Evolution of sensory complexity recorded in a myxobacterial genome.

PubWeight™: 3.35‹?› | Rank: Top 1%

🔗 View Article (PMC 1622800)

Published in Proc Natl Acad Sci U S A on October 02, 2006

Authors

B S Goldman1, W C Nierman, D Kaiser, S C Slater, A S Durkin, J A Eisen, J Eisen, C M Ronning, W B Barbazuk, M Blanchard, C Field, C Halling, G Hinkle, O Iartchuk, H S Kim, C Mackenzie, R Madupu, N Miller, A Shvartsbeyn, S A Sullivan, M Vaudin, R Wiegand, H B Kaplan

Author Affiliations

1: Monsanto Company, St. Louis, MO 63167, USA. barry.s.golman@monsanto.com

Articles citing this

(truncated to the top 100)

Efficient de novo assembly of single-cell bacterial genomes from short-read data sets. Nat Biotechnol (2011) 5.60

Natural products version 2.0: connecting genes to molecules. J Am Chem Soc (2010) 3.06

Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes. PLoS Genet (2011) 2.54

Evolution of the chaperone/usher assembly pathway: fimbrial classification goes Greek. Microbiol Mol Biol Rev (2007) 2.44

Comparative genomic reconstruction of transcriptional regulatory networks in bacteria. Chem Rev (2007) 2.40

The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes. Proc Natl Acad Sci U S A (2007) 2.35

Deciphering the hunting strategy of a bacterial wolfpack. FEMS Microbiol Rev (2009) 1.58

Regulation of dev, an operon that includes genes essential for Myxococcus xanthus development and CRISPR-associated genes and repeats. J Bacteriol (2007) 1.56

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters. Appl Microbiol Biotechnol (2012) 1.50

Massive expansion of Ubiquitination-related gene families within the Chlamydiae. Mol Biol Evol (2014) 1.47

Cell contact-dependent outer membrane exchange in myxobacteria: genetic determinants and mechanism. PLoS Genet (2012) 1.46

Discovering the hidden secondary metabolome of Myxococcus xanthus: a study of intraspecific diversity. Appl Environ Microbiol (2008) 1.40

Rapid identification of high-confidence taxonomic assignments for metagenomic data. Nucleic Acids Res (2012) 1.39

Emergence and modular evolution of a novel motility machinery in bacteria. PLoS Genet (2011) 1.38

ClusterMine360: a database of microbial PKS/NRPS biosynthesis. Nucleic Acids Res (2012) 1.31

Two variable active site residues modulate response regulator phosphoryl group stability. Mol Microbiol (2008) 1.29

Hysteretic and graded responses in bacterial two-component signal transduction. Mol Microbiol (2008) 1.26

The mosaic genome of Anaeromyxobacter dehalogenans strain 2CP-C suggests an aerobic common ancestor to the delta-proteobacteria. PLoS One (2008) 1.25

Bactofilins, a ubiquitous class of cytoskeletal proteins mediating polar localization of a cell wall synthase in Caulobacter crescentus. EMBO J (2009) 1.23

Eukaryotic-like protein kinases in the prokaryotes and the myxobacterial kinome. Proc Natl Acad Sci U S A (2008) 1.23

Bioinformatics and experimental analysis of proteins of two-component systems in Myxococcus xanthus. J Bacteriol (2007) 1.21

Genomic insights into an obligate epibiotic bacterial predator: Micavibrio aeruginosavorus ARL-13. BMC Genomics (2011) 1.19

Extraordinary expansion of a Sorangium cellulosum genome from an alkaline milieu. Sci Rep (2013) 1.18

Single domain response regulators: molecular switches with emerging roles in cell organization and dynamics. Curr Opin Microbiol (2009) 1.17

The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation. Proc Natl Acad Sci U S A (2006) 1.15

CdnL, a member of the large CarD-like family of bacterial proteins, is vital for Myxococcus xanthus and differs functionally from the global transcriptional regulator CarD. Nucleic Acids Res (2010) 1.11

The receiver domain of FrzE, a CheA-CheY fusion protein, regulates the CheA histidine kinase activity and downstream signalling to the A- and S-motility systems of Myxococcus xanthus. Mol Microbiol (2008) 1.10

Antibiotic production by myxobacteria plays a role in predation. J Bacteriol (2011) 1.08

