Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population.

PubWeight™: 3.14‹?› | Rank: Top 1%

🔗 View Article (PMID 16301342)

Published in Circulation on November 21, 2005

Authors

Martin D Tobin1, Stuart M Raleigh, Stephen Newhouse, Peter Braund, Clare Bodycote, Jenny Ogleby, Deborah Cross, Jay Gracey, Saija Hayes, Terry Smith, Cathy Ridge, Mark Caulfield, Nuala A Sheehan, Patricia B Munroe, Paul R Burton, Nilesh J Samani

Author Affiliations

1: Department of Health Sciences, University of Leicester, Leicester, England.

Articles citing this

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95

Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet (2008) 7.33

Genomewide association studies of stroke. N Engl J Med (2009) 5.29

Genome-wide association studies: contribution of genomics to understanding blood pressure and essential hypertension. Curr Hypertens Rep (2010) 2.03

The WNKs: atypical protein kinases with pleiotropic actions. Physiol Rev (2011) 1.88

Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array. Hypertension (2010) 1.22

Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study. J Hypertens (2009) 1.03

Genetics of hypertension: from experimental animals to humans. Biochim Biophys Acta (2009) 1.00

Genetics of arterial hypertension and hypotension. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.97

Ambulatory monitoring in the genetics of psychosomatic medicine. Psychosom Med (2012) 0.94

Dissecting complex traits: recent advances in hypertension genomics. Genome Med (2009) 0.93

Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion. PLoS One (2009) 0.92

WNK kinases, renal ion transport and hypertension. Am J Nephrol (2008) 0.91

Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans. Hum Mutat (2011) 0.87

Genetic determinants of cardiometabolic risk: a proposed model for phenotype association and interaction. J Clin Lipidol (2012) 0.84

The Finnish Cardiovascular Study (FINCAVAS): characterising patients with high risk of cardiovascular morbidity and mortality. BMC Cardiovasc Disord (2006) 0.80

Comprehensive assessment of the association of WNK4 polymorphisms with hypertension: evidence from a meta-analysis. Sci Rep (2014) 0.79

Hypertension: the missing WNKs. Am J Physiol Renal Physiol (2016) 0.76

Essential hypertension: perspectives and future directions. J Hypertens (2012) 0.76

Lack of family-based association between common variations in WNK1 and blood pressure level. Med Sci Monit (2014) 0.75

Extracellular water and blood pressure in adults with growth hormone (GH) deficiency: a genotype-phenotype association study. PLoS One (2014) 0.75

A polymorphic 3'UTR element in ATP1B1 regulates alternative polyadenylation and is associated with blood pressure. PLoS One (2013) 0.75

Association of blood pressure with genetic variation in WNK kinases in a white European population. Circulation (2005) 0.75

Determinants of day-night difference in blood pressure, a comparison with determinants of daytime and night-time blood pressure. J Hum Hypertens (2016) 0.75

The CUL3/KLHL3-WNK-SPAK/OSR1 pathway as a target for antihypertensive therapy. Am J Physiol Renal Physiol (2016) 0.75

Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1. J Am Soc Nephrol (2017) 0.75

Articles by these authors

Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21

Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35

Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01

Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med (2007) 18.78

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet (2003) 17.34

Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92

Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet (2005) 12.92

2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J (2013) 12.73

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62

Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10

Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94

Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet (2008) 7.33

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16

Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure. Stat Med (2005) 6.99

Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet (2007) 6.57

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet (2012) 6.15

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81

Management of hypertension: summary of NICE guidance. BMJ (2011) 5.60

Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA (2009) 5.32

The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet (2004) 5.31

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet (2010) 5.31

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet (2011) 5.26

Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation (2008) 5.20

Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome. Lancet (2012) 5.16

New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12

White cell telomere length and risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol (2003) 5.04

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet (2009) 4.63

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42

Laparoscopic adjustable gastric banding in severely obese adolescents: a randomized trial. JAMA (2010) 4.33

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13

Cost-effectiveness of options for the diagnosis of high blood pressure in primary care: a modelling study. Lancet (2011) 4.12

Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10

Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88

Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87

Weekly paclitaxel improves pathologic complete remission in operable breast cancer when compared with paclitaxel once every 3 weeks. J Clin Oncol (2005) 3.83

Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ (2011) 3.65

Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Lancet Neurol (2010) 3.61

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55

Genome-wide mapping of human loci for essential hypertension. Lancet (2003) 3.53

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet (2011) 3.46

High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med (2002) 3.43

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40

Children with early-onset inflammatory bowel disease (IBD): analysis of a pediatric IBD consortium registry. J Pediatr (2005) 3.37

Mapping of a major locus that determines telomere length in humans. Am J Hum Genet (2004) 3.33