Published in J Immunol on April 15, 2005
CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J Exp Med (2007) 4.42
Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J Infect Dis (2010) 2.98
Epigenetic mechanisms of regulation of Foxp3 expression. Blood (2009) 2.27
A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory. EMBO J (2006) 1.71
Plasticity in programming of effector and memory CD8 T-cell formation. Immunol Rev (2010) 1.59
Programming CD8+ T cells for effective immunotherapy. Curr Opin Immunol (2006) 1.51
Interleukin 2 gene transcription is regulated by Ikaros-induced changes in histone acetylation in anergic T cells. Blood (2007) 1.43
Interleukin 2: from immunostimulation to immunoregulation and back again. EMBO Rep (2007) 1.31
Transcriptional regulation of IL-2 in health and autoimmunity. Autoimmun Rev (2008) 1.31
Demethylation of a specific hypersensitive site in the Th2 locus control region. Proc Natl Acad Sci U S A (2007) 1.27
Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem (2009) 1.13
The pharmacology of second-generation chimeric antigen receptors. Nat Rev Drug Discov (2015) 1.09
Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structure. J Immunol (2008) 1.07
Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states. J Biol Chem (2010) 1.06
Transcriptional regulation of T cell tolerance. Semin Immunol (2007) 1.00
Chromatin structure and gene regulation in T cell development and function. Curr Opin Immunol (2006) 0.99
Impaired CD4+ T-cell proliferation and effector function correlates with repressive histone methylation events in a mouse model of severe sepsis. Eur J Immunol (2010) 0.96
Nuclear factor Y is required for basal activation and chromatin accessibility of fibroblast growth factor receptor 2 promoter in osteoblast-like cells. J Biol Chem (2008) 0.95
De novo DNA methylation is required to restrict T helper lineage plasticity. J Biol Chem (2012) 0.94
Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus. J Biol Chem (2012) 0.93
Mbd2 promotes foxp3 demethylation and T-regulatory-cell function. Mol Cell Biol (2013) 0.92
Recent thymic emigrants and mature naive T cells exhibit differential DNA methylation at key cytokine loci. J Immunol (2013) 0.92
Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity. Blood (2013) 0.92
CD28 Costimulation: From Mechanism to Therapy. Immunity (2016) 0.90
Mechanisms behind functional avidity maturation in T cells. Clin Dev Immunol (2012) 0.90
Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis. Immunity (2016) 0.89
GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness. FEBS J (2010) 0.89
T cell immunity as a tool for studying epigenetic regulation of cellular differentiation. Front Genet (2013) 0.89
Histone deacetylase inhibitors and transplantation. Curr Opin Immunol (2007) 0.87
Silencing of the Il2 gene transcription is regulated by epigenetic changes in anergic T cells. Eur J Immunol (2012) 0.87
Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line. Sci Rep (2016) 0.85
Two-step binding of transcription factors causes sequential chromatin structural changes at the activated IL-2 promoter. J Immunol (2011) 0.84
Forkhead transcription factor FOXP3 upregulates CD25 expression through cooperation with RelA/NF-κB. PLoS One (2012) 0.84
Cyclin-dependent kinases: molecular switches controlling anergy and potential therapeutic targets for tolerance. Semin Immunol (2007) 0.83
Genetic and biochemical regulation of CD4 T cell effector differentiation: insights from examination of T cell clonal anergy. Immunol Res (2010) 0.80
Epigenetic patterns associated with the immune dysregulation that accompanies psychosocial distress. Brain Behav Immun (2010) 0.80
T-cell tolerance in cancer. Immunotherapy (2013) 0.79
HIV-1 Infection-Induced Suppression of the Let-7i/IL-2 Axis Contributes to CD4(+) T Cell Death. Sci Rep (2016) 0.79
Activation of silenced cytokine gene promoters by the synergistic effect of TBP-TALE and VP64-TALE activators. PLoS One (2014) 0.78
