Published in J Biol Chem on June 22, 2010
RNA-binding protein nucleolin in disease. RNA Biol (2012) 1.47
RNA binding protein/RNA element interactions and the control of translation. Curr Protein Pept Sci (2012) 1.24
Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs. Nucleic Acids Res (2011) 1.21
Post-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulation. Biochim Biophys Acta (2012) 1.16
In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation. J Exp Med (2013) 1.13
Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1. Front Biosci (Landmark Ed) (2011) 1.06
Cell-specific aptamers as emerging therapeutics. J Nucleic Acids (2011) 1.04
Coordinate regulation of mRNA decay networks by GU-rich elements and CELF1. Curr Opin Genet Dev (2011) 0.99
Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk. J Biol Chem (2012) 0.94
G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol. Leuk Res (2013) 0.92
Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells. PLoS One (2012) 0.92
Nucleolin mediates microRNA-directed CSF-1 mRNA deadenylation but increases translation of CSF-1 mRNA. Mol Cell Proteomics (2013) 0.88
Heat shock protein 90 stabilizes nucleolin to increase mRNA stability in mitosis. J Biol Chem (2011) 0.86
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer. Nucleic Acids Res (2015) 0.84
Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ. Oncogene (2014) 0.83
MiR-200c regulates Noxa expression and sensitivity to proteasomal inhibitors. PLoS One (2012) 0.83
Post-transcriptional regulation of BCL2 mRNA by the RNA-binding protein ZFP36L1 in malignant B cells. PLoS One (2014) 0.82
Pleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolin. Vasc Cell (2012) 0.81
A ribonucleoprotein complex protects the interleukin-6 mRNA from degradation by distinct herpesviral endonucleases. PLoS Pathog (2015) 0.81
Hepatoma-derived growth factor and nucleolin exist in the same ribonucleoprotein complex. BMC Biochem (2013) 0.80
Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size. Cell Rep (2016) 0.79
Hallmarks of cancer and AU-rich elements. Wiley Interdiscip Rev RNA (2016) 0.78
Human anti-nucleolin recombinant immunoagent for cancer therapy. Proc Natl Acad Sci U S A (2015) 0.77
Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1. Biomolecules (2015) 0.77
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1. Sci Rep (2016) 0.76
Regulation of CCN1 via the 3'-untranslated region. J Cell Commun Signal (2013) 0.76
Induced expression of nucleolin phosphorylation-deficient mutant confers dominant-negative effect on cell proliferation. PLoS One (2014) 0.75
Deletion of AU-rich elements within the Bcl2 3'UTR reduces protein expression and B cell survival in vivo. PLoS One (2015) 0.75
Novel Gefitinib Formulation with Improved Oral Bioavailability in Treatment of A431 Skin Carcinoma. Pharm Res (2015) 0.75
Roles of nucleolin. Focus on cancer and anti-cancer therapy. Saudi Med J (2016) 0.75
AS1411-Induced Growth Inhibition of Glioma Cells by Up-Regulation of p53 and Down-Regulation of Bcl-2 and Akt1 via Nucleolin. PLoS One (2016) 0.75
Nucleolin down-regulation is involved in ADP-induced cell cycle arrest in S phase and cell apoptosis in vascular endothelial cells. PLoS One (2014) 0.75
Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell (2001) 7.79
AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res (2006) 6.22
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol (1999) 5.55
Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol Cell Biol (1993) 5.24
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO J (2000) 4.41
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. EMBO J (2002) 4.13
Ribonomics: identifying mRNA subsets in mRNP complexes using antibodies to RNA-binding proteins and genomic arrays. Methods (2002) 3.92
Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay. EMBO J (1997) 3.91
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol Cell (2004) 3.71
Messenger RNA turnover in eukaryotes: pathways and enzymes. Crit Rev Biochem Mol Biol (2004) 3.67
Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA. J Biol Chem (1999) 3.43
A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements. EMBO J (2001) 2.63
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation. Genes Dev (2000) 2.54
The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res (2008) 2.39
Structure and genomic organization of the human AUF1 gene: alternative pre-mRNA splicing generates four protein isoforms. Genomics (1998) 2.17