Identification of the cglC, cglD, cglE, and cglF genes and their role in cell contact-dependent gliding motility in Myxococcus xanthus. J Bacteriol (2012) 1.08

Myxobacteria, polarity, and multicellular morphogenesis. Cold Spring Harb Perspect Biol (2010) 1.07

The cognitive cell: bacterial behavior reconsidered. Front Microbiol (2015) 1.05

Genome sequence of the halotolerant marine bacterium Myxococcus fulvus HW-1. J Bacteriol (2011) 1.02

BacM, an N-terminally processed bactofilin of Myxococcus xanthus, is crucial for proper cell shape. Mol Microbiol (2011) 1.02

Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements. J Ind Microbiol Biotechnol (2013) 1.00

Identification of the Treponema pallidum subsp. pallidum TP0092 (RpoE) regulon and its implications for pathogen persistence in the host and syphilis pathogenesis. J Bacteriol (2012) 0.99

Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)). Stand Genomic Sci (2011) 0.99

Phosphorylation and dephosphorylation among Dif chemosensory proteins essential for exopolysaccharide regulation in Myxococcus xanthus. J Bacteriol (2010) 0.98

Phylogenetic and evolutionary patterns in microbial carotenoid biosynthesis are revealed by comparative genomics. PLoS One (2010) 0.96

Lipid body formation plays a central role in cell fate determination during developmental differentiation of Myxococcus xanthus. Mol Microbiol (2009) 0.96

Complete genome sequence of the fruiting myxobacterium Corallococcus coralloides DSM 2259. J Bacteriol (2012) 0.96

Xanthusbase: adapting wikipedia principles to a model organism database. Nucleic Acids Res (2006) 0.95

Are there lateral as well as polar engines for A-motile gliding in myxobacteria? J Bacteriol (2009) 0.95

Combinatorial regulation of genes essential for Myxococcus xanthus development involves a response regulator and a LysR-type regulator. Proc Natl Acad Sci U S A (2007) 0.95

Endemic social diversity within natural kin groups of a cooperative bacterium. Proc Natl Acad Sci U S A (2011) 0.94

Specificity residues determine binding affinity for two-component signal transduction systems. MBio (2013) 0.93

Tracking of chromosome and replisome dynamics in Myxococcus xanthus reveals a novel chromosome arrangement. PLoS Genet (2013) 0.92

A small predatory core genome in the divergent marine Bacteriovorax marinus SJ and the terrestrial Bdellovibrio bacteriovorus. ISME J (2012) 0.92

Draft Genome Sequence of Myxococcus xanthus Wild-Type Strain DZ2, a Model Organism for Predation and Development. Genome Announc (2013) 0.92

Differential expression of the three multicopper oxidases from Myxococcus xanthus. J Bacteriol (2007) 0.92

By their genes ye shall know them: genomic signatures of predatory bacteria. ISME J (2012) 0.91

Discovery of the autonomously replicating plasmid pMF1 from Myxococcus fulvus and development of a gene cloning system in Myxococcus xanthus. Appl Environ Microbiol (2008) 0.91

Combinatorial regulation by a novel arrangement of FruA and MrpC2 transcription factors during Myxococcus xanthus development. J Bacteriol (2009) 0.91

A vitamin B12-based system for conditional expression reveals dksA to be an essential gene in Myxococcus xanthus. J Bacteriol (2009) 0.91

Genome evolution and the emergence of fruiting body development in Myxococcus xanthus. PLoS One (2007) 0.91

Proteins associated with the Myxococcus xanthus extracellular matrix. J Bacteriol (2007) 0.90

Myxococcus xanthus viability depends on groEL supplied by either of two genes, but the paralogs have different functions during heat shock, predation, and development. J Bacteriol (2010) 0.90

Isolation and characterization of a suppressor mutation that restores Myxococcus xanthus exopolysaccharide production. Microbiology (2009) 0.90

Two systems for conditional gene expression in Myxococcus xanthus inducible by isopropyl-β-D-thiogalactopyranoside or vanillate. J Bacteriol (2012) 0.89

Chemotaxis as an emergent property of a swarm. J Bacteriol (2008) 0.89

A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program. Proc Natl Acad Sci U S A (2011) 0.89

Myxobacterium-produced antibiotic TA (myxovirescin) inhibits type II signal peptidase. Antimicrob Agents Chemother (2012) 0.88

