Published in Proc Natl Acad Sci U S A on September 21, 2011
The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell (2013) 3.27
LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis. Cell Death Dis (2014) 1.37
The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells. Nucleic Acids Res (2014) 1.16
Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle. J Biol Chem (2013) 1.11
The H19 Long non-coding RNA in cancer initiation, progression and metastasis - a proposed unifying theory. Mol Cancer (2015) 1.08
The increasing complexity of the oncofetal h19 gene locus: functional dissection and therapeutic intervention. Int J Mol Sci (2013) 1.03
Histone h1.3 suppresses h19 noncoding RNA expression and cell growth of ovarian cancer cells. Cancer Res (2014) 1.00
The human imprintome: regulatory mechanisms, methods of ascertainment, and roles in disease susceptibility. ILAR J (2012) 0.99
H19 antisense RNA can up-regulate Igf2 transcription by activation of a novel promoter in mouse myoblasts. PLoS One (2012) 0.98
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells. Proc Natl Acad Sci U S A (2012) 0.96
An emerging role for long non-coding RNAs in cancer metastasis. Front Genet (2014) 0.95
Genome-wide DNA methylation studies suggest distinct DNA methylation patterns in pediatric embryonal and alveolar rhabdomyosarcomas. Epigenetics (2012) 0.93
H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase. Nat Commun (2015) 0.91
Long noncoding RNAs, emerging players in muscle differentiation and disease. Skelet Muscle (2014) 0.90
The short and long of noncoding sequences in the control of vascular cell phenotypes. Cell Mol Life Sci (2015) 0.88
Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. Sarcoma (2015) 0.85
Could lncRNAs be the missing links in control of mesenchymal stem cell differentiation? J Cell Physiol (2015) 0.85
Genetics of pediatric renal tumors. Pediatr Nephrol (2012) 0.85
The role of long non-coding RNAs in genome formatting and expression. Front Genet (2015) 0.83
Stem cell activation in skeletal muscle regeneration. Cell Mol Life Sci (2015) 0.83
H19 Long Noncoding RNA Regulates Intestinal Epithelial Barrier Function via MicroRNA 675 by Interacting with RNA-Binding Protein HuR. Mol Cell Biol (2016) 0.83
Long Non-Coding RNAs Embedded in the Rb and p53 Pathways. Cancers (Basel) (2013) 0.80
The enigmatic ERH protein: its role in cell cycle, RNA splicing and cancer. Protein Cell (2013) 0.80
Functions and mechanisms of long noncoding RNAs in lung cancer. Onco Targets Ther (2016) 0.79
Noncoding RNAs in the regulation of skeletal muscle biology in health and disease. J Mol Med (Berl) (2016) 0.78
Identification of amino acid residues of ERH required for its recruitment to nuclear speckles and replication foci in HeLa cells. PLoS One (2013) 0.77
An information theoretic method to identify combinations of genomic alterations that promote glioblastoma. J Mol Cell Biol (2015) 0.76
Tumour suppressors: HOTS makes antisense. Nat Rev Cancer (2011) 0.75
Targeting H19, an Imprinted Long Non-Coding RNA, in Hepatic Functions and Liver Diseases. Diseases (2017) 0.75
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature (2010) 23.55
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature (2000) 14.91
The history of cancer epigenetics. Nat Rev Cancer (2004) 14.38
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature (2000) 12.97
Tsix, a gene antisense to Xist at the X-inactivation centre. Nat Genet (1999) 6.77
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev (1998) 6.29
Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature (1995) 6.18
Relaxation of imprinted genes in human cancer. Nature (1993) 3.86
A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development. Mol Cell Biol (1997) 3.51
Microdeletions in the human H19 DMR result in loss of IGF2 imprinting and Beckwith-Wiedemann syndrome. Nat Genet (2004) 3.32
Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting. Proc Natl Acad Sci U S A (1999) 3.22
Tumour-suppressor activity of H19 RNA. Nature (1993) 3.06
The imprinted H19 noncoding RNA is a primary microRNA precursor. RNA (2007) 2.91
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis (2009) 2.45
Human lineage-specific amplification, selection, and neuronal expression of DUF1220 domains. Science (2006) 2.18
The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1. Nat Genet (2000) 2.16
A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting. Proc Natl Acad Sci U S A (1989) 2.02
NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas. Proc Natl Acad Sci U S A (1999) 2.00
Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element. Genes Dev (1997) 1.97
SKAR is a specific target of S6 kinase 1 in cell growth control. Curr Biol (2004) 1.90
Tumor development in the Beckwith-Wiedemann syndrome is associated with a variety of constitutional molecular 11p15 alterations including imprinting defects of KCNQ1OT1. Hum Mol Genet (2001) 1.58
Igf2 imprinting does not require its own DNA methylation or H19 RNA. Genes Dev (1998) 1.55
A novel H19 antisense RNA overexpressed in breast cancer contributes to paternal IGF2 expression. Mol Cell Biol (2008) 1.50
H19 and Igf2--enhancing the confusion? Trends Genet (2003) 1.42
POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer. Proc Natl Acad Sci U S A (2002) 1.25
Evidence for evolutionarily conserved secondary structure in the H19 tumor suppressor RNA. Nucleic Acids Res (2000) 1.20
Ciz1 promotes mammalian DNA replication. J Cell Sci (2004) 1.17
Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting. Hum Mol Genet (1999) 1.08
H19 expression and tumorigenicity of choriocarcinoma derived cell lines. Oncogene (1995) 0.89
A 1.55 A resolution X-ray crystal structure of HEF2/ERH and insights into its transcriptional and cell-cycle interaction networks. Proteins (2007) 0.88
Loss of heterozygosity at chromosome 11p15 in Wilms tumors: identification of two independent regions. Oncogene (1998) 0.86
p57K1P2 is expressed in Wilms' tumor with LOH of 11p15.5. Genes Chromosomes Cancer (1996) 0.85
Wilms' tumor as a model for cancer biology. Methods Mol Biol (2003) 0.79
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature (2002) 9.40
