Published in Development on April 04, 2007
Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma. J Clin Invest (2012) 1.57
Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems. J Biol Chem (2010) 1.32
F3/contactin and TAG1 play antagonistic roles in the regulation of sonic hedgehog-induced cerebellar granule neuron progenitor proliferation. Development (2011) 0.87
Lrp4: A novel modulator of extracellular signaling in craniofacial organogenesis. Am J Med Genet A (2010) 0.84
Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma. PLoS One (2015) 0.79
Low-density Lipoprotein Receptor-related Proteins in a Novel Mechanism of Axon Guidance and Peripheral Nerve Regeneration. J Biol Chem (2015) 0.78
Low Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell Function. Stem Cells Int (2016) 0.77
Newly generated cells are increased in hippocampus of adult mice lacking a serine protease inhibitor. BMC Neurosci (2010) 0.77
Proteoglycans specify Sonic Hedgehog effect. Nat Neurosci (2009) 0.75
Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation. Glia (2016) 0.75
Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages. Oncotarget (2016) 0.75
Hematoxylin and eosin staining of tissue and cell sections. CSH Protoc (2008) 2.80
Progression of vertebrate limb development through SHH-mediated counteraction of GLI3. Science (2002) 2.45
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis. Development (2004) 2.39
Tissue remodelling through branching morphogenesis. Nat Rev Mol Cell Biol (2009) 2.06
Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods (2010) 2.05
Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proc Natl Acad Sci U S A (2010) 1.96
Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis. Dev Cell (2009) 1.81
Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc Natl Acad Sci U S A (2003) 1.79
Luminal mitosis drives epithelial cell dispersal within the branching ureteric bud. Dev Cell (2013) 1.79
Transparency in Research involving Animals: The Basel Declaration and new principles for reporting research in BJP manuscripts. Br J Pharmacol (2015) 1.79
Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development (2007) 1.72
Anticoagulant and antithrombotic properties of platelet protease nexin-1. Blood (2009) 1.62
Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev (2002) 1.61
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes Dev (2004) 1.60
A self-regulatory system of interlinked signaling feedback loops controls mouse limb patterning. Science (2009) 1.58
Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients. Hum Mol Genet (2010) 1.52
Impaired fear extinction in mice lacking protease nexin-1. Eur J Neurosci (2010) 1.44
The dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6). Ann Neurol (2010) 1.36
Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet (2010) 1.35
Vertebrate limb development: moving from classical morphogen gradients to an integrated 4-dimensional patterning system. Cold Spring Harb Perspect Biol (2009) 1.31
SHH pathway and cerebellar development. Cerebellum (2009) 1.28
The eIF4E RNA regulon promotes the Akt signaling pathway. J Cell Biol (2008) 1.22
Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling. Development (2006) 1.22
Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function. J Neurochem (2008) 1.21
The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression. Cancer Res (2009) 1.20
Paraffin embedding tissue samples for sectioning. CSH Protoc (2008) 1.18
Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression. Dev Growth Differ (2007) 1.16
Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol (2010) 1.15
Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts. PLoS One (2010) 1.14
Mouse Twist is required for fibroblast growth factor-mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis. Mech Dev (2002) 1.08
GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. Dev Cell (2012) 1.07
Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer. Mol Cell Biol (2008) 1.06
Reduced mobility of fibroblast growth factor (FGF)-deficient myoblasts might contribute to dystrophic changes in the musculature of FGF2/FGF6/mdx triple-mutant mice. Mol Cell Biol (2003) 1.03
SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling. Development (2011) 0.95
Transsynaptic coordination of synaptic growth, function, and stability by the L1-type CAM Neuroglian. PLoS Biol (2013) 0.95
The molecular basis of human congenital limb malformations. Wiley Interdiscip Rev Dev Biol (2012) 0.95
Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning in Xenopus embryos. Development (2003) 0.95
