Published in Infect Immun on November 01, 2005
Origins and virulence mechanisms of uropathogenic Escherichia coli. Exp Mol Pathol (2008) 2.81
Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract. Proc Natl Acad Sci U S A (2007) 2.56
Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52
Complicated catheter-associated urinary tract infections due to Escherichia coli and Proteus mirabilis. Clin Microbiol Rev (2008) 2.45
Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15
A murine model of urinary tract infection. Nat Protoc (2009) 2.15
Host-pathogen interactions in urinary tract infection. Nat Rev Urol (2010) 1.94
Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection. Sci Transl Med (2013) 1.88
Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathog (2010) 1.88
Role of motility in the colonization of uropathogenic Escherichia coli in the urinary tract. Infect Immun (2005) 1.80
Importance of the ebp (endocarditis- and biofilm-associated pilus) locus in the pathogenesis of Enterococcus faecalis ascending urinary tract infection. J Infect Dis (2007) 1.74
Impact of the RNA chaperone Hfq on the fitness and virulence potential of uropathogenic Escherichia coli. Infect Immun (2008) 1.65
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection. Infect Immun (2012) 1.64
Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection. Proc Natl Acad Sci U S A (2015) 1.62
Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55
QseC-mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenic Escherichia coli. Mol Microbiol (2009) 1.47
Waging war against uropathogenic Escherichia coli: winning back the urinary tract. Infect Immun (2009) 1.46
Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection. Infect Immun (2011) 1.36
Epigenetic regulation of the nitrosative stress response and intracellular macrophage survival by extraintestinal pathogenic Escherichia coli. Mol Microbiol (2012) 1.35
Global gene expression profiling of the asymptomatic bacteriuria Escherichia coli strain 83972 in the human urinary tract. Infect Immun (2006) 1.32
A central metabolic circuit controlled by QseC in pathogenic Escherichia coli. Mol Microbiol (2011) 1.26
complex interplay between type 1 fimbrial expression and flagellum-mediated motility of uropathogenic Escherichia coli. J Bacteriol (2007) 1.24
In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infect Immun (2006) 1.24
Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis. Infect Immun (2010) 1.19
Roles of the extraintestinal pathogenic Escherichia coli ZnuACB and ZupT zinc transporters during urinary tract infection. Infect Immun (2008) 1.19
α-Intercalated cells defend the urinary system from bacterial infection. J Clin Invest (2014) 1.18
Escherichia coli biofilms have an organized and complex extracellular matrix structure. MBio (2013) 1.17
The innate immune response during urinary tract infection and pyelonephritis. Pediatr Nephrol (2013) 1.10
Multiple genes repress motility in uropathogenic Escherichia coli constitutively expressing type 1 fimbriae. J Bacteriol (2008) 1.04
Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor. Proc Natl Acad Sci U S A (2013) 1.03
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob Agents Chemother (2012) 1.02
Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors. J Bacteriol (2012) 1.02
Streptozocin-induced diabetic mouse model of urinary tract infection. Infect Immun (2008) 1.02
Trade-off between bile resistance and nutritional competence drives Escherichia coli diversification in the mouse gut. PLoS Genet (2011) 1.01
PapX, a P fimbrial operon-encoded inhibitor of motility in uropathogenic Escherichia coli. Infect Immun (2008) 1.00
Genetic basis of persister tolerance to aminoglycosides in Escherichia coli. MBio (2015) 0.99
Flagella allow uropathogenic Escherichia coli ascension into murine kidneys. Int J Med Microbiol (2007) 0.99
Immune activation and suppression by group B streptococcus in a murine model of urinary tract infection. Infect Immun (2011) 0.99
Conjugative plasmid transfer and adhesion dynamics in an Escherichia coli biofilm. Appl Environ Microbiol (2009) 0.98
Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli. Infect Immun (2012) 0.97
Flagella promote Escherichia coli K1 association with and invasion of human brain microvascular endothelial cells. Infect Immun (2007) 0.96
Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli. MBio (2014) 0.94
Kinetics of uropathogenic Escherichia coli metapopulation movement during urinary tract infection. MBio (2012) 0.94
Genetic determinants of swimming motility in the squid light-organ symbiont Vibrio fischeri. Microbiologyopen (2013) 0.93
