Published in Proc Natl Acad Sci U S A on February 23, 2004
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell (2010) 17.87
AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res (2006) 6.22
Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell (2007) 5.29
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J (2004) 4.45
HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev (2009) 4.41
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability. Mol Cell (2011) 4.29
Diverse molecular functions of Hu proteins. Cell Mol Life Sci (2008) 4.09
Influence of RNA secondary structure on the pre-mRNA splicing process. Mol Cell Biol (2004) 3.07
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. Mol Cell Biol (2005) 2.83
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci U S A (2008) 2.76
Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip Rev RNA (2010) 2.59
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha. EMBO J (2005) 2.33
miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. Proc Natl Acad Sci U S A (2008) 2.29
MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90. Mol Cell Biol (2008) 2.26
Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs. Mol Cell Biol (2007) 2.24
PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins. J Vis Exp (2010) 2.23
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Mol Cell Biol (2007) 2.20
Post-transcriptional gene regulation: from genome-wide studies to principles. Cell Mol Life Sci (2008) 2.18
Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev (2008) 2.14
Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets. Mol Cell Biol (2008) 2.04
Derepression of the Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cells. Genes Dev (2006) 2.02
Regulated protein aggregation: stress granules and neurodegeneration. Mol Neurodegener (2012) 1.95
Translational repression by RNA-binding protein TIAR. Mol Cell Biol (2006) 1.87
Predicting in vivo binding sites of RNA-binding proteins using mRNA secondary structure. RNA (2010) 1.87
HuR function in disease. Front Biosci (Landmark Ed) (2012) 1.86
Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines. Nucleic Acids Res (2009) 1.86
RNAcontext: a new method for learning the sequence and structure binding preferences of RNA-binding proteins. PLoS Comput Biol (2010) 1.78
Functional interplay between RNA-binding protein HuR and microRNAs. Curr Protein Pept Sci (2012) 1.71
Cis-acting determinants of asymmetric, cytoplasmic RNA transport. RNA (2007) 1.60
Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements. Cell Mol Life Sci (2010) 1.58
RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript. Genes Dev (2006) 1.58
NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif. Nucleic Acids Res (2009) 1.50
Global analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stability. Mol Cell Biol (2005) 1.50
Sirtuin 1 regulation of developmental genes during differentiation of stem cells. Proc Natl Acad Sci U S A (2010) 1.48
The regulation of mRNA stability in mammalian cells: 2.0. Gene (2012) 1.46
Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR. Mol Cell Biol (2007) 1.44
The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase. Cancer Res (2009) 1.41
Coordinated posttranscriptional mRNA population dynamics during T-cell activation. Mol Syst Biol (2009) 1.40
Phosphorylated HuR shuttles in cycles. Cell Cycle (2008) 1.38
Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation. Mol Biol Cell (2009) 1.38
HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay. Mol Cell Biol (2010) 1.35
Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation. Nucleic Acids Res (2009) 1.35
Global coordination of transcriptional control and mRNA decay during cellular differentiation. Mol Syst Biol (2010) 1.34
RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability. Nucleic Acids Res (2010) 1.34
Minireview: global regulation and dynamics of ribonucleic Acid. Endocrinology (2010) 1.31
Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis. Int J Mol Sci (2013) 1.28
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest (2008) 1.28
Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells. Mol Biol Cell (2007) 1.28
Competitive regulation of nucleolin expression by HuR and miR-494. Mol Cell Biol (2011) 1.28
Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron (2012) 1.27
RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage. Nucleic Acids Res (2011) 1.27
Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets. Nucleic Acids Res (2009) 1.26
Unbiased RNA-protein interaction screen by quantitative proteomics. Proc Natl Acad Sci U S A (2009) 1.26
Translational control of TOP2A influences doxorubicin efficacy. Mol Cell Biol (2011) 1.25
Identification of a signature motif in target mRNAs of RNA-binding protein AUF1. Nucleic Acids Res (2008) 1.25
Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites. J Biol Chem (2011) 1.24
Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation. EMBO J (2011) 1.21
Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs. Nucleic Acids Res (2011) 1.21
Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1. J Biol Chem (2010) 1.20
Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation. Aging (Albany NY) (2009) 1.20
Modification at HuR(S242) alters HuR localization and proliferative influence. Cell Cycle (2008) 1.20
TERRA transcripts are bound by a complex array of RNA-binding proteins. Nat Commun (2010) 1.19
Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3' untranslated region to HuR and AUF1. Mol Cell Biol (2010) 1.17
RNA-binding proteins implicated in the hypoxic response. J Cell Mol Med (2009) 1.15
A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics. J Biol Chem (2005) 1.14
Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression. Brief Funct Genomics (2010) 1.14
Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR. J Biol Chem (2005) 1.12
Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6. Mol Cancer Res (2008) 1.11
Mechanisms coordinating ELAV/Hu mRNA regulons. Curr Opin Genet Dev (2013) 1.10
