Molecular cloning of the white locus region of Drosophila melanogaster using a large transposable element.

PubWeight™: 2.04‹?› | Rank: Top 2%

🔗 View Article (PMID 16453411)

Published in EMBO J on January 01, 1982

Authors

M L Goldberg1, R Paro, W J Gehring

Author Affiliations

1: Abteilung Zellbiologie, Biozentrum der Universität Basel, CH-4056 Basel, Switzerland.

Articles citing this

Complete nucleotide sequence of the Drosophila transposable element copia: homology between copia and retroviral proteins. Mol Cell Biol (1985) 5.44

The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucleic Acids Res (1987) 4.92

Molecular structure of a somatically unstable transposable element in Drosophila. Proc Natl Acad Sci U S A (1986) 2.77

Microdissection and cloning of the white locus and the 3B1-3C2 region of the Drosophila X chromosome. EMBO J (1983) 2.74

Transcription of the white locus in Drosophila melanogaster. Proc Natl Acad Sci U S A (1983) 2.69

Transcription of the Drosophila white locus and some of its mutants. EMBO J (1984) 2.59

Unequal crossing-over associated with asymmetrical synapsis between nomadic elements in the Drosophila melanogaster genome. Proc Natl Acad Sci U S A (1983) 2.52

Functional analysis of the white gene of Drosophila by P-factor-mediated transformation. EMBO J (1984) 1.87

Partial revertants of the transposable element-associated suppressible allele white-apricot in Drosophila melanogaster: structures and responsiveness to genetic modifiers. Genetics (1988) 1.75

The Lighten up (Lip) gene of Drosophila melanogaster, a modifier of retroelement expression, position effect variegation and white locus insertion alleles. Genetics (1994) 1.58

Structure and genomic organization of I elements involved in I-R hybrid dysgenesis in Drosophila melanogaster. Nucleic Acids Res (1988) 1.41

Developmental expression of the white locus of Drosophila melanogaster. EMBO J (1984) 1.38

Transposition rates of movable genetic elements in Drosophila melanogaster. Proc Natl Acad Sci U S A (1990) 1.34

A reexamination of spreading of position-effect variegation in the white-roughest region of Drosophila melanogaster. Genetics (2000) 1.25

Interaction of the Enhancer of white-apricot with transposable element alleles at the white locus in Drosophila melanogaster. Genetics (1989) 1.22

Molecular analysis of large transposable elements carrying the white locus of Drosophila melanogaster. EMBO J (1983) 1.16

Interactions between WHITE Genes Carried by a Large Transposing Element and the ZESTE Allele in DROSOPHILA MELANOGASTER. Genetics (1986) 1.16

Molecular lesions associated with white gene mutations induced by I-R hybrid dysgenesis in Drosophila melanogaster. EMBO J (1984) 1.14

Molecular cloning, germ-line transformation, and transcriptional analysis of the zeste locus of Drosophila melanogaster. Proc Natl Acad Sci U S A (1986) 1.10

Effects of the maleless mutation on X and autosomal gene expression in Drosophila melanogaster. Genetics (1994) 1.09

Molecular cloning of suppressor of sable, a Drosophila melanogaster transposon-mediated suppressor. Mol Cell Biol (1986) 1.01

Characterization of the FB-NOF transposable element of Drosophila melanogaster. Genetics (1990) 0.99

The molecular structure of TE146 and its derivatives in Drosophila melanogaster. Genetics (1991) 0.98

The instability of the TE-like mutation Dp(2:2)GYL of Drosophila melanogaster is intimately associated with the hobo element. EMBO J (1987) 0.91

Mosaic suppressor, a gene in Drosophila that modifies retrotransposon expression and interacts with zeste. Genetics (1994) 0.86

Repair of UV-induced pyrimidine dimers in the individual genes Gart, Notch and white from Drosophila melanogaster cell lines. Nucleic Acids Res (1991) 0.83

FB elements can promote exon shuffling: a promoter-less white allele can be reactivated by FB mediated transposition in Drosophila melanogaster. Mol Genet Genomics (2004) 0.81