The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain. PLoS One (2013) 0.93
Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis. EBioMedicine (2014) 0.93
NGAL-Siderocalin in kidney disease. Biochim Biophys Acta (2012) 0.92
Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection. PLoS Pathog (2015) 0.90
Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation. Am J Physiol Renal Physiol (2013) 0.89
Cloning of fimH and fliC and expression of the fusion protein FimH/FliC from Uropathogenic Escherichia coli (UPEC) isolated in Iran. Iran J Microbiol (2012) 0.89
Pleiotropic roles of uvrY on biofilm formation, motility and virulence in uropathogenic Escherichia coli CFT073. PLoS One (2013) 0.88
Inhibition of Escherichia coli CFT073 fliC expression and motility by cranberry materials. Appl Environ Microbiol (2011) 0.88
Aberrant community architecture and attenuated persistence of uropathogenic Escherichia coli in the absence of individual IHF subunits. PLoS One (2012) 0.87
Genetic analysis of the role of yfiR in the ability of Escherichia coli CFT073 to control cellular cyclic dimeric GMP levels and to persist in the urinary tract. Infect Immun (2013) 0.86
Survival of uropathogenic Escherichia coli in the murine urinary tract is dependent on OmpR. Microbiology (2009) 0.86
Virulence and Fitness Determinants of Uropathogenic Escherichia coli. Microbiol Spectr (2015) 0.85
Impact of host age and parity on susceptibility to severe urinary tract infection in a murine model. PLoS One (2014) 0.84
Catch-bond mechanism of the bacterial adhesin FimH. Nat Commun (2016) 0.82
The role of H4 flagella in Escherichia coli ST131 virulence. Sci Rep (2015) 0.82
Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity. MBio (2015) 0.82
The UbiI (VisC) Aerobic Ubiquinone Synthase Is Required for Expression of Type 1 Pili, Biofilm Formation, and Pathogenesis in Uropathogenic Escherichia coli. J Bacteriol (2016) 0.79
Determining the relative contribution and hierarchy of hha and qseBC in the regulation of flagellar motility of Escherichia coli O157:H7. PLoS One (2014) 0.78
A conserved PapB family member, TosR, regulates expression of the uropathogenic Escherichia coli RTX nonfimbrial adhesin TosA while conserved LuxR family members TosE and TosF suppress motility. Infect Immun (2014) 0.78
Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections. Microbiol Spectr (2016) 0.77
The complex interplay among bacterial motility and virulence factors in different Escherichia coli infections. Eur J Clin Microbiol Infect Dis (2014) 0.76
A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease. Nat Microbiol (2016) 0.76
Reproducible gene targeting in recalcitrant Escherichia coli isolates. BMC Res Notes (2011) 0.75
Brighter Fluorescent Derivatives of UTI89 Utilizing a Monomeric vGFP. Pathogens (2016) 0.75
Biofilm formation on biotic and abiotic surfaces in the presence of antimicrobials by Escherichia coli Isolates from cases of bovine mastitis. Appl Environ Microbiol (2014) 0.75
Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease. PLoS Pathog (2017) 0.75
Fur (Ferric uptake regulator) represses adhesion to, invasion of, and intracellular bacterial community (IBC) formation within bladder epithelial cells and motility in uropathogenic Escherichia coli (UPEC). Infect Immun (2016) 0.75
Association of O-Antigen Serotype with the Magnitude of Initial Systemic Cytokine Responses and Persistence in the Urinary Tract. J Bacteriol (2016) 0.75
Novel vaccine antigen combinations elicit protective immune responses against Escherichia coli sepsis. Vaccine (2015) 0.75
Immunity to uropathogens: the emerging roles of inflammasomes. Nat Rev Urol (2017) 0.75
LIPOPOLYSACCHARIDE DOMAINS MODULATE UROVIRULENCE. Infect Immun (2016) 0.75
The histidine residue of QseC is required for canonical signaling between QseB and PmrB in uropathogenic Escherichia coli. J Bacteriol (2017) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A (2000) 96.90
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. J Bacteriol (1995) 46.37
FACS-optimized mutants of the green fluorescent protein (GFP). Gene (1996) 24.12
Genetic analysis of Escherichia coli biofilm formation: roles of flagella, motility, chemotaxis and type I pili. Mol Microbiol (1998) 10.07
Genetic analysis of the ompB locus in Escherichia coli K-12. J Mol Biol (1981) 8.18
Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. Science (1998) 8.16
Intracellular bacterial biofilm-like pods in urinary tract infections. Science (2003) 7.10
