Published in Cell Cycle on January 16, 2006
Cell cycle regulation of DNA replication. Annu Rev Genet (2007) 3.80
Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication. Genes Dev (2012) 1.66
Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev (2006) 1.49
Geminin is partially localized to the centrosome and plays a role in proper centrosome duplication. Biol Cell (2009) 0.89
Cdc6 is required for meiotic spindle assembly in Xenopus oocytes. Cell Cycle (2012) 0.76
Proteomic characterization of the human centrosome by protein correlation profiling. Nature (2003) 8.74
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal (2010) 8.61
Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol (2004) 7.22
The Polo kinase Plk4 functions in centriole duplication. Nat Cell Biol (2005) 5.84
Plk4-induced centriole biogenesis in human cells. Dev Cell (2007) 5.68
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet (2006) 5.36
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science (2002) 4.94
Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J (2002) 4.54
Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat Cell Biol (2003) 4.31
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol Biol Cell (2003) 4.28
Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell (2007) 3.98
Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol (2007) 3.88
PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell (2007) 3.80
Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol (2002) 3.69
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene (2005) 3.64
Phosphoproteome analysis of the human mitotic spindle. Proc Natl Acad Sci U S A (2006) 3.56
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
Cell cycle regulation of central spindle assembly. Nature (2004) 3.27
HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Curr Biol (2006) 3.21
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol (2003) 3.12
Aurora kinases link chromosome segregation and cell division to cancer susceptibility. Curr Opin Genet Dev (2004) 2.96
Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. Genes Dev (2007) 2.92
Control of centriole length by CPAP and CP110. Curr Biol (2009) 2.67
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase. Nat Cell Biol (2004) 2.63
Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1. Nat Cell Biol (2007) 2.54
Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2. J Cell Biol (2004) 2.44
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication. EMBO J (2002) 2.41
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat Cell Biol (2005) 2.41
Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. EMBO Rep (2002) 2.40
Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Dev Cell (2005) 2.40
Rootletin forms centriole-associated filaments and functions in centrosome cohesion. J Cell Biol (2005) 2.38
Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. Mol Biol Cell (2007) 2.38
The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex. EMBO J (2003) 2.31
Proteome analysis of the human mitotic spindle. Mol Cell Proteomics (2004) 2.31
Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes Cells (2002) 2.28
Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation. Nature (2005) 2.26
Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science (2013) 2.25
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biol Open (2012) 2.23
Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev Cell (2003) 2.18
The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Mol Biol Cell (2004) 2.17
Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2. EMBO J (2006) 2.14
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J (2011) 2.14
Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting. Mol Biol Cell (2005) 2.09
KIF14 and citron kinase act together to promote efficient cytokinesis. J Cell Biol (2006) 2.06
Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell (2006) 1.94
The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics (2010) 1.91
Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma (2007) 1.78
Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. J Cell Sci (2007) 1.78
Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. EMBO J (2009) 1.76
Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation. J Cell Sci (2010) 1.74
The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles. J Cell Sci (2002) 1.73
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. EMBO J (2003) 1.67
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. J Cell Biol (2009) 1.64
Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1. J Biol Chem (2002) 1.63
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal (2011) 1.62
Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission. J Cell Sci (2006) 1.62
Cell-cycle-regulated expression of STIL controls centriole number in human cells. J Cell Sci (2012) 1.60
The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biol (2010) 1.60
Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora. Chromosoma (2008) 1.60
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. J Cell Biol (2007) 1.59
Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59
Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes Dev (2005) 1.57
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. J Cell Sci (2013) 1.55
Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages. J Proteome Res (2009) 1.53
Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. J Biol Chem (2002) 1.47
A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Mol Biol Cell (2005) 1.45
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. J Cell Sci (2010) 1.42
Centrosome-associated NDR kinase regulates centrosome duplication. Mol Cell (2007) 1.37
Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. J Cell Biol (2005) 1.34
Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma (2009) 1.33
Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1. Oncogene (2003) 1.33
Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. Chromosoma (2004) 1.30
Sgt1 is required for human kinetochore assembly. EMBO Rep (2004) 1.30
Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. J Cell Sci (2010) 1.28
Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions. Genes Dev (2003) 1.27
Cytostatic factor: an activity that puts the cell cycle on hold. J Cell Sci (2006) 1.27
Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases. Mol Cell Biol (2005) 1.26
Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. J Cell Sci (2005) 1.25
The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes Dev (2012) 1.23
The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. J Cell Biol (2002) 1.19
Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint. EMBO J (2011) 1.19
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. Mol Biol Cell (2008) 1.19
Inhibition of centrosome separation after DNA damage: a role for Nek2. Radiat Res (2004) 1.18
Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A. J Cell Biol (2013) 1.13
The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle. Curr Biol (2008) 1.13
Structural and functional organization of the Ska complex, a key component of the kinetochore-microtubule interface. Mol Cell (2012) 1.11
Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects. EMBO Rep (2005) 1.10
Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction. J Cell Biol (2012) 1.09
Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis. Anal Chem (2008) 1.06
SUMO-dependent regulation of centrin-2. J Cell Sci (2009) 1.06
Comparative conservation analysis of the human mitotic phosphoproteome. Bioinformatics (2008) 1.05
Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET. J Cell Sci (2012) 1.03
Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1. PLoS One (2011) 1.00
Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. J Mol Biol (2006) 0.99
M-phase MELK activity is regulated by MPF and MAPK. Cell Cycle (2006) 0.97
On the regulation, function, and localization of the DNA-dependent ATPase PICH. Chromosoma (2012) 0.96
Regulation of Aurora-A kinase on the mitotic spindle. Chromosoma (2003) 0.96
The histone chaperone Asf1 is dispensable for direct de novo histone deposition in Xenopus egg extracts. Chromosoma (2007) 0.91
Evaluation of data-dependent and -independent mass spectrometric workflows for sensitive quantification of proteins and phosphorylation sites. J Proteome Res (2014) 0.91