An Eye on Trafficking Genes: Identification of Four Eye Color Mutations in Drosophila. G3 (Bethesda) (2016) 0.75

Articles cited by this

Screening lambdagt recombinant clones by hybridization to single plaques in situ. Science (1977) 83.82

Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75

The isolation of structural genes from libraries of eucaryotic DNA. Cell (1978) 37.13

A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster. Cell (1974) 27.33

Charon phages: safer derivatives of bacteriophage lambda for DNA cloning. Science (1977) 20.27

Plasmid screening at high colony density. Gene (1980) 16.47

The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl-paper. Anal Biochem (1980) 14.73

Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method. Cell (1981) 11.51

Novel bacteriophage lambda cloning vector. Proc Natl Acad Sci U S A (1980) 8.97

Allelic pairing and gene regulation: A model for the zeste-white interaction in Drosophila melanogaster. Proc Natl Acad Sci U S A (1979) 6.57

Repeated gene families in Drosophila melanogaster. Cold Spring Harb Symp Quant Biol (1978) 5.85

Nucleic acid hybridization to the DNA of cytological preparations. Methods Cell Biol (1975) 4.98

SEX LIMITED INHERITANCE IN DROSOPHILA. Science (1910) 4.19

In vitro packaging of lambda Dam vectors and their use in cloning DNA fragments. Methods Enzymol (1979) 3.82

A copy of the copia transposable element is very tightly linked to the Wa allele at the white locus of D. melanogaster. Cell (1981) 2.99

Genetic duplication in the white-split interval of the X chromosome in Drosophila melanogaster. Chromosoma (1972) 2.89

Formation of duplication-deficiency products by asymmetrical exchange within a complex locus of Drosophila melanogaster. Proc Natl Acad Sci U S A (1961) 2.81

Unusual structure of the FB family of transposable elements in Drosophila. Cell (1981) 2.64

Putative non-reciprocal crossing over in Drosophila melanogaster. Z Vererbungsl (1959) 2.35

Cytogenetic studies on the white locus in Drosophila melanogaster. Genetics (1966) 2.25

Isolation of a hybrid plasmid with homologous sequences to a transposing element of Drosophila melanogaster. Cell (1980) 2.23

Eucaryotic transposable genetic elements with inverted terminal repeats. Cell (1980) 2.20

Cytogenetic fine structure and chromosomal localization of the white gene in Drosophila melanogaster. Nat New Biol (1973) 2.20

Derivation-dependent distribution of insertion sites for a Drosophila transposon. Cold Spring Harb Symp Quant Biol (1981) 1.83

Two genes for the major heat-shock protein of Drosophila melanogaster arranged as an inverted repeat. Nucleic Acids Res (1980) 1.67

Controlling element mediated transpositions of the white gene in Drosophila melanogaster. Genetics (1969) 1.52

Genomic organization of the 87A7 and 87Cl heat-induced loci of Drosophila melanogaster. J Mol Biol (1980) 1.52

Articles by these authors

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science (1995) 7.35

Analysis of chromatin structure by in vivo formaldehyde cross-linking. Methods (1997) 7.08

Detection in situ of genomic regulatory elements in Drosophila. Proc Natl Acad Sci U S A (1987) 7.02

A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes. Nature (1984) 6.62

Homeo boxes in the study of development. Science (1987) 6.21

P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev (1989) 5.76

Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science (1994) 5.75

Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22. Cell (1986) 5.00

A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans. Cell (1984) 4.95

The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucleic Acids Res (1987) 4.92

Control elements of the Drosophila segmentation gene fushi tarazu. Cell (1985) 4.83

An improved in situ hybridization method for the detection of cellular RNAs in Drosophila tissue sections and its application for localizing transcripts of the homeotic Antennapedia gene complex. EMBO J (1983) 4.77

Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins. Nature (1984) 4.33

The molecular basis of I-R hybrid dysgenesis in Drosophila melanogaster: identification, cloning, and properties of the I factor. Cell (1984) 4.24

