Published in Epigenetics on April 16, 2009
Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation. Proc Natl Acad Sci U S A (2010) 2.01
Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process? Nat Rev Mol Cell Biol (2011) 1.58
Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3. Cell Mol Life Sci (2010) 1.25
Mammalian nuclear transplantation to Germinal Vesicle stage Xenopus oocytes - a method for quantitative transcriptional reprogramming. Methods (2010) 1.17
Nuclear transfer to eggs and oocytes. Cold Spring Harb Perspect Biol (2011) 1.13
A combined epigenetic and non-genetic approach for reprogramming human somatic cells. PLoS One (2010) 1.01
Pig epiblast stem cells depend on activin/nodal signaling for pluripotency and self-renewal. Stem Cells Dev (2010) 0.96
Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes. Epigenetics Chromatin (2010) 0.93
Epigenetic reprogramming of breast cancer cells with oocyte extracts. Mol Cancer (2011) 0.90
A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina. Vision Res (2010) 0.86
Combined analysis of DNA methylation and cell cycle in cancer cells. Epigenetics (2015) 0.83
An oncologist׳s friend: How Xenopus contributes to cancer research. Dev Biol (2015) 0.81
CHD1L Regulated PARP1-Driven Pluripotency and Chromatin Remodeling During the Early-Stage Cell Reprogramming. Stem Cells (2015) 0.78
Regulated Expression of Chromobox Homolog 5 Revealed in Tumors of Apc(Min) (/+) ROSA11 Gene Trap Mice. G3 (Bethesda) (2012) 0.77
Siberian Sturgeon Oocyte Extract Induces Epigenetic Modifications of Porcine Somatic Cells and Improves Developmental Competence of SCNT Embryos. Asian-Australas J Anim Sci (2014) 0.77
Proteomic analysis of early reprogramming events in murine somatic cells incubated with Xenopus laevis oocyte extracts demonstrates network associations with induced pluripotency markers. Cell Reprogram (2013) 0.76
Epigenetic reprogramming of human lung cancer cells with the extract of bovine parthenogenetic oocytes. J Cell Mol Med (2014) 0.76
Reprogramming of round spermatids by the germinal vesicle cytoplasm in mice. PLoS One (2013) 0.75
Combined positive effect of oocyte extracts and brilliant cresyl blue stained recipient cytoplasts on epigenetic reprogramming and gene expression in buffalo nuclear transfer embryos. Cytotechnology (2017) 0.75
Cell-free extract from porcine induced pluripotent stem cells can affect porcine somatic cell nuclear reprogramming. J Reprod Dev (2015) 0.75
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. J Biol Chem (2005) 3.53
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proc Natl Acad Sci U S A (2007) 3.24
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation (2010) 2.78
Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors. Mol Biol Cell (2008) 2.73
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genomics (2005) 2.68
Whole-genome sequence-based analysis of high-density lipoprotein cholesterol. Nat Genet (2013) 2.62
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A (2010) 2.47
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability. Stem Cells (2006) 2.20
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation (2011) 1.96
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet (2012) 1.84
Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study. J Hypertens (2011) 1.81
Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet (2012) 1.68
Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease. Circ Cardiovasc Genet (2010) 1.64
Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. Am J Hum Genet (2012) 1.60
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Hum Mol Genet (2010) 1.53
Acquisition of germ plasm accelerates vertebrate evolution. Science (2014) 1.53
Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart study. Circulation (2010) 1.47
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol (2014) 1.45
Dopamine receptor 1 localizes to neuronal cilia in a dynamic process that requires the Bardet-Biedl syndrome proteins. Cell Mol Life Sci (2010) 1.45
Gene-specific vulnerability to imprinting variability in human embryonic stem cell lines. Genome Res (2007) 1.41
Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet (2009) 1.41
PRIMe: a method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies. Bioinformatics (2011) 1.39
Theta reset produces optimal conditions for long-term potentiation. Hippocampus (2004) 1.33
Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet (2013) 1.27
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood (2012) 1.26
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet (2012) 1.23
A gene expression atlas of the domestic pig. BMC Biol (2012) 1.18
A systems biology framework identifies molecular underpinnings of coronary heart disease. Arterioscler Thromb Vasc Biol (2013) 1.18
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet (2012) 1.14
Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood (2011) 1.13
Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet (2011) 1.11
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr (2013) 1.08
