Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision.

PubWeight™: 12.85‹?› | Rank: Top 0.1% | All-Time Top 10000

🔗 View Article (PMID 11105057)

Published in Genesis on January 09, 2001

Authors

A Novak1, C Guo, W Yang, A Nagy, C G Lobe

Author Affiliations

1: Cancer Research Division, Sunnybrook and Women's College Health Science Centre, Toronto, Ontario, Canada.

Articles citing this

(truncated to the top 100)

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol (2001) 31.56

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94

Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med (2007) 8.06

Pericytes regulate the blood-brain barrier. Nature (2010) 6.62

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest (2003) 6.44

Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc Natl Acad Sci U S A (2002) 5.54

Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell (2008) 4.90

Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons. Neuron (2011) 4.88

The cells and logic for mammalian sour taste detection. Nature (2006) 4.65

Adult mice generated from induced pluripotent stem cells. Nature (2009) 4.21

Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages. Immunity (2007) 4.17

The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron (2006) 4.12

Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus. Cell Stem Cell (2011) 4.08

Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res (2005) 4.08

Radial glia give rise to adult neural stem cells in the subventricular zone. Proc Natl Acad Sci U S A (2004) 3.91

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nat Neurosci (2008) 3.90

Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Curr Biol (2007) 3.76

STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J Neurosci (2008) 3.44

High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression. PLoS One (2008) 3.44

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain. Proc Natl Acad Sci U S A (2008) 3.44

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J Clin Invest (2007) 3.32

Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis. J Clin Invest (2008) 3.29

The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. Dev Cell (2008) 3.08

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer. Proc Natl Acad Sci U S A (2009) 3.08

Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metab (2010) 3.05

Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab (2007) 3.02

Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J Clin Invest (2005) 2.94

Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision. Neuron (2010) 2.91

Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PLoS One (2009) 2.89

Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells. Nature (2009) 2.87

Spinal cord injury reveals multilineage differentiation of ependymal cells. PLoS Biol (2008) 2.80

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci (2013) 2.71

Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses. PLoS One (2008) 2.69

Nf1 has an essential role in endothelial cells. Nat Genet (2002) 2.63

Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS Biol (2010) 2.60

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development (2008) 2.59

Melanopsin contributions to irradiance coding in the thalamo-cortical visual system. PLoS Biol (2010) 2.56

Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol (2008) 2.51

Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell (2013) 2.43

The role of insulin receptor substrate 2 in hypothalamic and beta cell function. J Clin Invest (2005) 2.40

Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool. Dev Biol (2008) 2.38

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. J Clin Invest (2006) 2.38

High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nat Neurosci (2011) 2.36

V3 spinal neurons establish a robust and balanced locomotor rhythm during walking. Neuron (2008) 2.35

GABAergic RIP-Cre neurons in the arcuate nucleus selectively regulate energy expenditure. Cell (2012) 2.34

The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron (2008) 2.33

Age-dependent fate and lineage restriction of single NG2 cells. Development (2011) 2.29

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria. Genes Dev (2007) 2.23

Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease. Am J Pathol (2013) 2.12

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation. J Clin Invest (2007) 2.09

Delta-like 4 is indispensable in thymic environment specific for T cell development. J Exp Med (2008) 2.02

Somitic origin of limb muscle satellite and side population cells. Proc Natl Acad Sci U S A (2006) 2.01

Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice. Am J Pathol (2009) 2.01

Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development. Mol Cell Biol (2006) 2.00

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J Exp Med (2008) 1.98

A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors. J Neurosci (2007) 1.94

Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes. Neuron (2015) 1.93

Nck proteins maintain the adult glomerular filtration barrier. J Am Soc Nephrol (2009) 1.92

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature (2011) 1.91

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Dev Cell (2010) 1.90

Dedifferentiation and proliferation of mammalian cardiomyocytes. PLoS One (2010) 1.89

Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity. Dev Biol (2008) 1.88

Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies. J Mol Cell Cardiol (2010) 1.88

Distinct origins and genetic programs of head muscle satellite cells. Dev Cell (2009) 1.86

gamma-Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina. Development (2008) 1.85

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice. Genesis (2008) 1.83

Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli. Am J Respir Cell Mol Biol (2005) 1.83

Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function. PLoS Biol (2007) 1.82

Ectopic retinal ON bipolar cell synapses in the OFF inner plexiform layer: contacts with dopaminergic amacrine cells and melanopsin ganglion cells. J Comp Neurol (2009) 1.82

Fate-restricted neural progenitors in the mammalian cerebral cortex. Science (2012) 1.77

Dual origin of mesenchymal stem cells contributing to organ growth and repair. Proc Natl Acad Sci U S A (2011) 1.77

Sonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates. Neuron (2010) 1.77

Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone. Proc Natl Acad Sci U S A (2005) 1.77

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors. EMBO J (2011) 1.75

Excitability and synaptic communication within the oligodendrocyte lineage. J Neurosci (2010) 1.74

