Published in Respir Res on December 16, 2005
Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. J Clin Invest (2008) 2.24
Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. J Immunol (2009) 2.05
Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2009) 1.90
RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism. Am J Respir Crit Care Med (2011) 1.49
CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity. Am J Pathol (2007) 1.26
Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice. Am J Respir Crit Care Med (2010) 1.08
Autoimmunity in chronic obstructive pulmonary disease: clinical and experimental evidence. Expert Rev Clin Immunol (2012) 1.07
Cigarette smoke promotes dendritic cell accumulation in COPD; a Lung Tissue Research Consortium study. Respir Res (2010) 1.07
Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation. Respir Res (2010) 1.03
The composition of cigarette smoke determines inflammatory cell recruitment to the lung in COPD mouse models. Clin Sci (Lond) (2014) 0.93
Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice. Respir Res (2007) 0.89
Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells? Respir Res (2008) 0.89
Tobacco smoke induced COPD/emphysema in the animal model-are we all on the same page? Front Physiol (2013) 0.89
Oxidative stress-mediated iNKT-cell activation is involved in COPD pathogenesis. Mucosal Immunol (2013) 0.87
Functional characterization of T cell populations in a mouse model of chronic obstructive pulmonary disease. J Immunol (2012) 0.86
Role of the tachykinin NK1 receptor in a murine model of cigarette smoke-induced pulmonary inflammation. Respir Res (2009) 0.85
Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice. BMC Pulm Med (2008) 0.85
Plasmacytoid dendritic cells prevent cigarette smoke and Chlamydophila pneumoniae-induced Th2 inflammatory responses. Am J Respir Cell Mol Biol (2009) 0.84
Cationic nanocarriers induce cell necrosis through impairment of Na(+)/K(+)-ATPase and cause subsequent inflammatory response. Cell Res (2015) 0.83
Different regulation of cigarette smoke induced inflammation in upper versus lower airways. Respir Res (2010) 0.82
Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner. Respir Res (2010) 0.80
Impaired transcriptional response of the murine heart to cigarette smoke in the setting of high fat diet and obesity. Chem Res Toxicol (2013) 0.79
Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice. Clin Sci (Lond) (2015) 0.79
IL-17A and serum amyloid A are elevated in a cigarette smoke cessation model associated with the persistence of pigmented macrophages, neutrophils and activated NK cells. PLoS One (2014) 0.77
Immune-mediated inflammation in the pathogenesis of emphysema: insights from mouse models. Cell Tissue Res (2017) 0.75
TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease. Sci Rep (2016) 0.75
PPARγ in emphysema: blunts the damage and triggers repair? J Clin Invest (2014) 0.75
Dendritic cells and the control of immunity. Nature (1998) 56.54
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med (2001) 27.83
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet (1997) 25.40
The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med (2004) 17.08
A severe combined immunodeficiency mutation in the mouse. Nature (1983) 13.99
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science (1997) 8.19
Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J (2003) 6.23
Burden and clinical features of chronic obstructive pulmonary disease (COPD). Lancet (2004) 6.17
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell (1995) 5.58
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet (2004) 5.16
The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination. Cell (1988) 4.34
Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J Exp Med (2001) 3.90
CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1998) 3.69
An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med (2004) 3.12
Evidence of functional lymphocytes in some (leaky) scid mice. J Exp Med (1988) 3.09
Cytotoxic T lymphocytes: all roads lead to death. Nat Rev Immunol (2002) 3.01
Severity of airflow limitation is associated with severity of airway inflammation in smokers. Am J Respir Crit Care Med (1998) 2.62
Alveolar inflammation and its relation to emphysema in smokers. Am J Respir Crit Care Med (1995) 2.24
Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells. Am J Respir Crit Care Med (1997) 2.12
Measurement of pulmonary emphysema. Am Rev Respir Dis (1967) 1.97
Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur Respir J (2005) 1.81
Primary human alveolar type II epithelial cell chemokine release: effects of cigarette smoke and neutrophil elastase. Am J Respir Cell Mol Biol (2004) 1.78
Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur Respir J (2001) 1.68
Cellular and molecular mechanisms in chronic obstructive pulmonary disease: an overview. Clin Exp Allergy (2004) 1.58
Chronic obstructive pulmonary disease. Inflammation of small airways and lung parenchyma. Am J Respir Crit Care Med (1999) 1.56
Destructive index: a measurement of lung parenchymal destruction in smokers. Am Rev Respir Dis (1985) 1.45
Airway epithelial cells, cytokines, and pollutants. Am J Respir Crit Care Med (1999) 1.25
Strain-dependent leakiness of mice with severe combined immune deficiency. J Immunol (1993) 1.20
The biology of the SCID mutation. Immunol Today (1989) 1.19
Marked alveolar apoptosis/proliferation imbalance in end-stage emphysema. Respir Res (2005) 1.13