Gene expression signatures of coronary heart disease. Arterioscler Thromb Vasc Biol (2013) 1.08
The health profile of cloned animals. Nat Biotechnol (2002) 1.07
Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells. Mol Cancer Ther (2007) 1.06
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. Am J Hum Genet (2012) 1.05
Axolotl Nanog activity in mouse embryonic stem cells demonstrates that ground state pluripotency is conserved from urodele amphibians to mammals. Development (2010) 1.05
Common culture conditions for maintenance and cardiomyocyte differentiation of the human embryonic stem cell lines, BG01 and HUES-7. Int J Dev Biol (2006) 1.04
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest (2013) 1.04
Differential nuclear remodeling of mammalian somatic cells by Xenopus laevis oocyte and egg cytoplasm. Exp Cell Res (2005) 1.02
Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction? Reprod Biomed Online (2005) 1.01
Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset. Hum Mol Genet (2013) 1.00
Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. PLoS Genet (2012) 1.00
Clinical and genetic correlates of growth differentiation factor 15 in the community. Clin Chem (2012) 0.99
Gene expression analysis of whole blood, peripheral blood mononuclear cells, and lymphoblastoid cell lines from the Framingham Heart Study. Physiol Genomics (2011) 0.98
Pig epiblast stem cells depend on activin/nodal signaling for pluripotency and self-renewal. Stem Cells Dev (2010) 0.96
Semi-quantitative immunohistochemical detection of 5-hydroxymethyl-cytosine reveals conservation of its tissue distribution between amphibians and mammals. Epigenetics (2012) 0.95
Reprogramming somatic cells into stem cells. Reproduction (2006) 0.95
Overcoming drug resistance and treating advanced prostate cancer. Curr Drug Targets (2012) 0.95
5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development. Epigenetics (2012) 0.94
Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes. Hum Mol Genet (2013) 0.93
Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet (2014) 0.93
Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion. J Clin Invest (2014) 0.93
Large scale genotype-phenotype correlation analysis based on phylogenetic trees. Bioinformatics (2007) 0.91
Modulation of pluripotency in the porcine embryo and iPS cells. PLoS One (2012) 0.90
Gene expression in the axolotl germ line: Axdazl, Axvh, Axoct-4, and Axkit. Dev Dyn (2004) 0.90
Epigenetic reprogramming of breast cancer cells with oocyte extracts. Mol Cancer (2011) 0.90
An extract of Morinda citrifolia interferes with the serum-induced formation of filamentous structures in Candida albicans and inhibits germination of Aspergillus nidulans. Am J Chin Med (2006) 0.89
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause. Hum Mol Genet (2013) 0.88
Evolution of germ cell development in tetrapods: comparison of urodeles and amniotes. Evol Dev (2009) 0.88
Epigenetic reprogramming in the porcine germ line. BMC Dev Biol (2011) 0.88
Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos. Epigenetics (2008) 0.87
Sex- and age-interacting eQTLs in human complex diseases. Hum Mol Genet (2013) 0.86
An extended IUPAC nomenclature code for polymorphic nucleic acids. Bioinformatics (2010) 0.86
An XML-based system for synthesis of data from disparate databases. J Am Med Inform Assoc (2006) 0.86
A conserved mechanism for vertebrate mesoderm specification in urodele amphibians and mammals. Dev Biol (2010) 0.85
Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits. Hypertension (2012) 0.84
Aberrant nucleo-cytoplasmic cross-talk results in donor cell mtDNA persistence in cloned embryos. Genetics (2006) 0.84
Expression of Dazl and Vasa in turtle embryos and ovaries: evidence for inductive specification of germ cells. Evol Dev (2009) 0.84
Contrasting effects of in vitro fertilization and nuclear transfer on the expression of mtDNA replication factors. Genetics (2007) 0.83
Stem cell plasticity in development and cancer: epigenetic origin of cancer stem cells. Subcell Biochem (2013) 0.82
Bovine somatic cell nuclear transfer using recipient oocytes recovered by ovum pick-up: effect of maternal lineage of oocyte donors. Biol Reprod (2002) 0.82
The androgen receptor and stem cell pathways in prostate and bladder cancers (review). Int J Oncol (2011) 0.81
Inferring developmental constraint and constraint release: primordial germ cell determination mechanisms as examples. J Theor Biol (2007) 0.79
Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs). BMC Genomics (2015) 0.78
A systematic heritability analysis of the human whole blood transcriptome. Hum Genet (2015) 0.78
Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies. BMC Proc (2009) 0.78
Erratum: Whole-genome sequence-based analysis of thyroid function. Nat Commun (2015) 0.77
Derivation and characterisation of the human embryonic stem cell lines, NOTT1 and NOTT2. In Vitro Cell Dev Biol Anim (2010) 0.77
Ecto-diadenosine polyphosphates hydrolase activity on human prostasomes. Prostate (2002) 0.77
5-Carboxylcytosine is localized to euchromatic regions in the nuclei of follicular cells in axolotl ovary. Nucleus (2012) 0.77