Mechanisms involved in the functional divergence of duplicated GroEL chaperonins in Myxococcus xanthus DK1622. PLoS Genet (2013) 0.88

Seawater-regulated genes for two-component systems and outer membrane proteins in myxococcus. J Bacteriol (2009) 0.87

Expression and physiological role of three Myxococcus xanthus copper-dependent P1B-type ATPases during bacterial growth and development. Appl Environ Microbiol (2010) 0.87

FrzS regulates social motility in Myxococcus xanthus by controlling exopolysaccharide production. PLoS One (2011) 0.87

Combinatorial regulation by MrpC2 and FruA involves three sites in the fmgE promoter region during Myxococcus xanthus development. J Bacteriol (2011) 0.87

PCR detection of type I polyketide synthase genes in myxobacteria. Appl Environ Microbiol (2008) 0.87

Myxobacterial tools for social interactions. Res Microbiol (2012) 0.87

Mutations of the act promoter in Myxococcus xanthus. J Bacteriol (2006) 0.87

The Myxococcus xanthus Nla4 protein is important for expression of stringent response-associated genes, ppGpp accumulation, and fruiting body development. J Bacteriol (2007) 0.87

Improving conjugation efficacy of Sorangium cellulosum by the addition of dual selection antibiotics. J Ind Microbiol Biotechnol (2008) 0.87

CbpA: a polarly localized novel cyclic AMP-binding protein in Pseudomonas aeruginosa. J Bacteriol (2009) 0.86

Combinatorial regulation of fmgD by MrpC2 and FruA during Myxococcus xanthus development. J Bacteriol (2011) 0.86

Functional equivalence of HMGA- and histone H1-like domains in a bacterial transcriptional factor. Proc Natl Acad Sci U S A (2009) 0.86

Evolution of bacterial-like phosphoprotein phosphatases in photosynthetic eukaryotes features ancestral mitochondrial or archaeal origin and possible lateral gene transfer. Plant Physiol (2013) 0.86

New locus important for Myxococcus social motility and development. J Bacteriol (2007) 0.86

The lethal cargo of Myxococcus xanthus outer membrane vesicles. Front Microbiol (2014) 0.85

Biogeography and phylogenetic diversity of a cluster of exclusively marine myxobacteria. ISME J (2011) 0.85

Comprehensive set of integrative plasmid vectors for copper-inducible gene expression in Myxococcus xanthus. Appl Environ Microbiol (2012) 0.85

Characterization of 3'-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5'-Phosphate Capping Activity of RtcB3. J Bacteriol (2015) 0.85

Antibiotics from predatory bacteria. Beilstein J Org Chem (2016) 0.85

Comparative genomics of transport proteins in developmental bacteria: Myxococcus xanthus and Streptomyces coelicolor. BMC Microbiol (2013) 0.84

A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress. EMBO J (2014) 0.84

A CRISPR with roles in Myxococcus xanthus development and exopolysaccharide production. J Bacteriol (2014) 0.83

The Nla28S/Nla28 two-component signal transduction system regulates sporulation in Myxococcus xanthus. J Bacteriol (2012) 0.83

Global analysis of phase variation in Myxococcus xanthus. Mol Microbiol (2011) 0.83

Lessons learned from the transformation of natural product discovery to a genome-driven endeavor. J Ind Microbiol Biotechnol (2013) 0.83

A genetic screen in Myxococcus xanthus identifies mutants that uncouple outer membrane exchange from a downstream cellular response. J Bacteriol (2014) 0.82

Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a fruiting myxobacterium. Genome Announc (2013) 0.82

The mechanistic basis of Myxococcus xanthus rippling behavior and its physiological role during predation. PLoS Comput Biol (2012) 0.82

A barrier to homologous recombination between sympatric strains of the cooperative soil bacterium Myxococcus xanthus. ISME J (2016) 0.82

Draft Genome of a Type 4 Pilus Defective Myxococcus xanthus Strain, DZF1. Genome Announc (2013) 0.81

Nutrient-regulated proteolysis of MrpC halts expression of genes important for commitment to sporulation during Myxococcus xanthus development. J Bacteriol (2014) 0.81

