Scrambler therapy may relieve chronic neuropathic pain more effectively than guideline-based drug management: results of a pilot, randomized, controlled trial.

PubWeight™: 1.29‹?› | Rank: Top 10%

🔗 View Article (PMID 21763099)

Published in J Pain Symptom Manage on July 16, 2011

Authors

Giuseppe Marineo1, Vittorio Iorno, Cristiano Gandini, Vincenzo Moschini, Thomas J Smith

Author Affiliations

1: Delta Research & Development, Centro Ricerche Bioingegneria Medica, University of Rome "Tor Vergata," Rome, Italy. tsmit136@jhmi.edu

Articles citing this

Impact of Scrambler Therapy on Pain Management and Quality of Life in Cancer Patients: A Study of Twenty Cases. Indian J Palliat Care (2017) 1.39

Inaccuracy in the article "Managing chronic pain: results from an open-label study using MC5-A Calmare device in Support Care Cancer". Support Care Cancer (2011) 1.38

Pilot evaluation of Scrambler therapy for the treatment of chemotherapy-induced peripheral neuropathy. Support Care Cancer (2014) 1.02

A trial of Scrambler therapy in the treatment of cancer pain syndromes and chronic chemotherapy-induced peripheral neuropathy. J Pain Palliat Care Pharmacother (2013) 0.98

Breast cancer pain management - a review of current & novel therapies. Indian J Med Res (2014) 0.97

Overview of neuropathy associated with taxanes for the treatment of metastatic breast cancer. Cancer Chemother Pharmacol (2015) 0.94

Clinical experiences on the effect of scrambler therapy for patients with postherpetic neuralgia. Korean J Pain (2013) 0.91

Scrambler Therapy for the management of chronic pain. Support Care Cancer (2016) 0.88

Scrambler therapy for patients with cancer pain - case series -. Korean J Pain (2013) 0.86

Pilot evaluation of scrambler therapy for pain induced by bone and visceral metastases and refractory to standard therapies. Support Care Cancer (2015) 0.86

Failed back surgery syndrome: current perspectives. J Pain Res (2016) 0.85

Management options for established chemotherapy-induced peripheral neuropathy. Support Care Cancer (2014) 0.84

Post-herpetic neuralgia. Int J Gen Med (2012) 0.82

Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model. Stem Cell Res Ther (2016) 0.82

Understanding Neuropathic Corneal Pain-Gaps and Current Therapeutic Approaches. Semin Ophthalmol (2016) 0.79

Evaluating the impact of chemotherapy-induced peripheral neuropathy symptoms (CIPN-sx) on perceived ability to work in breast cancer survivors during the first year post-treatment. Support Care Cancer (2016) 0.77

Use of Scrambler Therapy in Acute Paediatric Pain: A Case Report and Review of the Literature. Case Rep Pediatr (2016) 0.75

Management of total cancer pain: a case of young adult. Indian J Palliat Care (2014) 0.75

Symptom management in the older adult: 2015 update. Clin Geriatr Med (2015) 0.75

Articles by these authors

(truncated to the top 100)

The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science (2002) 9.59

American Society of Clinical Oncology identifies five key opportunities to improve care and reduce costs: the top five list for oncology. J Clin Oncol (2012) 7.16

American Society of Clinical Oncology guidance statement: the cost of cancer care. J Clin Oncol (2009) 6.77

American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol (2003) 6.66

American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol (2009) 4.95

Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N Engl J Med (2004) 4.84

American society of clinical oncology statement: toward individualized care for patients with advanced cancer. J Clin Oncol (2011) 4.64

American Society of Clinical Oncology 2006 update of the breast cancer follow-up and management guidelines in the adjuvant setting. J Clin Oncol (2006) 4.61

Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm. J Biol Chem (2009) 4.05

Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guideline. J Clin Oncol (2007) 3.91

Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer. J Clin Oncol (2006) 3.71

Early specialty palliative care--translating data in oncology into practice. N Engl J Med (2013) 3.58

The role of chemotherapy at the end of life: "when is enough, enough?". JAMA (2008) 3.31

2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer. J Clin Oncol (2011) 3.21

Implementing a global integrative rehabilitation medicine rotation: a physical medicine and rehabilitation residency program's experience. Am J Phys Med Rehabil (2013) 3.09

Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure (2008) 3.02

The shortage of essential chemotherapy drugs in the United States. N Engl J Med (2011) 2.74

Palliative care and oncology partnerships in real practice. Oncology (Williston Park) (2011) 2.72

Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol (2012) 2.62

Talking with patients about dying. N Engl J Med (2012) 2.34

Hospital mortality rates: how is palliative care taken into account? J Pain Symptom Manage (2010) 2.32

Arsenic methylation and skin cancer risk in southwestern Taiwan. J Occup Environ Med (2003) 2.11

Lung cancer in railroad workers exposed to diesel exhaust. Environ Health Perspect (2004) 2.06

Lung cancer and elemental carbon exposure in trucking industry workers. Environ Health Perspect (2012) 2.04

Providing pain and palliative care education internationally. J Support Oncol (2011) 2.04

Efficacy does not necessarily translate to cost effectiveness: a case study in the challenges associated with 21st-century cancer drug pricing. J Clin Oncol (2009) 2.03

Arsenic methylation and bladder cancer risk in Taiwan. Cancer Causes Control (2003) 1.86

Is it time for (survivorship care) plan B? J Clin Oncol (2011) 1.84

Residential exposure to petrochemicals and the risk of leukemia: using geographic information system tools to estimate individual-level residential exposure. Am J Epidemiol (2006) 1.84

Advances in microbicide vaginal rings. Antiviral Res (2010) 1.76

SPIKE$: a six-step protocol for delivering bad news about the cost of medical care. J Clin Oncol (2008) 1.76

Spatial modeling of PM10 and NO2 in the continental United States, 1985-2000. Environ Health Perspect (2009) 1.73

Fatal Loeffler's endocarditis due to hypereosinophilic syndrome. Am J Hematol (2007) 1.73

The association of particulate air metal concentrations with heart rate variability. Environ Health Perspect (2002) 1.71

Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase. J Biol Chem (2010) 1.68

Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase. J Biol Chem (2006) 1.64

Reasons why physicians do not have discussions about poor prognosis, why it matters, and what can be improved. J Clin Oncol (2012) 1.60

Assessment of optimal size and composition of the U.S. National Registry of hematopoietic stem cell donors. Transplantation (2004) 1.59

Lung cancer and vehicle exhaust in trucking industry workers. Environ Health Perspect (2008) 1.57

Improving the quality of cancer care: implications for palliative care. J Palliat Med (2014) 1.49

Structure of antibody-neutralized murine norovirus and unexpected differences from viruslike particles. J Virol (2007) 1.49

Randomized trial of long-term follow-up for early-stage breast cancer: a comparison of family physician versus specialist care. J Clin Oncol (2006) 1.48

American Society of Clinical Oncology recommendations for the initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer. J Clin Oncol (2004) 1.44

A randomized phase III study of radiotherapy alone or with 5-fluorouracil and mitomycin-C in patients with locally advanced adenocarcinoma of the pancreas: Eastern Cooperative Oncology Group study E8282. Int J Radiat Oncol Biol Phys (2005) 1.43

'Futile care': what to do when your patient insists on chemotherapy that likely won't help. Oncology (Williston Park) (2008) 1.42

Advance Care Planning Discussions: Why They Should Happen, Why They Don't, and How We Can Facilitate the Process. Oncology (Williston Park) (2015) 1.40

A case of inaccurate prognostication after the ARCTIC protocol. J Pain Symptom Manage (2012) 1.39

The association between personal measurements of environmental exposure to particulates and heart rate variability. Epidemiology (2002) 1.38

Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring. Antimicrob Agents Chemother (2011) 1.38

An antibody to the putative aphid recognition site on cucumber mosaic virus recognizes pentons but not hexons. J Virol (2002) 1.35

Differential antifungal and calcium channel-blocking activity among structurally related plant defensins. Plant Physiol (2004) 1.35

Paradoxes in advance care planning: the complex relationship of oncology patients, their physicians, and advance medical directives. J Clin Oncol (2009) 1.30

Structural determinants of metal specificity in the zinc transport protein ZnuA from synechocystis 6803. J Mol Biol (2003) 1.30

Long-term ambient multipollutant exposures and mortality. Am J Respir Crit Care Med (2010) 1.29

Historical estimation of diesel exhaust exposure in a cohort study of U.S. railroad workers and lung cancer. Cancer Causes Control (2006) 1.26

Re: Alternative medicines: yes; alternatives to medicine: no. Am J Phys Med Rehabil (2013) 1.25

Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle. J Virol (2012) 1.21

Cause-specific mortality in the unionized U.S. trucking industry. Environ Health Perspect (2007) 1.20

