Published in Infect Immun on July 01, 2005
Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15
The UPEC pore-forming toxin α-hemolysin triggers proteolysis of host proteins to disrupt cell adhesion, inflammatory, and survival pathways. Cell Host Microbe (2012) 1.94
Host-pathogen interactions in urinary tract infection. Nat Rev Urol (2010) 1.94
Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo. Proc Natl Acad Sci U S A (2012) 1.84
Maturation of intracellular Escherichia coli communities requires SurA. Infect Immun (2006) 1.56
Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55
Waging war against uropathogenic Escherichia coli: winning back the urinary tract. Infect Immun (2009) 1.46
A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells. PLoS Pathog (2007) 1.41
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol (2005) 1.35
Role of Uropathogenic Escherichia coli Virulence Factors in Development of Urinary Tract Infection and Kidney Damage. Int J Nephrol (2012) 1.31
Silent mischief: bacteriophage Mu insertions contaminate products of Escherichia coli random mutagenesis performed using suicidal transposon delivery plasmids mobilized by broad-host-range RP4 conjugative machinery. J Bacteriol (2010) 1.30
Modulation of host innate immune response in the bladder by uropathogenic Escherichia coli. Infect Immun (2007) 1.29
Inactivation of host Akt/protein kinase B signaling by bacterial pore-forming toxins. Mol Biol Cell (2008) 1.26
In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infect Immun (2006) 1.24
Molecular basis of uropathogenic Escherichia coli evasion of the innate immune response in the bladder. Infect Immun (2008) 1.17
OmpA of uropathogenic Escherichia coli promotes postinvasion pathogenesis of cystitis. Infect Immun (2009) 1.08
Attenuation of human neutrophil migration and function by uropathogenic bacteria. Microbes Infect (2011) 1.07
TLR-mediated immune responses in the urinary tract. Curr Opin Microbiol (2008) 1.00
Roles of putative type II secretion and type IV pilus systems in the virulence of uropathogenic Escherichia coli. PLoS One (2009) 1.00
Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection. J Infect Dis (2012) 0.95
Uropathogenic Escherichia coli Suppresses the host inflammatory response via pathogenicity island genes sisA and sisB. Infect Immun (2009) 0.94
Cytotoxic necrotizing factor 1 and hemolysin from uropathogenic Escherichia coli elicit different host responses in the murine bladder. Infect Immun (2012) 0.93
Pseudomonas aeruginosa AES-1 exhibits increased virulence gene expression during chronic infection of cystic fibrosis lung. PLoS One (2011) 0.91
Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract. PLoS One (2013) 0.90
YbcL of uropathogenic Escherichia coli suppresses transepithelial neutrophil migration. Infect Immun (2012) 0.88
Components of SurA required for outer membrane biogenesis in uropathogenic Escherichia coli. PLoS One (2008) 0.87
Aberrant community architecture and attenuated persistence of uropathogenic Escherichia coli in the absence of individual IHF subunits. PLoS One (2012) 0.87
ATG16L1 deficiency in macrophages drives clearance of uropathogenic E. coli in an IL-1β-dependent manner. Mucosal Immunol (2015) 0.86
Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli. Mucosal Immunol (2015) 0.85
Estrogenic modulation of uropathogenic Escherichia coli infection pathogenesis in a murine menopause model. Infect Immun (2012) 0.84
Are you experienced? Understanding bladder innate immunity in the context of recurrent urinary tract infection. Curr Opin Infect Dis (2015) 0.84
Lactobacillus rhamnosus GR-1 enhances NF-kappaB activation in Escherichia coli-stimulated urinary bladder cells through TLR4. BMC Microbiol (2012) 0.83
Prevention of anti-microbial peptide LL-37-induced apoptosis and ATP release in the urinary bladder by a modified glycosaminoglycan. PLoS One (2013) 0.83
Subversion of Host Innate Immunity by Uropathogenic Escherichia coli. Pathogens (2016) 0.79
Quality assessment of treated tannery wastewater with special emphasis on pathogenic E. coli detection through serotyping. Environ Monit Assess (2007) 0.79
Role of glycolipids in the pathogenesis of Enterococcus faecalis urinary tract infection. PLoS One (2014) 0.78
Cellular immunity survey against urinary tract infection using pVAX/fimH cassette with mammalian and wild type codon usage as a DNA vaccine. Clin Exp Vaccine Res (2014) 0.78
Strengths and Limitations of Model Systems for the Study of Urinary Tract Infections and Related Pathologies. Microbiol Mol Biol Rev (2016) 0.78
Bacterial lysis liberates the neutrophil migration suppressor YbcL from the periplasm of uropathogenic Escherichia coli. Infect Immun (2014) 0.77
