PubRank

Daniel Kahne

Author PubWeight™ 120.75‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli. Cell 2005 8.22
2 The bacterial cell envelope. Cold Spring Harb Perspect Biol 2010 5.14
3 Structure and function of an essential component of the outer membrane protein assembly machine. Science 2007 3.85
4 Reconstitution of outer membrane protein assembly from purified components. Science 2010 3.30
5 Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev 2007 3.24
6 Advances in understanding bacterial outer-membrane biogenesis. Nat Rev Microbiol 2006 3.23
7 Chemical conditionality: a genetic strategy to probe organelle assembly. Cell 2005 3.12
8 Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc Natl Acad Sci U S A 2007 3.09
9 Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A 2006 2.87
10 YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol Microbiol 2006 2.84
11 β-Barrel membrane protein assembly by the Bam complex. Annu Rev Biochem 2011 2.55
12 Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A 2008 2.21
13 Transport of lipopolysaccharide across the cell envelope: the long road of discovery. Nat Rev Microbiol 2009 2.07
14 Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate. Proc Natl Acad Sci U S A 2003 1.96
15 Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli. Proc Natl Acad Sci U S A 2012 1.91
16 Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chem Biol 2002 1.90
17 Probing the barrier function of the outer membrane with chemical conditionality. ACS Chem Biol 2006 1.86
18 Characterization of the two-protein complex in Escherichia coli responsible for lipopolysaccharide assembly at the outer membrane. Proc Natl Acad Sci U S A 2010 1.85
19 Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis. Proc Natl Acad Sci U S A 2007 1.68
20 The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel. Proc Natl Acad Sci U S A 2011 1.68
21 Proteins required for lipopolysaccharide assembly in Escherichia coli form a transenvelope complex. Biochemistry 2010 1.54
22 Nonconsecutive disulfide bond formation in an essential integral outer membrane protein. Proc Natl Acad Sci U S A 2010 1.48
23 Lipoprotein LptE is required for the assembly of LptD by the beta-barrel assembly machine in the outer membrane of Escherichia coli. Proc Natl Acad Sci U S A 2011 1.41
24 Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. J Bacteriol 2005 1.41
25 Distinct single-cell morphological dynamics under beta-lactam antibiotics. Mol Cell 2012 1.39
26 Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli. Science 2012 1.37
27 Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. J Am Chem Soc 2011 1.37
28 Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. J Biol Chem 2007 1.36
29 Regulated assembly of the transenvelope protein complex required for lipopolysaccharide export. Biochemistry 2012 1.35
30 Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery. Proc Natl Acad Sci U S A 2009 1.29
31 Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. J Am Chem Soc 2005 1.23
32 Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design. ACS Chem Biol 2008 1.19
33 Complete characterization of the seventeen step moenomycin biosynthetic pathway. Biochemistry 2009 1.19
34 Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II. J Am Chem Soc 2013 1.18
35 AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A. Chem Biol 2005 1.18
36 The reconstituted Escherichia coli Bam complex catalyzes multiple rounds of β-barrel assembly. Biochemistry 2011 1.17
37 D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. J Bacteriol 2013 1.15
38 The structural basis for induction of VanB resistance. J Am Chem Soc 2002 1.15
39 In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. J Am Chem Soc 2005 1.13
40 Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate. Proc Natl Acad Sci U S A 2012 1.12
41 Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export. Science 2012 1.11
42 The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. J Am Chem Soc 2010 1.11
43 Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. J Am Chem Soc 2013 1.10
44 Isolated peptidoglycan glycosyltransferases from different organisms produce different glycan chain lengths. J Am Chem Soc 2008 1.09
45 The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains. J Bacteriol 2013 1.08
46 A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases. J Am Chem Soc 2005 1.05