Nucleolin: a multiFACeTed protein. Trends Cell Biol (2006) 2.15
The glycine-rich domain of nucleolin has an unusual supersecondary structure responsible for its RNA-helix-destabilizing properties. J Biol Chem (1992) 2.07
Antiproliferative activity of G-rich oligonucleotides correlates with protein binding. J Biol Chem (1999) 2.05
Discovery and development of anticancer aptamers. Mol Cancer Ther (2006) 2.01
Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover. Mol Cell Biol (2001) 1.92
Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin. EMBO J (2000) 1.91
The cell-surface-expressed nucleolin is associated with the actin cytoskeleton. Exp Cell Res (2000) 1.80
Nucleolin interacts with several ribosomal proteins through its RGG domain. J Biol Chem (1998) 1.77
Nucleolin is a sequence-specific RNA-binding protein: characterization of targets on pre-ribosomal RNA. J Mol Biol (1996) 1.76
High affinity interactions of nucleolin with G-G-paired rDNA. J Biol Chem (1999) 1.73
Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3'-untranslated region of amyloid protein precursor mRNA. J Biol Chem (1995) 1.72
Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA. Blood (2007) 1.62
Identification of nucleolin as an AU-rich element binding protein involved in bcl-2 mRNA stabilization. J Biol Chem (2003) 1.58
AGRO100 inhibits activation of nuclear factor-kappaB (NF-kappaB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin. Mol Cancer Ther (2006) 1.44
Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay. Mol Cell Biol (2006) 1.44
Increased stability of nucleolin in proliferating cells by inhibition of its self-cleaving activity. J Biol Chem (1991) 1.44
Identification of nucleolin and nucleophosmin as genotoxic stress-responsive RNA-binding proteins. Nucleic Acids Res (2002) 1.37
Two RNA-binding domains determine the RNA-binding specificity of nucleolin. J Biol Chem (1997) 1.37
An in vitro system using HeLa cytoplasmic extracts that reproduces regulated mRNA stability. Methods (1999) 1.36
Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells. Mol Pharmacol (2009) 1.36
AUF1 Is a bcl-2 A + U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis. J Biol Chem (2002) 1.36
Nucleolin links to arsenic-induced stabilization of GADD45alpha mRNA. Nucleic Acids Res (2006) 1.23
A nucleolin-binding 3' untranslated region element stabilizes beta-globin mRNA in vivo. Mol Cell Biol (2006) 1.23
Localization of nucleolin binding sites on human and mouse pre-ribosomal RNA. Biochimie (1996) 1.21
Identification of Ebp1 as a component of cytoplasmic bcl-2 mRNP (messenger ribonucleoprotein particle) complexes. Biochem J (2006) 1.21
Interaction of nucleolin with an evolutionarily conserved pre-ribosomal RNA sequence is required for the assembly of the primary processing complex. J Biol Chem (2000) 1.16
A conserved AU-rich element in the 3' untranslated region of bcl-2 mRNA is endowed with a destabilizing function that is involved in bcl-2 down-regulation during apoptosis. FASEB J (2000) 1.12
Nucleolin is a second component of the CD154 mRNA stability complex that regulates mRNA turnover in activated T cells. J Immunol (2004) 1.11
Role of nucleolin in posttranscriptional control of MMP-9 expression. Biochim Biophys Acta (2005) 1.08
FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1. RNA (2007) 1.08
Regulation of Bcl-2 expression by HuR in HL60 leukemia cells and A431 carcinoma cells. Mol Cancer Res (2009) 1.07
Two different combinations of RNA-binding domains determine the RNA binding specificity of nucleolin. J Biol Chem (2001) 1.05
Nucleolin stabilizes Bcl-X L messenger RNA in response to UVA irradiation. Cancer Res (2008) 1.05
Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover. Mol Biol Cell (2007) 0.97
CA repeats in the 3'-untranslated region of bcl-2 mRNA mediate constitutive decay of bcl-2 mRNA. J Biol Chem (2004) 0.96
mRNA stability control: a clandestine force in normal and malignant hematopoiesis. Leukemia (2007) 0.94
Taxol- and okadaic acid-induced destabilization of bcl-2 mRNA is associated with decreased binding of proteins to a bcl-2 instability element. Biochem Pharmacol (2003) 0.89
Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin. Nucleic Acids Res (2003) 0.84
The preparation and applications of cytoplasmic extracts from mammalian cells for studying aspects of mRNA decay. Methods Enzymol (2008) 0.82
