Published in Curr Biol on September 05, 2006
Examining the link between chromosomal instability and aneuploidy in human cells. J Cell Biol (2008) 4.95
The life and miracles of kinetochores. EMBO J (2009) 4.59
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nat Cell Biol (2008) 4.15
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J Cell Biol (2010) 3.50
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism. J Cell Biol (2010) 3.28
Mechanisms of chromosomal instability. Curr Biol (2010) 3.21
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol (2012) 2.99
Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol (2010) 2.88
Traffic control: regulation of kinesin motors. Nat Rev Mol Cell Biol (2009) 2.87
Deviant kinetochore microtubule dynamics underlie chromosomal instability. Curr Biol (2009) 2.83
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell (2007) 2.25
The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Mol Biol Cell (2007) 2.19
Katanin contributes to interspecies spindle length scaling in Xenopus. Cell (2011) 2.16
Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres. Genes Dev (2007) 2.06
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly. J Cell Biol (2008) 1.91
Correcting aberrant kinetochore microtubule attachments: an Aurora B-centric view. Curr Opin Cell Biol (2009) 1.83
Kinetochore-microtubule interactions: the means to the end. Curr Opin Cell Biol (2008) 1.80
Dual role of topoisomerase II in centromere resolution and aurora B activity. PLoS Biol (2008) 1.79
Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis. J Cell Sci (2011) 1.79
Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function. Mol Biol Cell (2007) 1.66
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal (2011) 1.62
Merotelic kinetochore attachment: causes and effects. Trends Cell Biol (2011) 1.60
MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover. J Cell Biol (2007) 1.58
Active transcription and essential role of RNA polymerase II at the centromere during mitosis. Proc Natl Acad Sci U S A (2012) 1.50
S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase. Cell (2013) 1.49
Aurora kinase inhibitors: progress towards the clinic. Invest New Drugs (2012) 1.44
Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes. PLoS One (2008) 1.43
Feedback control in sensing chromosome biorientation by the Aurora B kinase. Curr Biol (2011) 1.40
Making an effective switch at the kinetochore by phosphorylation and dephosphorylation. Chromosoma (2013) 1.39
Aurora controls sister kinetochore mono-orientation and homolog bi-orientation in meiosis-I. EMBO J (2007) 1.38
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation. J Cell Biol (2011) 1.35
Cell division: control of the chromosomal passenger complex in time and space. Chromosoma (2013) 1.34
The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation. Curr Biol (2007) 1.33
Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a. J Cell Sci (2009) 1.30
Kinetochore-microtubule interactions: steps towards bi-orientation. EMBO J (2010) 1.30
Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation. PLoS One (2009) 1.27
Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules. Semin Cell Dev Biol (2010) 1.25
A chemical tool box defines mitotic and interphase roles for Mps1 kinase. J Cell Biol (2010) 1.25
PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity. J Biol Chem (2010) 1.24
The interplay of the N- and C-terminal domains of MCAK control microtubule depolymerization activity and spindle assembly. Mol Biol Cell (2006) 1.21
Chromosomes and cancer cells. Chromosome Res (2011) 1.21
Synchronizing chromosome segregation by flux-dependent force equalization at kinetochores. J Cell Biol (2009) 1.20
The Ndc80 kinetochore complex directly modulates microtubule dynamics. Proc Natl Acad Sci U S A (2012) 1.20
Bi-orienting chromosomes: acrobatics on the mitotic spindle. Chromosoma (2008) 1.19
The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex. Mol Biol Cell (2009) 1.15
Functional and spatial regulation of mitotic centromere-associated kinesin by cyclin-dependent kinase 1. Mol Cell Biol (2010) 1.13
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target. Oncotarget (2011) 1.13
Phosphorylation at serine 331 is required for Aurora B activation. J Cell Biol (2011) 1.10
Towards a quantitative understanding of mitotic spindle assembly and mechanics. J Cell Sci (2010) 1.10
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation. Mol Biol Cell (2012) 1.10
How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays. Semin Cell Dev Biol (2010) 1.10
ICIS and Aurora B coregulate the microtubule depolymerase Kif2a. Curr Biol (2009) 1.08
Regulation of kinetochore-microtubule attachments through homeostatic control during mitosis. Nat Rev Mol Cell Biol (2014) 1.08
Finding the middle ground: how kinetochores power chromosome congression. Cell Mol Life Sci (2010) 1.04
Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells. Mol Biol Cell (2008) 1.02
Regulation of localization and activity of the microtubule depolymerase MCAK. Bioarchitecture (2011) 1.01
Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1. PLoS One (2011) 1.01
MCAK and paclitaxel have differential effects on spindle microtubule organization and dynamics. Mol Biol Cell (2009) 1.01
Modeling the temporal evolution of the spindle assembly checkpoint and role of Aurora B kinase. Proc Natl Acad Sci U S A (2008) 1.01
A stochastic model of kinetochore-microtubule attachment accurately describes fission yeast chromosome segregation. J Cell Biol (2012) 1.00
The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond. Cell Div (2008) 0.99
Linked in: formation and regulation of microtubule attachments during chromosome segregation. Curr Opin Cell Biol (2014) 0.97
The elegans of spindle assembly. Cell Mol Life Sci (2010) 0.96
Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation. Cell Cycle (2011) 0.94
Australin: a chromosomal passenger protein required specifically for Drosophila melanogaster male meiosis. J Cell Biol (2008) 0.92
Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation. Sci Rep (2015) 0.92
Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation. Oncogene (2013) 0.91
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling. Front Oncol (2015) 0.91
Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells. Cell Cycle (2015) 0.90
Spatiotemporal organization of Aurora-B by APC/CCdh1 after mitosis coordinates cell spreading through FHOD1. J Cell Sci (2013) 0.89
Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells. J Cell Biol (2014) 0.89
Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells. FASEB J (2012) 0.89
EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B. J Cell Biol (2014) 0.89
Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase. J Biol Chem (2010) 0.89
Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis. Traffic (2014) 0.88
NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity. Sci Rep (2016) 0.87
MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I. Development (2010) 0.87
Cell cycle dependent degradation of MCAK: evidence against a role in anaphase chromosome movement. Cell Cycle (2008) 0.87
Localized Aurora B activity spatially controls non-kinetochore microtubules during spindle assembly. Chromosoma (2011) 0.85
RNA stimulates Aurora B kinase activity during mitosis. PLoS One (2014) 0.84
The molecular basis for kinesin functional specificity during mitosis. Cytoskeleton (Hoboken) (2013) 0.84
A mitotic role for the DNA damage-responsive CHK2 kinase. Nat Cell Biol (2010) 0.84
Aurora B regulates spindle bipolarity in meiosis in vertebrate oocytes. Cell Cycle (2012) 0.84
Aurora B prevents chromosome arm separation defects by promoting telomere dispersion and disjunction. J Cell Biol (2015) 0.84
TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes. Open Biol (2014) 0.83
Maturation of the kinetochore-microtubule interface and the meaning of metaphase. Chromosome Res (2012) 0.83
ATRX contributes to epigenetic asymmetry and silencing of major satellite transcripts in the maternal genome of the mouse embryo. Development (2015) 0.81
Mammalian chromosomes contain cis-acting elements that control replication timing, mitotic condensation, and stability of entire chromosomes. Bioessays (2012) 0.81
A role for metaphase spindle elongation forces in correction of merotelic kinetochore attachments. Curr Biol (2012) 0.81
Mitosis puts sisters in a strained relationship: force generation at the kinetochore. Exp Cell Res (2012) 0.80
Centrosomes in spindle organization and chromosome segregation: a mechanistic view. Chromosome Res (2016) 0.79
Regulatory mechanisms that control mitotic kinesins. Exp Cell Res (2015) 0.79
New insights into the mechanism for chromosome alignment in metaphase. Int Rev Cell Mol Biol (2013) 0.79
Correction of microtubule-kinetochore attachment errors: mechanisms and role in tumor suppression. Semin Cell Dev Biol (2011) 0.79
Mitosis phase enrichment with identification of mitotic centromere-associated kinesin as a therapeutic target in castration-resistant prostate cancer. PLoS One (2012) 0.78
TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation. Mol Cell Biol (2014) 0.78
Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy. Oncotarget (2015) 0.78
The KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegans. PLoS One (2015) 0.78
Mechanisms to Avoid and Correct Erroneous Kinetochore-Microtubule Attachments. Biology (Basel) (2017) 0.78
Formin mDia3: A novel target for Aurora B kinase. Bioarchitecture (2011) 0.77
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol (2002) 8.37
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol (2004) 6.61
