Published in J Biol Chem on May 05, 2003
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Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome. Diabetes (2011) 1.82
miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2010) 1.75
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Regulation of nuclear translocation of HDAC3 by IkappaBalpha is required for tumor necrosis factor inhibition of peroxisome proliferator-activated receptor gamma function. J Biol Chem (2005) 1.63
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PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1. Nucl Recept Signal (2010) 0.98
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MicroRNA-494, upregulated by tumor necrosis factor-α, desensitizes insulin effect in C2C12 muscle cells. PLoS One (2013) 0.84
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Caffeic acid phenethyl ester preferentially enhanced radiosensitizing and increased oxidative stress in medulloblastoma cell line. Childs Nerv Syst (2008) 0.81
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Diacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes. J Lipid Res (2012) 0.78
Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol (2012) 0.78
Biglycan deletion alters adiponectin expression in murine adipose tissue and 3T3-L1 adipocytes. PLoS One (2012) 0.77
Effects of intravenous glucose and lipids on innate immune cell activation in healthy, obese, and type 2 diabetic subjects. Physiol Rep (2015) 0.77
The Ubiquitination of NF-κB Subunits in the Control of Transcription. Cells (2016) 0.75
Integrative Genomic Analyses Yield Cell-Cycle Regulatory Programs with Prognostic Value. Mol Cancer Res (2016) 0.75
MicroRNAs modulate hematopoietic lineage differentiation. Science (2003) 30.05
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med (2007) 8.18
Myogenic factors that regulate expression of muscle-specific microRNAs. Proc Natl Acad Sci U S A (2006) 6.19
Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA (2012) 5.15
Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system. Blood (2003) 4.91
MicroRNA-125b is a novel negative regulator of p53. Genes Dev (2009) 4.43
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci U S A (2002) 4.40
miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc Natl Acad Sci U S A (2007) 4.15
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci U S A (2004) 3.90
Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells. Nat Med (2006) 3.09
Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. Cancer Res (2007) 3.04
MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity. Diabetes (2009) 3.02
Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Blood (2008) 2.79
MicroRNAs as regulators of mammalian hematopoiesis. Semin Immunol (2005) 2.62
Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2. Nat Cell Biol (2008) 2.50
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44
Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells. Blood (2003) 2.42
From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood (2011) 2.42
ACRP30, a new hormone controlling fat and glucose metabolism. Eur J Pharmacol (2002) 2.31
Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways. J Biol Chem (2003) 2.29
MicroRNA miR-125b causes leukemia. Proc Natl Acad Sci U S A (2010) 2.29
Mir193b-365 is essential for brown fat differentiation. Nat Cell Biol (2011) 2.20
Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem (2002) 2.20
Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. Blood (2005) 2.17
Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Blood (2013) 2.12
Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. J Clin Invest (2004) 2.12
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells. Proc Natl Acad Sci U S A (2002) 2.08
MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets. Mol Cell Biol (2009) 2.08
A family of Acrp30/adiponectin structural and functional paralogs. Proc Natl Acad Sci U S A (2004) 2.06
Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation. Genes Dev (2011) 2.06
Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion. Blood (2005) 2.05
Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis. J Exp Med (2004) 1.98
Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha. Cytokine Growth Factor Rev (2003) 1.96
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance. Circ Res (2006) 1.95
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proc Natl Acad Sci U S A (2006) 1.92
Long noncoding RNAs regulate adipogenesis. Proc Natl Acad Sci U S A (2013) 1.90
Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking. Nature (2003) 1.88
Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep (2012) 1.82
Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab (2002) 1.82
Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proc Natl Acad Sci U S A (2003) 1.80
Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase). Biochem J (2002) 1.79
Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. FASEB J (2008) 1.77
Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes. Dev Cell (2002) 1.67
Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway. Blood (2005) 1.63
HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal. Blood (2010) 1.63
A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes. Mol Cell Proteomics (2002) 1.61
Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation. Blood (2002) 1.59
Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. J Biol Chem (2002) 1.58
Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients. J Lipid Res (2002) 1.56
Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you. Annu Rev Cell Dev Biol (2005) 1.55
Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. PLoS Genet (2011) 1.55
Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F. J Biol Chem (2007) 1.55
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. Proc Natl Acad Sci U S A (2011) 1.54
Cytokines regulating hematopoietic stem cell function. Curr Opin Hematol (2008) 1.54
Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes. J Biol Chem (2003) 1.45
Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes. Blood (2011) 1.43
The endoglin(positive) sca-1(positive) rhodamine(low) phenotype defines a near-homogeneous population of long-term repopulating hematopoietic stem cells. Immunity (2003) 1.42
Active conformation of the erythropoietin receptor: random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains. J Biol Chem (2006) 1.37
Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells. Stem Cells (2008) 1.36
Alpha4beta1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development. J Cell Biol (2007) 1.35
Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells. FASEB J (2010) 1.32
Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential. Stem Cells Dev (2011) 1.32
Down-regulation of Myc is essential for terminal erythroid maturation. J Biol Chem (2010) 1.30
An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity. Oncogene (2003) 1.29
Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance. Diabetes (2002) 1.29
Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP). J Biol Chem (2005) 1.29
Characterization of a heart-specific fatty acid transport protein. J Biol Chem (2003) 1.28
Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors. Blood (2004) 1.28
Formation of mammalian erythrocytes: chromatin condensation and enucleation. Trends Cell Biol (2011) 1.28
Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein. Nat Chem Biol (2012) 1.27
Model of human low-density lipoprotein and bound receptor based on cryoEM. Proc Natl Acad Sci U S A (2009) 1.27
Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. J Biol Chem (2003) 1.26
Medicine. Visfatin: a new adipokine. Science (2004) 1.26
Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts. Haematologica (2010) 1.25
AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation. Blood (2005) 1.25
Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor. J Biol Chem (2007) 1.24
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev (2012) 1.23
miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1. Genes Dev (2010) 1.23
Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A (2010) 1.22
A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. Cell Signal (2006) 1.20
The role of the adipocyte hormone adiponectin in cardiovascular disease. Curr Opin Pharmacol (2005) 1.19
Serum opacity factor unmasks human plasma high-density lipoprotein instability via selective delipidation and apolipoprotein A-I desorption. Biochemistry (2007) 1.18
Metabolic basis of HIV-lipodystrophy syndrome. Am J Physiol Endocrinol Metab (2002) 1.18
Small interfering RNA production by enzymatic engineering of DNA (SPEED). Proc Natl Acad Sci U S A (2004) 1.17
Mice deleted for fatty acid transport protein 5 have defective bile acid conjugation and are protected from obesity. Gastroenterology (2006) 1.16
Targeting microRNAs in obesity. Expert Opin Ther Targets (2009) 1.14
Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation. Blood (2010) 1.12
Acyl-CoA synthetase 2 overexpression enhances fatty acid internalization and neurite outgrowth. J Biol Chem (2004) 1.12
Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo. Proc Natl Acad Sci U S A (2005) 1.12
Low-density lipoprotein in hypercholesterolemic human plasma induces vascular endothelial cell apoptosis by inhibiting fibroblast growth factor 2 transcription. Circulation (2003) 1.12
miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221. Blood (2009) 1.11
Adiponectin regulates expression of hepatic genes critical for glucose and lipid metabolism. Proc Natl Acad Sci U S A (2012) 1.10
ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling. Blood (2009) 1.09
Pathogenesis of the erythroid failure in Diamond Blackfan anaemia. Br J Haematol (2009) 1.08
ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors. Nature (2013) 1.08
Endogenous K-ras signaling in erythroid differentiation. Cell Cycle (2007) 1.08