B cell lymphoma (Bcl)-2 protein is the major determinant in bcl-2 adenine-uridine-rich element turnover overcoming HuR activity. J Biol Chem (2009) 0.82
Prediction of esophageal varices in patients with cirrhosis. J Clin Gastroenterol (2002) 2.45
The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res (2008) 2.39
Follow-up of patients with curatively resected colorectal cancer: a practice guideline. BMC Cancer (2003) 2.26
Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review. Radiother Oncol (2002) 2.25
Adjuvant therapy for stage II colon cancer: a systematic review from the Cancer Care Ontario Program in evidence-based care's gastrointestinal cancer disease site group. J Clin Oncol (2004) 1.86
Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA. Blood (2007) 1.62
Identification of nucleolin as an AU-rich element binding protein involved in bcl-2 mRNA stabilization. J Biol Chem (2003) 1.58
Neoadjuvant or adjuvant therapy for resectable gastric cancer? A practice guideline. Can J Surg (2002) 1.47
Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells. Mol Pharmacol (2009) 1.36
Neoadjuvant or adjuvant therapy for resectable esophageal cancer: a systematic review and meta-analysis. BMC Med (2004) 1.33
Serum apoptosis markers in acute liver failure: a pilot study. Clin Gastroenterol Hepatol (2007) 1.29
Identification of Ebp1 as a component of cytoplasmic bcl-2 mRNP (messenger ribonucleoprotein particle) complexes. Biochem J (2006) 1.21
Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension. Alcohol Alcohol (2009) 1.13
Wear debris inhibition of anti-osteoclastogenic signaling by interleukin-6 and interferon-gamma. Mechanistic insights and implications for periprosthetic osteolysis. J Bone Joint Surg Am (2006) 1.09
Regulation of Bcl-2 expression by HuR in HL60 leukemia cells and A431 carcinoma cells. Mol Cancer Res (2009) 1.07
Retinoid-induced apoptosis in HL-60 cells is associated with nucleolin down-regulation and destabilization of Bcl-2 mRNA. Mol Pharmacol (2004) 1.05
Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate. J Hepatol (2002) 1.05
Factors associated with advanced liver disease in adults with alpha1-antitrypsin deficiency. Clin Gastroenterol Hepatol (2005) 1.04
Direct binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradation. J Mol Biol (2009) 1.01
Validation of blood phosphatidylethanol as an alcohol consumption biomarker in patients with chronic liver disease. Alcohol Clin Exp Res (2014) 0.98
Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Ann Intern Med (2016) 0.97
Neoadjuvant or adjuvant therapy for resectable esophageal cancer: a clinical practice guideline. BMC Cancer (2004) 0.96
Singlet oxygen mediated DNA degradation by copper nanoparticles: potential towards cytotoxic effect on cancer cells. J Nanobiotechnology (2011) 0.94
Prospective evaluation of a 3.1-mm battery-powered esophagoscope in screening for esophageal varices in cirrhotic patients. Am J Gastroenterol (2003) 0.93
Sensitivity and specificity of urinary ethyl glucuronide and ethyl sulfate in liver disease patients. Alcohol Clin Exp Res (2012) 0.93
The use of preoperative radiotherapy in the management of patients with clinically resectable rectal cancer: a practice guideline. BMC Med (2003) 0.91
The biopsy GAVE the diagnosis. Clin Gastroenterol Hepatol (2011) 0.91
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling. BMC Bioinformatics (2010) 0.90
Combined modality radiotherapy and chemotherapy in nonsurgical management of localized carcinoma of the esophagus: a practice guideline. Int J Radiat Oncol Biol Phys (2003) 0.90
Taxol- and okadaic acid-induced destabilization of bcl-2 mRNA is associated with decreased binding of proteins to a bcl-2 instability element. Biochem Pharmacol (2003) 0.89
Two-year outcomes in initial survivors with acute liver failure: results from a prospective, multicentre study. Liver Int (2014) 0.89
Posttransplantation lymphoproliferative disorder--the great mimic in liver transplantation: appraisal of the clinicopathologic spectrum and the role of Epstein-Barr virus. Liver Transpl (2007) 0.88
Probing multifractality in tissue refractive index: prospects for precancer detection. Opt Lett (2013) 0.88
Adjuvant chemotherapy for adults with malignant glioma: a systematic review. Can J Neurol Sci (2007) 0.88
The treatment of locally advanced pancreatic cancer: a practice guideline. Can J Gastroenterol (2003) 0.85
