Published in Cell on April 07, 2006
Kinesin superfamily motor proteins and intracellular transport. Nat Rev Mol Cell Biol (2009) 5.61
The vertebrate primary cilium in development, homeostasis, and disease. Cell (2009) 5.29
Motile cilia of human airway epithelia are chemosensory. Science (2009) 4.40
The role of autophagy in mammalian development: cell makeover rather than cell death. Dev Cell (2008) 4.25
Planar cell polarity signaling: from fly development to human disease. Annu Rev Genet (2008) 3.43
Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia. Nat Cell Biol (2010) 2.68
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The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos. Nat Genet (2008) 2.31
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Planar polarization of node cells determines the rotational axis of node cilia. Nat Cell Biol (2010) 1.83
Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J Cell Biol (2008) 1.52
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Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2. Development (2011) 1.47
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Design of stable and uniform single nanoparticle photonics for in vivo dynamics imaging of nanoenvironments of zebrafish embryonic fluids. ACS Nano (2008) 1.35
Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo. Nat Commun (2012) 1.29
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Chiral blastomere arrangement dictates zygotic left-right asymmetry pathway in snails. Nature (2009) 1.26
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Chiral forces organize left-right patterning in C. elegans by uncoupling midline and anteroposterior axis. Dev Cell (2010) 1.25
FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1. Proc Natl Acad Sci U S A (2009) 1.22
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Wnt/β-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicle. Development (2011) 1.20
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy. Proc Natl Acad Sci U S A (2009) 1.19
Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome. Dis Model Mech (2010) 1.18
Reconfigurable self-assembly through chiral control of interfacial tension. Nature (2012) 1.16
Left-right determination: involvement of molecular motor KIF3, cilia, and nodal flow. Cold Spring Harb Perspect Biol (2009) 1.13
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Twisted growth and organization of cortical microtubules. J Plant Res (2006) 1.11
Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates. Development (2011) 1.10
Fish and frogs: models for vertebrate cilia signaling. Front Biosci (2008) 1.08
Rotation of organizer tissue contributes to left-right asymmetry. Anat Rec (Hoboken) (2009) 1.07
A role for the inositol kinase Ipk1 in ciliary beating and length maintenance. Proc Natl Acad Sci U S A (2007) 1.06
OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome. Hum Mol Genet (2012) 1.06
Centrosome positioning in vertebrate development. J Cell Sci (2012) 1.03
The subcellular localization of TRPP2 modulates its function. J Am Soc Nephrol (2008) 1.02
Right isomerism of the brain in inversus viscerum mutant mice. PLoS One (2008) 1.02
The emerging role of Wnt/PCP signaling in organ formation. Zebrafish (2009) 1.00
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev Dyn (2010) 1.00
Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis. Proc Natl Acad Sci U S A (2011) 0.99
Advanced cancer with situs inversus totalis associated with KIF3 complex deficiency: report of two cases. Surg Today (2010) 0.99
Preduodenal portal vein, intestinal malrotation, polysplenia, and interruption of the inferior vena cava: a review of anatomical anomalies associated with gastric cancer. Surg Radiol Anat (2011) 0.99
Zebrafish and medaka: model organisms for a comparative developmental approach of brain asymmetry. Philos Trans R Soc Lond B Biol Sci (2009) 0.98
High-speed holographic microscopy of malaria parasites reveals ambidextrous flagellar waveforms. Proc Natl Acad Sci U S A (2013) 0.98
Role of the gut endoderm in relaying left-right patterning in mice. PLoS Biol (2012) 0.97
Congenital heart disease and the specification of left-right asymmetry. Am J Physiol Heart Circ Physiol (2012) 0.94
Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. J Biol Chem (2011) 0.93
APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis. Dev Biol (2010) 0.93
Expression of two novel transcripts in the mouse definitive endoderm. Gene Expr Patterns (2010) 0.92
Mechanosignaling between central apparatus and radial spokes controls axonemal dynein activity. J Cell Biol (2014) 0.92
Intraflagellar transport: a new player at the immune synapse. Trends Immunol (2011) 0.91
Regulation of basal body and ciliary functions by Diversin. Mech Dev (2011) 0.91
Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafish. Vision Res (2012) 0.91
