Published in Antiviral Res on December 01, 2010
Antiviral agents and HIV prevention: controversies, conflicts, and consensus. AIDS (2012) 1.73
Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring. Antimicrob Agents Chemother (2011) 1.38
Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection. J Antimicrob Chemother (2012) 1.34
Microbicides: topical prevention against HIV. Cold Spring Harb Perspect Med (2012) 1.31
An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaques. Sci Transl Med (2012) 1.23
An intravaginal ring for the simultaneous delivery of multiple drugs. J Pharm Sci (2012) 1.17
Preventing mucosal HIV transmission with topical microbicides: challenges and opportunities. Antiviral Res (2010) 1.15
Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques. J Antimicrob Chemother (2012) 1.14
Safety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques. Antimicrob Agents Chemother (2012) 1.11
Tenofovir and tenofovir disoproxil fumarate pharmacokinetics from intravaginal rings. AIDS (2012) 1.10
Drug-eluting fibers for HIV-1 inhibition and contraception. PLoS One (2012) 1.08
Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc. J Control Release (2011) 1.05
Clinical evaluation of microbicide formulations. Antiviral Res (2010) 1.05
The nonnucleoside reverse transcription inhibitor MIV-160 delivered from an intravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT Infection. AIDS Res Hum Retroviruses (2012) 1.04
Vaginal rings for delivery of HIV microbicides. Int J Womens Health (2012) 1.04
Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission. Proc Natl Acad Sci U S A (2012) 1.03
The Promise of Antiretrovirals for HIV Prevention. Curr Infect Dis Rep (2012) 1.02
Formulation, pharmacokinetics and pharmacodynamics of topical microbicides. Best Pract Res Clin Obstet Gynaecol (2012) 1.01
Pharmacokinetics of a multipurpose pod-intravaginal ring simultaneously delivering five drugs in an ovine model. Antimicrob Agents Chemother (2013) 0.97
HIV transmission: time for translational studies to bridge the gap. Sci Transl Med (2011) 0.97
Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220. J Antimicrob Chemother (2012) 0.95
Combinations of griffithsin with other carbohydrate-binding agents demonstrate superior activity against HIV Type 1, HIV Type 2, and selected carbohydrate-binding agent-resistant HIV Type 1 strains. AIDS Res Hum Retroviruses (2012) 0.93
Pharmacokinetics and preliminary safety study of pod-intravaginal rings delivering antiretroviral combinations for HIV prophylaxis in a macaque model. Antimicrob Agents Chemother (2014) 0.93
Safety and pharmacokinetics of aciclovir in women following release from a silicone elastomer vaginal ring. J Antimicrob Chemother (2012) 0.91
An intravaginal ring for the sustained delivery of antibodies. J Pharm Sci (2014) 0.90
Microbicides for HIV prevention. Indian J Med Res (2011) 0.90
The ring plus project: safety and acceptability of vaginal rings that protect women from unintended pregnancy. BMC Public Health (2015) 0.86
A temperature-monitoring vaginal ring for measuring adherence. PLoS One (2015) 0.86
An intravaginal ring for the sustained delivery of tenofovir disoproxil fumarate. Int J Pharm (2015) 0.84
Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application. J Antimicrob Chemother (2013) 0.83
Advances in HIV microbicide development. Future Med Chem (2011) 0.81
Potential role of tenofovir vaginal gel for reduction of risk of herpes simplex virus in females. Int J Womens Health (2012) 0.81
The importance of the vaginal delivery route for antiretrovirals in HIV prevention. Ther Deliv (2011) 0.81
Sustained local delivery of structurally diverse HIV-1 microbicides released from sublimation enthalpy controlled matrices. Pharm Res (2012) 0.80
In search of the optimal delivery method for anti-HIV microbicides: are intravaginal rings the way forward? Expert Rev Anti Infect Ther (2013) 0.80
Sustained delivery of commensal bacteria from pod-intravaginal rings. Antimicrob Agents Chemother (2014) 0.78
Preparation and evaluation of intravaginal ring containing drospirenone. Adv Pharmacol Sci (2013) 0.78