Thymic regulatory T cell development: role of signalling pathways and transcription factors. Clin Dev Immunol (2013) 0.77
C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection. Open Biol (2016) 0.77
BPTF Is Essential for T Cell Homeostasis and Function. J Immunol (2016) 0.75
Long-Range Transcriptional Control of the Il2 Gene by an Intergenic Enhancer. Mol Cell Biol (2015) 0.75
Guanine nucleotide exchange factor αPIX leads to activation of the Rac 1 GTPase/glycogen phosphorylase pathway in interleukin (IL)-2-stimulated T cells. J Biol Chem (2015) 0.75
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature (2003) 10.76
Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med (2007) 6.61
Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J Exp Med (2005) 3.17
Complex hemodynamics at the apex of an arterial bifurcation induces vascular remodeling resembling cerebral aneurysm initiation. Stroke (2007) 2.58
The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo. J Exp Med (2005) 2.09
Response to Idelalisib in a Patient with Stage IV Merkel-Cell Carcinoma. N Engl J Med (2015) 2.03
Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study. Acta Diabetol (2010) 2.01
Notch signaling augments T cell responsiveness by enhancing CD25 expression. J Immunol (2003) 1.95
Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells. J Immunol (2006) 1.88
Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation. J Biol Chem (2006) 1.84
Alpha interferon potently enhances the anti-human immunodeficiency virus type 1 activity of APOBEC3G in resting primary CD4 T cells. J Virol (2006) 1.84
Ikaros enforces the costimulatory requirement for IL2 gene expression and is required for anergy induction in CD4+ T lymphocytes. J Immunol (2007) 1.61
Impaired T cell function in RANTES-deficient mice. Clin Immunol (2002) 1.60
The regulation of tendon stem cell differentiation by the alignment of nanofibers. Biomaterials (2009) 1.59
BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur J Immunol (2004) 1.44
The photosensitiser xanthurenic acid is not present in normal human lenses. Exp Eye Res (2003) 1.40
Defective activation of protein kinase C and Ras-ERK pathways limits IL-2 production and proliferation by CD4+CD25+ regulatory T cells. J Immunol (2006) 1.37
Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice. J Nutr (2007) 1.35
luxS and arcB control aerobic growth of Actinobacillus actinomycetemcomitans under iron limitation. Infect Immun (2003) 1.32
B7-H3 promotes acute and chronic allograft rejection. Eur J Immunol (2005) 1.31
Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element. Free Radic Biol Med (2008) 1.24
Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration. Cancer Res (2009) 1.19
In vivo assessment of rapid cerebrovascular morphological adaptation following acute blood flow increase. J Neurosurg (2008) 1.19
What is new in management of pediatric ranula? Curr Opin Otolaryngol Head Neck Surg (2014) 1.18
Potent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. J Biol Chem (2002) 1.17
High-fat diet feeding impairs both the expression and activity of AMPKa in rats' skeletal muscle. Biochem Biophys Res Commun (2005) 1.16
Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells. J Immunol (2008) 1.16
Arteriogenesis: noninvasive quantification with multi-detector row CT angiography and three-dimensional volume rendering in rodents. Radiology (2006) 1.16
Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism. J Immunol (2003) 1.15
Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function. Cell Rep (2012) 1.14
MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1. J Cell Mol Med (2010) 1.13
Involvement of chronic stresses in rat islet and INS-1 cell glucotoxicity induced by intermittent high glucose. Mol Cell Endocrinol (2008) 1.13
Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia. Sheng Li Xue Bao (2007) 1.11
Presence of thyrotropin receptor in hepatocytes: not a case of illegitimate transcription. J Cell Mol Med (2009) 1.11
Urinary prostaglandin F2alpha is generated from the isoprostane pathway and not the cyclooxygenase in humans. J Biol Chem (2006) 1.09