The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors. Cell (1989) 4.13

Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin. Cell (1993) 4.01

Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell (1987) 3.91

Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster. EMBO J (1992) 3.87

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster. Nature (1989) 3.69

Homeotic genes and the homeobox. Annu Rev Genet (1986) 3.60

Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution. EMBO J (1990) 3.50

Structural organization and sequence of the homeotic gene Antennapedia of Drosophila melanogaster. EMBO J (1986) 3.49

Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila. EMBO J (1983) 3.47

P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila. Genes Dev (1989) 3.45

An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome. Genome Biol (2003) 3.08

Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster. Genes Dev (1992) 3.04

The interaction with DNA of wild-type and mutant fushi tarazu homeodomains. EMBO J (1990) 2.97

The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis. Cell (1998) 2.96

Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression. EMBO J (1997) 2.94

Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of Drosophila. Cell (1984) 2.89

A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants. Nucleic Acids Res (1991) 2.88

Position effects on eukaryotic gene expression. Annu Rev Cell Biol (1990) 2.82

Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia. Nature (1987) 2.81

Spatial distribution of transcripts from the segmentation gene fushi tarazu during Drosophila embryonic development. Cell (1984) 2.72

PAX-6 in development and evolution. Annu Rev Neurosci (1997) 2.68

Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts. Nature (1990) 2.67

DNA binding properties of the purified Antennapedia homeodomain. Proc Natl Acad Sci U S A (1990) 2.60

Isolation and sequence-specific DNA binding of the Antennapedia homeodomain. EMBO J (1988) 2.57

Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development (1998) 2.56

Unequal crossing-over associated with asymmetrical synapsis between nomadic elements in the Drosophila melanogaster genome. Proc Natl Acad Sci U S A (1983) 2.52

Expression of the caudal gene in the germ line of Drosophila: formation of an RNA and protein gradient during early embryogenesis. Cell (1987) 2.50

Spatial distribution of Antennapedia transcripts during Drosophila development. EMBO J (1983) 2.50

Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain. J Mol Biol (1994) 2.43

Binding of trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis. EMBO J (1998) 2.34

Selective translation of heat shock mRNA in Drosophila melanogaster depends on sequence information in the leader. EMBO J (1985) 2.30

Chromatin multiprotein complexes involved in the maintenance of transcription patterns. Curr Opin Genet Dev (1995) 2.29

Epigenetic inheritance of active chromatin after removal of the main transactivator. Science (1999) 2.28

The Drosophila sloppy paired locus encodes two proteins involved in segmentation that show homology to mammalian transcription factors. Genes Dev (1992) 2.24

Expression and function of the segmentation gene fushi tarazu during Drosophila neurogenesis. Science (1988) 2.23

Isolation of a hybrid plasmid with homologous sequences to a transposing element of Drosophila melanogaster. Cell (1980) 2.23

Regulation of Antennapedia transcript distribution by the bithorax complex in Drosophila. Nature (1984) 2.16

Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA. EMBO J (1995) 2.13

Two hybrid plasmids with D. melanogaster DNA sequences complementary to mRNA coding for the major heat shock protein. Cell (1978) 2.10

Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes. Cell (1984) 2.08

RNA binding and translational suppression by bicoid. Nature (1996) 2.08

Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster. EMBO J (1985) 2.07

Isolation of caudal, a Drosophila homeo box-containing gene with maternal expression, whose transcripts form a concentration gradient at the pre-blastoderm stage. EMBO J (1985) 2.06

twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development. Mol Cell (1999) 2.06

spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo. EMBO J (1994) 1.99

The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell (1990) 1.99

The 5S genes of Drosophila melanogaster. Cell (1977) 1.94

Direct homeodomain-DNA interaction in the autoregulation of the fushi tarazu gene. Nature (1992) 1.84

Physical map of two D. melanogaster DNA segments containing sequences coding for the 70,000 dalton heat shock protein. Cell (1979) 1.80