SOX9 induces and maintains neural stem cells. Nat Neurosci (2010) 1.74

Generation of Cre-transgenic mice using Dlx1/Dlx2 enhancers and their characterization in GABAergic interneurons. Mol Cell Neurosci (2008) 1.72

Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun (2011) 1.69

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO J (2009) 1.68

Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex. Neuron (2008) 1.67

NG2-glia as multipotent neural stem cells: fact or fantasy? Neuron (2011) 1.67

Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci (2008) 1.67

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice. J Clin Invest (2010) 1.66

Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion. Genes Dev (2011) 1.63

Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation. J Cell Biol (2010) 1.60

Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis. Dev Cell (2008) 1.60

Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons. Cell Metab (2009) 1.59

Schwann cell-specific ablation of laminin gamma1 causes apoptosis and prevents proliferation. J Neurosci (2005) 1.58

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation. EMBO J (2010) 1.55

Stem cells for ischemic brain injury: a critical review. J Comp Neurol (2009) 1.53

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer. Nat Cell Biol (2017) 1.52

Lineage allocation and asymmetries in the early mouse embryo. Philos Trans R Soc Lond B Biol Sci (2003) 1.52

Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves. J Clin Invest (2010) 1.51

Gene expression in cortical interneuron precursors is prescient of their mature function. Cereb Cortex (2008) 1.51

Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource. Nat Commun (2012) 1.51

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes. J Clin Invest (2008) 1.50

Generation of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortex. Nat Protoc (2011) 1.49

Endothelial cells require STAT3 for protection against endotoxin-induced inflammation. J Exp Med (2003) 1.49

Molecular heterogeneity in the choroid plexus epithelium: the 22-member γ-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation. J Neurochem (2011) 1.48

Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos. Blood (2008) 1.47

Articles by these authors

CHARMM: the biomolecular simulation program. J Comput Chem (2009) 27.71

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature (1996) 18.47

Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). Science (1985) 12.75

Global burden of obesity in 2005 and projections to 2030. Int J Obes (Lond) (2008) 9.45

Promotion of trophoblast stem cell proliferation by FGF4. Science (1998) 8.02

Z/AP, a double reporter for cre-mediated recombination. Dev Biol (1999) 6.88

A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A (1998) 6.47

Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell (2001) 5.93

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49

Generating green fluorescent mice by germline transmission of green fluorescent ES cells. Mech Dev (1998) 5.21

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature (2000) 4.63

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat Med (1999) 4.33

Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc Natl Acad Sci U S A (1998) 3.88

Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression. Development (2000) 3.44

Essential role of Mash-2 in extraembryonic development. Nature (1994) 3.36

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. EMBO J (2001) 3.23

Hardness, softness, and the fukui function in the electronic theory of metals and catalysis. Proc Natl Acad Sci U S A (1985) 3.12

Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol (2001) 2.94

Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell (1999) 2.91

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. J Exp Med (1999) 2.81

Short-window spectral analysis of cortical event-related potentials by adaptive multivariate autoregressive modeling: data preprocessing, model validation, and variability assessment. Biol Cybern (2000) 2.81

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity. J Mol Biol (2001) 2.80

Long-term reconstitution of the mouse hematopoietic system by embryonic stem cell-derived fetal liver. Proc Natl Acad Sci U S A (1991) 2.66

The use of global and local molecular parameters for the analysis of the gas-phase basicity of amines. J Am Chem Soc (1986) 2.64

Imprinted X inactivation maintained by a mouse Polycomb group gene. Nat Genet (2001) 2.63

Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer. Br J Cancer (2007) 2.62

Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev Biol (1999) 2.59

Genome manipulation in embryonic stem cells. Philos Trans R Soc Lond B Biol Sci (1993) 2.50

Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair. Mol Cell (2001) 2.46

Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis. Cell (1998) 2.46

Genomic imprinting of Mash2, a mouse gene required for trophoblast development. Nat Genet (1995) 2.46

The orderly allocation of mesodermal cells to the extraembryonic structures and the anteroposterior axis during gastrulation of the mouse embryo. Development (1999) 2.45

Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4(-/-) embryos. Development (1997) 2.41

A survey of the genomic distribution of alpha satellite DNA on all the human chromosomes, and derivation of a new consensus sequence. Nucleic Acids Res (1991) 2.39

Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes. Mol Cell Biol (1995) 2.37

Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. Genes Dev (2000) 2.32

Human-proto-oncogene nucleotide sequences corresponding to the transforming region of simian sarcoma virus. Science (1984) 2.32

Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res (2000) 2.32

Reovirus as an oncolytic agent against experimental human malignant gliomas. J Natl Cancer Inst (2001) 2.27

Non-injection methods for the production of embryonic stem cell-embryo chimaeras. Nature (1993) 2.27

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase. Genes Dev (1999) 2.24

Survival among women with triple receptor-negative breast cancer and brain metastases. Ann Oncol (2009) 2.21

N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo. Mol Cell Biol (2001) 2.16

Non-invasive sexing of preimplantation stage mammalian embryos. Nat Genet (1998) 2.16

Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett (2001) 2.15

Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas. Cancer Res (2001) 2.13

A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharmacol Ther (2012) 2.12

Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system. Lab Invest (1999) 2.06

Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells. Genesis (2000) 2.05

A versatile synthetic dimerizer for the regulation of protein-protein interactions. Proc Natl Acad Sci U S A (1997) 2.04

The preparation and characterization of synaptic vesicles of high purity. Brain Res (1976) 2.00

Crystal structure of the Xrcc4 DNA repair protein and implications for end joining. EMBO J (2000) 1.94

Conservation and novelty in the evolution of cell adhesion and extracellular matrix genes. Science (2000) 1.93

Medium-chain acyl-CoA dehydrogenase deficiency in children with non-ketotic hypoglycemia and low carnitine levels. Pediatr Res (1983) 1.91

Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2. Mol Cell Biol (1997) 1.89

Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes. Science (1986) 1.88

Development and psychometric testing of a quality of recovery score after general anesthesia and surgery in adults. Anesth Analg (1999) 1.85

Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases. EMBO J (1998) 1.84

The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development (2001) 1.83

Linearly polarized emission from colloidal semiconductor quantum rods. Science (2001) 1.82

Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia. Clin Pharmacol Ther (2008) 1.82

Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial. J Thromb Haemost (2008) 1.81

mu Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality. Brain Res Mol Brain Res (1998) 1.78

Activation of human lung mast cells by monomeric immunoglobulin E. Eur Respir J (2005) 1.74

An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant cells of the mouse placenta. Genesis (2001) 1.73

Mash2 acts cell autonomously in mouse spongiotrophoblast development. Dev Biol (1997) 1.71

Genome engineering: the new mouse genetics. Nat Med (1995) 1.69

Long-term effects of a randomised trial of a 6-year lifestyle intervention in impaired glucose tolerance on diabetes-related microvascular complications: the China Da Qing Diabetes Prevention Outcome Study. Diabetologia (2010) 1.68

Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1. Mol Cell Biol (1996) 1.68

Density-functional theory of the electronic structure of molecules. Annu Rev Phys Chem (1995) 1.64

A genetically tractable model of human glioma formation. Cancer Res (2001) 1.63

Concordance of DMET plus genotyping results with those of orthogonal genotyping methods. Clin Pharmacol Ther (2012) 1.62

Fragile X gene instability: anchoring AGGs and linked microsatellites. Am J Hum Genet (1995) 1.61

Hypothalamic hormones and cancer. Front Neuroendocrinol (2001) 1.61

A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor. J Exp Med (1988) 1.61

A needle-puncture that helped to change the world of surgery. Homage to János Veres. Surg Endosc (2000) 1.56

The pharmacology of bimatoprost (Lumigan). Surv Ophthalmol (2001) 1.54

Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product. J Biol Chem (1995) 1.52

Factors influencing survival rate in adenoid cystic carcinoma of the salivary glands. Int J Oral Maxillofac Surg (1997) 1.52

Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and xenografted tumors. Breast Cancer Res Treat (2010) 1.50

A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1. J Biol Chem (1997) 1.50

Human ovarian cancers express somatostatin receptors. J Clin Endocrinol Metab (2000) 1.49

Elevated serum antibodies against insulin-like growth factor-binding protein-2 allow detecting early-stage cancers: evidences from glioma and colorectal carcinoma studies. Ann Oncol (2012) 1.49

Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion. J Biol Chem (1998) 1.47

Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. J Natl Cancer Inst (1999) 1.46

Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1. J Biol Chem (1997) 1.45

Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage. J Pathol (2013) 1.45

Aspartame is no more likely than placebo to cause urticaria/angioedema: results of a multicenter, randomized, double-blind, placebo-controlled, crossover study. J Allergy Clin Immunol (1993) 1.44

The Hamilton depression scale. Evaluation of objectivity using logistic models. Acta Psychiatr Scand (1981) 1.43

Loss of heterozygosity at 1p36 independently predicts for disease progression but not decreased overall survival probability in neuroblastoma patients: a Children's Cancer Group study. J Clin Oncol (2000) 1.42

Quantum mechanics simulation of protein dynamics on long timescale. Proteins (2001) 1.42

The metabolic effects of once daily extended-release metformin in patients with type 2 diabetes: a multicentre study. Int J Clin Pract (2008) 1.40

Site-directed mutagenesis of the hinge region of nisinZ and properties of nisinZ mutants. Appl Microbiol Biotechnol (2004) 1.40

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes. Diabetologia (2013) 1.39

Modeling the Pauli potential in the pair density functional theory. J Chem Phys (2008) 1.39

Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial. Diabet Med (2008) 1.37

Mechanisms of internalization of Staphylococcus aureus by cultured human osteoblasts. Infect Immun (1999) 1.37

Obesity, coronary heart disease risk factors and diabetes in Chinese: an approach to the criteria of obesity in the Chinese population. Obes Rev (2002) 1.37

PU box-binding transcription factors and a POU domain protein cooperate in the Epstein-Barr virus (EBV) nuclear antigen 2-induced transactivation of the EBV latent membrane protein 1 promoter. J Gen Virol (1995) 1.36