Published in Bioinformatics on January 31, 2007
PhenoLink--a web-tool for linking phenotype to ~omics data for bacteria: application to gene-trait matching for Lactobacillus plantarum strains. BMC Genomics (2012) 1.02
US and Scottish health professionals' attitudes toward DNA biobanking. J Am Med Inform Assoc (2008) 0.87
An approach to identifying drug resistance associated mutations in bacterial strains. BMC Genomics (2012) 0.86
Explaining microbial phenotypes on a genomic scale: GWAS for microbes. Brief Funct Genomics (2013) 0.85
Cladograms with Path to Event (ClaPTE): a novel algorithm to detect associations between genotypes or phenotypes using phylogenies. Comput Biol Med (2014) 0.75
GWAMAR: genome-wide assessment of mutations associated with drug resistance in bacteria. BMC Genomics (2014) 0.75
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. J Biol Chem (2005) 3.53
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation (2010) 2.78
Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors. Mol Biol Cell (2008) 2.73
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genomics (2005) 2.68
Whole-genome sequence-based analysis of high-density lipoprotein cholesterol. Nat Genet (2013) 2.62
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A (2010) 2.47
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia. Blood (2012) 1.97
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation (2011) 1.96
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet (2012) 1.84
Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study. J Hypertens (2011) 1.81
GRASSIUS: a platform for comparative regulatory genomics across the grasses. Plant Physiol (2008) 1.72
Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet (2012) 1.68
Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease. Circ Cardiovasc Genet (2010) 1.64
Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. Am J Hum Genet (2012) 1.60
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Hum Mol Genet (2010) 1.53
Acquisition of germ plasm accelerates vertebrate evolution. Science (2014) 1.53
Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart study. Circulation (2010) 1.47
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol (2014) 1.45
Dopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins. Cell Mol Life Sci (2010) 1.45
Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet (2009) 1.41
PRIMe: a method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies. Bioinformatics (2011) 1.39
Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score. J Clin Oncol (2013) 1.34
Theta reset produces optimal conditions for long-term potentiation. Hippocampus (2004) 1.33
Eco-virological approach for assessing the role of wild birds in the spread of avian influenza H5N1 along the Central Asian Flyway. PLoS One (2012) 1.27
Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet (2013) 1.27
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood (2012) 1.26
Mechanically probing the folding pathway of single RNA molecules. Biophys J (2003) 1.23
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet (2012) 1.23
Regulation of the nucleosome unwrapping rate controls DNA accessibility. Nucleic Acids Res (2012) 1.18
Small RNAs in tomato fruit and leaf development. Biochim Biophys Acta (2007) 1.18
A systems biology framework identifies molecular underpinnings of coronary heart disease. Arterioscler Thromb Vasc Biol (2013) 1.18
Epigenetic marks in somatic chromatin are remodelled to resemble pluripotent nuclei by amphibian oocyte extracts. Epigenetics (2009) 1.14
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet (2012) 1.14
Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood (2011) 1.13
Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet (2011) 1.11
Identification of cytoplasmic capping targets reveals a role for cap homeostasis in translation and mRNA stability. Cell Rep (2012) 1.10
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr (2013) 1.08
Gene expression signatures of coronary heart disease. Arterioscler Thromb Vasc Biol (2013) 1.08
Hybrid alignment: high-performance with universal statistics. Bioinformatics (2002) 1.07
Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells. Mol Cancer Ther (2007) 1.06
Evolution of drug resistance in multiple distinct lineages of H5N1 avian influenza. Infect Genet Evol (2008) 1.06
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. Am J Hum Genet (2012) 1.05