Tenascin-W is a novel marker for activated tumor stroma in low-grade human breast cancer and influences cell behavior. Cancer Res (2007) 0.94
Liver regeneration in FGF-2-deficient mice: VEGF acts as potential functional substitute for FGF-2. Liver Int (2004) 0.92
Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds. Development (2012) 0.91
Tenascin-W is a specific marker of glioma-associated blood vessels and stimulates angiogenesis in vitro. FASEB J (2009) 0.90
Conserved cis-regulatory regions in a large genomic landscape control SHH and BMP-regulated Gremlin1 expression in mouse limb buds. BMC Dev Biol (2012) 0.90
Genetic interaction of Gli3 and Alx4 during limb development. Int J Dev Biol (2005) 0.90
PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1. Parkinsons Dis (2011) 0.89
Genetic correction of DNA repair-deficient/cancer-prone xeroderma pigmentosum group C keratinocytes. Hum Gene Ther (2003) 0.89
Regulation of brain proteolytic activity is necessary for the in vivo function of NMDA receptors. J Neurosci (2004) 0.87
Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1. J Cell Biochem (2006) 0.87
PTCH1 +/- dermal fibroblasts isolated from healthy skin of Gorlin syndrome patients exhibit features of carcinoma associated fibroblasts. PLoS One (2009) 0.87
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos. Development (2012) 0.87
Specific processing of tenascin-C by the metalloprotease meprinbeta neutralizes its inhibition of cell spreading. Matrix Biol (2009) 0.86
Cryosectioning tissues. CSH Protoc (2008) 0.85
Thrombin in ischemic neuronal death. Exp Neurol (2006) 0.85
Cutting sections of paraffin-embedded tissues. CSH Protoc (2008) 0.85
Tenascin-W, a new marker of cancer stroma, is elevated in sera of colon and breast cancer patients. Int J Cancer (2008) 0.84
Patterning the limb before and after SHH signalling. J Anat (2003) 0.84
Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells. J Cell Sci (2008) 0.82
Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos. PLoS One (2011) 0.82
The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney. Dev Biol (2011) 0.82
Tenascin-W: an extracellular matrix protein associated with osteogenesis and cancer. Int J Biochem Cell Biol (2010) 0.82
Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush. J Neurosci (2007) 0.82
The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation (2013) 0.82
ATAD2B is a phylogenetically conserved nuclear protein expressed during neuronal differentiation and tumorigenesis. Dev Growth Differ (2010) 0.81
Fixation and permeabilization of cells and tissues. CSH Protoc (2008) 0.81
Endogenous protease nexin-1 protects against cerebral ischemia. Int J Mol Sci (2013) 0.80
1 Patterning the limb before and after SHH. J Anat (2002) 0.80
Reciprocal regulation of urokinase receptor (CD87)-mediated cell adhesion by plasminogen activator inhibitor-1 and protease nexin-1. J Cell Sci (2003) 0.80
Making sense-data-based simulations of vertebrate limb development. Curr Opin Genet Dev (2012) 0.79
Inhibition of PDGF-BB by Factor VII-activating protease (FSAP) is neutralized by protease nexin-1, and the FSAP-inhibitor complexes are internalized via LRP. Biochem J (2007) 0.79
The role of serine proteases and serine protease inhibitors in the migration of gonadotropin-releasing hormone neurons. BMC Dev Biol (2002) 0.79
Dual requirement of ectodermal Smad4 during AER formation and termination of feedback signaling in mouse limb buds. Genesis (2013) 0.78
Developmental biology: first come, first served. Nature (2002) 0.78
Prothrombin overexpressed in post-natal neurones requires blood factors for activation in the mouse brain. J Neurochem (2004) 0.78
Preparation of slides and coverslips for microscopy. CSH Protoc (2008) 0.78
Newly generated cells are increased in hippocampus of adult mice lacking a serine protease inhibitor. BMC Neurosci (2010) 0.77
Mounting live cells attached to coverslips for microscopy. CSH Protoc (2008) 0.77
From cells to organs: new insight into organ morphogenesis. Curr Opin Genet Dev (2009) 0.77
FGF2 signaling is required for the development of neuronal circuits regulating blood pressure. Circ Res (2002) 0.76
Proteoglycans specify Sonic Hedgehog effect. Nat Neurosci (2009) 0.75
Dissecting and culturing and imaging the mouse urogenital system. Methods Mol Biol (2012) 0.75
Immunohistochemical staining of dpERK staining during early kidney development. Methods Mol Biol (2012) 0.75
Media for mounting fixed cells on microscope slides. CSH Protoc (2008) 0.75
Isolation of high quality RNA from embryonic kidney and cells. Methods Mol Biol (2012) 0.75
Decalcifying tissues for paraffin embedding. CSH Protoc (2008) 0.75