The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer. BMC Cancer (2010) 1.10
Different modes of interaction by TIAR and HuR with target RNA and DNA. Nucleic Acids Res (2011) 1.10
Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium. J Immunol (2011) 1.09
Posttranscriptional regulation of IL-13 in T cells: role of the RNA-binding protein HuR. J Allergy Clin Immunol (2008) 1.08
Regulation of HuR by DNA Damage Response Kinases. J Nucleic Acids (2010) 1.06
Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1. Front Biosci (Landmark Ed) (2011) 1.06
Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs. Front Mol Neurosci (2011) 1.06
Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer. Mol Cell Biol (2008) 1.06
HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells. Cancer Res (2014) 1.05
ELAV multimerizes on conserved AU4-6 motifs important for ewg splicing regulation. Mol Cell Biol (2005) 1.04
The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets. Nucleic Acids Res (2008) 1.04
Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity. Nucleic Acids Res (2013) 1.04
The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells. Mol Cancer Res (2012) 1.02
Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function. Nucleic Acids Res (2011) 1.02
The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex. Hum Genet (2008) 1.00
Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress. J Biol Chem (2011) 1.00
Finding the target sites of RNA-binding proteins. Wiley Interdiscip Rev RNA (2013) 0.99
Post-transcriptional RNA regulons affecting cell cycle and proliferation. Semin Cell Dev Biol (2014) 0.99
Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells. Mol Cancer (2012) 0.98
Metabolic engineering in the -omics era: elucidating and modulating regulatory networks. Microbiol Mol Biol Rev (2005) 0.97
Perspectives on the ARE as it turns 25 years old. Wiley Interdiscip Rev RNA (2012) 0.97
The human glucocorticoid receptor as an RNA-binding protein: global analysis of glucocorticoid receptor-associated transcripts and identification of a target RNA motif. J Immunol (2010) 0.97
HuR interacts with human immunodeficiency virus type 1 reverse transcriptase, and modulates reverse transcription in infected cells. Retrovirology (2008) 0.96
RNA-binding protein AUF1 represses Dicer expression. Nucleic Acids Res (2012) 0.96
Expression and distribution of HuR during ATP depletion and recovery in proximal tubule cells. Am J Physiol Renal Physiol (2006) 0.95
HuR stabilizes vacuolar H+-translocating ATPase mRNA during cellular energy depletion. J Biol Chem (2005) 0.95
β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells. Nucleic Acids Res (2012) 0.94
The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA. Nucleic Acids Res (2009) 0.94
Dynamics of native β-actin mRNA transport in the cytoplasm. Traffic (2011) 0.94
Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis. J Biol Chem (2012) 0.94
Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89
AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem Sci (1995) 14.81
RNA sequence analysis using covariance models. Nucleic Acids Res (1994) 14.60
HuR and mRNA stability. Cell Mol Life Sci (2001) 8.06
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J (1998) 7.62
Analysis of microarray data using Z score transformation. J Mol Diagn (2003) 6.82
Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem (1996) 5.82
HuR regulates p21 mRNA stabilization by UV light. Mol Cell Biol (2000) 4.96
Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs. Mol Cell Biol (1993) 4.63
Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR. J Biol Chem (1998) 4.57
Eukaryotic mRNPs may represent posttranscriptional operons. Mol Cell (2002) 4.39
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc Natl Acad Sci U S A (2003) 4.34
HuR binding to cytoplasmic mRNA is perturbed by heat shock. Proc Natl Acad Sci U S A (2000) 4.14
HNS, a nuclear-cytoplasmic shuttling sequence in HuR. Proc Natl Acad Sci U S A (1998) 4.14
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. EMBO J (2000) 4.11
Finding the most significant common sequence and structure motifs in a set of RNA sequences. Nucleic Acids Res (1997) 4.04
Ribonomics: identifying mRNA subsets in mRNP complexes using antibodies to RNA-binding proteins and genomic arrays. Methods (2002) 3.92
Global analysis of stress-regulated mRNA turnover by using cDNA arrays. Proc Natl Acad Sci U S A (2002) 3.71
ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR. Genes Dev (2002) 3.71
Why is Hu where? Shuttling of early-response-gene messenger RNA subsets. Proc Natl Acad Sci U S A (1999) 3.61
A conserved family of elav-like genes in vertebrates. Proc Natl Acad Sci U S A (1995) 3.43
Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. Mol Cell Biol (1997) 3.21
Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression. Am J Hum Genet (1997) 3.05
Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1. Proc Natl Acad Sci U S A (1994) 2.95
Delineation of mRNA export pathways by the use of cell-permeable peptides. Science (2001) 2.87
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J Cell Sci (1998) 2.83
Role of the RNA-binding protein HuR in colon carcinogenesis. Oncogene (2003) 2.69
ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells. Genes Dev (1999) 2.65
Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer--a quantitative western blot analysis. Ann Neurol (1990) 2.58
HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs. Cancer Res (2001) 2.29
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence. Mol Cell Biol (2001) 2.15
AMP-activated kinase regulates cytoplasmic HuR. Mol Cell Biol (2002) 2.14
Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor. J Neurosci (1994) 2.09
Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization. Mol Cell Biol (2002) 2.08
A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA. Mol Cell Biol (2000) 2.08
The Elav-like proteins bind to a conserved regulatory element in the 3'-untranslated region of GAP-43 mRNA. J Biol Chem (1997) 2.07