Axolotl Nanog activity in mouse embryonic stem cells demonstrates that ground state pluripotency is conserved from urodele amphibians to mammals. Development (2010) 1.05
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest (2013) 1.04
Differential nuclear remodeling of mammalian somatic cells by Xenopus laevis oocyte and egg cytoplasm. Exp Cell Res (2005) 1.02
Contribution of ribosomal residues to P-site tRNA binding. Nucleic Acids Res (2009) 1.01
Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset. Hum Mol Genet (2013) 1.00
Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. PLoS Genet (2012) 1.00
Clinical and genetic correlates of growth differentiation factor 15 in the community. Clin Chem (2012) 0.99
Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study. Physiol Genomics (2011) 0.98
A quantitative model of nucleosome dynamics. Nucleic Acids Res (2011) 0.97
Reprogramming somatic cells into stem cells. Reproduction (2006) 0.95
Semi-quantitative immunohistochemical detection of 5-hydroxymethyl-cytosine reveals conservation of its tissue distribution between amphibians and mammals. Epigenetics (2012) 0.95
A Scalable, Flexible Workflow for MethylCap-Seq Data Analysis. IEEE Int Workshop Genomic Signal Process Stat (2011) 0.94
5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development. Epigenetics (2012) 0.94
Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes. Hum Mol Genet (2013) 0.93
Short-read, high-throughput sequencing technology for STR genotyping. Biotech Rapid Dispatches (2012) 0.93
Discovery of new genes and deletion editing in Physarum mitochondria enabled by a novel algorithm for finding edited mRNAs. Nucleic Acids Res (2005) 0.93
Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion. J Clin Invest (2014) 0.93
Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet (2014) 0.93
RAD51 protein ATP cap regulates nucleoprotein filament stability. J Biol Chem (2012) 0.92
The flexibility of locally melted DNA. Nucleic Acids Res (2009) 0.91
Methods for high-throughput MethylCap-Seq data analysis. BMC Genomics (2012) 0.91
Epigenetic reprogramming of breast cancer cells with oocyte extracts. Mol Cancer (2011) 0.90
Translocation of structured polynucleotides through nanopores. Phys Biol (2004) 0.90
Simple is beautiful: a straightforward approach to improve the delineation of true and false positives in PSI-BLAST searches. Bioinformatics (2008) 0.90
Gene expression in the axolotl germ line: Axdazl, Axvh, Axoct-4, and Axkit. Dev Dyn (2004) 0.90
A practical approach to significance assessment in alignment with gaps. J Comput Biol (2006) 0.89
An extract of Morinda citrifolia interferes with the serum-induced formation of filamentous structures in Candida albicans and inhibits germination of Aspergillus nidulans. Am J Chin Med (2006) 0.89
Different regions of HIV-1 subtype C env are associated with placental localization and in utero mother-to-child transmission. J Virol (2011) 0.89
Model for codon position bias in RNA editing. Phys Rev Lett (2005) 0.88
Evolution of germ cell development in tetrapods: comparison of urodeles and amniotes. Evol Dev (2009) 0.88
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause. Hum Mol Genet (2013) 0.88
Molecular analysis of H7 avian influenza viruses from Australia and New Zealand: genetic diversity and relationships from 1976 to 2007. J Virol (2010) 0.88
Quasispecies of bovine enteric and respiratory coronaviruses based on complete genome sequences and genetic changes after tissue culture adaptation. Virology (2007) 0.87
Formation of the open complex by bacterial RNA polymerase--a quantitative model. Biophys J (2008) 0.86
Sex- and age-interacting eQTLs in human complex diseases. Hum Mol Genet (2013) 0.86
A performance enhanced PSI-BLAST based on hybrid alignment. Bioinformatics (2010) 0.86
An XML-based system for synthesis of data from disparate databases. J Am Med Inform Assoc (2006) 0.86
An extended IUPAC nomenclature code for polymorphic nucleic acids. Bioinformatics (2010) 0.86
Enrichment-based DNA methylation analysis using next-generation sequencing: sample exclusion, estimating changes in global methylation, and the contribution of replicate lanes. BMC Genomics (2012) 0.86
A conserved mechanism for vertebrate mesoderm specification in urodele amphibians and mammals. Dev Biol (2010) 0.85
Genome annotation in the presence of insertional RNA editing. Bioinformatics (2008) 0.85
SIB-BLAST: a web server for improved delineation of true and false positives in PSI-BLAST searches. Nucleic Acids Res (2009) 0.84