Reciprocal signaling between the ectoderm and a mesendodermal left-right organizer directs left-right determination in the sea urchin embryo. PLoS Genet (2012) 0.91
Diversity and convergence in the mechanisms establishing L/R asymmetry in metazoa. EMBO Rep (2014) 0.90
Broad mesodermal and endodermal deletion of Nodal at postgastrulation stages results solely in left/right axial defects. Dev Dyn (2008) 0.89
Loss of SPEF2 function in mice results in spermatogenesis defects and primary ciliary dyskinesia. Biol Reprod (2011) 0.89
Analysis of the orientation of primary cilia in growth plate cartilage: a mathematical method based on multiphoton microscopical images. J Struct Biol (2006) 0.89
Normal bias in the direction of fetal rotation depends on blastomere composition during early cleavage in the mouse. PLoS One (2010) 0.89
Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry. Development (2011) 0.88
Clinical Features and Associated Likelihood of Primary Ciliary Dyskinesia in Children and Adolescents. Ann Am Thorac Soc (2016) 0.87
Micropatterning chiral morphogenesis. Commun Integr Biol (2011) 0.87
An axonemal PP2A B-subunit is required for PP2A localization and flagellar motility. Cytoskeleton (Hoboken) (2011) 0.87
Sensory functions of motile cilia and implication for bronchiectasis. Front Biosci (Schol Ed) (2012) 0.87
Micropatterning of cells reveals chiral morphogenesis. Stem Cell Res Ther (2013) 0.87
Nodal and activin receptor-like kinase 7 induce apoptosis in human breast cancer cell lines: Role of caspase 3. Int J Physiol Pathophysiol Pharmacol (2009) 0.87
Cilia and coordination of signaling networks during heart development. Organogenesis (2013) 0.87
Measurement of fluid flow generated by artificial cilia. Biomicrofluidics (2011) 0.86
A right-sided pathway involving FGF8/Snai1 controls asymmetric development of the proepicardium in the chick embryo. Proc Natl Acad Sci U S A (2009) 0.86
Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21). Hum Mol Genet (2016) 0.85
The dynamic right-to-left translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node. PLoS One (2013) 0.85
The orphan G protein-coupled receptor 161 is required for left-right patterning. Dev Biol (2008) 0.85
Bridging structure and process in developmental biology through new imaging technologies. Dev Cell (2011) 0.85
Establishment of left-right asymmetry in vertebrate development: the node in mouse embryos. Cell Mol Life Sci (2013) 0.85
Nt mutation causing laterality defects associated with deletion of rotatin. Mamm Genome (2007) 0.85
A variant of fibroblast growth factor receptor 2 (Fgfr2) regulates left-right asymmetry in zebrafish. PLoS One (2011) 0.85
How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart disease. Mech Dev (2012) 0.85
Wnt11b is involved in cilia-mediated symmetry breakage during Xenopus left-right development. PLoS One (2013) 0.84
Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish. Dev Dyn (2010) 0.84
Sept6 is required for ciliogenesis in Kupffer's vesicle, the pronephros, and the neural tube during early embryonic development. Mol Cell Biol (2014) 0.84
Notochord Cells in Intervertebral Disc Development and Degeneration. J Dev Biol (2016) 0.84
Modelling the fluid mechanics of cilia and flagella in reproduction and development. Eur Phys J E Soft Matter (2012) 0.83
Heterotrimeric kinesin-II is necessary and sufficient to promote different stepwise assembly of morphologically distinct bipartite cilia in Drosophila antenna. Mol Biol Cell (2011) 0.83
Mapping the dynamic expression of Wnt11 and the lineage contribution of Wnt11-expressing cells during early mouse development. Dev Biol (2014) 0.82
Crosstalk of cell polarity signaling pathways. Protoplasma (2017) 0.81
Cell collectivity regulation within migrating cell cluster during Kupffer's vesicle formation in zebrafish. Front Cell Dev Biol (2015) 0.81
Kinesin superfamily motor proteins and intracellular transport. Nat Rev Mol Cell Biol (2009) 5.61
A standardized kinesin nomenclature. J Cell Biol (2004) 4.43
Analysis of the kinesin superfamily: insights into structure and function. Trends Cell Biol (2005) 3.51
FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature (2005) 3.50
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. Neuron (2010) 3.49
Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature (2002) 3.16
Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination. Cell (2005) 3.01
A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell (2004) 2.78
The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. Nat Cell Biol (2005) 2.13
Effects of extracranial-intracranial bypass for patients with hemorrhagic moyamoya disease: results of the Japan Adult Moyamoya Trial. Stroke (2014) 2.12
Efficient TALEN construction and evaluation methods for human cell and animal applications. Genes Cells (2013) 1.99
Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. Cell (2003) 1.95
KIF1A alternately uses two loops to bind microtubules. Science (2004) 1.82