The Promise of Intravaginal Rings for Prevention: User Perceptions of Biomechanical Properties and Implications for Prevention Product Development. PLoS One (2015) 0.77
Modified silicone elastomer vaginal gels for sustained release of antiretroviral HIV microbicides. J Pharm Sci (2014) 0.77
Development of polyether urethane intravaginal rings for the sustained delivery of hydroxychloroquine. Drug Des Devel Ther (2014) 0.77
Factors Important to the Prioritization and Development of Successful Topical Microbicides for HIV-1. Mol Biol Int (2012) 0.77
Poly(ethylene glycol) (PEG)-lactic acid nanocarrier-based degradable hydrogels for restoring the vaginal microenvironment. J Control Release (2014) 0.76
Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model. Antimicrob Agents Chemother (2017) 0.76
Polyethylene glycol-based hydrogels for controlled release of the antimicrobial subtilosin for prophylaxis of bacterial vaginosis. Antimicrob Agents Chemother (2014) 0.75
Sustained release of the candidate antiretroviral peptides T-1249 and JNJ54310516-AFP from a rod insert vaginal ring. Drug Deliv Transl Res (2016) 0.75
Development and in vitro/in vivo Evaluation of a Silastic Intravaginal Ring for Mifepristone Delivery. Indian J Pharm Sci (2015) 0.75
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science (2002) 9.59
American Society of Clinical Oncology identifies five key opportunities to improve care and reduce costs: the top five list for oncology. J Clin Oncol (2012) 7.16
American Society of Clinical Oncology guidance statement: the cost of cancer care. J Clin Oncol (2009) 6.77
American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol (2003) 6.66
American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol (2009) 4.95
Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N Engl J Med (2004) 4.84
American society of clinical oncology statement: toward individualized care for patients with advanced cancer. J Clin Oncol (2011) 4.64
American Society of Clinical Oncology 2006 update of the breast cancer follow-up and management guidelines in the adjuvant setting. J Clin Oncol (2006) 4.61
Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm. J Biol Chem (2009) 4.05
Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guideline. J Clin Oncol (2007) 3.91
Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer. J Clin Oncol (2006) 3.71
Early specialty palliative care--translating data in oncology into practice. N Engl J Med (2013) 3.58
The role of chemotherapy at the end of life: "when is enough, enough?". JAMA (2008) 3.31
2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer. J Clin Oncol (2011) 3.21
Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure (2008) 3.02
The shortage of essential chemotherapy drugs in the United States. N Engl J Med (2011) 2.74
Palliative care and oncology partnerships in real practice. Oncology (Williston Park) (2011) 2.72
Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol (2012) 2.62
Talking with patients about dying. N Engl J Med (2012) 2.34
Hospital mortality rates: how is palliative care taken into account? J Pain Symptom Manage (2010) 2.32
Arsenic methylation and skin cancer risk in southwestern Taiwan. J Occup Environ Med (2003) 2.11
Lung cancer in railroad workers exposed to diesel exhaust. Environ Health Perspect (2004) 2.06
Providing pain and palliative care education internationally. J Support Oncol (2011) 2.04
Lung cancer and elemental carbon exposure in trucking industry workers. Environ Health Perspect (2012) 2.04
Efficacy does not necessarily translate to cost effectiveness: a case study in the challenges associated with 21st-century cancer drug pricing. J Clin Oncol (2009) 2.03
Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J Acquir Immune Defic Syndr (2009) 1.89
Arsenic methylation and bladder cancer risk in Taiwan. Cancer Causes Control (2003) 1.86
Is it time for (survivorship care) plan B? J Clin Oncol (2011) 1.84
Residential exposure to petrochemicals and the risk of leukemia: using geographic information system tools to estimate individual-level residential exposure. Am J Epidemiol (2006) 1.84