Social bacteria and asocial eukaryotes. Environ Microbiol (2008) 0.81

DifA, a methyl-accepting chemoreceptor protein-like sensory protein, uses a novel signaling mechanism to regulate exopolysaccharide production in Myxococcus xanthus. J Bacteriol (2010) 0.81

Intra- and interprotein phosphorylation between two-hybrid histidine kinases controls Myxococcus xanthus developmental progression. J Biol Chem (2012) 0.81

Type IV pilus proteins form an integrated structure extending from the cytoplasm to the outer membrane. PLoS One (2013) 0.80

CarF mediates signaling by singlet oxygen, generated via photoexcited protoporphyrin IX, in Myxococcus xanthus light-induced carotenogenesis. J Bacteriol (2012) 0.80

Myxobacteria: Moving, Killing, Feeding, and Surviving Together. Front Microbiol (2016) 0.80

Identification of enhancer binding proteins important for Myxococcus xanthus development. J Bacteriol (2010) 0.80

Articles cited by this

Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol (2001) 66.87

The COG database: an updated version includes eukaryotes. BMC Bioinformatics (2003) 60.98

Improved microbial gene identification with GLIMMER. Nucleic Acids Res (1999) 51.34

Improved prediction of signal peptides: SignalP 3.0. J Mol Biol (2004) 48.40

The Pfam protein families database. Nucleic Acids Res (2000) 42.28

TIGRFAMs: a protein family resource for the functional identification of proteins. Nucleic Acids Res (2001) 20.84

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature (2002) 19.35

The PROSITE database, its status in 2002. Nucleic Acids Res (2002) 14.71

Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol (2005) 13.88

The origins of genome complexity. Science (2003) 12.25

PAS domains: internal sensors of oxygen, redox potential, and light. Microbiol Mol Biol Rev (1999) 10.69

Amelioration of bacterial genomes: rates of change and exchange. J Mol Evol (1997) 8.53

Asymmetric substitution patterns in the two DNA strands of bacteria. Mol Biol Evol (1996) 7.18

50 million years of genomic stasis in endosymbiotic bacteria. Science (2002) 6.65

Complete genome sequence of Caulobacter crescentus. Proc Natl Acad Sci U S A (2001) 5.58

Function of a bacterial activator protein that binds to transcriptional enhancers. Science (1989) 5.27

On some principles governing molecular evolution. Proc Natl Acad Sci U S A (1974) 4.97

Nutrition of Myxococcus xanthus, a fruiting myxobacterium. J Bacteriol (1978) 4.89

Compositional biases of bacterial genomes and evolutionary implications. J Bacteriol (1997) 4.85

The extracytoplasmic function (ECF) sigma factors. Adv Microb Physiol (2002) 4.65

Gene regulatory networks for development. Proc Natl Acad Sci U S A (2005) 4.45

The sigma 54 bacterial enhancer-binding protein family: mechanism of action and phylogenetic relationship of their functional domains. J Bacteriol (1993) 4.34

Trends between gene content and genome size in prokaryotic species with larger genomes. Proc Natl Acad Sci U S A (2004) 3.89

A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective. Science (2004) 3.87

Sculpting the proteome with AAA(+) proteases and disassembly machines. Cell (2004) 3.83

Cell density-dependent growth of Myxococcus xanthus on casein. J Bacteriol (1977) 3.65

Detecting anomalous gene clusters and pathogenicity islands in diverse bacterial genomes. Trends Microbiol (2001) 3.64

Lateral gene transfer and the origins of prokaryotic groups. Annu Rev Genet (2003) 3.50

Proteolysis in bacterial regulatory circuits. Annu Rev Cell Dev Biol (2003) 3.45

Regulation of secondary metabolism in streptomycetes. Curr Opin Microbiol (2005) 3.45

Evolutionary origins of genomic repertoires in bacteria. PLoS Biol (2005) 3.43

The genome sequence of the anaerobic, sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough. Nat Biotechnol (2004) 3.43

The Morphology and Cytology of Myxococcus xanthus, N. Sp. J Bacteriol (1941) 3.33

PAS: a multifunctional domain family comes to light. Curr Biol (1997) 3.20

Diversity in chemotaxis mechanisms among the bacteria and archaea. Microbiol Mol Biol Rev (2004) 3.15

Lineage-specific gene expansions in bacterial and archaeal genomes. Genome Res (2001) 3.10

