Published in Clin Gastroenterol Hepatol on April 01, 2005
Genome-wide association studies and genetic risk assessment of liver diseases. Nat Rev Gastroenterol Hepatol (2010) 0.99
Alpha-1 antitrypsin deficiency: a conformational disease associated with lung and liver manifestations. J Inherit Metab Dis (2008) 0.95
Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency. Clin Gastroenterol Hepatol (2011) 0.94
Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice. J Clin Invest (2013) 0.94
Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis. Drug Des Devel Ther (2011) 0.92
Alpha-1-antitrypsin in pathogenesis of hepatocellular carcinoma. Hepat Mon (2012) 0.86
Alpha-1-antitrypsin phenotypes in adult liver disease patients. Ups J Med Sci (2009) 0.83
Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency. Biologics (2009) 0.82
Liver test results do not identify liver disease in adults with α(1)-antitrypsin deficiency. Clin Gastroenterol Hepatol (2012) 0.81
Is PiSS Alpha-1 Antitrypsin Deficiency Associated with Disease? Pulm Med (2010) 0.78
Alcohol use predicts ER visits in individuals with alpha-1 antitrypsin deficiency (AATD) associated COPD. COPD (2012) 0.77
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Bleeding from oesophageal varices in pregnancy. BMJ Case Rep (2013) 0.75
Genotyping diagnosis of alpha-1 antitrypsin deficiency in Saudi adults with liver cirrhosis. Medicine (Baltimore) (2017) 0.75
Α₁-antitrypsin PiMZ heterozygosity has an independent aggravating effect on liver fibrosis in alcoholic liver disease. Virchows Arch (2014) 0.75
[Hereditary hemochromatosis, alpha-1-antitrypsin deficiency and Wilson's disease. Pathogenesis, clinical findings and pathways to diagnosis]. Pathologe (2008) 0.75
Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med (2006) 9.17
Efficacy and safety of sirolimus in lymphangioleiomyomatosis. N Engl J Med (2011) 6.74
A randomized study of endobronchial valves for advanced emphysema. N Engl J Med (2010) 6.23
An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med (2012) 5.37
Measuring blood pressure for decision making and quality reporting: where and how many measures? Ann Intern Med (2011) 5.31
Long-term effects of inhaled corticosteroids on FEV1 in patients with chronic obstructive pulmonary disease. A meta-analysis. Ann Intern Med (2003) 2.94
Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease. Am J Respir Crit Care Med (2007) 2.86
Medical comorbidity in women and men with schizophrenia: a population-based controlled study. J Gen Intern Med (2006) 2.79
Antimicrobial resistance trends and outbreak frequency in United States hospitals. Clin Infect Dis (2003) 2.54
Prediction of esophageal varices in patients with cirrhosis. J Clin Gastroenterol (2002) 2.45
Evaluation of an intensive insulin protocol for septic patients in a medical intensive care unit. Crit Care Med (2006) 2.22
Involvement of novel autophosphorylation sites in ATM activation. EMBO J (2006) 1.94
Delivery of antioxidative enzyme genes protects against ischemia/reperfusion-induced liver injury in mice. Liver Transpl (2006) 1.90
Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1. Gastroenterology (2009) 1.89
Analysis of local tissue-specific gene expression in cellular micropatterns. Anal Chem (2006) 1.81
Biologic lung volume reduction in advanced upper lobe emphysema: phase 2 results. Am J Respir Crit Care Med (2009) 1.78
Limitations to the 6-minute walk test in interstitial lung disease and pulmonary hypertension in scleroderma. J Rheumatol (2009) 1.78
Preoperative statin treatment is associated with reduced postoperative mortality and morbidity in patients undergoing cardiac surgery: an 8-year retrospective cohort study. J Thorac Cardiovasc Surg (2006) 1.78
ATM signaling and genomic stability in response to DNA damage. Mutat Res (2005) 1.75
Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential. Gastroenterology (2003) 1.74
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology (2006) 1.71
Serum VEGF-D a concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial. Lancet Respir Med (2013) 1.69
