Published in Biochemistry on November 18, 1975
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Insulin-induced receptor loss in cultured human lymphocytes is due to accelerated receptor degradation. Proc Natl Acad Sci U S A (1981) 2.18
Effect of microtubular or translational inhibitors on general cell protein degradation. Evidence for a dual catabolic pathway. Biochem J (1977) 1.93
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Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes Dev (1999) 4.07
A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes. Biochem Biophys Res Commun (1978) 3.92
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol (2001) 3.87
Latent growth curves within developmental structural equation models. Child Dev (1987) 3.79
Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc Natl Acad Sci U S A (1980) 3.75
Ubiquitin: roles in protein modification and breakdown. Cell (1983) 3.19
ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation. Proc Natl Acad Sci U S A (1980) 2.96
Studies on the degradation of tyrosine aminotransferase in hepatoma cells in culture. Influence of the composition of the medium and adenosine triphosphate dependence. J Biol Chem (1971) 2.83
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Immunochemical analysis of the turnover of ubiquitin-protein conjugates in intact cells. Relationship to the breakdown of abnormal proteins. J Biol Chem (1982) 2.56
Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes. Proc Natl Acad Sci U S A (1987) 2.52
Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase. Proc Natl Acad Sci U S A (1995) 2.48
Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP. Proc Natl Acad Sci U S A (1979) 2.37
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"Covalent affinity" purification of ubiquitin-activating enzyme. J Biol Chem (1982) 2.15
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase. Proc Natl Acad Sci U S A (1997) 2.08
Specificity of binding of NH2-terminal residue of proteins to ubiquitin-protein ligase. Use of amino acid derivatives to characterize specific binding sites. J Biol Chem (1988) 2.04
The ubiquitin pathway for the degradation of intracellular proteins. Prog Nucleic Acid Res Mol Biol (1986) 1.98
Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20. Biochem Biophys Res Commun (1999) 1.93
ATP-dependent degradation of ubiquitin-protein conjugates. Proc Natl Acad Sci U S A (1984) 1.92
ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin. Proc Natl Acad Sci U S A (1989) 1.82
Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint. Biochem Biophys Res Commun (2000) 1.74
The protein substrate binding site of the ubiquitin-protein ligase system. J Biol Chem (1986) 1.72
The mouse and human genes encoding the recognition component of the N-end rule pathway. Proc Natl Acad Sci U S A (1998) 1.72
E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins. Proc Natl Acad Sci U S A (1996) 1.70
Factors affecting epithelial hyperplasia after photorefractive keratectomy. J Cataract Refract Surg (1997) 1.69
Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults: a systematic review and economic evaluation. Health Technol Assess (2005) 1.64
A multicomponent system that degrades proteins conjugated to ubiquitin. Resolution of factors and evidence for ATP-dependent complex formation. J Biol Chem (1988) 1.60
Outflow resistance of enucleated human eyes at two different perfusion pressures and different extents of trabeculotomy. Curr Eye Res (1989) 1.58
Excimer laser photorefractive keratectomy for myopia. Clinical results in sighted eyes. Ophthalmology (1993) 1.54
Evaluation of four maternal smoking questions. Public Health Rep (1999) 1.52
Characterization of the heat-stable polypeptide of the ATP-dependent proteolytic system from reticulocytes. J Biol Chem (1980) 1.51
Role of the alpha-amino group of protein in ubiquitin-mediated protein breakdown. Proc Natl Acad Sci U S A (1984) 1.49
A ubiquitin C-terminal isopeptidase that acts on polyubiquitin chains. Role in protein degradation. J Biol Chem (1992) 1.48
Activation of the heat-stable polypeptide of the ATP-dependent proteolytic system. Proc Natl Acad Sci U S A (1981) 1.48
Failure of mechanical epithelial removal to reverse persistent hyperopia after photorefractive keratectomy. J Refract Surg (1997) 1.46
Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas. Cancer (2001) 1.44
Affinity purification of ubiquitin-protein ligase on immobilized protein substrates. Evidence for the existence of separate NH2-terminal binding sites on a single enzyme. J Biol Chem (1990) 1.43
Post-translational cleavage of polypeptide chains: role in assembly. Annu Rev Biochem (1975) 1.42
Relationship of the pool of intracellular valine to protein synthesis and degradation in cultured cells. J Biol Chem (1976) 1.40
Ubiquitin C-terminal hydrolase activity associated with the 26 S protease complex. J Biol Chem (1993) 1.28
Binding sites of ubiquitin-protein ligase. Binding of ubiquitin-protein conjugates and of ubiquitin-carrier protein. J Biol Chem (1989) 1.27
Regulation of the synthesis of 5-phosphoribosyl-I-pyrophosphate in intact red blood cells and in cell-free preparations. Biochim Biophys Acta (1969) 1.22
Stapled haemorrhoidectomy (haemorrhoidopexy) for the treatment of haemorrhoids: a systematic review and economic evaluation. Health Technol Assess (2008) 1.22
Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis: a systematic review and economic evaluation. Health Technol Assess (2011) 1.16