One-component systems dominate signal transduction in prokaryotes. Trends Microbiol (2005) 3.09

The Myxococcus xanthus pilT locus is required for social gliding motility although pili are still produced. Mol Microbiol (1997) 2.91

Evolution of transcription factors and the gene regulatory network in Escherichia coli. Nucleic Acids Res (2003) 2.87

Phylogenomics: intersection of evolution and genomics. Science (2003) 2.86

Role of eukaryotic-type functional domains found in the prokaryotic enhancer receptor factor sigma 54. Cell (1990) 2.67

Domain architectures of sigma54-dependent transcriptional activators. J Bacteriol (2003) 2.57

A gene encoding a protein serine/threonine kinase is required for normal development of M. xanthus, a gram-negative bacterium. Cell (1991) 2.51

Cellular functions, mechanism of action, and regulation of FtsH protease. Annu Rev Microbiol (2005) 2.47

Bacteriolytic enzymes produced by Myxococcus xanthus. J Bacteriol (1972) 2.36

Signaling in myxobacteria. Annu Rev Microbiol (2004) 2.10

AAA+ proteins and substrate recognition, it all depends on their partner in crime. FEBS Lett (2002) 2.10

The bacterial enhancer-binding protein NTRC is a molecular machine: ATP hydrolysis is coupled to transcriptional activation. Genes Dev (1995) 2.09

Gene duplication and biased functional retention of paralogs in bacterial genomes. Trends Microbiol (2004) 1.94

Assessing evolutionary relationships among microbes from whole-genome analysis. Curr Opin Microbiol (2000) 1.77

A phylogenetic analysis of the myxobacteria: basis for their classification. Proc Natl Acad Sci U S A (1992) 1.51

The Myxococcus xanthus asgA gene encodes a novel signal transduction protein required for multicellular development. J Bacteriol (1995) 1.39

Characterization of the complex pdxH-tyrS operon of Escherichia coli K-12 and pleiotropic phenotypes caused by pdxH insertion mutations. J Bacteriol (1992) 1.38

Sigma54 enhancer binding proteins and Myxococcus xanthus fruiting body development. J Bacteriol (2004) 1.33

Comparative genomics of gene-family size in closely related bacteria. Genome Biol (2004) 1.31

Genetic studies of mrp, a locus essential for cellular aggregation and sporulation of Myxococcus xanthus. J Bacteriol (2001) 1.25

Exploitative and hierarchical antagonism in a cooperative bacterium. PLoS Biol (2005) 1.21

Sporulation timing in Myxococcus xanthus is controlled by the espAB locus. Mol Microbiol (1999) 1.20

The lonD gene is homologous to the lon gene encoding an ATP-dependent protease and is essential for the development of Myxococcus xanthus. J Bacteriol (1993) 1.20

Cloning and nucleotide sequence of the Myxococcus xanthus lon gene: indispensability of lon for vegetative growth. J Bacteriol (1993) 1.16

Analysis of myxobacterial secondary metabolism goes molecular. J Ind Microbiol Biotechnol (2006) 1.15

Enhancer-binding proteins with a forkhead-associated domain and the sigma54 regulon in Myxococcus xanthus fruiting body development. Proc Natl Acad Sci U S A (2005) 1.13

Restriction endonucleases: general survey procedure and survey of gliding bacteria. J Bacteriol (1978) 1.08

Inorganic polyphosphate in the social life of Myxococcus xanthus: motility, development, and predation. Proc Natl Acad Sci U S A (2005) 1.07

Behavioral analysis of single cells of Myxococcus xanthus in response to prey cells of Escherichia coli. FEMS Microbiol Lett (1996) 1.07

Identification and characterization of spdR mutations that bypass the BsgA protease-dependent regulation of developmental gene expression in Myxococcus xanthus. Mol Microbiol (2001) 1.04

A large family of eukaryotic-like protein Ser/Thr kinases of Myxococcus xanthus, a developmental bacterium. Microb Comp Genomics (2000) 1.04

Ancient lateral gene transfer in the evolution of Bdellovibrio bacteriovorus. Trends Microbiol (2006) 1.02

Biologically active secondary metabolites from myxobacteria. Biotechnol Adv (1993) 1.01

Myxococcus xanthus sasS encodes a sensor histidine kinase required for early developmental gene expression. J Bacteriol (1997) 0.98

