PubRank

Simon J Boulton

Author PubWeight™ 94.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Playing the end game: DNA double-strand break repair pathway choice. Mol Cell 2012 5.42
2 RTEL1 maintains genomic stability by suppressing homologous recombination. Cell 2008 3.84
3 Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science 2009 3.68
4 Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature 2008 3.67
5 A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol Cell 2007 3.23
6 RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol Cell 2013 3.05
7 Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Mol Cell 2010 2.91
8 Inhibition of homologous recombination by the PCNA-interacting protein PARI. Mol Cell 2011 2.61
9 A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites. EMBO J 2006 2.41
10 MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism. Science 2012 2.39
11 RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell 2012 2.24
12 FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex. Mol Cell 2008 2.14
13 Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Curr Biol 2002 2.06
14 NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies. Mol Cell 2013 1.97
15 Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans. EMBO J 2005 1.94
16 FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J Biol Chem 2008 1.93
17 Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair. Mol Cell 2010 1.90
18 HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability. Nat Cell Biol 2007 1.77
19 HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis. Dev Cell 2008 1.76
20 RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair. Mol Cell Biol 2005 1.74
21 RTEL-1 enforces meiotic crossover interference and homeostasis. Science 2010 1.70
22 Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast. Genes Dev 2008 1.68
23 HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature 2013 1.57
24 BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair. J Cell Sci 2012 1.55
25 DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair. Mol Cell Biol 2007 1.53
26 Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates. PLoS Genet 2009 1.52
27 CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability. Mol Cell 2010 1.51
28 The choice in meiosis - defining the factors that influence crossover or non-crossover formation. J Cell Sci 2011 1.49
29 Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res 2007 1.48
30 CeBRC-2 stimulates D-loop formation by RAD-51 and promotes DNA single-strand annealing. J Mol Biol 2006 1.42
31 Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways. DNA Repair (Amst) 2008 1.33
32 Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2. Proc Natl Acad Sci U S A 2007 1.30
33 Replication blocking lesions present a unique substrate for homologous recombination. EMBO J 2007 1.29
34 The centriolar satellite protein Cep131 is important for genome stability. J Cell Sci 2012 1.27
35 RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res 2010 1.27
36 RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science 2013 1.21
37 C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair. DNA Repair (Amst) 2006 1.14
38 Tandem immunoaffinity purification of protein complexes from Caenorhabditis elegans. Biotechniques 2004 1.13
39 Emerging links between the biological clock and the DNA damage response. Chromosoma 2007 1.12
40 Meiotic recombination in Caenorhabditis elegans. Chromosome Res 2007 1.08
41 Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis. PLoS Genet 2013 1.06
42 A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome. PLoS Genet 2013 1.05
43 Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates. EMBO Rep 2006 0.98
44 BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair. EMBO Rep 2008 0.97
45 The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans. EMBO J 2009 0.93
46 C. elegans: a model of Fanconi anemia and ICL repair. Mutat Res 2008 0.92
47 Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein. J Biol Chem 2013 0.89
48 BRCA1 ubiquitylation of CtIP: Just the tIP of the iceberg? DNA Repair (Amst) 2006 0.89
49 Alternative induction of meiotic recombination from single-base lesions of DNA deaminases. Genetics 2009 0.89
50 The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling. Cell Cycle 2014 0.88
51 Metabolism of postsynaptic recombination intermediates. FEBS Lett 2010 0.82
52 High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins. Biochem Biophys Res Commun 2003 0.81
53 FANCM-FAAP24 and HCLK2: roles in ATR signalling and the Fanconi anemia pathway. Cell Cycle 2009 0.78
54 Helicase and translocases required for the maintenance of genome stability. DNA Repair (Amst) 2010 0.77
55 DNA repair: Decision at the break point. Nature 2010 0.77
56 FANCM: fork pause, rewind and play. EMBO J 2010 0.77
57 DNA repair: A heavyweight joins the fray. Nature 2009 0.76
58 Differential regulation of the PIKK kinase family by Tel2. Cell Cycle 2008 0.76
59 How to exchange your partner. Workshop on recombination mechanisms and the maintenance of genomic stability. EMBO Rep 2006 0.75
60 TRF2 Recruits RTEL1 to Telomeres in S Phase to Promote T-Loop Unwinding. Mol Cell 2016 0.75
61 RTEL1 Inhibits Trinucleotide Repeat Expansions and Fragility. Cell Rep 2016 0.75
62 Erratum: Molecular basis of telomere dysfunction in human genetic diseases. Nat Struct Mol Biol 2017 0.75