A Murine Model for Escherichia coli Urinary Tract Infection. Methods Mol Biol (2016) 0.77
Comparison of host response mechanisms evoked by extended spectrum beta lactamase (ESBL)--and non-ESBL-producing uropathogenic E. coli. BMC Microbiol (2013) 0.77
Lectin-Like Molecules of Lactobacillus rhamnosus GG Inhibit Pathogenic Escherichia coli and Salmonella Biofilm Formation. PLoS One (2016) 0.76
Dual ligand/receptor interactions activate urothelial defenses against uropathogenic E. coli. Sci Rep (2015) 0.76
Urothelial Generation and Regeneration in Development, Injury, and Cancer. Dev Dyn (2017) 0.75
The lectin-like protein 1 in Lactobacillus rhamnosus GR-1 mediates tissue-specific adherence to vaginal epithelium and inhibits urogenital pathogens. Sci Rep (2016) 0.75
High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300. Sci Rep (2016) 0.75
Association of O-Antigen Serotype with the Magnitude of Initial Systemic Cytokine Responses and Persistence in the Urinary Tract. J Bacteriol (2016) 0.75
The Adherent/invasive Escherichia coli (AIEC) Strain LF82 Invades and Persists in Human Prostate Cell LineRWPE-1 Activating a Strong Inflammatory Response. Infect Immun (2016) 0.75
LIPOPOLYSACCHARIDE DOMAINS MODULATE UROVIRULENCE. Infect Immun (2016) 0.75
Uropathogenic Escherichia coli-Associated Exotoxins. Microbiol Spectr (2016) 0.75
The complete genome sequence of Escherichia coli K-12. Science (1997) 84.27
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 37.15
Toll-like receptor signalling. Nat Rev Immunol (2004) 34.74
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol (1999) 16.86
Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria. J Bacteriol (1990) 15.13
Simultaneous identification of bacterial virulence genes by negative selection. Science (1995) 10.52
Identification of a sex-factor-affinity site in E. coli as gamma delta. Cold Spring Harb Symp Quant Biol (1981) 8.26
Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. Science (1998) 8.16
A toll-like receptor that prevents infection by uropathogenic bacteria. Science (2004) 5.26
Type 1 pilus-mediated bacterial invasion of bladder epithelial cells. EMBO J (2000) 5.03
Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection. Infect Immun (2001) 4.82
Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination. Science (1997) 4.57
Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science (2000) 4.22
Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity (2001) 3.27
The Gal(alpha 1-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract. Proc Natl Acad Sci U S A (1994) 3.02
Selective cytokine production by epithelial cells following exposure to Escherichia coli. Infect Immun (1993) 2.83
Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro. Infect Immun (1992) 2.82
SurA assists the folding of Escherichia coli outer membrane proteins. J Bacteriol (1996) 2.78
Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway. J Immunol (2002) 2.70
Regulation of production of type 1 pili among urinary tract isolates of Escherichia coli. Infect Immun (1986) 2.65
Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice. Infect Immun (1984) 2.35
Genetic evidence for parallel pathways of chaperone activity in the periplasm of Escherichia coli. J Bacteriol (2001) 2.33
Bacterial invasion augments epithelial cytokine responses to Escherichia coli through a lipopolysaccharide-dependent mechanism. J Immunol (2001) 2.27
Interleukin-6 response to deliberate colonization of the human urinary tract with gram-negative bacteria. Infect Immun (1991) 2.22
The SurA periplasmic PPIase lacking its parvulin domains functions in vivo and has chaperone activity. EMBO J (2001) 2.12
Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2003) 2.02
Uropathogenic Escherichia coli potentiates type 1 pilus-induced apoptosis by suppressing NF-kappaB. Infect Immun (2001) 1.66
Host-pathogen interactions: subversion and utilization of the NF-kappa B pathway during infection. Infect Immun (2002) 1.65
Elevated interleukin-8 levels in the urine of patients with urinary tract infections. Infect Immun (1993) 1.64
Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract. Cell Microbiol (2001) 1.50
Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa. Infect Immun (2004) 1.48
Lipopolysaccharides from periodontopathic bacteria Porphyromonas gingivalis and Capnocytophaga ochracea are antagonists for human toll-like receptor 4. Infect Immun (2002) 1.46
Yersinia outer protein P of Yersinia enterocolitica simultaneously blocks the nuclear factor-kappa B pathway and exploits lipopolysaccharide signaling to trigger apoptosis in macrophages. J Immunol (2001) 1.41
CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli. Infect Immun (2003) 1.38
The periplasmic molecular chaperone protein SurA binds a peptide motif that is characteristic of integral outer membrane proteins. J Biol Chem (2003) 1.37
Crystallographic structure of SurA, a molecular chaperone that facilitates folding of outer membrane porins. Structure (2002) 1.33
Structural requirements for TLR4-mediated LPS signalling: a biological role for LPS modifications. Microbes Infect (2003) 1.30
Localization of uroplakin Ia, the urothelial receptor for bacterial adhesin FimH, on the six inner domains of the 16 nm urothelial plaque particle. J Mol Biol (2002) 1.14
The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4. Infect Immun (2002) 1.14
Urinary interleukin-6 and interleukin-8 in children with urinary tract infection. Pediatr Nephrol (2000) 1.06
Interleukin 6 response to urinary tract infection in childhood. Pediatr Infect Dis J (1994) 0.92
Intracellular bacterial biofilm-like pods in urinary tract infections. Science (2003) 7.10
Role of Escherichia coli curli operons in directing amyloid fiber formation. Science (2002) 5.58
Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. Proc Natl Acad Sci U S A (2006) 5.13
Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A (2004) 4.12
The biology and future prospects of antivirulence therapies. Nat Rev Microbiol (2008) 3.83
Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med (2007) 3.54
Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract. Proc Natl Acad Sci U S A (2006) 3.36
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol (2002) 3.26
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69
Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54
Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol (2009) 2.52
Development of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili. Cell Microbiol (2007) 2.48
Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli. J Biol Chem (2001) 2.34
Morphological plasticity as a bacterial survival strategy. Nat Rev Microbiol (2008) 2.28
Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect Immun (2002) 2.20
Structural biology of the chaperone-usher pathway of pilus biogenesis. Nat Rev Microbiol (2009) 2.19
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17
Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med (2011) 2.16
Filamentation by Escherichia coli subverts innate defenses during urinary tract infection. Proc Natl Acad Sci U S A (2006) 2.15
A murine model of urinary tract infection. Nat Protoc (2009) 2.15
Secretion of curli fibre subunits is mediated by the outer membrane-localized CsgG protein. Mol Microbiol (2006) 2.14
Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation. Infect Immun (2006) 2.11
Uropathogenic Escherichia coli flagella aid in efficient urinary tract colonization. Infect Immun (2005) 2.10
Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli. Proc Natl Acad Sci U S A (2003) 2.02
Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. Microbes Infect (2010) 1.95
Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Mol Microbiol (2005) 1.90
Fiber assembly by the chaperone-usher pathway. Biochim Biophys Acta (2004) 1.89
Genomic diversity and fitness of E. coli strains recovered from the intestinal and urinary tracts of women with recurrent urinary tract infection. Sci Transl Med (2013) 1.88
Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection. PLoS Pathog (2010) 1.88
Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A (2006) 1.87
Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli. PLoS Pathog (2009) 1.83
Antibody responses and protection from pyelonephritis following vaccination with purified Escherichia coli PapDG protein. J Urol (2004) 1.82
Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Mol Cell (2006) 1.81
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. J Infect Dis (2013) 1.76
Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli. Annu Rev Microbiol (2010) 1.74
The siderophore yersiniabactin binds copper to protect pathogens during infection. Nat Chem Biol (2012) 1.68
Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67
Functional genomic studies of uropathogenic Escherichia coli and host urothelial cells when intracellular bacterial communities are assembled. J Biol Chem (2007) 1.64
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection. Infect Immun (2012) 1.64
Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis. Trends Microbiol (2004) 1.62
The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP. Proc Natl Acad Sci U S A (2005) 1.58
Maturation of intracellular Escherichia coli communities requires SurA. Infect Immun (2006) 1.56
Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding. Proc Natl Acad Sci U S A (2009) 1.56
Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiol Rev (2012) 1.55
Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection. Cell Host Microbe (2009) 1.51
Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific. J Infect Dis (2012) 1.48
QseC-mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenic Escherichia coli. Mol Microbiol (2009) 1.47
A tale of two pili: assembly and function of pili in bacteria. Trends Microbiol (2010) 1.47
Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF. Proc Natl Acad Sci U S A (2009) 1.43
Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J Med Chem (2010) 1.40
The Legionella pneumophila PilT homologue DotB exhibits ATPase activity that is critical for intracellular growth. J Bacteriol (2004) 1.39
Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era. Cold Spring Harb Perspect Med (2013) 1.38
CD14- and Toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli. Infect Immun (2003) 1.38
LeuX tRNA-dependent and -independent mechanisms of Escherichia coli pathogenesis in acute cystitis. Mol Microbiol (2007) 1.37
Utilization of an intracellular bacterial community pathway in Klebsiella pneumoniae urinary tract infection and the effects of FimK on type 1 pilus expression. Infect Immun (2008) 1.36
Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection. Infect Immun (2011) 1.36
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli. J Bacteriol (2005) 1.35
CsgE is a curli secretion specificity factor that prevents amyloid fibre aggregation. Mol Microbiol (2011) 1.34
Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli. Cell Microbiol (2002) 1.34
Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice. Infect Immun (2005) 1.26
A central metabolic circuit controlled by QseC in pathogenic Escherichia coli. Mol Microbiol (2011) 1.26
Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract. Kidney Int (2011) 1.25
Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis. J Bacteriol (2002) 1.24
Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis. J Bacteriol (2009) 1.23
Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development. Infect Immun (2009) 1.23
Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity. J Med Chem (2010) 1.22
G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity. Cell Microbiol (2008) 1.22
A novel endogenous inhibitor of the secreted streptococcal NAD-glycohydrolase. PLoS Pathog (2005) 1.20
Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis. Infect Immun (2010) 1.19
Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infections. Infect Immun (2010) 1.19
Catalysis of protein folding by chaperones in pathogenic bacteria. Proc Natl Acad Sci U S A (2004) 1.18
Escherichia coli biofilms have an organized and complex extracellular matrix structure. MBio (2013) 1.17
Escherichia coli DegP protease cleaves between paired hydrophobic residues in a natural substrate: the PapA pilin. J Bacteriol (2002) 1.16
Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation. J Am Chem Soc (2012) 1.15
Interaction of uropathogenic Escherichia coli with host uroepithelium. Curr Opin Microbiol (2005) 1.13
Structural and energetic basis of folded-protein transport by the FimD usher. Nature (2013) 1.11
Crystal structure of the P pilus rod subunit PapA. PLoS Pathog (2007) 1.11
Host subversion by formation of intracellular bacterial communities in the urinary tract. Microbes Infect (2004) 1.11
Molecular variations in Klebsiella pneumoniae and Escherichia coli FimH affect function and pathogenesis in the urinary tract. Infect Immun (2008) 1.07
Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides. J Med Chem (2012) 1.05
Chaperone-subunit-usher interactions required for donor strand exchange during bacterial pilus assembly. J Bacteriol (2003) 1.04
Targeting virulence for antimicrobial chemotherapy. Curr Opin Pharmacol (2003) 1.03
Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor. Proc Natl Acad Sci U S A (2013) 1.03
P pilus assembly motif necessary for activation of the CpxRA pathway by PapE in Escherichia coli. J Bacteriol (2004) 1.02
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrob Agents Chemother (2012) 1.02
Streptozocin-induced diabetic mouse model of urinary tract infection. Infect Immun (2008) 1.02
Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors. J Bacteriol (2012) 1.02
Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation. Proc Natl Acad Sci U S A (2013) 1.02
Cupric yersiniabactin is a virulence-associated superoxide dismutase mimic. ACS Chem Biol (2013) 1.01
Sticky fibers and uropathogenesis: bacterial adhesins in the urinary tract. Future Microbiol (2006) 0.99