A ubiquitin-protein ligase specific for type III protein substrates. J Biol Chem (1990) 1.16
Identification of the active amino acid residue of the polypeptide of ATP-dependent protein breakdown. J Biol Chem (1981) 1.14
The clinical course of acquired complete heart block in children with acute myocarditis. Pediatr Cardiol (2003) 1.12
Influence of protease inhibitors and energy metabolism on intracellular protein breakdown in starving Escherichia coli. Biochem Biophys Res Commun (1973) 1.12
A high molecular weight protease in liver cytosol. J Biol Chem (1979) 1.09
Assembly of the 26 S complex that degrades proteins ligated to ubiquitin is accompanied by the formation of ATPase activity. J Biol Chem (1990) 1.08
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The UK Endovascular Aneurysm Repair (EVAR) trials: design, methodology and progress. Eur J Vasc Endovasc Surg (2004) 1.06
Evaluation of the effectiveness of professionals and nonprofessionals as instructors of "coping with depression" classes for elders. Gerontologist (1983) 1.04
Binding of activated cyclosome to p13(suc1). Use for affinity purification. J Biol Chem (1997) 1.03
Endovascular stents for abdominal aortic aneurysms: a systematic review and economic model. Health Technol Assess (2009) 0.99
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The cost-effectiveness of adjuvant chemotherapy for early breast cancer: A comparison of no chemotherapy and first, second, and third generation regimens for patients with differing prognoses. Eur J Cancer (2011) 0.97
Role of Suc1 in the activation of the cyclosome by protein kinase Cdk1/cyclin B. Biochem Biophys Res Commun (1999) 0.94
Regulation of intracellular protein breakdown in stringent and relaxed strains of E. coli,. Cell (1974) 0.94
Evaluation of the chest radiograph in the emergency department patient. Emerg Med Clin North Am (1985) 0.94
Role of epithelial hyperplasia in regression following photorefractive keratectomy. Br J Ophthalmol (1996) 0.94
The action of histamine on the respiratory tract. J Physiol (1932) 0.93
Protein turnover in senescent cultured chick embryo fibroblasts. J Cell Physiol (1978) 0.90
DOPA compared with dihydroxyfumarate as co-factor in peroxidase-mediated oxidation of tyrosine to melanin. Histochemical studies with neutrophils, eosinophils, mast cells, melanoma cells and neurons. Histochemie (1971) 0.90
Biochemical studies of the peroxidase-mediated oxidation of tyrosine to melanin: demonstration of the hydroxylation of tyrosine by plant and human peroxidases. Biochem J (1971) 0.90
The effect of a multidisciplinary team approach on weight gain in nonorganic failure-to-thrive children. J Dev Behav Pediatr (1991) 0.90
Long-term results of photorefractive keratectomy for hyperopia and hyperopic astigmatism. J Refract Surg (1998) 0.90
Turnover of purine nucleotides in rabbit erythrocytes. II. Studies in vitro. Biochim Biophys Acta (1967) 0.89
Hydrogeologic assessment of exposure to solvent-contaminated drinking water: pregnancy outcomes in relation to exposure. Arch Environ Health (1990) 0.88
A comparative assessment of endothelium from pseudophakic and phakic donor corneas stored in organ culture. Br J Ophthalmol (2002) 0.87
Patient satisfaction following photorefractive keratectomy for myopia. J Refract Surg (1995) 0.87
Roles of protein synthesis and tRNA aminoacylation in the regulation of intracellular protein breakdown in E. coli. Biochem Biophys Res Commun (1974) 0.86
Pregnancy outcomes in women potentially exposed to solvent-contaminated drinking water in San Jose, California. Am J Epidemiol (1990) 0.86
Paroxetine associated hepatotoxicity: a report of 3 cases and a review of the literature. Pharmacopsychiatry (2002) 0.85
Antibodies against the VRT101 laminin epitope correlate with human SLE disease activity and can be removed by extracorporeal immunoadsorption. Rheumatology (Oxford) (2007) 0.84
Efficacy of cobalt chelates in the rabbit eye model for epithelial herpetic keratitis. Cornea (1998) 0.84
Epithelial alterations following photorefractive keratectomy for myopia. J Refract Surg (1995) 0.84
Increased formation of 5-phosphoriboxyl-1-pyrophosphate in red blood cells of some gouty patients. Isr J Med Sci (1969) 0.84
Dyspnea differentiation index: A new method for the rapid separation of cardiac vs pulmonary dyspnea. Chest (1999) 0.83
Low positive predictive value of the ABCD2 score in emergency department transient ischaemic attack diagnoses: the South Western Sydney transient ischaemic attack study. Intern Med J (2012) 0.83
Excimer laser photorefractive keratectomy for presbyopia: 24-month follow-up in three eyes. J Refract Surg (1998) 0.82
Therapeutic drug monitoring in methadone maintenance: choosing a matrix. J Addict Dis (2001) 0.82
Photorefractive keratectomy to correct myopic or hyperopic astigmatism with a cross-cylinder ablation. J Refract Surg (1999) 0.81
The oxidant effect of isouramil on red cell glutathione and its synergistic enhancement by ascorbic acid or 3,4-dihydroxyphenylalanine. Possible relation to the pathogenesis of favism. Isr J Med Sci (1969) 0.81
Malaria: failure, puzzle, challenge. Perspect Health (1999) 0.81
Cost-effectiveness of laparoscopic fundoplication versus continued medical management for the treatment of gastro-oesophageal reflux disease based on long-term follow-up of the REFLUX trial. Br J Surg (2013) 0.79
A comparative study of epithelial hyperplasia after PRK: Summit versus VISX in the same patient. Acta Ophthalmol Scand (1996) 0.79
Tuberculosis in an inflammatory bowel disease cohort from South Africa. S Afr Med J (2012) 0.79