Application of cDNA microarrays to examine gene expression differences in schizophrenia. Brain Res Bull (2001) 1.97
Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol (2003) 1.93
Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells. Mol Cell Biol (2003) 1.83
Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR. J Immunol (2003) 1.57
RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation. J Biol Chem (2003) 1.51
The proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein U. J Biol Chem (2003) 1.50
Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissue. Mol Carcinog (2000) 1.45
von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays. Mol Cell Biol (2003) 1.37
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science (2004) 11.39
Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell (2007) 5.29
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell (2009) 5.22
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J (2004) 4.45
HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev (2009) 4.41
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc Natl Acad Sci U S A (2003) 4.34
LincRNA-p21 suppresses target mRNA translation. Mol Cell (2012) 3.87
Desperately seeking microRNA targets. Nat Struct Mol Biol (2010) 3.85
Global analysis of stress-regulated mRNA turnover by using cDNA arrays. Proc Natl Acad Sci U S A (2002) 3.71
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell (2010) 3.27
AGEMAP: a gene expression database for aging in mice. PLoS Genet (2007) 3.22
p16(INK4a) translation suppressed by miR-24. PLoS One (2008) 3.08
miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One (2009) 2.97
MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res (2010) 2.83
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. Mol Cell Biol (2005) 2.83
Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biol Psychiatry (2005) 2.79
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci U S A (2008) 2.76
Role of the RNA-binding protein HuR in colon carcinogenesis. Oncogene (2003) 2.69
Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. J Biol Chem (2006) 2.67
miR-519 suppresses tumor growth by reducing HuR levels. Cell Cycle (2010) 2.63
Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem (2008) 2.60
Posttranscriptional regulation of cancer traits by HuR. Wiley Interdiscip Rev RNA (2010) 2.59
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet (2013) 2.59
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function. J Clin Invest (2013) 2.50
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling. J Biol Chem (2003) 2.38
HuR: post-transcriptional paths to malignancy. RNA Biol (2005) 2.38
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha. EMBO J (2005) 2.33
miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. Proc Natl Acad Sci U S A (2008) 2.29
MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90. Mol Cell Biol (2008) 2.26
Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle (2007) 2.25
Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs. Mol Cell Biol (2007) 2.24
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Mol Cell Biol (2007) 2.20
Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability. BMC Genomics (2005) 2.18
Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev (2008) 2.14
AMP-activated kinase regulates cytoplasmic HuR. Mol Cell Biol (2002) 2.14
GU-rich RNA: expanding CUGBP1 function, broadening mRNA turnover. Mol Cell (2008) 2.08
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. Mol Cell Biol (2006) 2.05
Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron (2004) 1.99
Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs. Sci Signal (2009) 1.97
Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function. J Biol Chem (2003) 1.95
Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol (2003) 1.93
microRNA expression patterns reveal differential expression of target genes with age. PLoS One (2010) 1.92
A genome-wide association study identifies two new risk loci for Graves' disease. Nat Genet (2011) 1.92
Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene. Cell Host Microbe (2009) 1.90
The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis. Cancer Res (2009) 1.88
Translational repression by RNA-binding protein TIAR. Mol Cell Biol (2006) 1.87
Posttranscriptional gene regulation by long noncoding RNA. J Mol Biol (2012) 1.87
Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J (2009) 1.87
HuR function in disease. Front Biosci (Landmark Ed) (2012) 1.86
Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines. Nucleic Acids Res (2009) 1.86
Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells. Mol Cell Biol (2003) 1.83
SRT1720 improves survival and healthspan of obese mice. Sci Rep (2011) 1.81
miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2010) 1.75
Functional interplay between RNA-binding protein HuR and microRNAs. Curr Protein Pept Sci (2012) 1.71
Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs. J Biol Chem (2006) 1.69
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination. Nat Commun (2013) 1.62
hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies. Nat Struct Mol Biol (2010) 1.61
Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines. BMC Dev Biol (2006) 1.58
Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR. J Immunol (2003) 1.57
Differential dependency network analysis to identify condition-specific topological changes in biological networks. Bioinformatics (2008) 1.56
Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. PLoS Genet (2011) 1.55
MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence. Aging (Albany NY) (2010) 1.53
Graphene quantum dots: emergent nanolights for bioimaging, sensors, catalysis and photovoltaic devices. Chem Commun (Camb) (2012) 1.53
Ubiquitin-mediated proteolysis of HuR by heat shock. EMBO J (2009) 1.52
Posttranscriptional derepression of GADD45alpha by genotoxic stress. Mol Cell (2006) 1.50
NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif. Nucleic Acids Res (2009) 1.50