SPIKE$: a six-step protocol for delivering bad news about the cost of medical care. J Clin Oncol (2008) 1.76
Spatial modeling of PM10 and NO2 in the continental United States, 1985-2000. Environ Health Perspect (2009) 1.73
Fatal Loeffler's endocarditis due to hypereosinophilic syndrome. Am J Hematol (2007) 1.73
The association of particulate air metal concentrations with heart rate variability. Environ Health Perspect (2002) 1.71
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase. J Biol Chem (2010) 1.68
Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase. J Biol Chem (2006) 1.64
Reasons why physicians do not have discussions about poor prognosis, why it matters, and what can be improved. J Clin Oncol (2012) 1.60
Assessment of optimal size and composition of the U.S. National Registry of hematopoietic stem cell donors. Transplantation (2004) 1.59
Lung cancer and vehicle exhaust in trucking industry workers. Environ Health Perspect (2008) 1.57
The nonnucleoside reverse transcriptase inhibitor UC-781 inhibits human immunodeficiency virus type 1 infection of human cervical tissue and dissemination by migratory cells. J Virol (2005) 1.54
Structure of antibody-neutralized murine norovirus and unexpected differences from viruslike particles. J Virol (2007) 1.49
Improving the quality of cancer care: implications for palliative care. J Palliat Med (2014) 1.49
Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques. Antimicrob Agents Chemother (2011) 1.48
Randomized trial of long-term follow-up for early-stage breast cancer: a comparison of family physician versus specialist care. J Clin Oncol (2006) 1.48
American Society of Clinical Oncology recommendations for the initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer. J Clin Oncol (2004) 1.44
Pharmacokinetic assessment of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS Res Hum Retroviruses (2010) 1.44
A randomized phase III study of radiotherapy alone or with 5-fluorouracil and mitomycin-C in patients with locally advanced adenocarcinoma of the pancreas: Eastern Cooperative Oncology Group study E8282. Int J Radiat Oncol Biol Phys (2005) 1.43
'Futile care': what to do when your patient insists on chemotherapy that likely won't help. Oncology (Williston Park) (2008) 1.42
Advance Care Planning Discussions: Why They Should Happen, Why They Don't, and How We Can Facilitate the Process. Oncology (Williston Park) (2015) 1.40
A case of inaccurate prognostication after the ARCTIC protocol. J Pain Symptom Manage (2012) 1.39
The association between personal measurements of environmental exposure to particulates and heart rate variability. Epidemiology (2002) 1.38
Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring. Antimicrob Agents Chemother (2011) 1.38
An antibody to the putative aphid recognition site on cucumber mosaic virus recognizes pentons but not hexons. J Virol (2002) 1.35
Differential antifungal and calcium channel-blocking activity among structurally related plant defensins. Plant Physiol (2004) 1.35
Paradoxes in advance care planning: the complex relationship of oncology patients, their physicians, and advance medical directives. J Clin Oncol (2009) 1.30
Structural determinants of metal specificity in the zinc transport protein ZnuA from synechocystis 6803. J Mol Biol (2003) 1.30
Scrambler therapy may relieve chronic neuropathic pain more effectively than guideline-based drug management: results of a pilot, randomized, controlled trial. J Pain Symptom Manage (2011) 1.29
Long-term ambient multipollutant exposures and mortality. Am J Respir Crit Care Med (2010) 1.29
Historical estimation of diesel exhaust exposure in a cohort study of U.S. railroad workers and lung cancer. Cancer Causes Control (2006) 1.26
A safety and pharmacokinetic trial assessing delivery of dapivirine from a vaginal ring in healthy women. AIDS (2014) 1.25
Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle. J Virol (2012) 1.21
Cause-specific mortality in the unionized U.S. trucking industry. Environ Health Perspect (2007) 1.20