47 Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn. Cancer Immunol Immunother 2004 1.05
48 On the essentiality of lipopolysaccharide to Gram-negative bacteria. Curr Opin Microbiol 2013 1.04
49 Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. J Am Chem Soc 2011 1.04
50 Use of a retroinverso p53 peptide as an inhibitor of MDM2. J Am Chem Soc 2004 1.03
51 Stochastic detection of monovalent and bivalent protein-ligand interactions. Angew Chem Int Ed Engl 2004 1.02
52 Characterization of NovP and NovN: completion of novobiocin biosynthesis by sequential tailoring of the noviosyl ring. Angew Chem Int Ed Engl 2004 1.00
53 Reconstitution of peptidoglycan cross-linking leads to improved fluorescent probes of cell wall synthesis. J Am Chem Soc 2014 1.00
54 Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Proc Natl Acad Sci U S A 2014 0.98
55 Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction. J Am Chem Soc 2014 0.97
56 Crystallographic analysis of an 8-mer p53 peptide analogue complexed with MDM2. J Am Chem Soc 2006 0.96
57 A unifying nitrososynthase involved in nitrosugar biosynthesis. J Am Chem Soc 2008 0.96
58 bam Lipoproteins Assemble BamA in vitro. Biochemistry 2013 0.95
59 Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry. J Am Chem Soc 2011 0.94
60 Detection of bacterial toxins with monosaccharide arrays. Biosens Bioelectron 2005 0.93
61 A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis. J Am Chem Soc 2010 0.93
62 Initial characterization of novobiocic acid noviosyl transferase activity of NovM in biosynthesis of the antibiotic novobiocin. Biochemistry 2003 0.90
63 Reconstitution and characterization of a new desosaminyl transferase, EryCIII, from the erythromycin biosynthetic pathway. J Am Chem Soc 2004 0.90
64 AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A. Biochemistry 2004 0.90
65 Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin. Proc Natl Acad Sci U S A 2004 0.90
66 Validation of inhibitors of an ABC transporter required to transport lipopolysaccharide to the cell surface in Escherichia coli. Bioorg Med Chem 2013 0.88
67 Development of an activity assay for discovery of inhibitors of lipopolysaccharide transport. J Am Chem Soc 2010 0.88
68 N-methylimidazolium chloride-catalyzed pyrophosphate formation: application to the synthesis of Lipid I and NDP-sugar donors. Bioorg Med Chem Lett 2011 0.87
69 Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway. Biochemistry 2005 0.86
70 A practical method for the stereoselective generation of beta-2-deoxy glycosyl phosphates. Org Lett 2004 0.86
71 Modular synthesis of diphospholipid oligosaccharide fragments of the bacterial cell wall and their use to study the mechanism of moenomycin and other antibiotics. Tetrahedron 2011 0.86
72 Tailoring of glycopeptide scaffolds by the acyltransferases from the teicoplanin and A-40,926 biosynthetic operons. Chem Biol 2005 0.85
73 Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors. J Am Chem Soc 2013 0.85
74 Moenomycin resistance mutations in Staphylococcus aureus reduce peptidoglycan chain length and cause aberrant cell division. ACS Chem Biol 2013 0.84
75 Functional and structural analysis of a key region of the cell wall inhibitor moenomycin. ACS Chem Biol 2010 0.84
76 Chemoenzymatic formation of novel aminocoumarin antibiotics by the enzymes CouN1 and CouN7. Biochemistry 2007 0.83
77 Assembly of dimeric variants of coumermycins by tandem action of the four biosynthetic enzymes CouL, CouM, CouP, and NovN. Biochemistry 2004 0.82
78 Kinetic analysis of teicoplanin glycosyltransferases and acyltransferase reveal ordered tailoring of aglycone scaffold to reconstitute mature teicoplanin. J Am Chem Soc 2007 0.82
79 Installation of the pyrrolyl-2-carboxyl pharmacophore by CouN1 and CouN7 in the late biosynthetic steps of the aminocoumarin antibiotics clorobiocin and coumermycin A1. Biochemistry 2006 0.82
80 Using biological performance similarity to inform disaccharide library design. J Am Chem Soc 2009 0.81
81 Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A. J Am Chem Soc 2007 0.78
82 Overcoming degeneracy in carbohydrate recognition. Angew Chem Int Ed Engl 2003 0.76
83 Design and Synthesis of Functionalized Trisaccharides as p53-Peptide Mimics. Tetrahedron Lett 2010 0.75
84 Identification of a functionally unique family of penicillin-binding proteins. J Am Chem Soc 2017 0.75