Conditional-replication, integration, excision, and retrieval plasmid-host systems for gene structure-function studies of bacteria. J Bacteriol (2001) 5.87
Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants. Mol Microbiol (2003) 5.31
Ascending, unobstructed urinary tract infection in mice caused by pyelonephritogenic Escherichia coli of human origin. Infect Immun (1983) 5.10
Type 1 pilus-mediated bacterial invasion of bladder epithelial cells. EMBO J (2000) 5.03
Identification of phosphate starvation-inducible genes in Escherichia coli K-12 by DNA sequence analysis of psi::lacZ(Mu d1) transcriptional fusions. J Bacteriol (1990) 5.02
Coupling of flagellar gene expression to flagellar assembly in Salmonella enterica serovar typhimurium and Escherichia coli. Microbiol Mol Biol Rev (2000) 4.86
Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection. Infect Immun (2001) 4.82
Bacterial motility on a surface: many ways to a common goal. Annu Rev Microbiol (2003) 4.78
Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12
Transcriptome of uropathogenic Escherichia coli during urinary tract infection. Infect Immun (2004) 3.28
Modulation of flagellar expression in Escherichia coli by acetyl phosphate and the osmoregulator OmpR. J Bacteriol (1995) 3.06
Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses. Proc Natl Acad Sci U S A (2000) 2.98
Development and maturation of Escherichia coli K-12 biofilms. Mol Microbiol (2003) 2.86
Multiple control of flagellum biosynthesis in Escherichia coli: role of H-NS protein and the cyclic AMP-catabolite activator protein complex in transcription of the flhDC master operon. J Bacteriol (1999) 2.80
Role of chemotaxis in the association of motile bacteria with intestinal mucosa: in vitro studies. Infect Immun (1981) 2.76
The flagella of enteropathogenic Escherichia coli mediate adherence to epithelial cells. Mol Microbiol (2002) 2.75
Development and dynamics of Pseudomonas sp. biofilms. J Bacteriol (2000) 2.72
Regulation of production of type 1 pili among urinary tract isolates of Escherichia coli. Infect Immun (1986) 2.65
The etiology of urinary tract infection: traditional and emerging pathogens. Am J Med (2002) 2.59
Epidemiology of urinary tract infections: transmission and risk factors, incidence, and costs. Infect Dis Clin North Am (2003) 2.47
An improved GFP cloning cassette designed for prokaryotic transcriptional fusions. Gene (1997) 2.45
Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella. J Immunol (2003) 2.43
Bacterial pili: molecular mechanisms of pathogenesis. Curr Opin Microbiol (2000) 2.43
DnaK, DnaJ, and GrpE are required for flagellum synthesis in Escherichia coli. J Bacteriol (1992) 2.28
Regulation cascade of flagellar expression in Gram-negative bacteria. FEMS Microbiol Rev (2003) 2.22
Type 1 fimbriae and extracellular polysaccharides are preeminent uropathogenic Escherichia coli virulence determinants in the murine urinary tract. Mol Microbiol (2002) 2.18
Biofilm formation and interaction with the surfaces of gallstones by Salmonella spp. Infect Immun (2002) 2.09
Role of motility in the colonization of uropathogenic Escherichia coli in the urinary tract. Infect Immun (2005) 1.80
Adverse conditions which cause lack of flagella in Escherichia coli. J Bacteriol (1993) 1.76
Proteus mirabilis genes that contribute to pathogenesis of urinary tract infection: identification of 25 signature-tagged mutants attenuated at least 100-fold. Infect Immun (2004) 1.76
High-affinity interaction between gram-negative flagellin and a cell surface polypeptide results in human monocyte activation. Infect Immun (2000) 1.70
Genetic and molecular characterization of the polar flagellum of Vibrio parahaemolyticus. J Bacteriol (1995) 1.69
Variation in expression of the Haemophilus influenzae HMW adhesins: a prokaryotic system reminiscent of eukaryotes. Proc Natl Acad Sci U S A (1999) 1.60
Severe oxidative stress causes inactivation of DnaK and activation of the redox-regulated chaperone Hsp33. Mol Cell (2005) 1.60
Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8. Cell Microbiol (2002) 1.54
Ultrastructure of Proteus mirabilis swarmer cell rafts and role of swarming in catheter-associated urinary tract infection. Infect Immun (2004) 1.50
TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. Am J Physiol Gastrointest Liver Physiol (2003) 1.38
Genetic system for reversible integration of DNA constructs and lacZ gene fusions into the Escherichia coli chromosome. Plasmid (2000) 1.33
Molecular epidemiology of Escherichia coli mediated urinary tract infections. Front Biosci (2003) 1.30
Repression of bacterial motility by a novel fimbrial gene product. EMBO J (2001) 1.30
