Published in Mol Biol Cell on June 01, 2005
AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling. Neuron (2007) 2.94
Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol Rev (2009) 2.53
Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP. EMBO J (2007) 1.88
AKAP signaling complexes in regulation of excitatory synaptic plasticity. Neuroscientist (2011) 1.52
Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling. Nat Struct Mol Biol (2012) 1.42
AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors. J Neurosci (2012) 1.32
A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1. Pain (2008) 1.31
AKAP150-anchored PKA activity is important for LTD during its induction phase. J Physiol (2008) 1.26
Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin. J Neurosci (2010) 1.22
Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice. PLoS One (2010) 1.21
AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors. J Biol Chem (2010) 1.19
Regulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complex. J Neurosci (2009) 1.19
Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability. J Biol Chem (2010) 1.10
AKAP79 selectively enhances protein kinase C regulation of GluR1 at a Ca2+-calmodulin-dependent protein kinase II/protein kinase C site. J Biol Chem (2008) 1.08
Cross-talk between calcium and protein kinase A in the regulation of cell migration. Curr Opin Cell Biol (2011) 1.03
Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms. J Neurosci (2012) 1.03
Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling. J Neurosci (2009) 1.00
AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension. Sci Signal (2014) 0.97
A spatiotemporally coordinated cascade of protein kinase C activation controls isoform-selective translocation. Mol Cell Biol (2006) 0.94
A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density. J Biol Chem (2011) 0.91
Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic Plasticity. J Biol Chem (2015) 0.86
Role of AKAP79/150 protein in β1-adrenergic receptor trafficking and signaling in mammalian cells. J Biol Chem (2013) 0.86
Adenylyl cyclase anchoring by a kinase anchor protein AKAP5 (AKAP79/150) is important for postsynaptic β-adrenergic signaling. J Biol Chem (2013) 0.86
PKA compartmentalization via AKAP220 and AKAP12 contributes to endothelial barrier regulation. PLoS One (2014) 0.82
A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases. Br J Pharmacol (2014) 0.81
Synaptic loss and retention of different classic cadherins with LTP-associated synaptic structural remodeling in vivo. Hippocampus (2010) 0.81
A variable cytoplasmic domain segment is necessary for γ-protocadherin trafficking and tubulation in the endosome/lysosome pathway. Mol Biol Cell (2011) 0.81
Capturing single L-type Ca(2+) channel function with optics. Biochim Biophys Acta (2012) 0.81
The contribution of AKAP5 in amylase secretion from mouse parotid acini. Am J Physiol Cell Physiol (2010) 0.79
The classic cadherins in synaptic specificity. Cell Adh Migr (2015) 0.78
Calcium's role as nuanced modulator of cellular physiology in the brain. Biochem Biophys Res Commun (2016) 0.77
Cadherin-based transsynaptic networks in establishing and modifying neural connectivity. Curr Top Dev Biol (2015) 0.77
Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning. Nat Neurosci (2017) 0.75
"Shaping" of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor. J Mol Signal (2012) 0.75
LTP and LTD: an embarrassment of riches. Neuron (2004) 15.48
Structural basis of long-term potentiation in single dendritic spines. Nature (2004) 11.50
Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses. Neuron (2004) 5.95
Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature (2000) 5.14
Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. Cell (2003) 4.58
Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nat Neurosci (2004) 4.57
PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nat Neurosci (2003) 4.55
The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell (2001) 4.32
Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nat Neurosci (2000) 4.10
The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions. Trends Biochem Sci (1995) 3.91
NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus. Neuron (1998) 3.86
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron (2003) 3.62
Cadherin regulates dendritic spine morphogenesis. Neuron (2002) 3.55
Regulation of E-cadherin/Catenin association by tyrosine phosphorylation. J Biol Chem (1999) 3.53
Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase. J Neurosci (2000) 3.10
Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex. Neuron (2000) 3.03
The ins and outs of E-cadherin trafficking. Trends Cell Biol (2004) 2.70
Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin. J Neurosci (1998) 2.55
The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones. J Cell Biol (1996) 2.49
Role of AMPA receptor endocytosis in synaptic plasticity. Nat Rev Neurosci (2001) 2.46
Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association. J Neurosci (2000) 2.34
Direct cadherin-activated cell signaling: a view from the plasma membrane. J Cell Biol (2002) 2.33
Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression. J Neurosci (2002) 2.31
Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function. Neuron (2002) 2.26
The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover. J Biol Chem (2000) 2.23
Stability of dendritic spines and synaptic contacts is controlled by alpha N-catenin. Nat Neurosci (2004) 2.21
IQGAP proteins are integral components of cytoskeletal regulation. EMBO Rep (2003) 2.17
A role for the cadherin family of cell adhesion molecules in hippocampal long-term potentiation. Neuron (1998) 2.16
Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons. J Neurosci (2003) 2.14
