Published in J Cell Biol on August 15, 2005
A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40
The tortoise and the hair: slow-cycling cells in the stem cell race. Cell (2009) 3.90
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet (2009) 2.07
New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. Proc Natl Acad Sci U S A (2008) 1.37
Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors. Dev Cell (2012) 1.34
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4. EMBO J (2006) 1.20
MicroRNA-205 controls neonatal expansion of skin stem cells by modulating the PI(3)K pathway. Nat Cell Biol (2013) 1.11
AKT-independent PI3-K signaling in cancer - emerging role for SGK3. Cancer Manag Res (2013) 0.99
Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK. J Biol Chem (2009) 0.96
The cycling hair follicle as an ideal systems biology research model. Exp Dermatol (2010) 0.95
Akt2 and SGK3 are both determinants of postnatal hair follicle development. FASEB J (2009) 0.83
Cancer Microenvironment: What Can We Learn from the Stem Cell Niche. Int J Mol Sci (2015) 0.81
Blunted IgE-mediated activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3. Am J Physiol Cell Physiol (2010) 0.79
The critical roles of serum/glucocorticoid-regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology. Am J Pathol (2006) 0.77
The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci (2017) 0.76
Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices. Cell (2017) 0.75
Emerging roles of transit-amplifying cells in tissue regeneration and cancer. Wiley Interdiscip Rev Dev Biol (2017) 0.75
Regulation of gastric acid secretion by the serum and glucocorticoid inducible kinase isoform SGK3. J Gastroenterol (2010) 0.75
Cellular survival: a play in three Akts. Genes Dev (1999) 17.05
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science (2002) 14.50
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell (1993) 10.36
Capturing and profiling adult hair follicle stem cells. Nat Biotechnol (2004) 10.35
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development (1999) 9.82
Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell (2000) 6.93
Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell (2001) 6.37
A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. J Invest Dermatol (2001) 6.12
Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev (1994) 6.07
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev (2003) 5.91
Controls of hair follicle cycling. Physiol Rev (2001) 5.49
Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes. Nature (1977) 4.90
The ErbB receptors and their role in cancer progression. Exp Cell Res (2003) 3.37
FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations. Cell (1994) 3.10
Molecular principles of hair follicle induction and morphogenesis. Bioessays (2005) 3.08
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev (1995) 2.99
Keratinocyte growth factor is required for hair development but not for wound healing. Genes Dev (1996) 2.82
Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation. J Cell Sci (1998) 2.78
PTEN: from pathology to biology. Trends Cell Biol (2003) 2.69
Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Biochem J (1999) 2.39
Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. Sci STKE (2001) 1.82
Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development (1999) 1.75
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res (2003) 1.75
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. Am J Pathol (1997) 1.62
Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity. Cell Physiol Biochem (2003) 1.60
Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion. Cancer Res (2000) 1.37
Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival. Curr Biol (2000) 1.36
Effects of insulin and insulin-like growth factors on cultured human hair follicles: IGF-I at physiologic concentrations is an important regulator of hair follicle growth in vitro. J Invest Dermatol (1994) 1.27
Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides. J Cell Biol (2001) 1.23
Angora mouse mutation: altered hair cycle, follicular dystrophy, phenotypic maintenance of skin grafts, and changes in keratin expression. Vet Pathol (1997) 1.21
Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle. Dev Dyn (1996) 1.19
Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate. Proc Natl Acad Sci U S A (2001) 1.16
Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development. Mol Cell Biol (2005) 1.12
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development. Mol Biol Cell (2004) 1.11
Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice. Oncogene (1997) 1.08
Effects of epidermal growth factor on hair growth in the mouse. J Endocrinol (1981) 1.00
Insulin-like growth factor 1 and hair growth. Dermatol Online J (1999) 0.98
Increased vibrissa growth in transgenic mice expressing insulin-like growth factor 1. J Invest Dermatol (1999) 0.94
Inhibition of wool growth in merino sheep following administration of mouse epidermal growth factor and a derivative. Aust J Biol Sci (1982) 0.85
Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice. Mol Carcinog (1999) 0.85
Apoptosis in wool follicles during mouse epidermal growth factor (mEGF)-induced catagen regression. J Invest Dermatol (1987) 0.84
Morphological changes in the skin and wool fibres of Merino sheep infused with mouse epidermal growth factor. Aust J Biol Sci (1983) 0.83
Regulation of cancer cell metabolism. Nat Rev Cancer (2011) 15.44
Defining the epithelial stem cell niche in skin. Science (2003) 14.93
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell (2002) 9.10
Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev Cancer (2006) 7.53
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature (2004) 7.21
Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature (2005) 6.67
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol (2003) 6.46