Increased methylation variation in epigenetic domains across cancer types. Nat Genet (2011) 8.92
Comprehensive high-throughput arrays for relative methylation (CHARM). Genome Res (2008) 8.62
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature (2008) 7.64
Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science (2003) 6.85
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature (2010) 6.06
Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays. Bioinformatics (2014) 5.93
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol (2013) 5.89
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet (2009) 5.52
An integrated epigenetic and genetic approach to common human disease. Trends Genet (2004) 4.89
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci U S A (2002) 4.27
An X chromosome gene, WTX, is commonly inactivated in Wilms tumor. Science (2007) 4.00
Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19. Am J Hum Genet (2002) 3.93
Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies. Int J Epidemiol (2012) 3.62
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation. Nat Genet (2004) 3.56
A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes. Genome Res (2002) 3.50
DNA methylation signatures within the human brain. Am J Hum Genet (2007) 3.50
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol (2011) 3.25
Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res (2002) 3.21
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition. Nat Struct Mol Biol (2011) 3.00
Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects. Am J Hum Genet (2002) 2.73
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. Cancer Cell (2004) 2.73
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science (2005) 2.72
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. Proc Natl Acad Sci U S A (2002) 2.62
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity. Cancer Res (2002) 2.52
Reversible switching between epigenetic states in honeybee behavioral subcastes. Nat Neurosci (2012) 2.44
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer (2013) 2.41
Epigenetics and assisted reproductive technology: a call for investigation. Am J Hum Genet (2004) 2.41
SNP-specific array-based allele-specific expression analysis. Genome Res (2008) 2.30
The emerging science of epigenomics. Hum Mol Genet (2006) 2.22
Accurate genome-scale percentage DNA methylation estimates from microarray data. Biostatistics (2010) 2.11
Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology (2004) 2.06
Redefining CpG islands using hidden Markov models. Biostatistics (2010) 2.03
Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients. Fertil Steril (2005) 1.87
Regulated noise in the epigenetic landscape of development and disease. Cell (2012) 1.79
Significance analysis and statistical dissection of variably methylated regions. Biostatistics (2011) 1.74
Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells. Mol Cancer Ther (2007) 1.42
Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk. Cancer Res (2005) 1.39
Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome. Am J Hum Genet (2004) 1.38
A species-generalized probabilistic model-based definition of CpG islands. Mamm Genome (2009) 1.36
Large-scale hypomethylated blocks associated with Epstein-Barr virus-induced B-cell immortalization. Genome Res (2013) 1.34
DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth. Int J Epidemiol (2012) 1.30
Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors. J Natl Cancer Inst (2007) 1.29
BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression. Mol Cell Biol (2008) 1.26
Measuring cell-type specific differential methylation in human brain tissue. Genome Biol (2013) 1.19
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. Cancer Res (2008) 1.17
Genome-wide DNA methylation scan in major depressive disorder. PLoS One (2012) 1.17
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk. Proc Natl Acad Sci U S A (2007) 1.15
Higher order chromatin organization in cancer. Semin Cancer Biol (2012) 1.09
Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification. Genome Res (2008) 1.06
Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages. Proc Natl Acad Sci U S A (2002) 1.05
Comprehensive high-throughput arrays for relative methylation (CHARM). Curr Protoc Hum Genet (2010) 1.02
Genetics and epigenetics--nature's pen-and-pencil set. N Engl J Med (2007) 1.02
CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region. Cancer Res (2008) 0.99
The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells. J Cell Biochem (2007) 0.97
Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions. BMC Genomics (2012) 0.94
Children with idiopathic hemihypertrophy and beckwith-wiedemann syndrome have different constitutional epigenotypes associated with wilms tumor. Am J Hum Genet (2005) 0.93
A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol (2014) 0.92
Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene. Epigenetics (2009) 0.91
Factors associated with preterm delivery in mothers of children with Beckwith-Wiedemann syndrome: a case cohort study from the BWS registry. Am J Med Genet A (2005) 0.90
A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction. Cell Cycle (2009) 0.87
Adaptation of the CHARM DNA methylation platform for the rat genome reveals novel brain region-specific differences. Epigenetics (2011) 0.84
Association of chromosome arm 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor. Genes Chromosomes Cancer (2005) 0.82
Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1. Am J Med Genet B Neuropsychiatr Genet (2008) 0.82
Addition of H19 'loss of methylation testing' for Beckwith-Wiedemann syndrome (BWS) increases the diagnostic yield. J Mol Diagn (2010) 0.82
Epigenetic variability and the evolution of human cancer. Adv Cancer Res (2003) 0.80
Inheritance pattern of Beckwith-Wiedemann syndrome is heterogeneous in 291 families with an affected proband. Am J Med Genet A (2005) 0.75
Stem cell differentiation as a renewal-reward process: predictions and validation in the colonic crypt. Adv Exp Med Biol (2012) 0.75
Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors. Cancer Genet Cytogenet (2003) 0.75