SusG: a unique cell-membrane-associated alpha-amylase from a prominent human gut symbiont targets complex starch molecules. Structure (2010) 1.20

Summary of the findings from the exposure assessments for metalworking fluid mortality and morbidity studies. Appl Occup Environ Hyg (2003) 1.19

High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domains. J Virol (2010) 1.19

Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. J Biol Chem (2009) 1.17

An intravaginal ring for the simultaneous delivery of multiple drugs. J Pharm Sci (2012) 1.17

Human rhinovirus capsid dynamics is controlled by canyon flexibility. Virology (2003) 1.14

Skin exposure to isocyanates: reasons for concern. Environ Health Perspect (2006) 1.14

High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain. J Virol (2010) 1.13

Safety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques. Antimicrob Agents Chemother (2012) 1.11

The structure of a cyanobacterial bicarbonate transport protein, CmpA. J Biol Chem (2006) 1.11

Tenofovir and tenofovir disoproxil fumarate pharmacokinetics from intravaginal rings. AIDS (2012) 1.10

Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation. Biochemistry (2003) 1.10

Comparison of fine particle measurements from a direct-reading instrument and a gravimetric sampling method. J Occup Environ Hyg (2004) 1.09

Wiser use of dose-dense adjuvant therapy in breast cancer. J Clin Oncol (2012) 1.09

Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. Biochem J (2002) 1.08

Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont. Biochemistry (2009) 1.08

Cotton dust and endotoxin levels in three Shanghai textile factories: a comparison of samplers. J Occup Environ Hyg (2006) 1.07

Microbial biofilms on the surface of intravaginal rings worn in non-human primates. J Med Microbiol (2011) 1.07

Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water. Cancer Epidemiol Biomarkers Prev (2005) 1.06

Vehicle traffic as a source of particulate polycyclic aromatic hydrocarbon exposure in the Mexico City metropolitan area. Environ Sci Technol (2004) 1.05

Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization. J Virol (2009) 1.05

Using claims-based measures to predict performance status score in patients with lung cancer. Cancer (2010) 1.05

Evidence-based palliative care in the intensive care unit: a systematic review of interventions. J Palliat Med (2014) 1.05

Do the large benefits justify the large costs of adjuvant breast cancer trastuzumab? J Clin Oncol (2007) 1.03

Palliative care consultation and hospital length of stay. J Palliat Med (2010) 1.03

The structure and allosteric regulation of mammalian glutamate dehydrogenase. Arch Biochem Biophys (2011) 1.03

Lead burden and psychiatric symptoms and the modifying influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism: the VA Normative Aging Study. Am J Epidemiol (2007) 1.02

Tracking personal exposure to particulate diesel exhaust in a diesel freight terminal using organic tracer analysis. J Expo Sci Environ Epidemiol (2008) 1.02

Pilot evaluation of Scrambler therapy for the treatment of chemotherapy-induced peripheral neuropathy. Support Care Cancer (2014) 1.02

Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity. Proc Natl Acad Sci U S A (2006) 1.01

Smoking behavior in trucking industry workers. Am J Ind Med (2006) 1.01

Possible regulatory role for the histidine-rich loop in the zinc transport protein, ZnuA. Biochemistry (2007) 1.01

Structure-activity determinants in antifungal plant defensins MsDef1 and MtDef4 with different modes of action against Fusarium graminearum. PLoS One (2011) 1.01

Using a water-immiscible ionic liquid to improve asymmetric reduction of 4-(trimethylsilyl)-3-butyn-2-one catalyzed by immobilized Candida parapsilosis CCTCC M203011 cells. BMC Biotechnol (2009) 0.99

Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation. Biochemistry (2004) 0.99

Remediation of chromium(VI) by a methane-oxidizing bacterium. Environ Sci Technol (2010) 0.99

Survival among non-small cell lung cancer patients with poor performance status after first line chemotherapy. Lung Cancer (2012) 0.98

Multidomain Carbohydrate-binding Proteins Involved in Bacteroides thetaiotaomicron Starch Metabolism. J Biol Chem (2012) 0.98

Land crabs as key drivers in tropical coastal forest recruitment. Biol Rev Camb Philos Soc (2009) 0.98

A trial of Scrambler therapy in the treatment of cancer pain syndromes and chronic chemotherapy-induced peripheral neuropathy. J Pain Palliat Care Pharmacother (2013) 0.98

Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site. J Biol Chem (2011) 0.98