Published in J Mol Biol on December 15, 2006
Cofilin dissociates Arp2/3 complex and branches from actin filaments. Curr Biol (2009) 1.98
Remodeling of actin filaments by ADF/cofilin proteins. Proc Natl Acad Sci U S A (2011) 1.60
ADF/cofilin regulates actomyosin assembly through competitive inhibition of myosin II binding to F-actin. Dev Cell (2012) 1.20
Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease. Hum Mol Genet (2011) 1.10
Mapping the cofilin binding site on yeast G-actin by chemical cross-linking. J Mol Biol (2008) 1.09
Toxofilin from Toxoplasma gondii forms a ternary complex with an antiparallel actin dimer. Proc Natl Acad Sci U S A (2007) 1.02
Plant Actin-Depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes throughout Evolution. Plant Cell (2017) 0.98
Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data. Proc Natl Acad Sci U S A (2007) 0.98
Modeling of protein binary complexes using structural mass spectrometry data. Protein Sci (2007) 0.93
The effects of ADF/cofilin and profilin on the conformation of the ATP-binding cleft of monomeric actin. Biophys J (2009) 0.85
Cofilin-induced changes in F-actin detected via cross-linking with benzophenone-4-maleimide. Biochemistry (2013) 0.80
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J Mol Biol (2008) 3.27
Molecular details of cAMP generation in mammalian cells: a tale of two systems. J Mol Biol (2006) 2.05
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Hum Mol Genet (2002) 2.05
Latrunculin B or ATP depletion induces cofilin-dependent translocation of actin into nuclei of mast cells. J Biol Chem (2003) 1.65
Proteomic approaches for discovering biomarkers of diabetic nephropathy. Nephrol Dial Transplant (2010) 1.64
The prevalence of proteolytic antibodies against factor VIII in hemophilia A. N Engl J Med (2002) 1.62
Determining the differences in actin binding by human ADF and cofilin. J Mol Biol (2002) 1.61
Lsh is involved in de novo methylation of DNA. EMBO J (2006) 1.57
SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol Cell (2013) 1.52
Selective upregulation of beta1-adrenergic receptors and dephosphorylation of troponin I in end-stage heart failure patients supported by ventricular assist devices. J Mol Cell Cardiol (2006) 1.50
Solution structure of human cofilin: actin binding, pH sensitivity, and relationship to actin-depolymerizing factor. J Biol Chem (2003) 1.50
Crystal structure of the guanylyl cyclase Cya2. Proc Natl Acad Sci U S A (2008) 1.44
Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1. Eukaryot Cell (2006) 1.41
Regulation of the pollen-specific actin-depolymerizing factor LlADF1. Plant Cell (2002) 1.40
Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells. Nat Cell Biol (2006) 1.37
Lsh controls Hox gene silencing during development. Proc Natl Acad Sci U S A (2007) 1.31
Functional effects of protein kinase C-mediated myofilament phosphorylation in human myocardium. Cardiovasc Res (2005) 1.30
A molecular mechanism for direct sirtuin activation by resveratrol. PLoS One (2012) 1.26
The two ADF-H domains of twinfilin play functionally distinct roles in interactions with actin monomers. Mol Biol Cell (2002) 1.24
Assay for measurement of intact B-type natriuretic peptide prohormone in blood. Clin Chem (2006) 1.22
Discontinuous epitope prediction based on mimotope analysis. Bioinformatics (2006) 1.22
Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium. Basic Res Cardiol (2009) 1.20
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle. Circ Res (2006) 1.19
Crystal structure of the human CCA-adding enzyme: insights into template-independent polymerization. J Mol Biol (2003) 1.19
Structure-based development of novel sirtuin inhibitors. Aging (Albany NY) (2011) 1.19
Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism. Proc Natl Acad Sci U S A (2013) 1.18
Dietary restriction: standing up for sirtuins. Science (2010) 1.17