Matrix metalloproteinase-12 and cathepsin D expression in pulmonary macrophages and dendritic cells of cigarette smoke-exposed mice. Int Arch Allergy Immunol (2005) 1.12
Inflammatory cell profiles and T-lymphocyte subsets in chronic obstructive pulmonary disease and severe persistent asthma. Clin Exp Allergy (2004) 0.89
Variation of CD8+ T-lymphocytes around the bronchial internal perimeter in chronic bronchitis. Eur Respir J (2003) 0.81
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
Mediastinoscopy vs endosonography for mediastinal nodal staging of lung cancer: a randomized trial. JAMA (2010) 4.08
Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med (2014) 3.50
Corticosteroids and the risk of atrial fibrillation. Arch Intern Med (2006) 3.28
Endosonography vs conventional bronchoscopy for the diagnosis of sarcoidosis: the GRANULOMA randomized clinical trial. JAMA (2013) 3.13
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res (2006) 2.40
Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2007) 2.26
New insights into the immunology of chronic obstructive pulmonary disease. Lancet (2011) 2.23
Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial. Thorax (2013) 2.12
Endosonography for mediastinal nodal staging of clinical N1 non-small cell lung cancer: a prospective multicenter study. Chest (2015) 2.00
Activation of the WNT/β-catenin pathway attenuates experimental emphysema. Am J Respir Crit Care Med (2010) 1.94
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax (2012) 1.88
Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study. Am J Respir Crit Care Med (2012) 1.87
Severe asthma in adults: what are the important questions? J Allergy Clin Immunol (2007) 1.85
Identification and characterization of human pulmonary dendritic cells. Am J Respir Cell Mol Biol (2004) 1.66
Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 1.63
EBUS-TBNA for the clarification of PET positive intra-thoracic lymph nodes-an international multi-centre experience. J Thorac Oncol (2009) 1.60
Chronic obstructive pulmonary disease and cerebral microbleeds. The Rotterdam Study. Am J Respir Crit Care Med (2013) 1.57
Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice. J Immunol (2006) 1.55
Leptin as regulator of pulmonary immune responses: involvement in respiratory diseases. Pulm Pharmacol Ther (2013) 1.54
Role of activin-A in cigarette smoke-induced inflammation and COPD. Eur Respir J (2013) 1.52
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet (2012) 1.52
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med (2012) 1.49
Matrix metalloproteinase-9 deficiency impairs cellular infiltration and bronchial hyperresponsiveness during allergen-induced airway inflammation. Am J Pathol (2002) 1.45
MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 1.42
Matrix metalloproteinase-9-mediated dendritic cell recruitment into the airways is a critical step in a mouse model of asthma. J Immunol (2003) 1.35
Different roles for human lung dendritic cell subsets in pulmonary immune defense mechanisms. Am J Respir Cell Mol Biol (2006) 1.30
Matrix metalloproteinases in asthma and COPD. Curr Opin Pharmacol (2005) 1.27
Prevalence, incidence, and lifetime risk for the development of COPD in the elderly: the Rotterdam study. Chest (2009) 1.21
Prolonged inhaled allergen exposure can induce persistent tolerance. Am J Respir Cell Mol Biol (2007) 1.20
Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation. J Immunol (2007) 1.17
Dendritic cells in chronic obstructive pulmonary disease: new players in an old game. Am J Respir Crit Care Med (2008) 1.15
Matrix metalloproteinases -8, -9 and -12 in smokers and patients with stage 0 COPD. Int J Chron Obstruct Pulmon Dis (2007) 1.15
Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study. Thorax (2013) 1.13
NLRP3/caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation. J Immunol (2011) 1.13
Matrix metalloproteinase-12 and cathepsin D expression in pulmonary macrophages and dendritic cells of cigarette smoke-exposed mice. Int Arch Allergy Immunol (2005) 1.12
Murine TLR4 is implicated in cigarette smoke-induced pulmonary inflammation. Int Arch Allergy Immunol (2006) 1.12
Short-term cigarette smoke exposure enhances allergic airway inflammation in mice. Am J Respir Crit Care Med (2005) 1.09
C-reactive protein levels, haplotypes, and the risk of incident chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 1.08
The role of ChemR23 in the induction and resolution of cigarette smoke-induced inflammation. J Immunol (2011) 1.04
Statins, systemic inflammation and risk of death in COPD: the Rotterdam study. Pulm Pharmacol Ther (2012) 1.04
Extending the understanding of sensory neuropeptides. Eur J Pharmacol (2006) 1.03
Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice. J Immunol (2010) 1.03
Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation. Respir Res (2010) 1.03
Comparison of acute inflammatory and chronic structural asthma-like responses between C57BL/6 and BALB/c mice. Int Arch Allergy Immunol (2009) 1.02
Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD. Respir Res (2010) 1.01
Extrapulmonary manifestations of chronic obstructive pulmonary disease in a mouse model of chronic cigarette smoke exposure. Am J Respir Cell Mol Biol (2008) 1.00
Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice. Am J Respir Cell Mol Biol (2009) 1.00
Targeting interleukin-4 in asthma: lost in translation? Am J Respir Cell Mol Biol (2012) 0.99
EUS-FNA of enlarged necrotic lymph nodes may cause infectious mediastinitis. J Thorac Oncol (2008) 0.98