Collagen binding alpha2beta1 and alpha1beta1 integrins play contrasting roles in regulation of Ets-1 expression in human liver myofibroblasts. Mol Cell Biochem (2006) 0.83
Autonomic dysfunction and gastroparesis in cirrhosis. J Clin Gastroenterol (2004) 0.83
Quantitation of gene-specific DNA damage by competitive PCR. Anal Biochem (2002) 0.83
PMA induces stabilization of oncostatin M mRNA in human lymphoma U937 cells. Biochem J (2008) 0.82
Expression of oncostatin M and its receptors in normal and cirrhotic human liver. J Hepatol (2005) 0.82
Needles in haystacks. Am J Gastroenterol (2007) 0.82
Pulmonary hypertension after liver transplantation: case presentation and review of the literature. Liver Transpl (2009) 0.82
Alcohol and the liver. Curr Opin Gastroenterol (2005) 0.81
Hair ethyl glucuronide is highly sensitive and specific for detecting moderate-to-heavy drinking in patients with liver disease. Alcohol Alcohol (2012) 0.81
Elevated levels of endothelin-1 in hepatic venous blood are associated with intrapulmonary vasodilatation in humans. Dig Dis Sci (2011) 0.80
Usefulness of international normalized ratio to predict bleeding complications in patients with end-stage liver disease who undergo cardiac catheterization. Am J Cardiol (2012) 0.80
Complex haplotype structure of the human GNAS gene identifies a recombination hotspot centred on a single nucleotide polymorphism widely used in association studies. Pharmacogenetics (2004) 0.80
LDL immune complexes stimulate LDL receptor expression in U937 histiocytes via extracellular signal-regulated kinase and AP-1. J Lipid Res (2003) 0.80
Chronic pain among liver transplant candidates. Prog Transplant (2012) 0.79
Sliding resistance of polycarbonate self-ligating brackets and stainless steel esthetic archwires. Prog Orthod (2012) 0.79
Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane. J Biol Chem (2010) 0.78
Overexpression of nucleolin in engrafted acute myelogenous leukemia cells. Am J Hematol (2009) 0.78
Comparative studies of oncostatin M expression in the tissues of adult rodents. Anat Rec A Discov Mol Cell Evol Biol (2005) 0.78
Oncostatin M stimulates tissue inhibitor of metalloproteinase-1 via a MEK-sensitive mechanism in human myofibroblasts. J Hepatol (2002) 0.78
Rituximab-responsive cryoglobulinemic glomerulonephritis in a patient with autoimmune hepatitis. J Clin Gastroenterol (2008) 0.78
Drug-induced destabilization of bcl-2 mRNA: a new approach for inducing apoptosis in tumor cells. Curr Opin Investig Drugs (2004) 0.78
The 3'-untranslated region length and AU-rich RNA location modulate RNA-protein interaction and translational control of β2-adrenergic receptor mRNA. Mol Cell Biochem (2011) 0.78
Hepatocellular adenoma in men: a rare cause for liver resection. Am Surg (2011) 0.77
Probing the fractal pattern and organization of Bacillus thuringiensis bacteria colonies growing under different conditions using quantitative spectral light scattering polarimetry. J Biomed Opt (2013) 0.77
Glucose induced fractal colony pattern of Bacillus thuringiensis. J Theor Biol (2010) 0.77
Cigarette smoke extract induced protein phosphorylation changes in human microvascular endothelial cells in vitro. Anal Bioanal Chem (2009) 0.77
Role of plasma membrane disruption in reference moist smokeless tobacco-induced cell death. Toxicol Lett (2010) 0.76
A genetic network that balances two outcomes utilizes asymmetric recognition of operator sites. Biophys J (2012) 0.75
Child-Turcotte-Pugh Class is Best at Stratifying Risk in Variceal Hemorrhage: Analysis of a US Multicenter Prospective Study. J Clin Gastroenterol (2016) 0.75
Hepatocellular carcinoma: its past, present, and future. Clin Liver Dis (2011) 0.75
Uprighting an impacted second molar with a spring anchored to a composite support. J Clin Orthod (2008) 0.75
Correction of a malocclusion caused by a dentigerous cyst. J Clin Orthod (2005) 0.75
Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the nuclear matrix. Mol Pharmacol (2006) 0.75
Laparoscopic hepatic resection: the MUSC experience. J S C Med Assoc (2008) 0.75
Potential importance of glomerular citrate synthase activity in remnant nephropathy. Kidney Int (2003) 0.75
Copper(II) complex of methionine conjugated bis-pyrazole based ligand promotes dual pathway for DNA cleavage. Dalton Trans (2013) 0.75
Regulatory mechanism of G protein-coupled receptor trafficking to the plasma membrane: a role for mRNA localization. Methods Enzymol (2013) 0.75