Chromo-domain proteins: linking chromatin structure to epigenetic regulation. Curr Opin Cell Biol (1998) 1.78

The polycomb group protein complex of Drosophila melanogaster has different compositions at different target genes. Mol Cell Biol (1997) 1.78

Cloning of the homeotic Sex combs reduced gene in Drosophila and in situ localization of its transcripts. EMBO J (1985) 1.77

Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated. Genes Dev (1990) 1.75

Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression. Development (1994) 1.74

Molecular structure and spatial expression of a homeobox gene from the labial region of the Antennapedia-complex. EMBO J (1988) 1.72

Direct interaction of the Polycomb protein with Antennapedia regulatory sequences in polytene chromosomes of Drosophila melanogaster. EMBO J (1991) 1.72

Germ line dependence of the deep orange maternal effect in Drosophila. Dev Biol (1977) 1.69

Homeodomain proteins and the regulation of gene expression. Curr Opin Cell Biol (1990) 1.65

Spatial and temporal targeting of gene expression in Drosophila by means of a tetracycline-dependent transactivator system. Development (1998) 1.62

Expression, modification, and localization of the fushi tarazu protein in Drosophila embryos. Genes Dev (1988) 1.57

Discrete Polycomb-binding sites in each parasegmental domain of the bithorax complex. Development (1995) 1.57

The homeo box: a key to the understanding of development? Cell (1985) 1.55

Cloning and transcriptional analysis of the segmentation gene fushi tarazu of Drosophila. Cell (1984) 1.55

Deletions of two heat-activated loci in Drosophila melanogaster and their effects on heat-induced protein synthesis. Cell (1977) 1.54

Developmentally regulated Drosophila gene family encoding the fork head domain. Proc Natl Acad Sci U S A (1992) 1.54

Molecular analysis of the dominant homeotic Antennapedia phenotype. EMBO J (1987) 1.53

Direct regulatory interaction of the eyeless protein with an eye-specific enhancer in the sine oculis gene during eye induction in Drosophila. Development (1999) 1.49

Determination of the three-dimensional structure of the Antennapedia homeodomain from Drosophila in solution by 1H nuclear magnetic resonance spectroscopy. J Mol Biol (1990) 1.47

The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered. Development (1996) 1.46

Fruit flies with additional expression of the elongation factor EF-1 alpha live longer. Proc Natl Acad Sci U S A (1989) 1.44

Sequence requirement for expression of the Drosophila melanogaster heat shock protein hsp22 gene during heat shock and normal development. Mol Cell Biol (1986) 1.43

New perspectives on eye evolution. Curr Opin Genet Dev (1995) 1.42

The Drosophila homeobox gene optix is capable of inducing ectopic eyes by an eyeless-independent mechanism. Development (2000) 1.40

Spreading the silence: epigenetic transcriptional regulation during Drosophila development. Dev Genet (1994) 1.40

Protein component from Drosophila larval nuclei showing sequence specificity for a short region near a major heat-shock protein gene. Cell (1981) 1.39

Functional specificity of the Antennapedia homeodomain. Proc Natl Acad Sci U S A (1993) 1.39

Excision of copia element in a revertant of the white-apricot mutation of Drosophila melanogaster leaves behind one long-terminal repeat. Mol Gen Genet (1985) 1.39

Are cross-regulatory interactions between homoeotic genes functionally significant? Nature (1990) 1.38

The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells. Proc Natl Acad Sci U S A (1991) 1.38

Developmental expression of the white locus of Drosophila melanogaster. EMBO J (1984) 1.38

Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila. Proc Natl Acad Sci U S A (1999) 1.37

Localization of the Antennapedia protein in Drosophila embryos and imaginal discs. EMBO J (1986) 1.35

P-element-mediated enhancer detection applied to the study of oogenesis in Drosophila. Development (1989) 1.34

An imprinting element from the mouse H19 locus functions as a silencer in Drosophila. Nat Genet (1997) 1.34