Published in Structure on February 01, 2005
Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc Natl Acad Sci U S A (2012) 2.69
Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker. J Virol (2006) 1.58
Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. J Mol Biol (2007) 1.42
Restraining the conformation of HIV-1 gp120 by removing a flexible loop. EMBO J (2006) 1.41
Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS. Retrovirology (2007) 1.41
Coevolution Analysis of HIV-1 Envelope Glycoprotein Complex. PLoS One (2015) 1.39
HIV-1 envelope subregion length variation during disease progression. PLoS Pathog (2010) 1.20
Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein. J Mol Biol (2008) 1.14
Refinement of docked protein-ligand and protein-DNA structures using low frequency normal mode amplitude optimization. Nucleic Acids Res (2005) 1.11
Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope. Antimicrob Agents Chemother (2010) 1.05
Proximal glycans outside of the epitopes regulate the presentation of HIV-1 envelope gp120 helper epitopes. J Immunol (2009) 1.02
Truncation of the membrane-spanning domain of human immunodeficiency virus type 1 envelope glycoprotein defines elements required for fusion, incorporation, and infectivity. J Virol (2009) 1.02
Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization. J Biol Chem (2010) 1.01
Structure-based vaccine design in HIV: blind men and the elephant? Curr Pharm Des (2010) 0.99
Identification of two N-linked glycosylation sites within the core of the simian immunodeficiency virus glycoprotein whose removal enhances sensitivity to soluble CD4. J Virol (2005) 0.99
Structural improvement of unliganded simian immunodeficiency virus gp120 core by normal-mode-based X-ray crystallographic refinement. Acta Crystallogr D Biol Crystallogr (2009) 0.98
Model-building strategies for low-resolution X-ray crystallographic data. Acta Crystallogr D Biol Crystallogr (2009) 0.96
Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution. J Biol Chem (2010) 0.95
Crystal structure of a novel non-Pfam protein PF2046 solved using low resolution B-factor sharpening and multi-crystal averaging methods. Protein Cell (2010) 0.95
Structure of the 12-subunit RNA polymerase II refined with the aid of anomalous diffraction data. J Biol Chem (2009) 0.92
All-atom models of the membrane-spanning domain of HIV-1 gp41 from metadynamics. Biophys J (2010) 0.90
Low-resolution crystallography is coming of age. Structure (2005) 0.88
Structural plasticity of the Semliki Forest virus glycome upon interspecies transmission. J Proteome Res (2014) 0.85
A twin-cysteine motif in the V2 region of gp120 is associated with SIV envelope trimer stabilization. PLoS One (2013) 0.83
Residues in the membrane-spanning domain core modulate conformation and fusogenicity of the HIV-1 envelope glycoprotein. Virology (2010) 0.83
Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology (2014) 0.81
Developments in low-resolution biological X-ray crystallography. F1000 Biol Rep (2010) 0.78
The continuing HIV vaccine saga: naked emperors alongside fairy godmothers. Med Immunol (2005) 0.77
Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission. PLoS One (2015) 0.76
Structure and Glycan Binding of a New Cyanovirin-N Homolog. J Biol Chem (2016) 0.75
Ab initio phasing by molecular averaging in real space with new criteria: application to structure determination of a betanodavirus. Acta Crystallogr D Struct Biol (2016) 0.75
X-ray structure of a protein-conducting channel. Nature (2003) 9.20
Structure of an unliganded simian immunodeficiency virus gp120 core. Nature (2005) 8.30
Structure of the dengue virus envelope protein after membrane fusion. Nature (2004) 7.97
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science (2011) 7.86
A ligand-binding pocket in the dengue virus envelope glycoprotein. Proc Natl Acad Sci U S A (2003) 7.76
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. Nature (2006) 7.56
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc Natl Acad Sci U S A (2004) 7.55
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature (2006) 6.00
Crystal structure of glycoprotein B from herpes simplex virus 1. Science (2006) 5.57
Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature (2005) 5.44
Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction. Proc Natl Acad Sci U S A (2008) 5.33
Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science (2005) 4.97
The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol (2005) 4.81
The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nat Struct Mol Biol (2006) 4.62
Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature (2004) 4.48
An atomic model of the interferon-beta enhanceosome. Cell (2007) 4.22
Structure and function of an essential component of the outer membrane protein assembly machine. Science (2007) 3.85
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature (2008) 3.79
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nat Biotechnol (2012) 3.69
Structure of the human transferrin receptor-transferrin complex. Cell (2004) 3.64
Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. J Virol (2005) 3.58
Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. Proc Natl Acad Sci U S A (2011) 3.51
XMAP215 is a processive microtubule polymerase. Cell (2008) 3.33
Role of HIV membrane in neutralization by two broadly neutralizing antibodies. Proc Natl Acad Sci U S A (2009) 3.19
Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. Proc Natl Acad Sci U S A (2004) 3.10
Molecular organization of the Ndc80 complex, an essential kinetochore component. Proc Natl Acad Sci U S A (2005) 3.01
Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry. EMBO J (2005) 2.95