Distinguishing features of delta-proteobacterial genomes. Proc Natl Acad Sci U S A (2006) 0.98

Identification and characterization of genes required for early Myxococcus xanthus developmental gene expression. J Bacteriol (2000) 0.95

Eukaryotic-like signaling and gene regulation in a prokaryote that undergoes multicellular development. Proc Natl Acad Sci U S A (2005) 0.91

ihfA gene of the bacterium Myxococcus xanthus and its role in activation of carotenoid genes by blue light. J Bacteriol (2001) 0.84

Genetic dissection of the light-inducible carQRS promoter region of Myxococcus xanthus. J Bacteriol (2004) 0.81

Articles by these authors

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell (1980) 23.17

Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science (2001) 21.99

TIGRFAMs: a protein family resource for the functional identification of proteins. Nucleic Acids Res (2001) 20.84

DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature (2000) 19.93

Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science (2000) 16.04

Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature (1999) 14.42

Biofilm formation as microbial development. Annu Rev Microbiol (2000) 13.33

A physical map of the human genome. Nature (2001) 12.39

Synergism between morphogenetic mutants of Myxococcus xanthus. Dev Biol (1978) 10.25

A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21. Science (1995) 9.79

Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains. J Bacteriol (2002) 8.88

Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis. Science (2003) 8.79

Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39. Nucleic Acids Res (2000) 8.69

Social gliding is correlated with the presence of pili in Myxococcus xanthus. Proc Natl Acad Sci U S A (1979) 8.66

Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440. Environ Microbiol (2002) 8.11

Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Nature (1999) 8.04

Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1. Science (1999) 8.01

Diffusion of autoinducer is involved in regulation of the Vibrio fischeri luminescence system. J Bacteriol (1985) 7.79

Cell-to-cell stimulation of movement in nonmotile mutants of Myxococcus. Proc Natl Acad Sci U S A (1977) 7.67

The DNA sequence and comparative analysis of human chromosome 20. Nature (2002) 7.40

The genome of the natural genetic engineer Agrobacterium tumefaciens C58. Science (2001) 6.90

Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis. J Clin Invest (1975) 6.25

Elevated blood pressures in mice lacking endothelial nitric oxide synthase. Proc Natl Acad Sci U S A (1996) 5.94

Construction of Tn5 lac, a transposon that fuses lacZ expression to exogenous promoters, and its introduction into Myxococcus xanthus. Proc Natl Acad Sci U S A (1984) 5.82

Myxobacteria: cell interactions, genetics, and development. Annu Rev Microbiol (1979) 5.80

Complete genome sequence of Caulobacter crescentus. Proc Natl Acad Sci U S A (2001) 5.58

Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function. J Am Coll Cardiol (1997) 5.33

A global analysis of developmentally regulated genes in Myxococcus xanthus. Dev Biol (1986) 5.21

Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58. Science (2001) 5.16

Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03

Nutrition of Myxococcus xanthus, a fruiting myxobacterium. J Bacteriol (1978) 4.89

Type IV pili and cell motility. Mol Microbiol (1999) 4.87

Genome sequence, comparative analysis, and population genetics of the domestic horse. Science (2009) 4.41

Fruiting body morphogenesis in submerged cultures of Myxococcus xanthus. J Bacteriol (1982) 4.29

Tomato Prf is a member of the leucine-rich repeat class of plant disease resistance genes and lies embedded within the Pto kinase gene cluster. Cell (1996) 4.29

Introduction of transposon Tn5 into Myxococcus for analysis of developmental and other nonselectable mutants. Proc Natl Acad Sci U S A (1981) 4.19

Monophyletic origins of the metazoa: an evolutionary link with fungi. Science (1993) 4.18

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell (1995) 4.17

The brief MAST: a shortened version of the Michigan Alcoholism Screening Test. Am J Psychiatry (1972) 4.12

Analysis of vertebrate SCL loci identifies conserved enhancers. Nat Biotechnol (2000) 4.01

Antibacterial agents based on the cyclic D,L-alpha-peptide architecture. Nature (2001) 4.00

Induction of coordinated movement of Myxococcus xanthus cells. J Bacteriol (1982) 3.98

Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene. Nat Genet (1998) 3.94

Developmental cell interactions in Myxococcus xanthus and the spoC locus. Proc Natl Acad Sci U S A (1983) 3.92