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity. Curr Biol (2004) 4.20
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature (2008) 3.77
Protein architecture of the human kinetochore microtubule attachment site. Cell (2009) 3.68
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr Biol (2002) 3.17
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol Cell (2005) 3.14
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. Science (2010) 3.13
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev (2003) 3.04
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol Biol Cell (2002) 2.56
Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1). Curr Biol (2008) 2.38
The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol (2004) 2.31
Phosphorylation regulates SIRT1 function. PLoS One (2008) 2.30
Centromeric Aurora-B activation requires TD-60, microtubules, and substrate priming phosphorylation. Science (2008) 2.28
The reversibility of mitotic exit in vertebrate cells. Nature (2006) 2.16
Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. J Cell Biol (2010) 2.05
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell (2010) 2.00
Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition. Cell (2007) 1.97
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly. J Cell Biol (2008) 1.91
Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores. Curr Biol (2005) 1.88
INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila. Dev Cell (2006) 1.71
Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function. Mol Biol Cell (2007) 1.66
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal (2011) 1.62
Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore. Mol Biol Cell (2005) 1.52
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. Proc Natl Acad Sci U S A (2004) 1.51
Complement activation on B lymphocytes opsonized with rituximab or ofatumumab produces substantial changes in membrane structure preceding cell lysis. J Immunol (2008) 1.46
Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin. Chromosoma (2007) 1.32
Spindle poisons and cell fate: a tale of two pathways. Mol Interv (2011) 1.24
Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae. Eukaryot Cell (2005) 1.24
Linking kinetochore-microtubule binding to the spindle checkpoint. Dev Cell (2008) 1.21
Timing of events in mitosis. Curr Biol (2002) 1.20
Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment. Cell (2007) 1.17
Multimodal microtubule binding by the Ndc80 kinetochore complex. Nat Struct Mol Biol (2012) 1.15
The Ndc80 complex: integrating the kinetochore's many movements. Chromosome Res (2011) 1.11
ICIS and Aurora B coregulate the microtubule depolymerase Kif2a. Curr Biol (2009) 1.08
Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1. Cell Cycle (2007) 1.07
The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein. J Cell Biol (2011) 1.07
Cep57, a multidomain protein with unique microtubule and centrosomal localization domains. Biochem J (2008) 1.06
The Ndc80 complex uses a tripartite attachment point to couple microtubule depolymerization to chromosome movement. Mol Biol Cell (2011) 1.05
Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells. Mol Biol Cell (2008) 1.02
A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint. Genes Dev (2012) 0.96
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres. Chromosoma (2008) 0.94
Aurora-A kinase and inhibitor-2 regulate the cyclin threshold for mitotic entry in Xenopus early embryonic cell cycles. Cell Cycle (2006) 0.92
Centriole duplication: A lesson in self-control. Cell Cycle (2010) 0.92
Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol Biol Cell (2012) 0.91
The kinetochore NUPtials. Nat Cell Biol (2003) 0.90
Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor. Biochemistry (2012) 0.90
A Hec of a microtubule attachment. Nat Struct Mol Biol (2007) 0.89
Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins. Biochemistry (2007) 0.89
EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B. J Cell Biol (2014) 0.89
Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers. Eur J Immunol (2011) 0.88
The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts. Nucleus (2015) 0.81
Structural features and chaperone activity of the NudC protein family. J Mol Biol (2011) 0.81
Purification of the Ndc80 kinetochore subcomplex from Xenopus eggs. Methods Mol Biol (2005) 0.78
Cdt1 throws kinetochore-microtubule attachments for a loop. Nat Cell Biol (2012) 0.77
Probing kinetochore structure and function using Xenopus laevis frog egg extracts. Methods Mol Biol (2009) 0.76
The quest for the holy "G" of chromosomal passengers. Dev Cell (2003) 0.75
Xenopus egg extracts as a simplified model system for structure-function studies of dynein regulators. Methods Mol Biol (2014) 0.75
A new histone at the centromere? Cell (2012) 0.75
Cell division: righting the check. Curr Biol (2009) 0.75