Increasing numbers of synaptic puncta during late-phase LTP: N-cadherin is synthesized, recruited to synaptic sites, and required for potentiation. Neuron (2000) 2.07
Molecular modification of N-cadherin in response to synaptic activity. Neuron (2000) 2.02
Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate. EMBO J (1998) 2.01
Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360. J Biol Chem (2002) 1.86
Imaging kinase--AKAP79--phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy. J Cell Biol (2002) 1.67
Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin. J Neurosci (2002) 1.64
Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion medium. J Cell Biol (1991) 1.57
Signaling complexes: junctions on the intracellular information super highway. Curr Biol (2002) 1.54
Cadherin activity is required for activity-induced spine remodeling. J Cell Biol (2004) 1.43
Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release. Proc Natl Acad Sci U S A (2001) 1.41
Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain. J Cell Biol (1996) 1.36
E-cadherin mediated cell adhesion recruits SAP97 into the cortical cytoskeleton. J Cell Sci (1998) 1.25
Orchestration of synaptic plasticity through AKAP signaling complexes. Neuropharmacology (2004) 1.20
The cytoplasmic face of cell contact sites. Curr Opin Struct Biol (2002) 1.14
Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin. J Biol Chem (2002) 1.14
Multiple functions for the cadherin/catenin complex during neuronal development. Neuropharmacology (2004) 1.05
Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97. J Biol Chem (2002) 1.00
Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin. J Biol Chem (1996) 0.97
Distinct regions of the cadherin cytoplasmic domain are essential for functional interaction with Galpha 12 and beta-catenin. J Biol Chem (2001) 0.94
Identification of an IQGAP1/AKAP79 complex in beta-cells. J Cell Biochem (2003) 0.90
Localization of the A kinase anchoring protein AKAP79 in the human hippocampus. Eur J Neurosci (2000) 0.86
Sorting out genes that regulate epithelial and neuronal polarity. Cell (1998) 0.79
AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Biol (2004) 6.97
The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature (2005) 3.82
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron (2003) 3.62
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Curr Biol (2004) 3.45
Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. Nat Cell Biol (2003) 3.26
Protein phosphorylation in signaling--50 years and counting. Trends Biochem Sci (2005) 3.19
The prevalence of cirrhosis and hepatocellular carcinoma in patients with human immunodeficiency virus infection. Hepatology (2013) 2.98
AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling. Neuron (2007) 2.94
Distinct enzyme combinations in AKAP signalling complexes permit functional diversity. Nat Cell Biol (2005) 2.84
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology. Nature (2006) 2.77
Molecular basis of AKAP specificity for PKA regulatory subunits. Mol Cell (2006) 2.33
Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression. J Neurosci (2002) 2.31
AKAP signaling complexes: getting to the heart of the matter. Trends Mol Med (2006) 2.29
AKAP mediated signal transduction. Annu Rev Pharmacol Toxicol (2002) 2.26
Interaction with AKAP79 modifies the cellular pharmacology of PKC. Mol Cell (2010) 2.22
Cost-effectiveness and population outcomes of general population screening for hepatitis C. Clin Infect Dis (2012) 2.19
AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists. Nat Neurosci (2003) 2.08
Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes. Mol Cell (2006) 2.05
A-kinase anchoring proteins take shape. Curr Opin Cell Biol (2007) 2.03
An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics. EMBO J (2006) 1.99
A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory. J Neurosci (2007) 1.97
Loss of AKAP150 perturbs distinct neuronal processes in mice. Proc Natl Acad Sci U S A (2008) 1.96
Retinal detachment and prophylaxis in type 1 Stickler syndrome. Ophthalmology (2007) 1.95
Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics. J Cell Biol (2002) 1.93
A-kinase anchoring proteins: from protein complexes to physiology and disease. IUBMB Life (2009) 1.89
Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice. Proc Natl Acad Sci U S A (2003) 1.86
Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360. J Biol Chem (2002) 1.86
The where's and when's of kinase anchoring. Trends Biochem Sci (2006) 1.83
AKAP-Lbc nucleates a protein kinase D activation scaffold. Mol Cell (2004) 1.81
Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring. Proc Natl Acad Sci U S A (2003) 1.80
Regulation of neuronal PKA signaling through AKAP targeting dynamics. Eur J Cell Biol (2006) 1.79
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling. Nat Cell Biol (2002) 1.77
Networking with AKAPs: context-dependent regulation of anchored enzymes. Mol Interv (2010) 1.69
Imaging kinase--AKAP79--phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy. J Cell Biol (2002) 1.67
Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract. FEBS Lett (2005) 1.66
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat Cell Biol (2010) 1.64
Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin. J Neurosci (2002) 1.64
AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circ Res (2013) 1.59
Trafficking of L-type calcium channels mediated by the postsynaptic scaffolding protein AKAP79. J Biol Chem (2002) 1.58
AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Mol Cell (2008) 1.57
cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold protein. J Neurosci (2006) 1.57
Prolonged incubation and extensive subculturing do not increase recovery of clinically significant microorganisms from standard automated blood cultures. Clin Infect Dis (2005) 1.57
Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome. Circ Res (2010) 1.55
Signaling complexes: junctions on the intracellular information super highway. Curr Biol (2002) 1.54
AKAP signaling complexes in regulation of excitatory synaptic plasticity. Neuroscientist (2011) 1.52
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ. Mol Cell (2011) 1.52
CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage. J Neurosci (2010) 1.49
Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor. J Biol Chem (2006) 1.48
Compartmentation of cyclic nucleotide signaling in the heart: the role of A-kinase anchoring proteins. Circ Res (2006) 1.48
PKA-phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex. Biochem J (2004) 1.47
Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A. Am J Physiol Cell Physiol (2011) 1.46
Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling. Nat Struct Mol Biol (2012) 1.42
Phospholipase C is required for changes in postsynaptic structure and function associated with NMDA receptor-dependent long-term depression. J Neurosci (2007) 1.36
AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors. J Neurosci (2012) 1.32
AKAP18 contains a phosphoesterase domain that binds AMP. J Mol Biol (2007) 1.31
Spatial restriction of PDK1 activation cascades by anchoring to mAKAPalpha. Mol Cell (2005) 1.29
CaMKII autonomy is substrate-dependent and further stimulated by Ca2+/calmodulin. J Biol Chem (2010) 1.28
AKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the beta1-adrenergic receptor promotes recycling and functional resensitization of the receptor. J Biol Chem (2006) 1.28
An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proc Natl Acad Sci U S A (2011) 1.27
Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo. Nat Cell Biol (2002) 1.27
The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain. Proc Natl Acad Sci U S A (2008) 1.27
A-kinase anchoring protein 79/150 facilitates the phosphorylation of GABA(A) receptors by cAMP-dependent protein kinase via selective interaction with receptor beta subunits. Mol Cell Neurosci (2003) 1.23
Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex. Proc Natl Acad Sci U S A (2011) 1.23
Orchestration of synaptic plasticity through AKAP signaling complexes. Neuropharmacology (2004) 1.20
AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors. J Biol Chem (2010) 1.19
Organization of beta-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes. J Cell Biol (2007) 1.19
Regulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complex. J Neurosci (2009) 1.19
Migratory songbirds disperse ticks across Canada, and first isolation of the Lyme disease spirochete, Borrelia burgdorferi, from the avian tick, Ixodes auritulus. J Parasitol (2005) 1.19
Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties. J Biol Chem (2010) 1.19
mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha. Sci Signal (2008) 1.16
Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein. Circ Res (2011) 1.16
Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation. Elife (2013) 1.15
E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis. EMBO J (2014) 1.14
Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. J Gen Physiol (2014) 1.10
Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc. J Biol Chem (2008) 1.08
Signal integration through blending, bolstering and bifurcating of intracellular information. Nat Struct Mol Biol (2010) 1.07
Intracellular targeting of protein kinases and phosphatases. Diabetes (2002) 1.06
Targeting of protein kinase A by muscle A kinase-anchoring protein (mAKAP) regulates phosphorylation and function of the skeletal muscle ryanodine receptor. J Biol Chem (2003) 1.05
AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency. EMBO Mol Med (2011) 1.05
High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides. Biochem J (2006) 1.04
Coordinated signal integration at the M-type potassium channel upon muscarinic stimulation. EMBO J (2012) 1.02
Bariatric surgery is associated with a reduction in major macrovascular and microvascular complications in moderately to severely obese patients with type 2 diabetes mellitus. J Am Coll Surg (2013) 1.02
A-kinase anchoring proteins and neuronal signaling mechanisms. Genes Dev (2003) 1.01
The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16). Biochem J (2012) 1.01
Dual specificity A-kinase anchoring proteins (AKAPs) contain an additional binding region that enhances targeting of protein kinase A type I. J Biol Chem (2008) 0.99
Induction of flexibility through protein-protein interactions. J Biol Chem (2003) 0.99
Anchored protein kinase A recruitment of active Rac GTPase. J Biol Chem (2011) 0.99
MyRIP anchors protein kinase A to the exocyst complex. J Biol Chem (2007) 0.98
Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation. Proc Natl Acad Sci U S A (2012) 0.98
AKAP signaling complexes: pointing towards the next generation of therapeutic targets? Trends Pharmacol Sci (2013) 0.98
Anchored phosphatases modulate glucose homeostasis. EMBO J (2012) 0.98
Characterization of A-kinase-anchoring disruptors using a solution-based assay. Biochem J (2006) 0.98
Patient acceptance of universal screening for hepatitis C virus infection. BMC Infect Dis (2011) 0.97
Gravin is a transitory effector of polo-like kinase 1 during cell division. Mol Cell (2012) 0.96
Clinical characterisation and molecular analysis of Wagner syndrome. Br J Ophthalmol (2006) 0.96
High efficiency of mutation detection in type 1 stickler syndrome using a two-stage approach: vitreoretinal assessment coupled with exon sequencing for screening COL2A1. Hum Mutat (2006) 0.94
Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. J Neurosci (2012) 0.94
A-kinase-anchoring proteins. J Cell Sci (2005) 0.93