Microbial genes in the human genome: lateral transfer or gene loss? Science (2001) 3.87

Localized secretion of acid phosphatase reflects the pattern of cell surface growth in Saccharomyces cerevisiae. J Cell Biol (1980) 3.84

Systematic isolation of transducing phages for Myxococcus xanthus. Virology (1978) 3.76

Expression of many developmentally regulated genes in Myxococcus depends on a sequence of cell interactions. Genes Dev (1987) 3.76

Genome of Geobacter sulfurreducens: metal reduction in subsurface environments. Science (2003) 3.68

Genetic and functional evidence that Type IV pili are required for social gliding motility in Myxococcus xanthus. Mol Microbiol (1995) 3.58

Intercellular signaling is required for developmental gene expression in Myxococcus xanthus. Dev Biol (1986) 3.52

Enrichment of gene-coding sequences in maize by genome filtration. Science (2003) 3.41

In situ transposon replacement and isolation of a spontaneous tandem genetic duplication. Mol Gen Genet (1983) 3.33

Phospholipid model membranes. I. Structural characteristics of hydrated liquid crystals. Biochim Biophys Acta (1967) 3.29

Calcium-induced lysozyme secretion from human polymorphonuclear leukocytes. Biochem Biophys Res Commun (1974) 3.24

Uptake of homologous single-stranded fragments by superhelical DNA: a possible mechanism for initiation of genetic recombination. Proc Natl Acad Sci U S A (1975) 3.19

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med (2001) 3.07

Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization. J Cell Biol (2000) 3.07

Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. J Biol Chem (1992) 3.03

Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A. Proc Natl Acad Sci U S A (1997) 2.99

Photocontrol of the Functional Coupling between Photosynthesis and Stomatal Conductance in the Intact Leaf : Blue Light and Par-Dependent Photosystems in Guard Cells. Plant Physiol (1982) 2.92

The Myxococcus xanthus pilT locus is required for social gliding motility although pili are still produced. Mol Microbiol (1997) 2.91

Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function. J Cell Biol (1998) 2.80

Integrating smoking cessation into routine public prenatal care: the Smoking Cessation in Pregnancy project. Am J Public Health (1995) 2.78

Different clinical features of aortic intramural hematoma versus dissection involving the ascending aorta. J Am Coll Cardiol (2001) 2.77

Evidence that the superoxide-generating system of human leukocytes is associated with the cell surface. J Clin Invest (1977) 2.77

C-factor: a cell-cell signaling protein required for fruiting body morphogenesis of M. xanthus. Cell (1990) 2.73

Yeast secretory mutants that block the formation of active cell surface enzymes. J Cell Biol (1984) 2.71

Does confirmatory tumor biopsy alter the management of breast cancer patients with distant metastases? Ann Oncol (2009) 2.71

A quantitative assay for bacterial RNA polymerases. J Biol Chem (1979) 2.70

Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions. Biochem Biophys Res Commun (1998) 2.67

Developmental cell interactions of Myxococcus xanthus: analysis of mutants. J Bacteriol (1983) 2.58

Regulation of expression of the pilA gene in Myxococcus xanthus. J Bacteriol (1997) 2.53

Reproductive and neonatal losses associated with possible encephalomyocarditis virus infection in pigs. Vet Rec (1990) 2.52

Idiopathic transverse myelitis: MR characteristics. AJNR Am J Neuroradiol (1996) 2.48

DNA sequences of the tail fiber genes of bacteriophage P2: evidence for horizontal transfer of tail fiber genes among unrelated bacteriophages. J Bacteriol (1992) 2.45

The DNA sequence and biological annotation of human chromosome 1. Nature (2006) 2.42

PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction. Kidney Int (2001) 2.41

Renal histopathology of stone-forming patients with distal renal tubular acidosis. Kidney Int (2007) 2.36

Growth factors and stromal matrix proteins associated with mammographic densities. Cancer Epidemiol Biomarkers Prev (2001) 2.35

SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus. J Biol Chem (1988) 2.35

Cell interactions in myxobacterial growth and development. Science (1985) 2.35

Murein components rescue developmental sporulation of Myxococcus xanthus. J Bacteriol (1982) 2.31

GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae. J Bacteriol (1986) 2.30

Sequenced strains must be saved from extinction. Nature (2001) 2.29