Role of tropomyosin isoforms in the calcium sensitivity of striated muscle thin filaments. J Muscle Res Cell Motil (2007) 1.15
CO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicans. PLoS Pathog (2010) 1.15
Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background. J Mol Cell Cardiol (2010) 1.14
Determinants of enzymatic specificity in the Cys-Met-metabolism PLP-dependent enzymes family: crystal structure of cystathionine gamma-lyase from yeast and intrafamiliar structure comparison. Biol Chem (2003) 1.10
Peptide decoys selected by phage display block in vitro and in vivo activity of a human anti-FVIII inhibitor. Blood (2003) 1.09
Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiency. Metabolism (2002) 1.08
Human metastasis regulator protein H-prune is a short-chain exopolyphosphatase. Biochemistry (2008) 1.08
A phosphodiesterase 2A isoform localized to mitochondria regulates respiration. J Biol Chem (2011) 1.07
The Lifespan-regulator p66Shc in mitochondria: redox enzyme or redox sensor? Antioxid Redox Signal (2010) 1.06
An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms. Nat Commun (2013) 1.05
Activation of the lifespan regulator p66Shc through reversible disulfide bond formation. Proc Natl Acad Sci U S A (2008) 1.05
Sirt1 activation by resveratrol is substrate sequence-selective. Aging (Albany NY) (2013) 1.04
Nuclear localisation of the G-actin sequestering peptide thymosin beta4. J Cell Sci (2004) 1.03
Association of ATRX with pericentric heterochromatin and the Y chromosome of neonatal mouse spermatogonia. BMC Mol Biol (2008) 1.02
Differential regulation of the actomyosin interaction by skeletal and cardiac troponin isoforms. J Biol Chem (2002) 1.01
Structure-based development of novel adenylyl cyclase inhibitors. J Med Chem (2008) 0.97
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate. Proc Natl Acad Sci U S A (2014) 0.96
PEPOP: computational design of immunogenic peptides. BMC Bioinformatics (2008) 0.96
Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition. PLoS One (2012) 0.96
Activated cofilin colocalises with Arp2/3 complex in apoptotic blebs during programmed cell death. Eur J Cell Biol (2005) 0.95
Function and regulation of the mitochondrial sirtuin isoform Sirt5 in Mammalia. Biochim Biophys Acta (2009) 0.95
Emerging mitochondrial signaling mechanisms in physiology, aging processes, and as drug targets. Exp Gerontol (2010) 0.93
Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans. J Mol Biol (2008) 0.93
Application of the Spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding. J Immunol Methods (2002) 0.93
DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development. Epigenetics (2008) 0.92
SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy (2015) 0.91
Identification of Peroxiredoxin 1 as a novel interaction partner for the lifespan regulator protein p66Shc. Aging (Albany NY) (2009) 0.90
Cellulose membrane supported peptide arrays for deciphering protein-protein interaction sites: the case of PIN, a protein with multiple natural partners. Mol Divers (2004) 0.90
Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity. Eur J Biochem (2003) 0.90
Structures, substrates, and regulators of Mammalian sirtuins - opportunities and challenges for drug development. Front Pharmacol (2012) 0.90
A peptide mimetic of an anti-CD4 monoclonal antibody by rational design. Biochem Biophys Res Commun (2003) 0.89
The central region of human T-cell leukemia virus type 1 Tax protein contains distinct domains involved in subunit dimerization. J Virol (2003) 0.89
Secretory products of guinea pig epicardial fat induce insulin resistance and impair primary adult rat cardiomyocyte function. J Cell Mol Med (2011) 0.89
Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa. J Mol Biol (2011) 0.88