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet (2006) 6.30
Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science (2011) 5.87
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol (2007) 5.83
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med (2010) 5.68
A skin microRNA promotes differentiation by repressing 'stemness'. Nature (2008) 5.66
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell (2009) 5.51
A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell (2009) 5.40
Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis. Cell (2005) 5.37
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature (2005) 5.37
Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell (2008) 5.02
Sticky business: orchestrating cellular signals at adherens junctions. Cell (2003) 4.91
Links between signal transduction, transcription and adhesion in epithelial bud development. Nature (2003) 4.88
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
Modulation of oxidative stress as an anticancer strategy. Nat Rev Drug Discov (2013) 4.72
Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol (2002) 4.29
Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol (2005) 4.27
Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine. Cell Host Microbe (2009) 4.20
Dynamics between stem cells, niche, and progeny in the hair follicle. Cell (2011) 4.14
Epithelial stem cells: turning over new leaves. Cell (2007) 4.10
WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production. Immunity (2003) 4.07
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature (2012) 4.04
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell (2002) 4.01
Epidermal stem cells of the skin. Annu Rev Cell Dev Biol (2006) 3.92
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol (2008) 3.91
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature (2011) 3.90
Tcf3 governs stem cell features and represses cell fate determination in skin. Cell (2006) 3.88
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2006) 3.85
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc Natl Acad Sci U S A (2005) 3.83
NFATc1 balances quiescence and proliferation of skin stem cells. Cell (2008) 3.81
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes Dev (2003) 3.79
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell (2006) 3.79
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal. J Exp Med (2006) 3.78
Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables. Nat Cell Biol (2003) 3.77
Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer (2004) 3.76
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature (2002) 3.74
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med (2005) 3.70
Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol (2004) 3.70
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev (2005) 3.67
Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature (2011) 3.64
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology. Cell (2011) 3.61
Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature (2011) 3.56
Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes Dev (2002) 3.55
Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia. Cancer Cell (2007) 3.55
Caspase functions in cell death and disease. Cold Spring Harb Perspect Biol (2013) 3.55
Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev (2006) 3.51
A role for skin gammadelta T cells in wound repair. Science (2002) 3.51
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci U S A (2006) 3.41
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat Cell Biol (2006) 3.19
The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses. Nat Immunol (2003) 3.18
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proc Natl Acad Sci U S A (2007) 3.16
DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell (2005) 3.12
Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3. Hepatology (2015) 3.10
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell (2006) 3.10
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol (2002) 3.08
In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am J Physiol Lung Cell Mol Physiol (2003) 3.08
Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J Immunol (2003) 3.07
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol (2008) 3.07
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes Dev (2011) 2.97
GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev (2003) 2.97
The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell (2010) 2.97
Cytochrome c: functions beyond respiration. Nat Rev Mol Cell Biol (2008) 2.95
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
The role of cytokines in classical Hodgkin lymphoma. Blood (2002) 2.86
Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). Am J Respir Crit Care Med (2005) 2.86
Stem cells in the skin: waste not, Wnt not. Genes Dev (2003) 2.80
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell (2011) 2.80
Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. J Cell Biol (2007) 2.79
Alpha-catenin: at the junction of intercellular adhesion and actin dynamics. Nat Rev Mol Cell Biol (2004) 2.79
Lhx2 maintains stem cell character in hair follicles. Science (2006) 2.78
Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta. Proc Natl Acad Sci U S A (2004) 2.74
Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet (2003) 2.73
Metabolic targeting as an anticancer strategy: dawn of a new era? Sci STKE (2007) 2.71
Catenins: keeping cells from getting their signals crossed. Dev Cell (2006) 2.70
Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (2002) 2.69
Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways. Genes Dev (2006) 2.66
p120-catenin mediates inflammatory responses in the skin. Cell (2006) 2.66
ACF7: an essential integrator of microtubule dynamics. Cell (2003) 2.66
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol Cell (2012) 2.66
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol (2003) 2.65