Beam-induced motion of vitrified specimen on holey carbon film. J Struct Biol (2012) 2.84
Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure (2012) 2.80
RNA synthesis in a cage--structural studies of reovirus polymerase lambda3. Cell (2002) 2.74
H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes. EMBO J (2002) 2.69
Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc Natl Acad Sci U S A (2009) 2.65
Influenza hemagglutinin and neuraminidase membrane glycoproteins. J Biol Chem (2010) 2.65
Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion. Proc Natl Acad Sci U S A (2008) 2.58
Subunit interactions in bovine papillomavirus. Proc Natl Acad Sci U S A (2010) 2.51
Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy. Curr Opin Struct Biol (2011) 2.47
The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site. EMBO J (2002) 2.41
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. J Biol Chem (2005) 2.36
Receptor binding by an H7N9 influenza virus from humans. Nature (2013) 2.33
Single-particle kinetics of influenza virus membrane fusion. Proc Natl Acad Sci U S A (2008) 2.32
Crystal structure of the clathrin adaptor protein 1 core. Proc Natl Acad Sci U S A (2004) 2.28
Atomic model of the papillomavirus capsid. EMBO J (2002) 2.27
Structure of the reovirus membrane-penetration protein, Mu1, in a complex with is protector protein, Sigma3. Cell (2002) 2.24
Variation and infectivity neutralization in influenza. Immunology (2006) 2.23
X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus. Virology (2003) 2.23
Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin. Proc Natl Acad Sci U S A (2012) 2.18
Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol (2006) 2.17
Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1. Structure (2008) 2.13
Structural rearrangements in the membrane penetration protein of a non-enveloped virus. Nature (2004) 2.05
Structure-based analysis of the herpes simplex virus glycoprotein D binding site present on herpesvirus entry mediator HveA (HVEM). J Virol (2002) 2.03
How does radiation damage in protein crystals depend on X-ray dose? Structure (2003) 2.01
Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. EMBO J (2004) 2.01
Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1. Mol Cell (2002) 2.00
Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957. Proc Natl Acad Sci U S A (2009) 1.98
Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching. Nature (2011) 1.93
Genetics of influenza viruses. Annu Rev Genet (2002) 1.88
Recognition of the centromere-specific histone Cse4 by the chaperone Scm3. Proc Natl Acad Sci U S A (2011) 1.87
Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion. Virology (2007) 1.83
Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion. Proc Natl Acad Sci U S A (2006) 1.83
Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature (2004) 1.81
Atomic model of an infectious rotavirus particle. EMBO J (2010) 1.79
Structure-based mutagenesis of herpes simplex virus glycoprotein D defines three critical regions at the gD-HveA/HVEM binding interface. J Virol (2003) 1.78
Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain. Structure (2006) 1.76
Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin. Proc Natl Acad Sci U S A (2002) 1.75
Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. J Biol Chem (2007) 1.72
Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc Natl Acad Sci U S A (2012) 1.70
Influenza a viruses with mutations in the m1 helix six domain display a wide variety of morphological phenotypes. J Virol (2005) 1.67
Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science (2009) 1.66
X-ray crystal structure of the rotavirus inner capsid particle at 3.8 A resolution. J Mol Biol (2010) 1.61
Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction. J Mol Biol (2007) 1.60
Stu2p binds tubulin and undergoes an open-to-closed conformational change. J Cell Biol (2006) 1.57
Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding. Structure (2007) 1.54
Noble metals strip peptides from class II MHC proteins. Nat Chem Biol (2006) 1.53
Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution. Structure (2005) 1.53
The active conformation of the PAK1 kinase domain. Structure (2005) 1.50
The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell (2010) 1.48
Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell (2003) 1.48
CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule. Dev Cell (2010) 1.47
Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses. Nat Struct Mol Biol (2010) 1.46
Receptor binding by a ferret-transmissible H5 avian influenza virus. Nature (2013) 1.43
Restraining the conformation of HIV-1 gp120 by removing a flexible loop. EMBO J (2006) 1.41
Molecular structure, function, and dynamics of clathrin-mediated membrane traffic. Cold Spring Harb Perspect Biol (2014) 1.41
Differential roles of the fan-shaped body and the ellipsoid body in Drosophila visual pattern memory. Learn Mem (2009) 1.40
Potential nectin-1 binding site on herpes simplex virus glycoprotein d. J Virol (2005) 1.39
Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques. J Mol Biol (2005) 1.38
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint. Proc Natl Acad Sci U S A (2007) 1.35
Peptide inhibitors of dengue-virus entry target a late-stage fusion intermediate. PLoS Pathog (2010) 1.35
Protein arms in the kinetochore-microtubule interface of the yeast DASH complex. Mol Biol Cell (2007) 1.35
Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment. Virology (2002) 1.34
Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain. J Virol (2006) 1.34
Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates. Elife (2013) 1.31