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia. Nat Methods (2013) 1.76
Routine use of intravenous low-dose recombinant tissue plasminogen activator in Japanese patients: general outcomes and prognostic factors from the SAMURAI register. Stroke (2009) 1.63
Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm. Blood (2011) 1.61
Prediction of coronary artery disease in patients undergoing carotid endarterectomy. J Neurosurg (2005) 1.55
Intracranial hemorrhage during dabigatran treatment. Circ J (2014) 1.54
Blood pressure changes during the initial week after different subtypes of ischemic stroke. Stroke (2006) 1.50
KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD. Nat Cell Biol (2008) 1.49
Recurrent small-artery disease in hyperhomocysteinemia: widowers' stroke syndrome? Intern Med (2004) 1.47
Prospective cohort study of gastrointestinal complications and vascular diseases in patients taking aspirin: rationale and design of the MAGIC Study. Cardiovasc Drugs Ther (2011) 1.46
Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport. J Cell Biol (2011) 1.41
Efficient identification of TALEN-mediated genome modifications using heteroduplex mobility assays. Genes Cells (2013) 1.41
Relative systolic blood pressure reduction and clinical outcomes in hyperacute intracerebral hemorrhage: the SAMURAI-ICH observational study. J Hypertens (2015) 1.40
Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin. Nat Struct Mol Biol (2008) 1.29
Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation. Immunity (2004) 1.22
Quantitative assay for TALEN activity at endogenous genomic loci. Biol Open (2013) 1.22
KIF16B/Rab14 molecular motor complex is critical for early embryonic development by transporting FGF receptor. Dev Cell (2011) 1.19
Influence of interleukin-12 receptor beta1 polymorphisms on tuberculosis. Hum Genet (2002) 1.18
The mechanisms of kinesin motor motility: lessons from the monomeric motor KIF1A. Nat Rev Mol Cell Biol (2009) 1.16
Free radical scavenger, edaravone, in stroke with internal carotid artery occlusion. J Neurol Sci (2004) 1.14
Left-right determination: involvement of molecular motor KIF3, cilia, and nodal flow. Cold Spring Harb Perspect Biol (2009) 1.13
Reduced estimated glomerular filtration rate is associated with stroke outcome after intravenous rt-PA: the Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement (SAMURAI) rt-PA registry. Cerebrovasc Dis (2010) 1.11
Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes. Am J Med Genet A (2006) 1.08
The effect of weekends and holidays on stroke outcome in acute stroke units. Cerebrovasc Dis (2005) 1.08
Morphological classification of mobile plaques and their association with early recurrence of stroke. Cerebrovasc Dis (2010) 1.07
Analysis of renal cell carcinoma as a first step for developing mass spectrometry-based diagnostics. J Am Soc Mass Spectrom (2012) 1.04
Intracellular transport of single-headed molecular motors KIF1A. Phys Rev Lett (2005) 1.02
Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy. J Cell Biol (2012) 0.98
Hospital cost of ischemic stroke and intracerebral hemorrhage in Japanese stroke centers. Health Policy (2004) 0.98
Ambient imaging mass spectrometry by electrospray ionization using solid needle as sampling probe. J Mass Spectrom (2009) 0.97
Multiple primary cilia modulate the fluid transcytosis in choroid plexus epithelium. Traffic (2009) 0.97
Endothelialization and altered hematopoiesis by persistent Etv2 expression in mice. Exp Hematol (2012) 0.97
Role of KIFC3 motor protein in Golgi positioning and integration. J Cell Biol (2002) 0.95
Risk factor profile and management of cerebrovascular patients in the REACH Registry. Cerebrovasc Dis (2008) 0.95
The clinical features of adult unilateral moyamoya disease: does it have the same clinical characteristics as typical moyamoya disease? Cerebrovasc Dis (2008) 0.94
Nodal cilia dynamics and the specification of the left/right axis in early vertebrate embryo development. Biophys J (2005) 0.94
Cilia, KIF3 molecular motor and nodal flow. Curr Opin Cell Biol (2012) 0.94
Deep venous thrombosis after acute intracerebral hemorrhage. J Neurol Sci (2008) 0.93
Genetically encoded system to track histone modification in vivo. Sci Rep (2013) 0.93
Impact of early blood pressure variability on stroke outcomes after thrombolysis: the SAMURAI rt-PA Registry. Stroke (2013) 0.92
Lack of association between infectious burden and carotid atherosclerosis in Japanese patients. J Stroke Cerebrovasc Dis (2007) 0.91
Predisposing factors for acute deterioration of minor ischemic stroke. J Neurol Sci (2009) 0.90
The life-threatening complication of a vascular graft rupture early after a thoracic aortic replacement. Eur J Cardiothorac Surg (2012) 0.90
Large-caliber persistent sciatic artery with aneurysm. Anat Sci Int (2008) 0.90
Risk score for predicting recurrence in patients with ischemic stroke: the Fukuoka stroke risk score for Japanese. Cerebrovasc Dis (2012) 0.89