Oxidative stress and regulation of anti-oxidant enzymes in cytochrome P4502E1 transgenic mouse model of non-alcoholic fatty liver. J Gastroenterol Hepatol (2010) 1.68
Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation. Am J Physiol Gastrointest Liver Physiol (2009) 1.63
Effect of a high-fiber diet vs a fiber-supplemented diet on C-reactive protein level. Arch Intern Med (2007) 1.62
Aprataxin, a novel protein that protects against genotoxic stress. Hum Mol Genet (2004) 1.60
alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note. Chest (2008) 1.60
Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage. J Cell Biol (2007) 1.59
SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity. Nucleic Acids Res (2003) 1.59
Gulf War veterans with anxiety: prevalence, comorbidity, and risk factors. Epidemiology (2004) 1.57
Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells. Proc Natl Acad Sci U S A (2003) 1.55
Treatment of pulmonary arterial hypertension: a preliminary decision analysis. Chest (2003) 1.54
Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo. Stem Cells (2007) 1.54
Percutaneous injury, blood exposure, and adherence to standard precautions: are hospital-based health care providers still at risk? Clin Infect Dis (2003) 1.53
Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. Stem Cells (2010) 1.52
Neurocognitive impairment in obstructive sleep apnea. Chest (2012) 1.50
Adjusting O'Brien's test to control type I error for the generalized nonparametric Behrens-Fisher problem. Biometrics (2005) 1.47
Targeting hepatocytes for drug and gene delivery: emerging novel approaches and applications. Front Biosci (2002) 1.46
COPD and lung cancer: are they both airways diseases? Chest (2010) 1.41
Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM. J Biol Chem (2002) 1.41
Dietary magnesium and C-reactive protein levels. J Am Coll Nutr (2005) 1.40
Obese man treated with drotrecogin alfa (activated). Ann Pharmacother (2003) 1.38
Impact of oral cyclophosphamide on health-related quality of life in patients with active scleroderma lung disease: results from the scleroderma lung study. Arthritis Rheum (2007) 1.35
Posttraumatic stress disorder and self-reported physical health status among U.S. Military personnel serving during the Gulf War period: a population-based study. Psychosomatics (2002) 1.33
Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. J Hepatol (2011) 1.30
Serum apoptosis markers in acute liver failure: a pilot study. Clin Gastroenterol Hepatol (2007) 1.29
Prevalence of hypertension by duration and age at exposure to the stroke belt. J Am Soc Hypertens (2010) 1.29
Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiency. Ann Behav Med (2007) 1.27
Physician knowledge, attitudes and practices regarding a widely implemented guideline. J Eval Clin Pract (2002) 1.26
Pneumothorax in cystic fibrosis. Chest (2005) 1.25
Age and race impact the association between BMI and CVD mortality in women. Public Health Rep (2007) 1.24
A comparison of missing data methods for hypothesis tests of the treatment effect in substance abuse clinical trials: a Monte-Carlo simulation study. Subst Abuse Treat Prev Policy (2008) 1.23
Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer. Proc Natl Acad Sci U S A (2002) 1.23
Benchmarking Veterans Affairs Medical Centers in the delivery of preventive health services: comparison of methods. Med Care (2002) 1.23
Delay in diagnosis of alpha1-antitrypsin deficiency: a continuing problem. Chest (2005) 1.22
Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma. Exp Mol Pathol (2010) 1.22
Application of beta regression to analyze ischemic stroke volume in NINDS rt-PA clinical trials. Neuroepidemiology (2011) 1.21
Differentiation of human and mouse embryonic stem cells along a hepatocyte lineage. Cell Transplant (2004) 1.15
Statistical design considerations for pilot studies transitioning therapies from the bench to the bedside. J Transl Med (2004) 1.15
Nephrogenic systemic fibrosis after exposure to gadolinium in patients with renal failure. Nephrol Dial Transplant (2007) 1.14
