the effects of mechanical feedback on epithelial topology. Development (2010) 1.59
Conversion of an extracellular Dpp/BMP morphogen gradient into an inverse transcriptional gradient. Cell (2003) 1.58
Porcupine-mediated lipidation is required for Wnt recognition by Wls. Dev Biol (2011) 1.51
A universal method for automated gene mapping. Genome Biol (2005) 1.50
Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin. Curr Biol (2005) 1.50
Scattered light fluorescence microscopy: imaging through turbid layers. Opt Lett (2010) 1.49
Wingful, an extracellular feedback inhibitor of Wingless. Genes Dev (2002) 1.48
Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. Dev Biol (2006) 1.43
Helping Wingless take flight: how WNT proteins are secreted. Nat Rev Mol Cell Biol (2007) 1.42
Model for the robust establishment of precise proportions in the early Drosophila embryo. J Theor Biol (2005) 1.35
Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. EMBO J (2003) 1.33
Refined LexA transactivators and their use in combination with the Drosophila Gal4 system. Proc Natl Acad Sci U S A (2010) 1.31
Dissecting nuclear Wingless signalling: recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins. Mech Dev (2005) 1.29
A screen for genes expressed in Drosophila imaginal discs. Int J Dev Biol (2002) 1.29
Generating and navigating proteome maps using mass spectrometry. Nat Rev Mol Cell Biol (2010) 1.29
Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. Cancer Res (2010) 1.28
Regulation of organ growth by morphogen gradients. Cold Spring Harb Perspect Biol (2010) 1.28
Substrate-dependent control of MAPK phosphorylation in vivo. Mol Syst Biol (2011) 1.26
The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growth. EMBO J (2005) 1.25
A versatile platform for creating a comprehensive UAS-ORFeome library in Drosophila. Development (2013) 1.25
Recombinases and their use in gene activation, gene inactivation, and transgenesis. Methods Mol Biol (2008) 1.21
Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size. Development (2012) 1.20
WNT secretion and signalling in human disease. Trends Mol Med (2012) 1.19
Probing transcription-specific outputs of β-catenin in vivo. Genes Dev (2011) 1.18
The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway. PLoS Genet (2009) 1.17
Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels. Development (2008) 1.14
Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E. Curr Biol (2005) 1.14
Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome. Mol Syst Biol (2011) 1.12
Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. EMBO J (2008) 1.12
A genetic screen targeting the tumor necrosis factor/Eiger signaling pathway: identification of Drosophila TAB2 as a functionally conserved component. Genetics (2005) 1.09
A genetic screen for hedgehog targets involved in the maintenance of the Drosophila anteroposterior compartment boundary. Genetics (2003) 1.07
Determination of mechanical stress distribution in Drosophila wing discs using photoelasticity. Mech Dev (2009) 1.07
Identification and in vivo role of the Armadillo-Legless interaction. Development (2004) 1.06
The Drosophila melanogaster PeptideAtlas facilitates the use of peptide data for improved fly proteomics and genome annotation. BMC Bioinformatics (2009) 1.06
Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation. Dev Cell (2011) 1.04
Formation of the long range Dpp morphogen gradient. PLoS Biol (2011) 1.03
The hedgehog signaling pathway: where did it come from? PLoS Biol (2009) 1.02
A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK. PLoS One (2009) 1.02
A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion. EMBO Rep (2011) 1.02
Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells. EMBO J (2010) 1.02
Biochemical membrane lipidomics during Drosophila development. Dev Cell (2012) 1.02
Requirement for Pangolin/dTCF in Drosophila Wingless signaling. Proc Natl Acad Sci U S A (2003) 1.01
Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. PLoS Genet (2010) 1.01
MK2-dependent p38b signalling protects Drosophila hindgut enterocytes against JNK-induced apoptosis under chronic stress. PLoS Genet (2011) 1.00
The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER. Development (2003) 1.00
A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila. Autophagy (2009) 1.00
Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. Int J Dev Biol (2002) 1.00
A high-throughput template for optimizing Drosophila organ culture with response-surface methods. Development (2013) 0.99
The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway. EMBO Rep (2009) 0.99
Signal-induced repression: the exception or the rule in developmental signaling? Dev Cell (2008) 0.98
High-resolution SNP mapping by denaturing HPLC. Proc Natl Acad Sci U S A (2002) 0.97
The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control. Mech Dev (2009) 0.97
A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomics. Fly (Austin) (2007) 0.94
Transcription in the absence of histone H3.2 and H3K4 methylation. Curr Biol (2012) 0.94