Thrombolysis with 0.6 mg/kg intravenous alteplase for acute ischemic stroke in routine clinical practice: the Japan post-Marketing Alteplase Registration Study (J-MARS). Stroke (2010) 0.89
Characteristics of probe electrospray generated from a solid needle. J Phys Chem B (2008) 0.89
ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short- and long-term risks of stroke after transient ischemic attack. Stroke (2013) 0.89
Risk factor profiles, drug usage, and prevalence of aspirin-associated gastroduodenal injuries among high-risk cardiovascular Japanese patients: the results from the MAGIC study. J Gastroenterol (2013) 0.89
Extensive bihemispheric ischemia caused by acute occlusion of three major arteries to the brain. J Neurol Sci (2003) 0.88
Angiographic characteristics of radiation-induced carotid arterial stenosis. Angiology (2009) 0.88
Signaling through the primary cilium affects glial cell survival under a stressed environment. Glia (2011) 0.88
MPO-ANCA-positive Wegener's granulomatosis presenting with hypertrophic cranial pachymeningitis: case report and review of the literature. Mod Rheumatol (2004) 0.87
Aromatase-knockout mouse carrying an estrogen-inducible enhanced green fluorescent protein gene facilitates detection of estrogen actions in vivo. Endocrinology (2003) 0.87
Babinski-Nageotte syndrome due to vertebral artery dissection. Intern Med (2003) 0.87
Evaluation of distal extracranial internal carotid artery by transoral carotid ultrasonography in patients with severe carotid stenosis. AJNR Am J Neuroradiol (2002) 0.86
Diagnostic impact of transcranial color-coded real-time sonography with echo contrast agents for hyperperfusion syndrome after carotid endarterectomy. Stroke (2004) 0.86
The impact of hyperacute blood pressure lowering on the early clinical outcome following intracerebral hemorrhage. J Hypertens (2008) 0.86
Carotid artery calcification at the initiation of hemodialysis is a risk factor for cardiovascular events in patients with end-stage renal disease: a cohort study. BMC Nephrol (2011) 0.86
Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study. BMC Neurol (2013) 0.86
Antegrade internal carotid artery collateral flow and cerebral blood flow in patients with common carotid artery occlusion. J Ultrasound Med (2012) 0.86
Acute blood pressure levels and neurological deterioration in different subtypes of ischemic stroke. Stroke (2009) 0.85
[A case of the spontaneous dissection of the bilateral internal carotid arteries diagnosed by the transoral carotid ultrasonography (TOCU)]. Rinsho Shinkeigaku (2007) 0.85
Proteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammals. Biol Open (2012) 0.85
Incidence and predictors of ischemic stroke events during hospitalization in patients with transient ischemic attack. Cerebrovasc Dis (2014) 0.85
PDGF receptor alpha+ mesoderm contributes to endothelial and hematopoietic cells in mice. Dev Dyn (2013) 0.84
Carotid artery calcification on multislice detector-row computed tomography. Cerebrovasc Dis (2007) 0.84
Hedgehog signaling regulates myelination in the peripheral nervous system through primary cilia. Differentiation (2011) 0.84
Successful high dose glucocorticoid treatment for subacute neuromyelitis optica with systemic lupus erythematosus. Intern Med (2005) 0.84
Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport. Mol Cell Biol (2002) 0.84
Real-time diagnosis of chemically induced hepatocellular carcinoma using a novel mass spectrometry-based technique. Anal Biochem (2013) 0.84
Polymorphisms in the lymphotoxin alpha gene and the risk of ischemic stroke in the Japanese population. The Fukuoka Stroke Registry and the Hisayama Study. Cerebrovasc Dis (2008) 0.84
Real-time analysis of living animals by electrospray ionization mass spectrometry. Anal Biochem (2011) 0.84
Transoral carotid ultrasonography as a diagnostic aid in patients with severe carotid stenosis. Cerebrovasc Dis (2003) 0.83
Biomolecular analysis and cancer diagnostics by negative mode probe electrospray ionization. Analyst (2013) 0.83
Differences in diffusion-weighted image and transesophageal echocardiographical findings in cardiogenic, paradoxical and aortogenic brain embolism. Cerebrovasc Dis (2011) 0.83
Effects of carotid endarterectomy on cerebral blood flow and neuropsychological test performance in patients with high-grade carotid stenosis. J Neurol Sci (2003) 0.83
Therapeutic time window for YAG laser-induced reperfusion of thrombotic stroke in hypertensive rats. Neuroreport (2002) 0.83
Radiological imaging features of invasive micropapillary carcinoma of the breast and axillary lymph nodes. Oncol Rep (2008) 0.82
Utility of initial MRI for predicting extent of residual disease after neoadjuvant chemotherapy: analysis of 70 breast cancer patients. Oncol Rep (2004) 0.82
Application of probe electrospray to direct ambient analysis of biological samples. Rapid Commun Mass Spectrom (2008) 0.82