Overexpresssion of a Legionella pneumophila homologue of the E. coli regulator csrA affects cell size, flagellation, and pigmentation. Int J Med Microbiol (2001) 1.29
Inactivation of the flagellin gene of Salmonella enterica serotype enteritidis strongly reduces invasion into differentiated Caco-2 cells. FEMS Microbiol Lett (2000) 1.21
Regulation of bacterial motility in response to low pH in Escherichia coli: the role of H-NS protein. Microbiology (2002) 1.08
Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin. Infect Immun (2001) 1.03
Mannose-resistant Proteus-like fimbriae are produced by most Proteus mirabilis strains infecting the urinary tract, dictate the in vivo localization of bacteria, and contribute to biofilm formation. Infect Immun (2004) 1.03
Cell biology. Bacterial spelunkers. Science (2000) 0.87
Intracellular bacterial biofilm-like pods in urinary tract infections. Science (2003) 7.10
Role of Escherichia coli curli operons in directing amyloid fiber formation. Science (2002) 5.58
Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. Proc Natl Acad Sci U S A (2006) 5.13
Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12
The biology and future prospects of antivirulence therapies. Nat Rev Microbiol (2008) 3.83
Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med (2007) 3.54
Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract. Proc Natl Acad Sci U S A (2006) 3.36
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol (2002) 3.26
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69
Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54
Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52
Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili. Cell Microbiol (2007) 2.48
Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli. J Biol Chem (2001) 2.34
Morphological plasticity as a bacterial survival strategy. Nat Rev Microbiol (2008) 2.28
Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect Immun (2002) 2.20
Structural biology of the chaperone-usher pathway of pilus biogenesis. Nat Rev Microbiol (2009) 2.19
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17
Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med (2011) 2.16
Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15
A murine model of urinary tract infection. Nat Protoc (2009) 2.15
Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein. Mol Microbiol (2006) 2.14
Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation. Infect Immun (2006) 2.11
Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2003) 2.02
Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. Microbes Infect (2010) 1.95
Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Mol Microbiol (2005) 1.90
Fiber assembly by the chaperone-usher pathway. Biochim Biophys Acta (2004) 1.89
Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection. Sci Transl Med (2013) 1.88
Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathog (2010) 1.88
Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A (2006) 1.87
Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli. PLoS Pathog (2009) 1.83
Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. J Urol (2004) 1.82
Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Mol Cell (2006) 1.81
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. J Infect Dis (2013) 1.76
Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67
Functional genomic studies of uropathogenic Escherichia coli and host urothelial cells when intracellular bacterial communities are assembled. J Biol Chem (2007) 1.64
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection. Infect Immun (2012) 1.64
Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis. Trends Microbiol (2004) 1.62
The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58
Maturation of intracellular Escherichia coli communities requires SurA. Infect Immun (2006) 1.56
Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding. Proc Natl Acad Sci U S A (2009) 1.56
Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli. Infect Immun (2005) 1.55
Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55
Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection. Cell Host Microbe (2009) 1.51
Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder. Infect Immun (2013) 1.50
Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific. J Infect Dis (2012) 1.48
QseC-mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenic Escherichia coli. Mol Microbiol (2009) 1.47
A tale of two pili: assembly and function of pili in bacteria. Trends Microbiol (2010) 1.47