Progressive aneurysm development following hemodynamic insult. J Neurosurg (2010) 1.07
Modulation of Kv channel expression and function by TCR and costimulatory signals during peripheral CD4(+) lymphocyte differentiation. J Exp Med (2002) 1.07
Role of extrathyroidal TSHR expression in adipocyte differentiation and its association with obesity. Lipids Health Dis (2012) 1.06
Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages. J Biol Chem (2005) 1.05
Ikaros silences T-bet expression and interferon-gamma production during T helper 2 differentiation. J Biol Chem (2009) 1.05
Opposing roles for the cyclin-dependent kinase inhibitor p27kip1 in the control of CD4+ T cell proliferation and effector function. J Immunol (2005) 1.05
Comparative analysis of E2F family member oncogenic activity. PLoS One (2007) 1.04
Exonic mutations of TSC2/TSC1 are common but not seen in all sporadic pulmonary lymphangioleiomyomatosis. Am J Respir Crit Care Med (2013) 1.04
Cellular and molecular responses of the basilar terminus to hemodynamics during intracranial aneurysm initiation in a rabbit model. J Vasc Res (2011) 1.01
Regiochemistry of neuroprostanes generated from the peroxidation of docosahexaenoic acid in vitro and in vivo. J Biol Chem (2005) 1.01
Organ preservation. Methods Mol Biol (2006) 1.00
Mechanisms of hepatoprotection of Terminalia catappa L. extract on D-Galactosamine-induced liver damage. Am J Chin Med (2004) 1.00
Proteomic analysis of neural differentiation of mouse embryonic stem cells. Proteomics (2005) 1.00
Presentations and management of thyroglossal duct cyst in children versus adults: a review of 106 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2011) 1.00
Proteomics, pathway array and signaling network-based medicine in cancer. Cell Div (2009) 0.99
Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid. J Biol Chem (2002) 0.99
The role of cyclin-dependent kinases in T-cell development, proliferation, and function. Crit Rev Immunol (2006) 0.98
Mechanisms for the formation of isoprostane endoperoxides from arachidonic acid. "Dioxetane" intermediate versus beta-fragmentation of peroxyl radicals. J Biol Chem (2003) 0.98
Foxp3 processing by proprotein convertases and control of regulatory T cell function. J Biol Chem (2008) 0.97
Management of temporomandibular joint ankylosis: 11 years' clinical experience. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.97
Molecular alterations associated with aneurysmal remodeling are localized in the high hemodynamic stress region of a created carotid bifurcation. Neurosurgery (2009) 0.96
Functional SNPs in the SCGB3A2 promoter are associated with susceptibility to Graves' disease. Hum Mol Genet (2009) 0.96
Ghrelin-containing neuron in cerebral cortex and hypothalamus linked with the DVC of brainstem in rat. Regul Pept (2006) 0.95
Foxp3 protein stability is regulated by cyclin-dependent kinase 2. J Biol Chem (2013) 0.95
Comparison of safety and efficacy of insulin glargine and neutral protamine hagedorn insulin in older adults with type 2 diabetes mellitus: results from a pooled analysis. J Am Geriatr Soc (2012) 0.95
De novo DNA methylation is required to restrict T helper lineage plasticity. J Biol Chem (2012) 0.94
Thyroid stimulating hormone, independent of thyroid hormone, can elevate the serum total cholesterol level in patients with coronary heart disease: a cross-sectional design. Nutr Metab (Lond) (2012) 0.94
Captopril inhibits glucose accumulation in retinal cells in diabetes. Invest Ophthalmol Vis Sci (2003) 0.94
The effect of elevated serum soluble CD40 ligand on the prognostic value in patients with acute coronary syndromes. Clin Chim Acta (2004) 0.94
Primary graft failure after heart transplantation. J Transplant (2011) 0.93
MiR-21 modulates chemosensitivity of tongue squamous cell carcinoma cells to cisplatin by targeting PDCD4. Mol Cell Biochem (2014) 0.93
Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: implications for peripheral B and T cell responsiveness. J Immunol (2003) 0.93
Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus. J Biol Chem (2012) 0.93
ELE restrains empty glumes from developing into lemmas. J Genet Genomics (2010) 0.93
FOXP3 inhibits activation-induced NFAT2 expression in T cells thereby limiting effector cytokine expression. J Immunol (2009) 0.93
Mbd2 promotes foxp3 demethylation and T-regulatory-cell function. Mol Cell Biol (2013) 0.92
The cyclopentenone product of lipid peroxidation, 15-A(2t)-isoprostane (8-isoprostaglandin A(2)), is efficiently conjugated with glutathione by human and rat glutathione transferase A4-4. Chem Res Toxicol (2002) 0.92
Ethanol feeding impairs insulin-stimulated glucose uptake in isolated rat skeletal muscle: role of Gs alpha and cAMP. Alcohol Clin Exp Res (2005) 0.91
The cyclin-dependent kinase inhibitor p27kip1 is required for transplantation tolerance induced by costimulatory blockade. J Immunol (2006) 0.91
Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production. J Clin Invest (2015) 0.90
A phase II, open-label study of ramucirumab in combination with paclitaxel and carboplatin as first-line therapy in patients with stage IIIB/IV non-small-cell lung cancer. J Thorac Oncol (2014) 0.90
Identification of the major urinary metabolite of the highly reactive cyclopentenone isoprostane 15-A(2t)-isoprostane in vivo. J Biol Chem (2005) 0.90
Circulating microRNA-21 (MIR-21) and phosphatase and tensin homolog (PTEN) are promising novel biomarkers for detection of oral squamous cell carcinoma. Biomarkers (2014) 0.90
Various presentations of fourth branchial pouch sinus tract during surgery. Acta Otolaryngol (2012) 0.89
Mechanism of T cell-mediated endothelial apoptosis. Transplantation (2002) 0.89
In vivo and in vitro lipid peroxidation of arachidonate esters: the effect of fish oil omega-3 lipids on product distribution. J Am Chem Soc (2006) 0.89
NOX4-Dependent Hydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 Atrial Cells: Relationship to Hypertension. Front Physiol (2012) 0.89
Decreased mobilization of endothelial progenitor cells contributes to impaired neovascularization in diabetes. Clin Exp Pharmacol Physiol (2009) 0.89
Protein signatures for classification and prognosis of gastric cancer a signaling pathway-based approach. Am J Pathol (2011) 0.89
Aberrant c-erbB2 expression in cell clusters overlying focally disrupted breast myoepithelial cell layers: a trigger or sign for emergence of more aggressive cell clones? Int J Biol Sci (2008) 0.88
CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice. Eur J Immunol (2009) 0.88
Identification of novel autoxidation products of the omega-3 fatty acid eicosapentaenoic acid in vitro and in vivo. J Biol Chem (2007) 0.88
Hydrogen sulfide protects against high-glucose-induced apoptosis in endothelial cells. J Cardiovasc Pharmacol (2012) 0.87
Histone deacetylase inhibitors and transplantation. Curr Opin Immunol (2007) 0.87
Identification of small Sca-1(+), Lin(-), CD45(-) multipotential cells in the neonatal murine retina. Exp Hematol (2009) 0.87
Cyclin-dependent kinase 2 controls peripheral immune tolerance. J Immunol (2012) 0.86
Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate. Endocrinology (2007) 0.86
The regulation and function of the NUAK family. J Mol Endocrinol (2013) 0.86
Chronically elevated glucose-induced apoptosis is mediated by inactivation of Akt in cultured Müller cells. Biochem Biophys Res Commun (2005) 0.86
Intervention with cilostazol attenuates renal inflammation in streptozotocin-induced diabetic rats. Life Sci (2008) 0.86
Peripheral effects of nesfatin-1 on glucose homeostasis. PLoS One (2013) 0.86
Upregulated expression of miR-106a by DNA hypomethylation plays an oncogenic role in hepatocellular carcinoma. Tumour Biol (2014) 0.85
Berbamine protects the heart from ischemia/reperfusion injury by maintaining cytosolic Ca(2+) homeostasis and preventing calpain activation. Circ J (2012) 0.85
Curative effect of acupuncture and moxibustion on insomnia: a randomized clinical trial. J Tradit Chin Med (2013) 0.85