Modafinil and cocaine interactions. Am J Drug Alcohol Abuse (2006) 1.14
Organizational predictors of adherence to ambulatory care screening guidelines. Med Care (2002) 1.13
Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension. Alcohol Alcohol (2009) 1.13
Mechanism of regulation of bcl-2 mRNA by nucleolin and A+U-rich element-binding factor 1 (AUF1). J Biol Chem (2010) 1.12
Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency. Thorax (2007) 1.12
Pulmonary manifestations of systemic lupus erythematosus. Clin Chest Med (2010) 1.09
The impact of loss to follow-up on hypothesis tests of the treatment effect for several statistical methods in substance abuse clinical trials. J Subst Abuse Treat (2008) 1.09
Randomization in substance abuse clinical trials. Subst Abuse Treat Prev Policy (2006) 1.09
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. Am J Respir Cell Mol Biol (2007) 1.08
A rank-based sample size method for multiple outcomes in clinical trials. Stat Med (2008) 1.07
Autophosphorylation and ATM activation: additional sites add to the complexity. J Biol Chem (2010) 1.07
Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. Stem Cells Transl Med (2013) 1.06
Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate. J Hepatol (2002) 1.05
Role of MAPK phosphatase-1 in sustained activation of JNK during ethanol-induced apoptosis in hepatocyte-like VL-17A cells. J Biol Chem (2007) 1.04
Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice. Hepatology (2004) 1.01
Organizational and provider characteristics fostering smoking cessation practice guideline adherence: an empirical look. J Ambul Care Manage (2002) 1.00
Validation of blood phosphatidylethanol as an alcohol consumption biomarker in patients with chronic liver disease. Alcohol Clin Exp Res (2014) 0.98
Using global statistical tests in long-term Parkinson's disease clinical trials. Mov Disord (2009) 0.98
Differences in cardiovascular disease mortality associated with body mass between Black and White persons. Am J Public Health (2007) 0.98
ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control. J Biol Chem (2011) 0.98
New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes. Stem Cell Rev (2011) 0.97
Effectiveness of a nationally implemented smoking cessation guideline on provider and patient practices. Prev Med (2003) 0.97
Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Ann Intern Med (2016) 0.97
Cultivating liver cells on printed arrays of hepatocyte growth factor. Biomaterials (2009) 0.96
Cultivating hepatocytes on printed arrays of HGF and BMP7 to characterize protective effects of these growth factors during in vitro alcohol injury. Biomaterials (2010) 0.96
Mapping the Location of Prognostically Significant Microcirculatory Patterns in Ciliary Body and Choroidal Melanomas. Pathol Oncol Res (1996) 0.95
Emphysema lung lobe volume reduction: effects on the ipsilateral and contralateral lobes. Eur Radiol (2012) 0.94
Multifunctional protein microarrays for cultivation of cells and immunodetection of secreted cellular products. Anal Chem (2008) 0.94
Sensitivity and specificity of urinary ethyl glucuronide and ethyl sulfate in liver disease patients. Alcohol Clin Exp Res (2012) 0.93
Prospective evaluation of a 3.1-mm battery-powered esophagoscope in screening for esophageal varices in cirrhotic patients. Am J Gastroenterol (2003) 0.93
Decellularized liver matrix as a carrier for the transplantation of human fetal and primary hepatocytes in mice. Liver Transpl (2011) 0.92
Relationship between depression and pancreatic cancer in the general population. Psychosom Med (2003) 0.92
Health-related quality of life in Gulf War era military personnel. Am J Epidemiol (2002) 0.91
Slope Estimation for Bivariate Longitudinal Outcomes Adjusting for Informative Right Censoring Using Discrete Survival Model: Application to the Renal Transplant Cohort. J R Stat Soc Ser A Stat Soc (2011) 0.91
The biopsy GAVE the diagnosis. Clin Gastroenterol Hepatol (2011) 0.91
Move over LOCF: principled methods for handling missing data in sleep disorder trials. Sleep Med (2011) 0.91