Epitope spreading of the anti-CYP2D6 antibody response in patients with autoimmune hepatitis and in the CYP2D6 mouse model. J Autoimmun (2011) 0.88
Crystal structure analysis of human Sirt2 and its ADP-ribose complex. J Struct Biol (2013) 0.88
Proteomic analysis of the cellular responses induced in uninfected immune cells by cell-expressed X4 HIV-1 envelope. Proteomics (2007) 0.88
Gelsolin domains 4-6 in active, actin-free conformation identifies sites of regulatory calcium ions. J Mol Biol (2003) 0.88
Mapping of IgE-binding epitopes on the major latex allergen Hev b 2 and the cross-reacting 1,3beta-glucanase fruit allergens as a molecular basis for the latex-fruit syndrome. Mol Immunol (2009) 0.87
Gene and protein markers of diabetic nephropathy. Nephrol Dial Transplant (2007) 0.87
Detection of anti-p53 antibodies by ELISA using p53 synthetic or phage-displayed peptides. J Immunol Methods (2002) 0.87
Mutational analyses of the p35-caspase interaction. A bowstring kinetic model of caspase inhibition by p35. J Biol Chem (2002) 0.87
Simultaneous detection and epitope mapping of anti-factor VIII antibodies. Thromb Haemost (2008) 0.86
Anti-factor VIII antibodies: a 2005 update. Thromb Haemost (2005) 0.86
Antibody-antigenic peptide interactions monitored by SPR and QCM-D. A model for SPR detection of IA-2 autoantibodies in human serum. Biosens Bioelectron (2007) 0.85
Mapping and conformational analysis of IgE-binding epitopic regions on the molecular surface of the major Ara h 3 legumin allergen of peanut (Arachis hypogaea). Mol Immunol (2008) 0.85
Association of genetic variations in TCF7L2, SLC30A8, HHEX, LOC387761, and EXT2 with Type 2 diabetes mellitus in Tunisia. Genet Test Mol Biomarkers (2011) 0.85
Production of monoclonal antibodies capable of neutralizing dermonecrotic activity of Loxosceles intermedia spider venom and their use in a specific immunometric assay. Toxicon (2003) 0.84
Identification of new sphingomyelinases D in pathogenic fungi and other pathogenic organisms. PLoS One (2013) 0.84
A description scheme of biological processes based on elementary bricks of action. J Mol Biol (2004) 0.84
Phosphorylation of human cardiac troponin I G203S and K206Q linked to familial hypertrophic cardiomyopathy affects actomyosin interaction in different ways. J Mol Cell Cardiol (2003) 0.84
Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol. Biosci Rep (2013) 0.83
Identification of a haem domain in human soluble adenylate cyclase. Biosci Rep (2012) 0.83
Protein kinase C contributes to the maintenance of contractile force in human ventricular cardiomyocytes. J Biol Chem (2008) 0.83
Low molecular weight peptides restore the procoagulant activity of factor VIII in the presence of the potent inhibitor antibody ESH8. J Biol Chem (2002) 0.82
Duration of Maternal Antibodies against Canine Distemper Virus and Hendra Virus in Pteropid Bats. PLoS One (2013) 0.82
Allergenicity of Hev b 13, a major esterase allergen in natural rubber latex (Hevea brasiliensis) allergy, does not only depend on its carbohydrate moiety. Mol Immunol (2009) 0.81
Monoclonal antibody 76F distinguishes IA-2 from IA-2beta and overlaps an autoantibody epitope. J Autoimmun (2006) 0.81
Monoclonal antibody 667 recognizes the variable region A motif of the ecotropic retrovirus CasBrE envelope glycoprotein and inhibits Env binding to the viral receptor. J Virol (2003) 0.81
Characteristics, mechanisms of action, and epitope mapping of anti-factor VIII antibodies. Clin Rev Allergy Immunol (2009) 0.81
Inhibition of the human deacylase Sirtuin 5 by the indole GW5074. Bioorg Med Chem Lett (2012) 0.81
Carbonic anhydrase inhibitors: inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions. Bioorg Med Chem Lett (2008) 0.81
Dual effects of staurosporine on A431 and NRK cells: microfilament disassembly and uncoordinated lamellipodial activity followed by cell death. Eur J Cell Biol (2006) 0.81