Urinary tract infection drives genome instability in uropathogenic Escherichia coli and necessitates translesion synthesis DNA polymerase IV for virulence. Virulence (2011) 1.43
Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF. Proc Natl Acad Sci U S A (2009) 1.43
Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J Med Chem (2010) 1.40
The Legionella pneumophila PilT homologue DotB exhibits ATPase activity that is critical for intracellular growth. J Bacteriol (2004) 1.39
Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. Cold Spring Harb Perspect Med (2013) 1.38
CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli. Infect Immun (2003) 1.38
LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis. Mol Microbiol (2007) 1.37
Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression. Infect Immun (2008) 1.36
Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection. Infect Immun (2011) 1.36
Epigenetic regulation of the nitrosative stress response and intracellular macrophage survival by extraintestinal pathogenic Escherichia coli. Mol Microbiol (2012) 1.35
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol (2005) 1.35
CsgE is a curli secretion specificity factor that prevents amyloid fibre aggregation. Mol Microbiol (2011) 1.34
Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli. Cell Microbiol (2002) 1.34
Beyond bacteria: a study of the enteric microbial consortium in extremely low birth weight infants. PLoS One (2011) 1.28
Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice. Infect Immun (2005) 1.26
A central metabolic circuit controlled by QseC in pathogenic Escherichia coli. Mol Microbiol (2011) 1.26
Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis. J Bacteriol (2002) 1.24
Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis. J Bacteriol (2009) 1.23
Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development. Infect Immun (2009) 1.23
Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity. J Med Chem (2010) 1.22
G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity. Cell Microbiol (2008) 1.22
A novel endogenous inhibitor of the secreted streptococcal NAD-glycohydrolase. PLoS Pathog (2005) 1.20
Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis. Infect Immun (2010) 1.19
Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infections. Infect Immun (2010) 1.19
Catalysis of protein folding by chaperones in pathogenic bacteria. Proc Natl Acad Sci U S A (2004) 1.18
Escherichia coli biofilms have an organized and complex extracellular matrix structure. MBio (2013) 1.17
Escherichia coli DegP protease cleaves between paired hydrophobic residues in a natural substrate: the PapA pilin. J Bacteriol (2002) 1.16
Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation. J Am Chem Soc (2012) 1.15
Interaction of uropathogenic Escherichia coli with host uroepithelium. Curr Opin Microbiol (2005) 1.13
Crystal structure of the P pilus rod subunit PapA. PLoS Pathog (2007) 1.11
Structural and energetic basis of folded-protein transport by the FimD usher. Nature (2013) 1.11
Host subversion by formation of intracellular bacterial communities in the urinary tract. Microbes Infect (2004) 1.11
Molecular variations in Klebsiella pneumoniae and Escherichia coli FimH affect function and pathogenesis in the urinary tract. Infect Immun (2008) 1.07
Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides. J Med Chem (2012) 1.05
Chaperone-subunit-usher interactions required for donor strand exchange during bacterial pilus assembly. J Bacteriol (2003) 1.04
Targeting virulence for antimicrobial chemotherapy. Curr Opin Pharmacol (2003) 1.03
Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor. Proc Natl Acad Sci U S A (2013) 1.03
P pilus assembly motif necessary for activation of the CpxRA pathway by PapE in Escherichia coli. J Bacteriol (2004) 1.02
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob Agents Chemother (2012) 1.02
Streptozocin-induced diabetic mouse model of urinary tract infection. Infect Immun (2008) 1.02
Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors. J Bacteriol (2012) 1.02
Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation. Proc Natl Acad Sci U S A (2013) 1.02
Sticky fibers and uropathogenesis: bacterial adhesins in the urinary tract. Future Microbiol (2006) 0.99
Virulence plasmid harbored by uropathogenic Escherichia coli functions in acute stages of pathogenesis. Infect Immun (2010) 0.99
Immune activation and suppression by group B streptococcus in a murine model of urinary tract infection. Infect Immun (2011) 0.99
Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections. Infect Immun (2012) 0.98