SusG: a unique cell-membrane-associated alpha-amylase from a prominent human gut symbiont targets complex starch molecules. Structure (2010) 1.20
Summary of the findings from the exposure assessments for metalworking fluid mortality and morbidity studies. Appl Occup Environ Hyg (2003) 1.19
High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domains. J Virol (2010) 1.19
Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. J Biol Chem (2009) 1.17
An intravaginal ring for the simultaneous delivery of multiple drugs. J Pharm Sci (2012) 1.17
Human rhinovirus capsid dynamics is controlled by canyon flexibility. Virology (2003) 1.14
Skin exposure to isocyanates: reasons for concern. Environ Health Perspect (2006) 1.14
High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain. J Virol (2010) 1.13
The future of HIV microbicides: challenges and opportunities. Antivir Chem Chemother (2009) 1.13
Safety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques. Antimicrob Agents Chemother (2012) 1.11
The structure of a cyanobacterial bicarbonate transport protein, CmpA. J Biol Chem (2006) 1.11
Tenofovir and tenofovir disoproxil fumarate pharmacokinetics from intravaginal rings. AIDS (2012) 1.10
Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation. Biochemistry (2003) 1.10
Comparison of fine particle measurements from a direct-reading instrument and a gravimetric sampling method. J Occup Environ Hyg (2004) 1.09
Wiser use of dose-dense adjuvant therapy in breast cancer. J Clin Oncol (2012) 1.09
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. Biochem J (2002) 1.08
Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont. Biochemistry (2009) 1.08
Cotton dust and endotoxin levels in three Shanghai textile factories: a comparison of samplers. J Occup Environ Hyg (2006) 1.07
Microbial biofilms on the surface of intravaginal rings worn in non-human primates. J Med Microbiol (2011) 1.07
Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water. Cancer Epidemiol Biomarkers Prev (2005) 1.06
Vehicle traffic as a source of particulate polycyclic aromatic hydrocarbon exposure in the Mexico City metropolitan area. Environ Sci Technol (2004) 1.05
Using claims-based measures to predict performance status score in patients with lung cancer. Cancer (2010) 1.05
Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization. J Virol (2009) 1.05
Evidence-based palliative care in the intensive care unit: a systematic review of interventions. J Palliat Med (2014) 1.05
Do the large benefits justify the large costs of adjuvant breast cancer trastuzumab? J Clin Oncol (2007) 1.03
Palliative care consultation and hospital length of stay. J Palliat Med (2010) 1.03
The structure and allosteric regulation of mammalian glutamate dehydrogenase. Arch Biochem Biophys (2011) 1.03
Lead burden and psychiatric symptoms and the modifying influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism: the VA Normative Aging Study. Am J Epidemiol (2007) 1.02
Tracking personal exposure to particulate diesel exhaust in a diesel freight terminal using organic tracer analysis. J Expo Sci Environ Epidemiol (2008) 1.02
Pilot evaluation of Scrambler therapy for the treatment of chemotherapy-induced peripheral neuropathy. Support Care Cancer (2014) 1.02
Structure-activity determinants in antifungal plant defensins MsDef1 and MtDef4 with different modes of action against Fusarium graminearum. PLoS One (2011) 1.01
Possible regulatory role for the histidine-rich loop in the zinc transport protein, ZnuA. Biochemistry (2007) 1.01
Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity. Proc Natl Acad Sci U S A (2006) 1.01
Smoking behavior in trucking industry workers. Am J Ind Med (2006) 1.01
Using a water-immiscible ionic liquid to improve asymmetric reduction of 4-(trimethylsilyl)-3-butyn-2-one catalyzed by immobilized Candida parapsilosis CCTCC M203011 cells. BMC Biotechnol (2009) 0.99
Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation. Biochemistry (2004) 0.99
Remediation of chromium(VI) by a methane-oxidizing bacterium. Environ Sci Technol (2010) 0.99
The future of HIV prevention: prospects for an effective anti-HIV microbicide. Infect Dis Clin North Am (2007) 0.99