Published in Dev Biol on December 15, 2005
p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. Neuron (2008) 1.97
Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo. Am J Pathol (2006) 1.22
ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway. Proc Natl Acad Sci U S A (2010) 1.10
Neurotrophic effect of a novel TrkB agonist on retinal ganglion cells. Invest Ophthalmol Vis Sci (2009) 1.03
BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina. Mol Neurodegener (2011) 1.02
NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death. EMBO J (2009) 0.99
Imbalance of the nerve growth factor and its precursor as a potential biomarker for diabetic retinopathy. Biomed Res Int (2015) 0.88
Mutation of SALL2 causes recessive ocular coloboma in humans and mice. Hum Mol Genet (2014) 0.81
Nerve growth factor in diabetic retinopathy: beyond neurons. Expert Rev Ophthalmol (2014) 0.80
Neuronal programmed cell death-1 ligand expression regulates retinal ganglion cell number in neonatal and adult mice. J Neuroophthalmol (2012) 0.77
Glycyrrhizin improves p75NTR-associated sciatic nerve regeneration in a BALB/c mouse model. Exp Ther Med (2014) 0.77
Somatic tetraploidy in vertebrate neurons: Implications in physiology and pathology. Commun Integr Biol (2010) 0.76
Time-Dependent Nerve Growth Factor Signaling Changes in the Rat Retina During Optic Nerve Crush-Induced Degeneration of Retinal Ganglion Cells. Int J Mol Sci (2017) 0.75
Expression of Epiplakin1 in the developing and adult mouse retina. Jpn J Ophthalmol (2010) 0.75
A restricted cell population propagates glioblastoma growth after chemotherapy. Nature (2012) 8.88
Pten regulates neuronal arborization and social interaction in mice. Neuron (2006) 6.11
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell (2005) 5.51
Neurofibromas in NF1: Schwann cell origin and role of tumor environment. Science (2002) 5.08
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell (2009) 4.82
TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron (2008) 4.00
Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Res (2008) 3.99
Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J Neurosci (2009) 2.90
Malignant glioma: lessons from genomics, mouse models, and stem cells. Cell (2012) 2.85
Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell (2008) 2.84
Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Mol Cell Biol (2002) 2.65
Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell (2008) 2.65
Nf1 has an essential role in endothelial cells. Nat Genet (2002) 2.63
ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab (2006) 2.55
The molecular and genetic basis of neurological tumours. Nat Rev Cancer (2002) 2.41
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model. Neuron (2004) 2.38
Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biol Psychiatry (2006) 2.36
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. Cancer Res (2003) 2.30
Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron. Hum Mol Genet (2003) 2.24
TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses. J Neurosci (2005) 2.21
Inducible gene deletion in astroglia and radial glia--a valuable tool for functional and lineage analysis. Glia (2006) 2.19
Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. J Neurosci (2002) 2.16
Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas. Cell Stem Cell (2009) 2.12
Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex. Neuron (2003) 2.11
The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker. Proc Natl Acad Sci U S A (2006) 2.11
Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb. Dev Cell (2004) 2.07
PTEN dosage is essential for neurofibroma development and malignant transformation. Proc Natl Acad Sci U S A (2009) 2.07
Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial. Lancet Oncol (2012) 1.95
Testis determination requires insulin receptor family function in mice. Nature (2003) 1.94
Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. Proc Natl Acad Sci U S A (2005) 1.93
Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation. Development (2005) 1.85
Pleiotropic role for MYCN in medulloblastoma. Genes Dev (2010) 1.84
The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons. J Neurosci (2004) 1.82
Development of a steroidogenic factor 1/Cre transgenic mouse line. Genesis (2006) 1.69
A crucial role for Olig2 in white matter astrocyte development. Development (2007) 1.60
Functional changes of glial glutamate transporter GLT-1 during ischemia: an in vivo study in the hippocampal CA1 of normal mice and mutant mice lacking GLT-1. J Neurosci (2003) 1.58
The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma. J Clin Invest (2007) 1.57
Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biol Psychiatry (2008) 1.55
Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury. J Neurosci (2007) 1.54
The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell (2008) 1.54
CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell (2013) 1.53
Six1 controls patterning of the mouse otic vesicle. Development (2003) 1.53
mRNA expression of ephrins and Eph receptor tyrosine kinases in the neonatal and adult mouse central nervous system. J Neurosci Res (2003) 1.53
miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. PLoS One (2011) 1.52
Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. Hum Mol Genet (2006) 1.48
The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells. Prog Retin Eye Res (2005) 1.47
Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (2006) 1.43
Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia. Neuropsychopharmacology (2008) 1.43
PTEN signaling in autism spectrum disorders. Curr Opin Neurobiol (2012) 1.43
Temporally regulated expression of Cre recombinase in neural stem cells. Genesis (2005) 1.38
Molecular regulation of visual system development: more than meets the eye. Genes Dev (2007) 1.37
Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis. J Neurosci (2012) 1.34
Vasopressin V1a and V1b receptors: from molecules to physiological systems. Physiol Rev (2012) 1.33
Neurotrophin-dependent dendritic filopodial motility: a convergence on PI3K signaling. J Neurosci (2008) 1.32
Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. J Neurosci (2004) 1.31
Inducible site-specific recombination in neural stem/progenitor cells. Genesis (2009) 1.31
Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Mol Cell Biol (2005) 1.31
Multiple roles for neurofibromin in skeletal development and growth. Hum Mol Genet (2007) 1.29
Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury. J Neurosci (2011) 1.29
Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia. J Biol Chem (2004) 1.28
Genetic modeling of gliomas in mice: new tools to tackle old problems. Glia (2011) 1.28
Inhibition of glial cell activation ameliorates the severity of experimental autoimmune encephalomyelitis. Neurosci Res (2007) 1.27
Maternal microchimerism in underlying pathogenesis of biliary atresia: quantification and phenotypes of maternal cells in the liver. Pediatrics (2008) 1.27
13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice. Proc Natl Acad Sci U S A (2004) 1.26
bFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healing. PLoS One (2010) 1.23
A critical role for dorsal progenitors in cortical myelination. J Neurosci (2006) 1.22
Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo. Am J Pathol (2006) 1.22
Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage. J Comp Neurol (2006) 1.22
Climbing fiber activation of EAAT4 transporters and kainate receptors in cerebellar Purkinje cells. J Neurosci (2004) 1.21
CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse. Dev Biol (2006) 1.20
Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type? FASEB J (2009) 1.18
Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract. Peptides (2002) 1.16
High-density presynaptic transporters are required for glutamate removal from the first visual synapse. Neuron (2006) 1.16
Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. J Exp Med (2012) 1.15
Spectroscopic visualization of vortex flows using dye-containing nanofibers. Angew Chem Int Ed Engl (2007) 1.15
ATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiation. Clin Cancer Res (2013) 1.15
The glutamate-aspartate transporter GLAST mediates glutamate uptake at inner hair cell afferent synapses in the mammalian cochlea. J Neurosci (2006) 1.13
From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development. Proc Natl Acad Sci U S A (2006) 1.13
Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate. Development (2003) 1.12
Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF. Mol Neurodegener (2009) 1.10
A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice. Brain Res (2007) 1.09
Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle. Genes Dev (2011) 1.08
Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors. Mol Cell Neurosci (2003) 1.08
Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex. Proc Natl Acad Sci U S A (2010) 1.07
Cryotherapy influences joint laxity and position sense of the healthy knee joint. Arch Phys Med Rehabil (2003) 1.07
The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons. Genes Dev (2005) 1.06
Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice. Blood (2006) 1.06
Epidermal growth factor receptor signaling pathways are associated with tumorigenesis in the Nf1:p53 mouse tumor model. Cancer Res (2002) 1.06
Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration. Nat Commun (2011) 1.06
Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Res (2011) 1.05