Published in Dev Cell on September 07, 2006
mTOR signaling in growth control and disease. Cell (2012) 29.21
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol (2009) 9.63
mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci (2009) 5.04
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. EMBO J (2008) 4.79
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J (2008) 4.49
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). Biochem J (2009) 4.12
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity (2010) 4.06
mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell (2009) 3.78
The TSC1-TSC2 complex is required for proper activation of mTOR complex 2. Mol Cell Biol (2008) 3.50
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev (2009) 3.42
mTOR and cancer: many loops in one pathway. Curr Opin Cell Biol (2009) 3.22
Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Biochem J (2007) 3.08
PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis. Curr Biol (2008) 3.06
The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function. Nat Immunol (2011) 3.03
TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Cancer Res (2009) 2.96
Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony. J Biol Chem (2010) 2.90
mTOR complex 2 signaling and functions. Cell Cycle (2011) 2.66
mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling. Mol Cell Biol (2009) 2.57
mTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion. Dev Cell (2010) 2.56
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. EMBO J (2010) 2.35
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity. Mol Cell Biol (2007) 2.32
Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism. Diabetes (2010) 2.30
Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy. Oncogene (2010) 2.22
Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1. PLoS Biol (2009) 2.15
TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation. Mol Cell (2011) 2.13
PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS One (2007) 2.07
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. Cell Stem Cell (2012) 2.06
mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proc Natl Acad Sci U S A (2009) 2.05
mTORC2 controls actin polymerization required for consolidation of long-term memory. Nat Neurosci (2013) 2.04
Physiological regulation of Akt activity and stability. Am J Transl Res (2010) 1.95
Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction. Am J Pathol (2008) 1.94
Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth. Genes Dev (2007) 1.83
The coordination of nuclear and mitochondrial communication during aging and calorie restriction. Ageing Res Rev (2009) 1.79
A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2. J Biol Chem (2010) 1.75
TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion. J Cell Sci (2012) 1.74
Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1. Mol Cell Biol (2009) 1.58
Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem (2011) 1.56
Rapamycin and mTOR kinase inhibitors. J Chem Biol (2008) 1.51
Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion. Mol Biol Cell (2007) 1.47
Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. J Exp Med (2012) 1.44
mTOR signaling for biological control and cancer. J Cell Physiol (2013) 1.40
Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication. J Virol (2010) 1.38
Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies. Mol Cancer Ther (2008) 1.38
Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. Diabetes (2011) 1.37
The translational landscape of the mammalian cell cycle. Mol Cell (2013) 1.36
mTORC2 is required for proliferation and survival of TSC2-null cells. Mol Cell Biol (2011) 1.36
Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology. J Cell Biol (2013) 1.35
Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction. Mol Cell (2010) 1.34
Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2. J Biol Chem (2012) 1.33
Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1. J Biol Chem (2011) 1.31
Staying alive: metabolic adaptations to quiescence. Cell Cycle (2012) 1.28
Endoplasmic reticulum and Golgi localization sequences for mammalian target of rapamycin. Mol Biol Cell (2007) 1.28
An emerging role for TOR signaling in mammalian tissue and stem cell physiology. Development (2011) 1.27
Hot topics in aging research: protein translation, 2009. Aging Cell (2009) 1.24
mTOR-dependent cell survival mechanisms. Cold Spring Harb Perspect Biol (2012) 1.24
Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage. J Cell Biol (2008) 1.24
Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner. Mol Cell Biol (2007) 1.23
Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons. Neuron (2011) 1.21
mTOR signaling and its roles in normal and abnormal brain development. Front Mol Neurosci (2014) 1.19
Review series: TOR kinase complexes and cell migration. J Cell Biol (2011) 1.19
The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway. EMBO J (2009) 1.18
TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells. BMC Cancer (2008) 1.18
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice. PLoS Biol (2010) 1.16
A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Mol Cell Biol (2008) 1.15
Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2. Mol Cancer Res (2010) 1.15
mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]. J Biol Chem (2011) 1.14
Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex. Hum Mol Genet (2012) 1.10
Emerging evidence of a link between the polycystins and the mTOR pathways. Pathogenetics (2009) 1.09
Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination. J Neurosci (2014) 1.09
mTOR signaling in tumorigenesis. Biochim Biophys Acta (2014) 1.06
c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and -dependent mechanisms. PLoS One (2009) 1.06
Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging. Aging (Albany NY) (2012) 1.05
mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J (2015) 1.04
Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling. PLoS Genet (2010) 1.04
In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis. J Biol Chem (2008) 1.04
Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses. Proc Natl Acad Sci U S A (2012) 1.03
A critical role for Rictor in T lymphopoiesis. J Immunol (2012) 1.01
mTORC2 Caught in a SINful Akt. Dev Cell (2006) 1.00
mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells. Blood (2011) 0.99
Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation. Mol Cell Biol (2009) 0.99
Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling. Mol Cell Biol (2013) 0.99
mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition. Proc Natl Acad Sci U S A (2014) 0.98
Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells. PLoS One (2012) 0.98
BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation. Sci Signal (2013) 0.97
Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. PLoS One (2014) 0.97
Mammalian TOR signaling to the AGC kinases. Crit Rev Biochem Mol Biol (2011) 0.97
Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis. Mol Metab (2014) 0.96
mTORC2 signaling promotes skeletal growth and bone formation in mice. J Bone Miner Res (2015) 0.96
Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival. Cancer Prev Res (Phila) (2012) 0.96
AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia. J Mol Signal (2010) 0.96
PI3K/mTOR signaling regulates prostatic branching morphogenesis. Dev Biol (2011) 0.96
Frontier of epilepsy research - mTOR signaling pathway. Exp Mol Med (2011) 0.95
PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy. J Cell Physiol (2010) 0.95
Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival. PLoS One (2012) 0.95
Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation. Front Mol Neurosci (2014) 0.95
A conserved role of IQGAP1 in regulating TOR complex 1. J Cell Sci (2012) 0.94
mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif. J Biol Chem (2011) 0.93
S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1. Cell Rep (2012) 0.93
The mTOR (mammalian target of rapamycin) kinase maintains integrity of mTOR complex 2. J Biol Chem (2011) 0.91
MHC class I and integrin ligation induce ERK activation via an mTORC2-dependent pathway. Biochem Biophys Res Commun (2008) 0.91
Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells. Am J Physiol Endocrinol Metab (2002) 4.45
Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption. Nat Med (2005) 4.14
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity (2010) 4.06
Allosteric activators of glucokinase: potential role in diabetes therapy. Science (2003) 3.97
mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell (2009) 3.78
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. Proc Natl Acad Sci U S A (2004) 3.40
Control of pancreatic β cell regeneration by glucose metabolism. Cell Metab (2011) 3.35
Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis (2002) 3.21
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem (2004) 3.17
Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Biochem J (2007) 3.08
Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. Proc Natl Acad Sci U S A (2005) 2.60
Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. Nature (2002) 2.59
Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver. Cell Metab (2007) 2.47
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity. Mol Cell Biol (2007) 2.32
RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function. J Biol Chem (2005) 2.32
Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism. Diabetes (2010) 2.30
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes Dev (2006) 2.15
Of mice and MEN1: Insulinomas in a conditional mouse knockout. Mol Cell Biol (2003) 2.12
Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Development (2006) 2.09
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A (2009) 2.09
Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase. J Biol Chem (2003) 2.07
MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes (2010) 2.01
Differential structure of atrial and ventricular KATP: atrial KATP channels require SUR1. Circ Res (2008) 1.98
Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase. J Biol Chem (2004) 1.86
Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose. J Biol Chem (2002) 1.85
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Development (2013) 1.83
The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy. Diabetes (2006) 1.80
Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev (2007) 1.79
pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. Dev Biol (2007) 1.68
Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev Biol (2008) 1.67
Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number. Oncogene (2003) 1.62
Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol (2006) 1.61
Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. Mol Cell Biol (2003) 1.60
A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev (2008) 1.54
Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells. J Biol Chem (2005) 1.54
Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice. EMBO J (2003) 1.51
Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2005) 1.50
Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming. Genes Dev (2011) 1.48
Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene. Genesis (2005) 1.42
Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice. Hum Mol Genet (2005) 1.40
Hepatic energy state is regulated by glucagon receptor signaling in mice. J Clin Invest (2009) 1.39
Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro. Circulation (2011) 1.38
Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass. J Clin Invest (2003) 1.37
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet (2013) 1.37
Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. Diabetes (2011) 1.37
Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation. Diabetes (2003) 1.36
The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy. Diabetes (2002) 1.35
The prediabetic period: review of clinical aspects. Diabetes Metab J (2011) 1.34
Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations. Diabetes (2003) 1.33
Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues. Mol Cell Biol (2004) 1.29
Prevalence of chronic complications in korean patients with type 2 diabetes mellitus based on the korean national diabetes program. Diabetes Metab J (2011) 1.26
Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation. Mech Dev (2009) 1.23
Generation of a conditional allele of the mouse prostaglandin EP4 receptor. Genesis (2004) 1.22
Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse. Mech Dev (2007) 1.20
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. J Clin Invest (2015) 1.19
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice. PLoS Biol (2010) 1.16
Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice. Dis Model Mech (2011) 1.16
A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Mol Cell Biol (2008) 1.15
Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2. Mol Cancer Res (2010) 1.15
Rapid translocation of hepatic glucokinase in response to intraduodenal glucose infusion and changes in plasma glucose and insulin in conscious rats. Am J Physiol Gastrointest Liver Physiol (2003) 1.15
Targeted inactivation of hepatocyte growth factor receptor c-met in beta-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of beta-cell mass. Diabetes (2005) 1.14
Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels. Endocrinology (2011) 1.11
Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young. J Biol Chem (2005) 1.11
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation. EMBO J (2013) 1.11
Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells. Gastroenterology (2010) 1.09
Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice. Biochem Biophys Res Commun (2004) 1.07
Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas. Dev Biol (2011) 1.06
A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin. J Biol Chem (2002) 1.06
Efficient DNA cassette exchange in mouse embryonic stem cells by staggered positive-negative selection. Genesis (2004) 1.06
Evaluation of glycemic variability in well-controlled type 2 diabetes mellitus. Diabetes Technol Ther (2013) 1.05
Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Circulation (2008) 1.05
Impaired glucagon secretory responses in mice lacking the type 1 sulfonylurea receptor. Am J Physiol Endocrinol Metab (2005) 1.04
Dual lineage-specific expression of Sox17 during mouse embryogenesis. Stem Cells (2012) 1.03
Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine. Am J Physiol Endocrinol Metab (2004) 1.02
Mind bomb 1 is required for pancreatic β-cell formation. Proc Natl Acad Sci U S A (2012) 1.02
5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. Biochem Biophys Res Commun (2005) 1.01
Strategies for the use of site-specific recombinases in genome engineering. Methods Mol Med (2005) 0.99
Cholinergic regulation of fuel-induced hormone secretion and respiration of SUR1-/- mouse islets. Am J Physiol Endocrinol Metab (2006) 0.98
Obesity and the beta cell: lessons from leptin. J Clin Invest (2007) 0.97
Generation and functional confirmation of a conditional null PPARgamma allele in mice. Genesis (2002) 0.97
Ghrelin expression in the mouse pancreas defines a unique multipotent progenitor population. PLoS One (2012) 0.97
Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence. Biochem J (2008) 0.97
Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. Stem Cell Res (2013) 0.95
Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology. Genesis (2012) 0.93
Recombinase-mediated cassette exchange to rapidly and efficiently generate mice with human cardiac sodium channels. Genesis (2006) 0.93
Glucokinase thermolability and hepatic regulatory protein binding are essential factors for predicting the blood glucose phenotype of missense mutations. J Biol Chem (2007) 0.93