Published in J Mol Biol on April 19, 2007
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NMR resonance assignments of the catalytic domain of human serine/threonine phosphatase calcineurin in unligated and PVIVIT-peptide-bound states. Biomol NMR Assign (2014) 0.75
Structure-based optimization of a peptidyl inhibitor against calcineurin-nuclear factor of activated T cell (NFAT) interaction. J Med Chem (2014) 0.75
Crystallization and preliminary crystallographic study of a trypsin-resistant catalytic domain of human calcineurin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.75
Direct evidence for calcineurin binding to the exon-7 loop of the sodium-bicarbonate cotransporter NBCn1. Int J Biol Sci (2014) 0.75
Investigating the human Calcineurin Interaction Network using the πɸLxVP SLiM. Sci Rep (2016) 0.75
Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization. PLoS One (2015) 0.75
The unique C-terminus of calcineurin isoform CNAβ1 confers non-canonical regulation of enzyme activity by Ca(2+) and calmodulin. J Biol Chem (2017) 0.75
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (2009) 32.97
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
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The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
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Crystal structure of glycoprotein B from herpes simplex virus 1. Science (2006) 5.57
Functional and evolutionary insights from the genomes of three parasitoid Nasonia species. Science (2010) 5.56
Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature (2005) 5.44
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Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science (2005) 4.97
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Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature (2004) 4.48
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol (2002) 4.38
An atomic model of the interferon-beta enhanceosome. Cell (2007) 4.22
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nat Immunol (2004) 4.21
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle (2009) 4.14
Transcriptional mechanisms underlying lymphocyte tolerance. Cell (2002) 4.04
Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature (2012) 4.00
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance. Nat Immunol (2008) 3.98
An epigenetic view of helper T cell differentiation. Nat Immunol (2003) 3.87
Biochemical and functional characterization of Orai proteins. J Biol Chem (2007) 3.87
Structure and function of an essential component of the outer membrane protein assembly machine. Science (2007) 3.85
B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nat Biotechnol (2012) 3.69
Structure of the human transferrin receptor-transferrin complex. Cell (2004) 3.64
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT. Nature (2006) 3.61
Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. J Virol (2005) 3.58
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature (2007) 3.55
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Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science (2009) 3.47
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Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL. Science (2008) 3.17
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Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc Natl Acad Sci U S A (2011) 3.07
The role of NFAT transcription factors in integrin-mediated carcinoma invasion. Nat Cell Biol (2002) 3.05
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STIM1 gates the store-operated calcium channel ORAI1 in vitro. Nat Struct Mol Biol (2009) 2.15